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Gene: KCNJ3 (potassium inwardly rectifying channel subfamily J member 3) Canis lupus familiaris

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Symbol:

KCNJ3

Name:

potassium inwardly rectifying channel subfamily J member 3

RGD ID:

12304097

Description:

ENCODES a protein that exhibits phosphatidylinositol-4,5-bisphosphate binding (ortholog); voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential (ortholog); INVOLVED IN response to electrical stimulus (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); T-tubule (ortholog); INTERACTS WITH acetylcholine; barium(0); potassium atom

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

G protein-activated inward rectifier potassium channel 1; potassium inwardly-rectifying channel, subfamily J, member 3; potassium voltage-gated channel subfamily J member 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	36	1,354,686 - 1,496,397 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	36	1,354,678 - 1,493,766 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	36	1,385,232 - 1,526,573 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	36	1,366,227 - 1,507,708 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	36	1,366,153 - 1,507,279 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	36	1,374,461 - 1,515,573 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	36	1,435,400 - 1,577,189 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	36	1,478,631 - 1,620,408 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

acetylcholine (EXP)

barium(0) (EXP)

potassium atom (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

monoatomic cation transmembrane transport (IEA)

monoatomic ion transmembrane transport (IEA)

monoatomic ion transport (IEA)

potassium ion import across plasma membrane (IBA,IEA)

potassium ion transmembrane transport (IEA)

potassium ion transport (IEA)

regulation of monoatomic ion transmembrane transport (IBA)

response to electrical stimulus (ISO)

Cellular Component

cell surface (ISO)

external side of plasma membrane (ISO)

I(KACh) inward rectifier potassium channel complex (IEA)

inward rectifier potassium channel complex (IEA)

membrane (IEA)

monoatomic ion channel complex (IEA)

parallel fiber to Purkinje cell synapse (IEA)

plasma membrane (IBA)

presynaptic membrane (IEA)

T-tubule (ISO)

voltage-gated potassium channel complex (IEA)

Molecular Function

G-protein activated inward rectifier potassium channel activity (IEA)

inward rectifier potassium channel activity (IBA,IEA)

phosphatidylinositol-4,5-bisphosphate binding (ISO)

protein binding (ISO)

voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

acebutolol pharmacodynamics pathway (ISO)

adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway (ISO)

amiodarone pharmacodynamics pathway (ISO)

amlodipine pharmacodynamics pathway (ISO)

atenolol pharmacodynamics pathway (ISO)

betaxolol pharmacodynamics pathway (ISO)

bisoprolol pharmacodynamics pathway (ISO)

bupranolol drug pathway (ISO)

bupranolol pharmacodynamics pathway (ISO)

carvedilol pharmacodynamics pathway (ISO)

diltiazem pharmacodynamics pathway (ISO)

disopyramide pharmacodynamics pathway (ISO)

dobutamine pharmacodynamics pathway (ISO)

esmolol pharmacodynamics pathway (ISO)

flecainde pharmacodynamics pathway (ISO)

fosphenytoin pharmacodynamics pathway (ISO)

ibutilide pharmacodynamics pathway (ISO)

isoprenaline pharmacodynamics pathway (ISO)

isradipine pharmacodynamics pathway (ISO)

levobunolol pharmacodynamics pathway (ISO)

lidocaine pharmacodynamics pathway (ISO)

metoprolol pharmacodynamics pathway (ISO)

mexiletine pharmacodynamics pathway (ISO)

nadolol pharmacodynamics pathway (ISO)

nebivolol pharmacodynamics pathway (ISO)

nifedipine pharmacodynamics pathway (ISO)

nimodipine pharmacodynamics pathway (ISO)

nisoldipine pharmacodynamics pathway (ISO)

nitrendipine pharmacodynamics pathway (ISO)

penbutolol pharmacodynamics pathway (ISO)

phenytoin pharmacodynamics pathway (ISO)

pindolol pharmacodynamics pathway (ISO)

procainamide pharmacodynamics pathway (ISO)

propranolol pharmacodynamics pathway (ISO)

quinidine pharmacodynamics pathway (ISO)

sotalol pharmacodynamics pathway (ISO)

timolol pharmacodynamics pathway (ISO)

verapamil pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

KCNJ3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	36	1,354,686 - 1,496,397 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	36	1,354,678 - 1,493,766 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	36	1,385,232 - 1,526,573 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	36	1,366,227 - 1,507,708 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	36	1,366,153 - 1,507,279 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	36	1,374,461 - 1,515,573 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	36	1,435,400 - 1,577,189 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	36	1,478,631 - 1,620,408 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

KCNJ3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	154,698,695 - 154,858,354 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	154,697,855 - 154,858,354 (+)	Ensembl			hg38	GRCh38
GRCh37	2	155,555,207 - 155,714,866 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	155,263,339 - 155,421,260 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	155,380,600 - 155,538,522	NCBI
Celera	2	149,169,529 - 149,327,383 (+)	NCBI		Celera
Cytogenetic Map	2	q24.1	NCBI
HuRef	2	147,441,981 - 147,601,674 (+)	NCBI		HuRef
CHM1_1	2	155,561,395 - 155,721,100 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	155,151,671 - 155,311,378 (+)	NCBI		T2T-CHM13v2.0

Kcnj3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	55,301,814 - 55,488,157 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	55,325,982 - 55,488,157 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	55,411,798 - 55,598,145 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	55,435,970 - 55,598,145 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	55,289,567 - 55,447,936 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	55,252,542 - 55,410,911 (+)	NCBI		MGSCv36	mm8
Celera	2	57,211,331 - 57,365,389 (+)	NCBI		Celera
Cytogenetic Map	2	C1.1	NCBI
cM Map	2	31.66	NCBI

Kcnj3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	60,353,990 - 60,518,110 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	60,354,146 - 60,518,104 (+)	Ensembl				GRCr8
mRatBN7.2	3	39,944,896 - 40,106,646 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	39,945,351 - 40,109,124 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	43,306,813 - 43,466,585 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	51,891,606 - 52,051,367 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	49,676,492 - 49,836,251 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	41,019,898 - 41,181,070 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	41,019,898 - 41,181,070 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	46,103,695 - 46,264,737 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	37,068,672 - 37,256,990 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	38,059,571 - 38,220,833 (+)	NCBI		Celera
RGSC_v3.1	8	70,763,612 - 70,766,543 (+)	NCBI
RH 3.4 Map	3	507.0	RGD
Cytogenetic Map	3	q21	NCBI

Kcnj3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955440	19,716,081 - 19,833,437 (+)	Ensembl
ChiLan1.0	NW_004955440	19,716,081 - 19,836,957 (+)	NCBI	ChiLan1.0	ChiLan1.0

KCNJ3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	57,366,681 - 57,525,646 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	57,381,657 - 57,540,624 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	41,965,152 - 42,124,285 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	159,214,030 - 159,370,956 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2

Kcnj3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	118,314,441 - 118,454,663 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936469	23,165,707 - 23,302,830 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936469	23,163,057 - 23,304,178 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KCNJ3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	62,264,069 - 62,413,566 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	62,263,913 - 62,415,915 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	69,329,216 - 69,481,280 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KCNJ3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	40,096,042 - 40,258,641 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	40,096,527 - 40,255,646 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	159,286,264 - 159,444,061 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kcnj3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624732	11,132,024 - 11,278,026 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624732	11,128,474 - 11,278,528 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Kcnj3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	33,053,421 - 33,214,383 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in KCNJ3
1571 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	21	15	5	6	5	6	32	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005640188	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038446759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038446760	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038446761	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038463397	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038520859	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038520860	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038520862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038584529	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038584530	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038584531	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038648947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038648948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038648949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_545477	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002623309	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000197	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000014603 ⟹ ENSCAFP00000013508

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	36	1,354,678 - 1,493,766 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000078992 ⟹ ENSCAFP00000060737

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	36	1,354,678 - 1,365,539 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000082892 ⟹ ENSCAFP00000064169

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	36	1,354,678 - 1,492,681 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845044189 ⟹ ENSCAFP00845034629

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	36	1,366,153 - 1,505,563 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845044268 ⟹ ENSCAFP00845034690

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	36	1,366,328 - 1,507,279 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845044304 ⟹ ENSCAFP00845034717

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	36	1,366,328 - 1,367,410 (+)	Ensembl

RefSeq Acc Id:

XM_005640188 ⟹ XP_005640245

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	36	1,354,686 - 1,492,797 (+)	NCBI
Dog10K_Boxer_Tasha	36	1,385,232 - 1,522,971 (+)	NCBI

Sequence:

show sequence

GCGCTCGGACTCTGGCTCGCCCCTCCGTATTATGTCTGCACTCCGAAGGAAATTTGGGGACGAC
TACCAGGTAGTGACCACCTCGTCCAGCGGCGCGGGCTTGCAGCCCCAGGGGCCGGGCCCGGGCC
CGCAGCAGCAGCTTGTGCCCAAGAAGAAGCGGCAGCGGTTCGTGGACAAGAACGGCCGGTGCAA
TGTGCAGCACGGCAACCTGGGCAGCGAGACGAGCCGCTACCTGTCGGACCTCTTCACCACGCTG
GTGGACCTCAAGTGGCGCTGGAACCTCTTCATCTTCATCCTCACCTACACCGTGGCCTGGCTCT
TCATGGCGTCCATGTGGTGGGTGATCGCCTACACCCGGGGCGACCTGAACAAAGCCCACGTCGG
CAACTACACGCCCTGCGTGGCCAATGTCTACAACTTCCCGTCCGCCTTCCTCTTCTTCATCGAG
ACCGAGGCCACCATCGGCTACGGCTACCGCTACATCACCGACAAGTGCCCCGAGGGCATCATCC
TCTTCCTCTTCCAGTCCATCCTGGGCTCCATCGTGGACGCCTTCCTCATCGGCTGCATGTTCAT
CAAGATGTCCCAGCCCAAGAAGCGCGCCGAGACCCTGATGTTCAGCGAGCACGCGGTCATCTCC
ATGAGGGACGGGAAGCTCACGCTCATGTTCCGGGTGGGCAACCTGCGCAACAGCCACATGGTGT
CGGCGCAGATCCGCTGCAAGCTGCTCAAGGGATGACTTGTCAAGCTCGAACATCTTACACTGAA
GATGAAGTTCTTTGGGGTCATCGTTTTTTTCCTGTTATCTCCTTAGAAGAAGGGTTCTTTAAAG
TTGATTACTCCCAATTCCACGCG

hide sequence

RefSeq Acc Id:

XM_038446759 ⟹ XP_038302687

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	36	1,366,233 - 1,507,708 (+)	NCBI

RefSeq Acc Id:

XM_038446760 ⟹ XP_038302688

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	36	1,366,227 - 1,369,689 (+)	NCBI

RefSeq Acc Id:

XM_038446761 ⟹ XP_038302689

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	36	1,366,227 - 1,504,110 (+)	NCBI

RefSeq Acc Id:

XM_038463397 ⟹ XP_038319325

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	36	1,385,232 - 1,388,708 (+)	NCBI

RefSeq Acc Id:

XM_038520859 ⟹ XP_038376787

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	36	1,374,467 - 1,515,573 (+)	NCBI

RefSeq Acc Id:

XM_038520860 ⟹ XP_038376788

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	36	1,374,461 - 1,377,933 (+)	NCBI

RefSeq Acc Id:

XM_038520862 ⟹ XP_038376790

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	36	1,374,461 - 1,511,975 (+)	NCBI

RefSeq Acc Id:

XM_038584529 ⟹ XP_038440457

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	36	1,478,637 - 1,620,408 (+)	NCBI

RefSeq Acc Id:

XM_038584530 ⟹ XP_038440458

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	36	1,478,631 - 1,482,111 (+)	NCBI

RefSeq Acc Id:

XM_038584531 ⟹ XP_038440459

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	36	1,478,631 - 1,616,806 (+)	NCBI

RefSeq Acc Id:

XM_038648947 ⟹ XP_038504875

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	36	1,435,406 - 1,577,189 (+)	NCBI

RefSeq Acc Id:

XM_038648948 ⟹ XP_038504876

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	36	1,435,400 - 1,438,868 (+)	NCBI

RefSeq Acc Id:

XM_038648949 ⟹ XP_038504877

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	36	1,435,400 - 1,573,589 (+)	NCBI

RefSeq Acc Id:

XM_545477 ⟹ XP_545477

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	36	1,354,686 - 1,496,397 (+)	NCBI
Dog10K_Boxer_Tasha	36	1,385,238 - 1,526,573 (+)	NCBI

Sequence:

show sequence

GCGCTCGGACTCTGGCTCGCCCCTCCGTATTATGTCTGCACTCCGAAGGAAATTTGGGGACGAC
TACCAGGTAGTGACCACCTCGTCCAGCGGCGCGGGCTTGCAGCCCCAGGGGCCGGGCCCGGGCC
CGCAGCAGCAGCTTGTGCCCAAGAAGAAGCGGCAGCGGTTCGTGGACAAGAACGGCCGGTGCAA
TGTGCAGCACGGCAACCTGGGCAGCGAGACGAGCCGCTACCTGTCGGACCTCTTCACCACGCTG
GTGGACCTCAAGTGGCGCTGGAACCTCTTCATCTTCATCCTCACCTACACCGTGGCCTGGCTCT
TCATGGCGTCCATGTGGTGGGTGATCGCCTACACCCGGGGCGACCTGAACAAAGCCCACGTCGG
CAACTACACGCCCTGCGTGGCCAATGTCTACAACTTCCCGTCCGCCTTCCTCTTCTTCATCGAG
ACCGAGGCCACCATCGGCTACGGCTACCGCTACATCACCGACAAGTGCCCCGAGGGCATCATCC
TCTTCCTCTTCCAGTCCATCCTGGGCTCCATCGTGGACGCCTTCCTCATCGGCTGCATGTTCAT
CAAGATGTCCCAGCCCAAGAAGCGCGCCGAGACCCTGATGTTCAGCGAGCACGCGGTCATCTCC
ATGAGGGACGGGAAGCTCACGCTCATGTTCCGGGTGGGCAACCTGCGCAACAGCCACATGGTGT
CGGCGCAGATCCGCTGCAAGCTGCTCAAGTCTCGGCAGACACCTGAGGGTGAGTTCCTTCCCCT
TGACCAGCTTGAACTGGATGTAGGTTTTAGTACAGGGGCAGATCAACTTTTTCTTGTTTCCCCC
CTCACAATTTGCCACGTGATCGATGCCAAAAGCCCCTTTTATGACCTATCCCAGCGAAGCATGC
AAACTGAACAGTTCGAGATTGTCGTCATCCTAGAAGGCATTGTGGAAACAACTGGGATGACTTG
TCAAGCTCGAACATCTTACACTGAAGATGAAGTTCTTTGGGGTCATCGTTTTTTTCCTGTTATC
TCCTTAGAAGAAGGGTTCTTTAAAGTTGATTACTCCCAATTCCACGCGACGTTTGAAGTCCCCA
CCCCACCCTATAGTGTGAAAGAACAGGAGGAGATGCTTCTTATGTCGTCCCCTTTAATAGCACC
AGCCATAACTAACAGCAAAGAAAGACATAATTCTGTGGAGTGCTTAGATGGACTGGATGACATT
ACAACAAAACTTCCATCTAAGCTGCAGAAAATTACTGGAAGAGAAGACTTTCCCAAAAAACTCT
TGAGGATGAGTTCTACGACTTCAGAAAAAGCCTACAGCTTGGGAGATTTGCCCATGAAACTTCA
ACGAATAAGTTCGGTTCCAGGCAACTCAGAGGAAAAACTGGTGTCTAAAACCACCAAGATGTTG
TCTGACCCCATGAGCCAGTCAGTGGCTGATTTGCCACCAAAGCTTCAAAAGATGGCTGGAGGAG
CAGCCAGGATGGAAGGGAATCTCCCAGCCAAACTACGAAAAATGAACTCTGATCGATTCACATA
ACAAAACACCCCCGTAGGCATTATTTACTGTTTGAATTAGTAATAGTCCAATATTTGGCTGATG
AGGTAATCCTCGAAGGAATCTGAAAGGCACATTTTTCTCCCCAGTCACATATGCATATTTGAGA
ACCCTTTCTTCCCAAGTATTGCCACTGTGCAGAAAGCAAAGTTGTGTAAAGGGAGGACATCGTA
AGAAAGTTCTTATTAACGGGCATGTATTATCACATCAAGCATGCAATAATGTGCAAATTTTGCA
TTTAGTTTTATGGCATGATTTATATATGGTATATTTATATTGTATATTCTGGAAAAAATATATA
TATATATTTAAAGAGGTGGTACTCTTCACGACATTTCTAACATATGTATTAAGCCAAACATGAG
TGGATAGCTTTCAGGGCGATAAAAACTATATATATGTGTGTGTGTGTGTGTATATGTATATGTA
TACACACACACACACACACATACATATATATCTAATAAAATTGTGATGTTTTGTTCAAAGTTGT
AGTTCTTGTGCATGTTTACTTTATTAGGCTAGGAAGGCTTCTGGCATTAATTATTAATACCAAA
TATTTTAGCCTTAAATTATTTGTCATTTTAAAATTTGATTTAATGTTTTCTGCTGTTTAAGGTC
CTGGGAGGTTATCAATTGTACTTTATATGAGGGAGTCACTTGAGTCTATGCTACTTATGGCCCT
ACATAAATATAACCATCATGTATTTAACTTGTAAATTGTAGAGCATACCAGTATGCTAAAAATT
TCTTACAATTTTTAAAAGTTGCTAGTACTAGGTGAAAATTAGTTAATTTGAGAATTGGTCCTTT
TCTGGACAACTTGAAGCCTGGAAATCTGTTTTGTATATGATCTAATACAAACATGAGCTCTGAA
CAAATGCTGAATCATTGTAGCCATCAGTAGCCAACTTACTTTGAATATATCAGAATCTGCTTGA
AATTACATGATTAATGGTCCCTGTTTCAAACAGTCAGTTGGTAGCATTTCCACCCTTTTTCTGG
AATTTCTGTCATTTTAAAAACCAATAATTTATTCTTGAGGAGATACAACAATACAATGAAACAG
ATGATAAATATTTATGCTTAAAATACGTATGTCTAAATGAGTCTCTTTTTTAATGCTGTTCTCT
TGTTTGTAGCACTTATTGTATCAGGACAGACTTTTTTCTGCACCTGGGGAAACTATCCCACCCA
TGCCTGTCACTCTGTTCAGGAAGAATGTTATGTATATACCCGAGAGAATTTTAAATTAGATGAA
TTGAAGATATTTTACCCATGTGGGCTTGTTTGTTTGTTTGTTTGGTAACCATGATTTTATTGGT
GTCCTGGATCCCTGGCCTACCAAAGTAATTTTAGCAGTACTATTTTTCTAACCCCGAGGTCTGA
TATTTATTACTCATTAGTGGAAATAAAAACTATTGCTCAGAAGAACACCTATGAAATAGAGATC
TGGAATGCAGAGACTTTTATGAAATTTTTTAAGTGTTCCTTATCAAAATACCATGGATTTTCCT
ATAAAATTTCTTTGGGCATTGCACTGTAAGTCTGTTCAGAATTAAGCTATTTCCCCTTGTTAAT
ATCAAAATCCTTACTTATCCTTAATGACTGGTTTGGGCTCTCATCATTTCCCATTTTTTAGCAA
TCCTGTGATGATTTTCTTATTGGAAAATAATTACATCAACAATTCTGTCATTAACTACAATAAT
ACCGTCTGGCTACCTCTGTATCAACCAAATTCTGTAGGTGCAAACATATCCCAGGGAATTGTTA
CTGGCAAAATGATCAACCTTGAGCATTCATCCACTGTGAATAGAGTTAGCTGCTCTACCCCTTG
ATCCCATGGCTGGTTATAGGAAATGAAATAGTAACAGAGAGAGAAAGGGGTCCAAGGGGCATGA
GATATTTCTTATCAGTGGAAGAAACTCCATAGATCATTTAGTCCAAACACTTAAAACTAAATAG
AGCCATAATTTAATTTGGAGAGTCGTTCTAATTTGTCTTTGGTACCAAGGAGACTATGGGACCA
AAGACAAACTCTCCGAATGTATTCACTCATTCATTCAACAAAAATTTTTGCATGCCTTTCATGT
CCTAGGTAGTTTTAGCTCCTGGAAATTTGGCTACAACTAAGTTAGAGGAGGTCGCTGCCCATTT
GAACATTGCATATTGGTAGGAGAGTGGAGAGGTGCCCTGTGGGGACAGAACACAAATGAGATGA
TTTCAGATACTCAAAATATCAGTTTAAGGTGAAGAAAACAGGACAGCAAAATGGAAAAATGACT
GGGTGGAATAAGAATTGACTATTTTAGAAGAGGTGACTGGCTTAGGGAGGAAGAGATACATGAA
CAGAGGTCTGAATAATGAGAAAGAAACACTATTGCCAAAATTAATTTTTCTTAATGATGCTATT
CCTTTATCTTTTCCACATATGTATGGGAAAGGTATGATTTCTGCATGTAATTGCAGGTTAGCCC
GTATTGCTAAGTTGATCAGAGGTCCCAGTTTACCCAGGGGAGTTCCAGTTTATACCTGTCGTAC
CTGTGTAATTAATAATAGCACTCCCTTCACTCTTAGAATGTCCTGGTTTGGATGATACATTATA
TGGTGACTCTATGTTTTTGTTGAAACTAAATTATGAAGTCTGATATATTTGGATAAAAATAAAG
AATTGCTTTTTCTTCTCTTTTTGCTGATTTTTTTTTGACACTGATCATTACAAGAAAGATCATC
TCCGTTTCATATATTTCAGCCTGCAGGACTTCTTATCAAAGTGATTTCATGTAACATTTGTTCA
ATCTGTATATGACATGTTTTCTCAGCAGTGAAAAGTTATGCATTTTATTGACTGAATAAAACAT
AAACCTCTGGTATTTCCATTTCAGGAAGTTATAAGAGCTCAAATCAAAGAGAATAAAAGTCAAC
TGAAGCCAGGATAATTGTCAGCCCACCAATGTGGTGACTGTTGGAAAGCAAAATGTAATGTTGT
TCACTGAACTGAATAATTCTACTTAACAACTAGAAACTAGTCCCTTTCATGGTATAGCTCCTGT
CATGGTAAAATATTTCATTCTATTTATCAAAATGATGTGAATAAAAGAGATATGATTATTTTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005640245	(Get FASTA)	NCBI Sequence Viewer
	XP_038302687	(Get FASTA)	NCBI Sequence Viewer
	XP_038302688	(Get FASTA)	NCBI Sequence Viewer
	XP_038302689	(Get FASTA)	NCBI Sequence Viewer
	XP_038319325	(Get FASTA)	NCBI Sequence Viewer
	XP_038376787	(Get FASTA)	NCBI Sequence Viewer
	XP_038376788	(Get FASTA)	NCBI Sequence Viewer
	XP_038376790	(Get FASTA)	NCBI Sequence Viewer
	XP_038440457	(Get FASTA)	NCBI Sequence Viewer
	XP_038440458	(Get FASTA)	NCBI Sequence Viewer
	XP_038440459	(Get FASTA)	NCBI Sequence Viewer
	XP_038504875	(Get FASTA)	NCBI Sequence Viewer
	XP_038504876	(Get FASTA)	NCBI Sequence Viewer
	XP_038504877	(Get FASTA)	NCBI Sequence Viewer
	XP_545477	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000013508.4
	ENSCAFP00000060737.2
	ENSCAFP00030012375.1
	ENSCAFP00040020599.1
	ENSCAFP00845034629.1
	ENSCAFP00845034690
	ENSCAFP00845034690.1
	ENSCAFP00845034717.1

RefSeq Acc Id:	XP_545477 ⟸ XM_545477
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0KAN6 (UniProtKB/TrEMBL), A0A8C0SF56 (UniProtKB/TrEMBL), A0A8I3PT84 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSALRRKFGDDYQVVTTSSSGAGLQPQGPGPGPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSET SRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVY NFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAE TLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFS TGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDE VLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKEQEEMLLMSSPLIAPAITNSKERHN SVECLDGLDDITTKLPSKLQKITGREDFPKKLLRMSSTTSEKAYSLGDLPMKLQRISSVPGNSE EKLVSKTTKMLSDPMSQSVADLPPKLQKMAGGAARMEGNLPAKLRKMNSDRFT hide sequence

RefSeq Acc Id:	XP_005640245 ⟸ XM_005640188
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I3S949 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSALRRKFGDDYQVVTTSSSGAGLQPQGPGPGPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSET SRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVY NFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAE TLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKG hide sequence

Ensembl Acc Id:

ENSCAFP00000060737 ⟸ ENSCAFT00000078992

Ensembl Acc Id:

ENSCAFP00000013508 ⟸ ENSCAFT00000014603

Ensembl Acc Id:

ENSCAFP00000064169 ⟸ ENSCAFT00000082892

RefSeq Acc Id:	XP_038376790 ⟸ XM_038520862
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038376788 ⟸ XM_038520860
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038376787 ⟸ XM_038520859
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038504877 ⟸ XM_038648949
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038504876 ⟸ XM_038648948
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038504875 ⟸ XM_038648947
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038302689 ⟸ XM_038446761
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I3S949 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038302688 ⟸ XM_038446760
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3S949 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038302687 ⟸ XM_038446759
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0KAN6 (UniProtKB/TrEMBL), A0A8C0SF56 (UniProtKB/TrEMBL), A0A8I3PT84 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038319325 ⟸ XM_038463397
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3S949 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038440459 ⟸ XM_038584531
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I3S949 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038440458 ⟸ XM_038584530
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3S949 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038440457 ⟸ XM_038584529
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0KAN6 (UniProtKB/TrEMBL), A0A8C0SF56 (UniProtKB/TrEMBL), A0A8I3PT84 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845034629 ⟸ ENSCAFT00845044189

Ensembl Acc Id:

ENSCAFP00845034690 ⟸ ENSCAFT00845044268

Ensembl Acc Id:

ENSCAFP00845034717 ⟸ ENSCAFT00845044304

Protein Domains

Inward rectifier potassium channel C-terminal Potassium channel inwardly rectifying transmembrane

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000009183	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030007731	UniProtKB/TrEMBL
	ENSCAFG00040012864	UniProtKB/TrEMBL
	ENSCAFG00845025035	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000014603.5	UniProtKB/TrEMBL
	ENSCAFT00000078992.2	UniProtKB/TrEMBL
	ENSCAFT00030014186.1	UniProtKB/TrEMBL
	ENSCAFT00040023720.1	UniProtKB/TrEMBL
	ENSCAFT00845044189.1	UniProtKB/TrEMBL
	ENSCAFT00845044268	ENTREZGENE
	ENSCAFT00845044268.1	UniProtKB/TrEMBL
	ENSCAFT00845044304.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.70	UniProtKB/TrEMBL
	2.60.40.1400	UniProtKB/TrEMBL
InterPro	Ig_E-set	UniProtKB/TrEMBL
	IRK_C	UniProtKB/TrEMBL
	K_chnl_inward-rec_Kir	UniProtKB/TrEMBL
	K_chnl_inward-rec_Kir3.1	UniProtKB/TrEMBL
	K_chnl_inward-rec_Kir_cyto	UniProtKB/TrEMBL
	Kir_TM	UniProtKB/TrEMBL
NCBI Gene	KCNJ3	ENTREZGENE
PANTHER	G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 1	UniProtKB/TrEMBL
	PTHR11767	UniProtKB/TrEMBL
Pfam	IRK	UniProtKB/TrEMBL
	IRK_C	UniProtKB/TrEMBL
PRINTS	KIR31CHANNEL	UniProtKB/TrEMBL
	KIRCHANNEL	UniProtKB/TrEMBL
Superfamily-SCOP	SSF81296	UniProtKB/TrEMBL
	Voltage-gated potassium channels	UniProtKB/TrEMBL
UniProt	A0A8C0KAN6	ENTREZGENE
	A0A8C0SF56	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3PJI5_CANLF	UniProtKB/TrEMBL
	A0A8I3PT84	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3S949	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0SE55_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:42264	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-08-06	KCNJ3	potassium inwardly rectifying channel subfamily J member 3	KCNJ3	potassium voltage-gated channel subfamily J member 3	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - SMPDB