Gene: Scn7a (sodium voltage-gated channel alpha subunit 7) Rattus norvegicus
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Symbol: Scn7a
Name: sodium voltage-gated channel alpha subunit 7
Description: ENCODES a protein that exhibits sodium channel activity (ortholog); INVOLVED IN response to bacterium (ortholog); sodium ion homeostasis (ortholog); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN glial cell projection (ortholog); plasma membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol
AGR Description: Predicted to have voltage-gated sodium channel activity; predicted to be involved in several processes, including membrane depolarization during action potential, neuronal action potential, and response to bacterium; predicted to localize to the axon, glial cell projection, and voltage-gated sodium channel complex; orthologous to human SCN7A (sodium voltage-gated channel alpha subunit 7).
Merged Description: Predicted to have voltage-gated sodium channel activity; predicted to be involved in several processes, including membrane depolarization during action potential, neuronal action potential, and response to bacterium; predicted to localize to the axon, glial cell projection, and voltage-gated sodium channel complex; orthologous to human SCN7A (sodium voltage-gated channel alpha subunit 7); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Na-G; Scn6a; sodium channel protein type 7 subunit alpha; sodium channel voltage-gated type VI alpha polypeptide; sodium channel, voltage-gated, type 6, alpha polypeptide; sodium channel, voltage-gated, type VI, alpha polypeptide ; sodium channel, voltage-gated, type VII, alpha; sodium channel, voltage-gated, type VII, alpha subunit
Orthologs:
Homo sapiens (human) : SCN7A (sodium voltage-gated channel alpha subunit 7)  HGNC  Alliance
Mus musculus (house mouse) : Scn7a (sodium channel, voltage-gated, type VII, alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scn7a (sodium voltage-gated channel alpha subunit 7)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN7A (sodium voltage-gated channel alpha subunit 7)
Canis lupus familiaris (dog) : SCN7A (sodium voltage-gated channel alpha subunit 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn7a (sodium voltage-gated channel alpha subunit 7)
Sus scrofa (pig) : SCN7A (sodium voltage-gated channel alpha subunit 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0352,775,779 - 52,877,365 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0359,395,313 - 59,496,997 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4348,633,302 - 48,710,734 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1348,529,673 - 48,607,100 (-)NCBI
Celera350,919,278 - 50,994,687 (-)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Scn7a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61922
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.