Bp140 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp140 (Blood pressure QTL 140) Rattus norvegicus

Symbol: Bp140
Name: Blood pressure QTL 140
RGD ID: 634306
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: 3.3
P Value: 0.0013
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2317,374,703 - 35,528,639RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0313,126,914 - 36,600,143RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0318,456,092 - 41,714,034RGDRnor5.0
RGSC_v3.4316,185,366 - 32,056,774RGDRGSC3.4
RGSC_v3.1316,081,734 - 31,953,146RGD
Cross Type: intercross
Strains Crossed: WKY/Snk SHR/Snk 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Kynu is a candidate Gene for Bp140

Disease Annotations     Click to see Annotation Detail View
hypertension  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
SHR/Snk  (IEA)
WKY/Snk  (IEA)

References

References - curated
1. Mizutan K, etal., Hypertens Res 2002 Jan;25(1):135-40.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
11425803LOC108350352uncharacterized LOC10835035231737963817415805Rat
1307198Pbx3PBX homeobox 331748869117682412Rat
9255683LOC103691768uncharacterized LOC10369176831762428617653427Rat
11375987LOC108350353uncharacterized LOC10835035331771249617715730Rat
1305363Mapkap1MAPK associated protein 131771581317918387Rat
6490845LOC10091175340S ribosomal protein S7-like31774510017745785Rat
1307479Gapvd1GTPase activating protein and VPS9 domains 131796834518041888Rat
2843Hspa5heat shock protein family A (Hsp70) member 531805550718059969Rat
1310612RabepkRab9 effector protein with kelch motifs31806129918083191Rat
41067461LOC120101527uncharacterized LOC12010152731808304118088151Rat
1310460Fbxw2F-box and WD repeat domain containing 231808885918114387Rat
9424697B3galt9beta-1,3-galactosyltransferase 931812086118124642Rat
1308434Psmd5proteasome 26S subunit, non-ATPase 531813371518151000Rat
1564854RGD1564854similar to divalent cation tolerant protein CUTA31815421918174957Rat
1310390Phf19PHD finger protein 1931817528118197289Rat
41148686LOC120101971U6 spliceosomal RNA31819866018198758Rat
7703143LOC102550940uncharacterized LOC10255094031820991118218526Rat
1596290Traf1TNF receptor-associated factor 131822202418242163Rat
2237C5complement C531827069618361994Rat
9094692LOC103691771uncharacterized LOC10369177131838505718387293Rat
1308742RGD1308742similar to Complement C5 precursor31840171618420064Rat
1305317Cntrlcentriolin31842814718500362Rat
620881Rab14RAB14, member RAS oncogene family31850195318523253Rat
7626419LOC102554040uncharacterized LOC10255404031854880318551679Rat
1303089Gsngelsolin31858516618638404Rat
1305109Stomstomatin31864505818667343Rat
11415833LOC10835035540S ribosomal protein S29 pseudogene31865282818653581Rat
1565200Ggta1l1glycoprotein, alpha-galactosyltransferase 1-like 131868471818701674Rat
7519388LOC102548933uncharacterized LOC10254893331868483718704251Rat
41302246LOC120101528spermidine synthase-like31870954818710782Rat
1560029LOC502618ABO-family member 631871144718729488Rat
629476Ggta1glycoprotein alpha-galactosyltransferase 131873298518824916Rat
41223777LOC120101529uncharacterized LOC12010152931880970818826377Rat
41235057LOC120101530uncharacterized LOC12010153031883080318840164Rat
7519941LOC102549213uncharacterized LOC10254921331885924518864078Rat
41334896LOC120101531uncharacterized LOC12010153131885969018860308Rat
40939483LOC120101532uncharacterized LOC12010153231886873618875078Rat
1564343RGD1564343similar to 40S ribosomal protein S1631889902818899541Rat
41255400LOC120101533uncharacterized LOC12010153331890657418915565Rat
621686Dab2ipDAB2 interacting protein31891529019086282Rat
1588742Ttll11tubulin tyrosine ligase like1131910989119335077Rat
41317518LOC120101534uncharacterized LOC12010153431924467019265072Rat
11412302LOC108350358uncharacterized LOC10835035831936841019371814Rat
40930499LOC120101535uncharacterized LOC12010153531937116119375704Rat
1306283Ndufa8NADH:ubiquinone oxidoreductase subunit A831938606319402093Rat
1307739Morn5MORN repeat containing 531940180119429956Rat
1306174Lhx6LIM homeobox 631943243919456268Rat
1307411Rbm18RNA binding motif protein 1831946733319487171Rat
1305897Mrrfmitochondrial ribosome recycling factor31948712419543911Rat
41328151LOC120101536uncharacterized LOC12010153631956929119569873Rat
3439Ptgs1prostaglandin-endoperoxide synthase 131958401519605589Rat
1561766RGD1561766similar to basic transcription factor 331962091619621457Rat
1332877Olr393-psolfactory receptor pseudogene 39331964110519641968Rat
1334061Olr394-psolfactory receptor pseudogene 39431966717919668113Rat
1332916Olr395olfactory receptor 39531971224219713180Rat
1333442Olr396olfactory receptor 39631976523019766168Rat
1589699Klf5-ps1Kruppel-like factor 5, pseudogene 131978734019790302Rat
1334157Olr397olfactory receptor 39731980352919806493Rat
1333097Olr398olfactory receptor 39831983877119839700Rat
1333418Olr399olfactory receptor 39931987183619872759Rat
1333084Olr400olfactory receptor 40031991073819911667Rat
1333467Olr401olfactory receptor 40131994606319947001Rat
1333900Olr402olfactory receptor 40232004046220041400Rat
1332955Olr403olfactory receptor 40332006734920068272Rat
1334217Olr404olfactory receptor 40432014515820146096Rat
1334184Olr405-psolfactory receptor pseudogene 40532019140520192325Rat
1333812Olr406olfactory receptor 40632021130520212240Rat
1332629Olr407olfactory receptor 40732026967820270616Rat
1333536Olr408olfactory receptor 40832031516220316100Rat
1333882Olr409olfactory receptor 40932033968420340625Rat
1333914Olr410olfactory receptor 41032034653520352728Rat
1332682Olr411olfactory receptor 41132038357720384518Rat
1333868Olr412-psolfactory receptor pseudogene 41232039800520398768Rat
1333082Olr413olfactory receptor 41332040964120410579Rat
621629Olr414olfactory receptor 41432041326220414197Rat
1333209Olr415olfactory receptor 41532042412520425072Rat
1334305Olr416olfactory receptor 41632044460420445539Rat
1333103Olr417olfactory receptor 41732045646420457417Rat
1333496Olr418olfactory receptor 41832047236220473294Rat
1334437Olr419olfactory receptor 41932048392120484868Rat
41347654LOC120102126U4 spliceosomal RNA32050396520504098Rat
1333656Olr420olfactory receptor 42032050699520507921Rat
1333411Olr421olfactory receptor 42132051768220518674Rat
1332758Olr422olfactory receptor 42232055178820552741Rat
1334389Olr423olfactory receptor 42332060688720607873Rat
1333742Olr424olfactory receptor 42432062253120623523Rat
1333333Olr425olfactory receptor 42532063997620640929Rat
1332825Olr427olfactory receptor 42732069926620700189Rat
1332944Olr428olfactory receptor 42832076712920768064Rat
1333332Olr429olfactory receptor 42932078454520785474Rat
41129592LOC120101432olfactory receptor 1G1-like32080765020808705Rat
1334355Olr431-psolfactory receptor pseudogene 43132081191620812126Rat
1584028LOC690140similar to olfactory receptor Olr137432083661620837548Rat
1332729Olr433-psolfactory receptor pseudogene 43332084156320841791Rat
1333139Olr434olfactory receptor 43432086229720863280Rat
1584015LOC690155similar to phosducin-like32087269120881151Rat
1589698LOC366027similar to NME1-NME2 protein32088106320883655Rat
1588379LOC502623similar to Ribosome biogenesis regulatory protein homolog32093932120942374Rat
41003160LOC120101898elongin-B-like32098648820987742Rat
41209010LOC120101896elongin-B-like32099050420992516Rat
1582869LOC690241similar to transcription elongation factor B (SIII), polypeptide 232099505620995790Rat
41200826LOC120101897elongin-B-like32099870320999415Rat
41266536LOC120101893elongin-B-like32100233621003559Rat
1590958LOC690876similar to transcription elongation factor B (SIII), polypeptide 232100647021007502Rat
1588382LOC502620similar to transcription elongation factor B (SIII), polypeptide 232101726421018340Rat
41101549LOC120101894elongin-B-like32102182521022305Rat
40987625LOC120101899elongin-B-like32102519421026182Rat
41185658LOC120101895elongin-B-like32102914221030159Rat
6493667LOC100911251disks large homolog 5-like32106224721072153Rat
1591934Klf5-ps2Kruppel-like factor 5, pseudogene 232107191521073656Rat
1582840LOC690273hypothetical protein LOC69027332108898921090611Rat
11420073LOC108350364uncharacterized LOC10835036432109127421095976Rat
41001645LOC120101901uncharacterized LOC12010190132109599121099779Rat
621135Pdcl1phosducin-like 132111016521119763Rat
7654995LOC102556236nucleoside diphosphate kinase B-like32111942321122807Rat
1304833Rc3h2ring finger and CCCH-type domains 232112153121186711Rat
41133334Snord90small nucleolar RNA, C/D box 9032116296821163078Rat
41083260LOC120101486uncharacterized LOC12010148632118503821192945Rat
1306007Zbtb6zinc finger and BTB domain containing 632118916021207561Rat
1308561Zbtb26zinc finger and BTB domain containing 2632119531921207925Rat
11425388LOC108350365uncharacterized LOC10835036532119941021205009Rat
1304691Rabgap1RAB GTPase activating protein 132120801221326013Rat
41011374LOC120101900uncharacterized LOC12010190032124488021283629Rat
1586383Gpr21G protein-coupled receptor 2132127500721279008Rat
620673Strbpspermatid perinuclear RNA binding protein32132831021467753Rat
41374491LOC120102124U4 spliceosomal RNA32142035421420481Rat
1561137RGD1561137similar to 40S ribosomal protein S1632149415521494684Rat
41026169LOC120101537uncharacterized LOC12010153732152771321534482Rat
41016805LOC120101903uncharacterized LOC12010190332154038321543108Rat
1309368Crb2crumbs cell polarity complex component 232154213821564876Rat
41337030LOC120101933U6 spliceosomal RNA32155103821551144Rat
40941630LOC120101945U6 spliceosomal RNA32155175421551860Rat
1307927Dennd1aDENN domain containing 1A32156474922052057Rat
41195976LOC120101902uncharacterized LOC12010190232186943921878730Rat
71076Lhx2LIM homeobox 232211361922143909Rat
11473570LOC108350366uncharacterized LOC10835036632221469422257038Rat
40939602LOC120101538uncharacterized LOC12010153832224525122257178Rat
727779Nek6NIMA-related kinase 632228426922356302Rat
621093Psmb7proteasome 20S subunit beta 732235777722417748Rat
1596103LOC690401hypothetical protein LOC69040132242836922429945Rat
2318734LOC100362149ribosomal protein S20-like32243024722430764Rat
68350Nr5a1nuclear receptor subfamily 5, group A, member 132246478622486328Rat
1564740Nr6a1nuclear receptor subfamily 6, group A, member 132249510922683132Rat
7623233LOC102554311uncharacterized LOC10255431132258587022613734Rat
2325335Mir181a2microRNA 181a-232261584522615961Rat
2325454Mir181b2microRNA 181b-232261694822617035Rat
41296457LOC120101539uncharacterized LOC12010153932261895022632367Rat
1311651Olfml2aolfactomedin-like 2A32268856222717745Rat
7749459LOC102554600uncharacterized LOC10255460032271624422731175Rat
41157828LOC120102092small nucleolar RNA SNORA7932273807222738216Rat
1562587Wdr38WD repeat domain 3832275014522753441Rat
1303007Rpl35ribosomal protein L3532275325522756217Rat
1308867Arpc5lactin related protein 2/3 complex, subunit 5-like32275871022767520Rat
1311305Golga1golgin A132276569022812637Rat
7707315LOC102546322COPII coat assembly protein sec16-like32281271922819111Rat
1594720Scaisuppressor of cancer cell invasion32281328322925364Rat
708460Ppp6cprotein phosphatase 6, catalytic subunit32292981622962123Rat
1589697LOC366036hypothetical LOC36603632303352923034161Rat
41241606LOC120102026small nucleolar RNA SNORA4832304743523047574Rat
7741314LOC102546443NEDD4-binding protein 1-like32315047223151651Rat
1589739LOC362126similar to Voltage-dependent anion-selective channel protein 2 (VDAC-2) (mVDAC2) (mVDAC6) (Outer mitochondrial membrane protein porin 2)32321552623222603Rat
41199927LOC120101540WW domain-binding protein 1-like32350067223506356Rat
2323145LOC100363399hypothetical LOC10036339932360318123604872Rat
41256826LOC120101994U7 small nuclear RNA32362397123624033Rat
40992520LOC120101997U7 small nuclear RNA32362404923624108Rat
9093487LOC10369180540S ribosomal protein S14 pseudogene32371140923711911Rat
41337682LOC120102038small nucleolar RNA SNORA4832392516823925311Rat
2318320LOC10036236640S ribosomal protein S17-like32401982024020305Rat
11496785LOC10835055160S ribosomal protein L12 pseudogene32424981424250522Rat
41069797LOC120102003small nucleolar RNA SNORA7032455500324555138Rat
1561736RGD1561736similar to ribosomal protein L1032455508024555585Rat
1306160Lrp1bLDL receptor related protein 1B32459430226715037Rat
41034676LOC120101904actin, cytoplasmic 2-like32528326925290132Rat
41092566LOC120101541uncharacterized LOC12010154132689036826909301Rat
41393928LOC120102048small nucleolar RNA SNORA1732689649926896629Rat
41001697LOC12010148760S ribosomal protein L7a-like32713001727164425Rat
41260220LOC120101542MLV-related proviral Env polyprotein-like32733382827335839Rat
1593416LOC690655similar to High mobility group protein 1 (HMG-1) (High mobility group protein B1) (Amphoterin) (Heparin-binding protein p30)32766516727706078Rat
71061Kynukynureninase32777864627929470Rat
1359304Arhgap15Rho GTPase activating protein 1532798936828592722Rat
41176684LOC120102081small nucleolar RNA SNORA4032830634528306467Rat
41066404LOC120102110U2 spliceosomal RNA32855995628560093Rat
41126396LOC120101905uncharacterized LOC12010190532856536028568221Rat
1563393Gtdc1glycosyltransferase-like domain containing 132876666629064305Rat
41134582LOC12010154360S ribosomal protein L7a-like32880553128806969Rat
41007407LOC120102113U2 spliceosomal RNA32881327728813416Rat
11498418LOC108350367uncharacterized LOC10835036732887037328882513Rat
41165056LOC120101544uncharacterized LOC12010154432897037628991302Rat
1307272Zeb2zinc finger E-box binding homeobox 232921976529342094Rat
9273023Zeb2-as1ZEB2 antisense RNA 132934307829345943Rat
7498952LOC102548671uncharacterized LOC10254867132943454929491656Rat
9075793LOC103690391uncharacterized LOC10369039132957970029583753Rat
11373432LOC108350369uncharacterized LOC10835036932962628029676672Rat
41353600LOC120101545uncharacterized LOC12010154532974202229786773Rat
7622113LOC102548934uncharacterized LOC10254893432999381829998722Rat
41041303LOC120102076small nucleolar RNA SNORA1733052038230520498Rat
2322483LOC100360268hypothetical LOC10036026833076880130770318Rat
41087157LOC120102072small nucleolar RNA SNORA1733081550330815603Rat
2323086LOC100359959DEAD (Asp-Glu-Ala-Asp) box polypeptide 1833120713731210520Rat
11429489LOC108350370uncharacterized LOC10835037033121664431228107Rat
9265290LOC103691783transcription elongation factor B polypeptide 2 pseudogene33125526531255970Rat
41126518LOC120101546uncharacterized LOC12010154633134491731365067Rat
41040480LOC120102009small nucleolar RNA SNORA433136654831366647Rat
11383937LOC108350593uncharacterized LOC10835059333136701831374155Rat
41010118LOC120101488glyceraldehyde-3-phosphate dehydrogenase-like33139154631396271Rat
41304536LOC120101992U7 small nuclear RNA33142960831429669Rat
41080470LOC120102080small nucleolar RNA SNORA4033152792831528053Rat
41211519LOC120101433uncharacterized LOC12010143333174359231778599Rat
1590993LOC690840similar to ribosomal protein L3733209113732091463Rat
1334145Olr435-psolfactory receptor pseudogene 43533210782932108276Rat
1589738Max-ps1MYC associated factor X, pseudogene 133252095032521403Rat
7597606LOC102553346R3H domain-containing protein 2-like33264742532683617Rat
40982231LOC12010148960S ribosomal protein L7a-like33276042732761372Rat
11507559LOC108350372uncharacterized LOC10835037233297332732986885Rat
70911Acvr2aactivin A receptor type 2A33320496133292673Rat
735212Orc4origin recognition complex, subunit 433329084433334022Rat
9234849LOC103691784uncharacterized LOC10369178433333319233534008Rat
1562961Mbd5methyl-CpG binding domain protein 533358885433738730Rat
41403109LOC120101490uncharacterized LOC12010149033374321433748338Rat
41358771LOC120101434uncharacterized LOC12010143433378665333790312Rat
11479749LOC108350553uncharacterized LOC10835055333385559633860220Rat
1307271Epc2enhancer of polycomb homolog 233386721933967908Rat
1308539Kif5ckinesin family member 5C33403208234185597Rat
7502848LOC102556679uncharacterized LOC10255667933413506434137136Rat
1562767Lypd6bLY6/PLAUR domain containing 6B33419910134360770Rat
1303202Ns5atp4NS5A (hepatitis C virus) transactivated protein 433446571534466470Rat
1587119Lypd6LY6/PLAUR domain containing 633448722234632887Rat
11444381Trnav-aac2transfer RNA valine (anticodon AAC) 233455988934559961Rat
41239310LOC120101547fatty acid-binding protein 5-like33458594934586393Rat
1587102LOC679581hypothetical protein LOC67958133467336934674656Rat
1303272Mmadhcmetabolism of cobalamin associated D33470864934726554Rat
7691310LOC102555425uncharacterized LOC10255542533472651434736258Rat
41020350LOC120101435centrosomal protein of 19 kDa-like33489813134898840Rat
1565084LOC499796LRRGT0001233510231235150397Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10260D3Rat5216631831145418311610Ratregion
33862D3Mit924733035677330357018Ratregion
34252D3Mgh1914231922714719227279Ratregion
36167D3Rat5012232071409020714212Ratregion
36195D3Rat5115032146466021464822Ratregion
36354D3Mit2222731916237119162581Ratregion
37010D3Rat4916032749462127494778Ratregion
34927D3Rat19017533238565332385832Ratregion
35609D3Rat5315831737470317374883Ratregion
35745D3Rat4813032946323529463355Ratregion
38148D3Rat8217233323078833230976Ratregion
38346D3Rat9819933370334733703538Ratregion
38552D3Rat8022733552842835528639Ratregion
38646D3Rat11720332901749029017683Ratregion
39214D3Rat13120232143858421438758Ratregion
42640D3Rat22921332006830720068533Ratregion
42641D3Rat27821031909133519091551Ratregion
42642D3Rat27617032285809622858240Ratregion
40854D3Rat19223531774916217749521Ratregion
40912D3Rat19124932134384121344079Ratregion
41720D3Rat23020031957096319571155Ratregion
43618D3Got1012131741247617412594Ratregion
43620D3Got1720432213140522131609Ratregion
43622D3Got1424931925981119260057Ratregion
43623D3Got1511931934566519345784Ratregion
43624D3Got1622431966389619664120Ratregion
43625D3Got713531940719319407325Ratregion
43626D3Got817731916237919162556Ratregion
43628D3Got2512933496716834967297Ratregion
43629D3Got2727433540087735401151Ratregion
43630D3Got2421033530572735305935Ratregion
60801D3Wox310033117232031172424Ratregion
60385D3Got17521932419245524192674Ratregion
60386D3Got1829132794445927944750Ratregion
60388D3Got2026032354297723543237Ratregion
60389D3Got2112732775715227757279Ratregion
60390D3Got2213533410549734105633Ratregion
60391D3Got2615133362564633625797Ratregion
60392D3Got2819533298503532985232Ratregion
625799D3Got1322732118841821188642Ratregion
66449D3Mco1623632501365025013911Ratregion
66452D3Mco1819931740031017400510Ratregion
727995D3Chm6125033120619931206451Ratregion
727998D3Chm1122732920940029209628Ratregion
728001D3Chm5829632859654628596842Ratregion
728002D3Chm7621533172899331729208Ratregion
728012D3Chm1522331740644217406665Ratregion
728013D3Chm2519233022278930222981Ratregion
728019D3Chm823033167512931675359Ratregion
728024D3Chm5722332844167328441896Ratregion
728028D3Chm722731760028217600509Ratregion
728036D3Chm6020633142640331426609Ratregion
728038D3Chm619131740552217405713Ratregion
1631692D3Got27425632916276629163022Ratregion
1641120D3Got20517133355159133551747Ratregion
1633093D3Got25914632879347828793621Ratregion
1633400D3Got20615833419786434198024Ratregion
1640570D3Got29619132972021329720404Ratregion
1640611D3Cebr731827815818278369Ratregion
1638355D3Got2049033380161533801705Ratregion
1632473D3Got20312932229065622290785Ratregion
1634531D3Got2729232109399621094088Ratregion
5035781PMC169877P153132360318923603720Ratregion
5036213D2Wsu141e20931805968618059895Ratregion
5036233RH12584824531775201517752260Ratregion
5036601AU04856217332278811222788285Ratregion
5037203RH9816124132926441329264654Ratregion
5035685SHGC-3509214832930226029302408Ratregion
5031330PMC140651P112132248000522480126Ratregion
5026144RH13108122032876672328766942Ratregion
5026146RH13109018031946893819469118Ratregion
5028957RH14296811332120683721206950Ratregion
5028979RH14305228732250470222504984Ratregion
5031846AU04696112932907968629079815Ratregion
5029085RH14346214831835764618357794Ratregion
5029097RH14351228332276767122767954Ratregion
5029389RH14460615231890659718906749Ratregion
5032341AI85286712732276731522767442Ratregion
5032617RH13466621331998404219984255Ratregion
5029909BE09768215431954882919548985Ratregion
5029963BF38826316631806103018061196Ratregion
5030267BE09974315332119540121195554Ratregion
5030273BE10514816431947601819476182Ratregion
5025184RH12733919031938614919386339Ratregion
5033329RH13843715632156459021564746Ratregion
5033341RH13847716132834561128345772Ratregion
5025340RH12794221031864442318644633Ratregion
5028224D2Mit3729931945245419452553Ratregion
5033671RH13968120431815050818150712Ratregion
5028396AI31496722933470881134709040Ratregion
5031023BE12111215132616782126167972Ratregion
5025928RH13023418631960538719605573Ratregion
5031149BE11638815531898651018986665Ratregion
5051170RH13448018833306197333062160Ratregion
5051328AW1076499532276848422768579Ratregion
5054949RH14351913531771658517716720Ratregion
5056443RH14438113132232964922330836Ratregion
5052410C8632212232134157621341698Ratregion
5055813RH14401710931768489017684999Ratregion
5052879RH14232719233470888734709079Ratregion
5052999RH14239619232921492229215115Ratregion
5058278BF38693516232280413522804297Ratregion
5058426BE09600517433416898534169159Ratregion
5050284RH13396720631767253817672744Ratregion
5050556RH13412419032132692821327118Ratregion
5053655RH14277418833418258634182774Ratregion
7193056C8632224032134148621341726Ratregion
5054031RH14299028132922607329226354Ratregion
5052791RH14227516133418515634185317Ratregion
5051330AI85251312232132850821328630Ratregion
5054251RH14311723331823621918236452Ratregion
5044398RH13058019331813380318133996Ratregion
5044176RH13045321631791708617917302Ratregion
5046024RH13151519431832607018326264Ratregion
5044554RH13067019732293717822937375Ratregion
5047582RH13241020532246492922465134Ratregion
5047606RH13242419232281345022813642Ratregion
5045798RH13138518631796961417969800Ratregion
5047750RH13250719131840877918408970Ratregion
5048104RH13271021732936646429366681Ratregion
5048318RH13283420031864514218645339Ratregion
5049802RH13369020131806272718062928Ratregion
5042064RH12921819032292929122929481Ratregion
5047286RH13224019231810742918107621Ratregion
5048408RH13288615031852636918526519Ratregion
5039598RH12779719431873318318733377Ratregion
5040392RH12825718331863818118638364Ratregion
5039714RH12786521332134167921341889Ratregion
5043350RH12997618332292945922929642Ratregion
5040578RH12836420032132567221325872Ratregion
5075148RH13842619032519428725194478Ratregion
5072044RH13543220131924819119248392Ratregion
5075414RH13858019032936000229360192Ratregion
5076176RH13902316432120683821207002Ratregion
5074448RH13802313532939263029392765Ratregion
5074562RH13808813031801663218016762Ratregion
5074814RH13823318832634165826341846Ratregion
5076178RH13902413331960487419605007Ratregion
5077592RH13984519833000215930002357Ratregion
5078406RH14032314431737881017378954Ratregion
5079778RH14119718332933731829337499Ratregion
5077888RH14001818932292929622929485Ratregion
5078826RH14057420033274426332744463Ratregion
5080080RH14137121832235592522356143Ratregion
5078404RH14032214331911030719110452Ratregion
5078450RH14035015631933300619333162Ratregion
5071122RH13489919832262920122629399Ratregion
5078790RH14055319832785986027860058Ratregion
5078870RH14059918132118943621189617Ratregion
5073168RH13727921032087268820872898Ratregion
5073382RH13740421331809822518098438Ratregion
5071264RH13498220731808702018087227Ratregion
5073672RH13757212332922846429228587Ratregion
5072444RH13685319531850985318510048Ratregion
5063460BI30183816132953729429537455Ratregion
5064994BE10886415032116939021169540Ratregion
5065044BE10899015032921613729216287Ratregion
5068044AU04738128333025325630253481Ratregion
5070099RH9447215831805971818059876Ratregion
5069030AU04677124132240318822403429Ratregion
5069148AU04669215731821944818219605Ratregion
5070434AI59152911131791804117918152Ratregion
5070518D2Ertd694e20233396683633967038Ratregion
5069268AU04660824832257916722579243Ratregion
5060500BE11023316231806137218061534Ratregion
5063956BE12031515131810266018102811Ratregion
5060942BE10489915531938463019384785Ratregion
5064320BE11440315931959569519595854Ratregion
5065984BE11640015133497072034970871Ratregion
5061842AW53384018031881100318811183Ratregion
5065382BE11529415033463255134632701Ratregion
5064570BE10812815031912737819127528Ratregion
5061482BE11186121332928368329283896Ratregion
5086865BQ20597417331950578219505955Ratregion
5082151BI28002815231890659718906746Ratregion
5087797D2Wsu17e20531805965818059863Ratregion
5087905Hspa513331805967218059805Ratregion
5089789AU04936419131814751818147709Ratregion
5083031BF39069815131933523819335389Ratregion
5088455AU04858015032224537522245525Ratregion
5081667BE11791915532134748221347637Ratregion
5090291AU04966413631922715719227293Ratregion
5088327AU04850323332802726528027502Ratregion
5080970RH14188821733430757734307794Ratregion
5090517AU04979819831868799918688199Ratregion
5088837AU04879923133314295633143187Ratregion
5085582AA94468916232142287321423035Ratregion
5090187AU04960221232812860828128822Ratregion
5089061AU04893118531851221418512399Ratregion
5082799BF39012815931933621519336374Ratregion
5081126RH14198018732164935121649538Ratregion
5086679BM38737420333329175533291958Ratregion
5085722BQ20338018731843735618437544Ratregion
5507555D11S256910433544740035447504Ratregion
5503222UniSTS:23723717031978843219788601Ratregion
5503591UniSTS:46468411832246607822466196Ratregion
5504145UniSTS:25918016231805617118056705Ratregion
5504044px-43d224632447248124472727Ratregion
5504930Zik112331867235918672482Ratregion
5505598UniSTS:48513094832048392020484868Ratregion
5505694UniSTS:48939595432055178720552741Ratregion
5505937Acvr2a14233320543933205581Ratregion
5506131UniSTS:4984326631861305518613121Ratregion
5506539HSPA5_98879631805908418059880Ratregion
5506260D6S451168932221208922213778Ratregion
5499735UniSTS:23438515632293100022931156Ratregion
5499587At-9B-134114132445043524451577Ratregion
5502082MARC_31635-31636:1045776384:135133328919633289547Ratregion
5499691Acvr2033328208633283655Ratregion
5503122GOLGA1-197632280041922801395Ratregion
5503190ksks38827133328923733289508Ratregion
5500831G0709310731748921117489318Ratregion
5501063PMC133732P146133410682134107282Ratregion
5501746MARC_10305-10306:998934185:198132284629922847280Ratregion
5505540D2S171152732229830222299679Ratregion
5501942MARC_17905-17906:1025019334:1033328802833289310Ratregion
5502567RH12536827331805916418059437Ratregion
Position Markers

Flank 1: (D3Rat53)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2317,374,703 - 17,374,883 (+)MAPPER
Rnor_6.0313,126,914 - 13,127,093NCBI
Rnor_5.0318,456,092 - 18,456,271UniSTS
RH 3.4 Map3139.8RGD
RH 3.4 Map3139.8UniSTS
RH 2.0 Map374.3RGD
SHRSP x BN Map34.6199RGD
FHH x ACI Map36.94RGD
Peak: (Kynu)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2327,778,646 - 27,929,470 (+)NCBI
mRatBN7.2 Ensembl327,778,772 - 27,929,488 (+)Ensembl
Rnor_6.0328,416,926 - 28,566,939 (+)NCBI
Rnor_6.0 Ensembl328,416,954 - 28,566,928 (+)Ensembl
Rnor_5.0333,622,141 - 33,770,793 (+)NCBI
RGSC_v3.4324,046,242 - 24,195,898 (+)NCBI
RGSC_v3.1323,942,613 - 24,092,267 (+)NCBI
Celera326,096,675 - 26,244,576 (+)NCBI
Cytogenetic Map3q12NCBI
Flank 2: (D3Rat80)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2335,528,428 - 35,528,639 (+)MAPPER
Rnor_6.0336,599,933 - 36,600,143NCBI
Rnor_5.0341,713,824 - 41,714,034UniSTS
RGSC_v3.4332,056,564 - 32,056,774UniSTS
RGSC_v3.4332,056,563 - 32,056,774RGD
RGSC_v3.1331,952,935 - 31,953,146RGD
Celera333,686,883 - 33,687,093UniSTS
RH 2.0 Map3188.3RGD
SHRSP x BN Map318.8999RGD
FHH x ACI Map327.9799RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)31077870450302886Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1298073Cm13Cardiac mass QTL 132.5heart mass (VT:0007028)heart wet weight (CMO:0000069)32501391138192233Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33068464275684642Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
2325840Bp345Blood pressure QTL 3450.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31831145428441896Rat
731172Bp151Blood pressure QTL 1510.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31831145447233430Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33370334761017857Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33142640370668733Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
631832Sach1Saccharin preference QTL 12.70.02consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)32749462144188411Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)heart rate (CMO:0000002)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)body weight (CMO:0000012)31737470335528639Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32846857173468571Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
1558657Cm43Cardiac mass QTL 436.60.0000000293heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
2313049Bss72Bone structure and strength QTL 722.60.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)32749462150302886Rat
2313076Bss74Bone structure and strength QTL 7420.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)32749462150302886Rat
2313079Bss73Bone structure and strength QTL 731.5tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)32749462150302886Rat
2313093Bmd77Bone mineral density QTL 772.20.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)32749462150302886Rat
2313101Bmd76Bone mineral density QTL 763.60.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)32749462150302886Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32824968773249687Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32824968773249687Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32824968773249687Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32824968773249687Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)heart rate (CMO:0000002)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)body weight (CMO:0000012)31737470335528639Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
12879849Bw180Body weight QTL 1800.037body mass (VT:0001259)body weight (CMO:0000012)31831145447233430Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
10450806Scl71Serum cholesterol level QTL 715.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32419245527494778Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33142640370668733Rat
12879850Cm91Cardiac mass QTL 910.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)31831145447233430Rat
12879854Kidm63Kidney mass QTL 630.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)31831145447233430Rat
12879851Cm92Cardiac mass QTL 920.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)31831145447233430Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33142640370668733Rat
12879853Am5Aortic mass QTL 50.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)31831145447233430Rat
12879852Cm93Cardiac mass QTL 930.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)31831145447233430Rat
10450811Scl73Serum cholesterol level QTL 734.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32419245527494778Rat
10450808Scl72Serum cholesterol level QTL 724.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32419245527494778Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33142640370668733Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33142640370668733Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33142640370668733Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Bp140

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_gene Kynu mRNA expression was higher in the brainstem in SHR than in WKY 631322
qtl_general associates with increased residuals of systolic blood pressure compared to WKY progenitors 631322
qtl_trait Residuals of diastolic blood pressure (RDBP), measurements of diastolic blood pressure after adjusting for heart rate, body weight and Knyu genotype, were less significant between SHR and WKY genotypes of the Knyu locus (P = 0.0173).  
qtl_trait_method Residuals of systolic blood pressure (RSBP) were measurements of systolic blood pressure after adjusting for heart rate, body weight and Knyu genotype.