potassium inwardly-rectifying channel, subfamily J, member 3
RGD ID:
2958
Description:
Enables voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential. Involved in response to electrical stimulus. Located in T-tubule and external side of plasma membrane. Orthologous to human KCNJ3 (potassium inwardly rectifying channel subfamily J member 3); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Duloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA] and Duloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA]
Amoxapine results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA] and Amoxapine results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA]
Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium]
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KCNJ3 mRNA
[NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KCNJ3 mRNA
Ethanol results in increased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] and Sertraline inhibits the reaction [Ethanol results in increased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA]]
Ethanol promotes the reaction [[KCNJ3 protein binds to KCNJ6 protein] which results in increased transport of Potassium] and Ethosuximide inhibits the reaction [Ethanol promotes the reaction [[KCNJ3 protein binds to KCNJ6 protein] which results in increased transport of Potassium]]
Ethosuximide inhibits the reaction [[KCNJ5 protein binds to KCNJ3 protein] which results in increased transport of Potassium] and Ethosuximide inhibits the reaction [Ethanol promotes the reaction [[KCNJ3 protein binds to KCNJ6 protein] which results in increased transport of Potassium]]
Fluoxetine inhibits the reaction [[KCNJ3 protein co-treated with KCNJ5 protein] results in increased transport of Potassium] and Fluoxetine inhibits the reaction [[KCNJ3 protein co-treated with KCNJ6 protein] results in increased transport of Potassium]
Mianserin affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA] and Mianserin affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA]
mirtazapine affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA] and mirtazapine affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA]
nefazodone affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA] and nefazodone affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA]
[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KCNJ3 mRNA
[NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KCNJ3 mRNA
[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KCNJ3 mRNA
Scopolamine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium]
Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium]
Tropicamide inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium]
Venlafaxine Hydrochloride affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA] and Venlafaxine Hydrochloride affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA]
Identification of the structural determinant responsible for the phosphorylation of G-protein activated potassium channel 1 by cAMP-dependent protein kinase.
Alteration in expression of G-protein-activated inward rectifier K+-channel subunits GIRK1 and GIRK2 in the rat brain following electroconvulsive shock.