Gene: Kcnj3 (potassium voltage-gated channel subfamily J member 3) Rattus norvegicus
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Symbol: Kcnj3
Name: potassium voltage-gated channel subfamily J member 3
Description: ENCODES a protein that exhibits inward rectifier potassium channel activity (ortholog); INVOLVED IN response to electrical stimulus; potassium ion import across plasma membrane (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN cell surface; external side of plasma membrane; T-tubule; INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; acrylamide
AGR Description: Predicted to have inward rectifier potassium channel activity; involved in response to electrical stimulus; localizes to the T-tubule and external side of plasma membrane; orthologous to human KCNJ3 (potassium voltage-gated channel subfamily J member 3).
Merged Description: Predicted to have inward rectifier potassium channel activity; involved in response to electrical stimulus; localizes to the T-tubule and external side of plasma membrane; orthologous to human KCNJ3 (potassium voltage-gated channel subfamily J member 3); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: G protein-activated inward rectifier potassium channel 1; GIRK-1; GIRK1; inward rectifier K(+) channel Kir3.1; KGA; KGB1; potassium channel inwarding rectifying channel subfamily J member 3; potassium channel subunit Kir3.1 type 3 delta; potassium channel, inwardly rectifying subfamily J member 3; potassium channel, inwardly rectifying subfamily J, member 3; potassium inwardly-rectifying channel subfamily J member 3; potassium inwardly-rectifying channel, subfamily J, member 3
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0341,019,898 - 41,181,070 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0346,103,695 - 46,264,737 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4337,068,672 - 37,256,990 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1870,763,612 - 70,766,543 (+)NCBI
Celera338,059,571 - 38,220,833 (+)NCBICelera
Cytogenetic Map3q21NCBI
RH 3.4 Map3507.0RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kcnj3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2958
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.