Rps3l1 (ribosomal protein S3 like 1) - Rat Genome Database

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Gene: Rps3l1 (ribosomal protein S3 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rps3l1 (Ensembl: RGD1560831)
Name: ribosomal protein S3 like 1 (Ensembl:similar to 40S ribosomal protein S3)
RGD ID: 1560831
Description: Predicted to enable DNA binding activity; RNA binding activity; and class I DNA-(apurinic or apyrimidinic site) endonuclease activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in several processes, including DNA repair; regulation of translation; and translation. Predicted to be located in cytosolic ribosome and mitochondrial inner membrane. Predicted to be part of small ribosomal subunit; INTERACTS WITH ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 40S ribosomal protein S3-like; LOC499803; RGD1560831; similar to 40S ribosomal protein S3; small ribosomal subunit protein uS3-like
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8371,967,699 - 71,968,537 (-)NCBIGRCr8
mRatBN7.2351,559,683 - 51,560,522 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl351,559,683 - 51,560,524 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0352,997,847 - 52,998,669 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0359,616,260 - 59,617,088 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4348,862,928 - 48,863,734 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera351,135,933 - 51,136,749 (-)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Rps3l1
17 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32824968773249687Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32824968773249687Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32824968773249687Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32824968773249687Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32846857173468571Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33068464275684642Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33142640370668733Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33142640370668733Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33142640370668733Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33142640370668733Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33142640370668733Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33142640370668733Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33370334761017857Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
634317Bw117Body weight QTL 1173.58abdominal fat pad mass (VT:1000711)abdominal fat pad weight to body weight ratio (CMO:0000095)33945463753296578Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)33945463762951183Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000009988   ⟹   ENSRNOP00000009988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl351,559,683 - 51,560,524 (-)Ensembl
Rnor_6.0 Ensembl352,997,922 - 52,998,650 (-)Ensembl
RefSeq Acc Id: XM_039106339   ⟹   XP_038962267
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8371,967,699 - 71,968,537 (-)NCBI
mRatBN7.2351,559,683 - 51,560,522 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038962267 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000009988
  ENSRNOP00000009988.1
  ENSRNOP00000023935.4
RefSeq Acc Id: XP_038962267   ⟸   XM_039106339
- UniProtKB: D3ZVH2 (UniProtKB/TrEMBL),   A0A8L2QCG7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000009988   ⟸   ENSRNOT00000009988
Protein Domains
KH type-2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZVH2-F1-model_v2 AlphaFold D3ZVH2 1-243 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560831 AgrOrtholog
BioCyc Gene G2FUF-49536 BioCyc
Ensembl Genes ENSRNOG00000007605 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000017418 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009988.4 UniProtKB/TrEMBL
  ENSRNOT00000023935.6 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1140.32 UniProtKB/TrEMBL
  3.30.300.20 UniProtKB/TrEMBL
InterPro KH_dom-like_a/b UniProtKB/TrEMBL
  KH_dom_type_2 UniProtKB/TrEMBL
  KH_sf_prok-type UniProtKB/TrEMBL
  Ribosomal_S3_C UniProtKB/TrEMBL
  Ribosomal_S3_C_sf UniProtKB/TrEMBL
  Ribosomal_S3_CS UniProtKB/TrEMBL
  Ribosomal_S3_euk/arc UniProtKB/TrEMBL
NCBI Gene 499803 ENTREZGENE
PANTHER 30S/40S RIBOSOMAL PROTEIN S3 UniProtKB/TrEMBL
  40S RIBOSOMAL PROTEIN S3 UniProtKB/TrEMBL
Pfam KH_2 UniProtKB/TrEMBL
  Ribosomal_S3_C UniProtKB/TrEMBL
PhenoGen Rps3l1 PhenoGen
PROSITE KH_TYPE_2 UniProtKB/TrEMBL
  RIBOSOMAL_S3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007605 RatGTEx
  ENSRNOG00000017418 RatGTEx
Superfamily-SCOP SSF54814 UniProtKB/TrEMBL
  SSF54821 UniProtKB/TrEMBL
UniProt A0A8L2QCG7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZVH2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Rps3l1  ribosomal protein S3 like 1  RGD1560831  similar to 40S ribosomal protein S3  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1560831  similar to 40S ribosomal protein S3   RGD1560831_predicted  similar to 40S ribosomal protein S3 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560831_predicted  similar to 40S ribosomal protein S3 (predicted)  LOC499803  similar to 40S ribosomal protein S3  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499803  similar to 40S ribosomal protein S3      Symbol and Name status set to provisional 70820 PROVISIONAL