Dpp4<sup>DPPIV</sup> (dipeptidylpeptidase 4; DPPIV mutant) - Rat Genome Database

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Gene: Dpp4DPPIV (dipeptidylpeptidase 4; DPPIV mutant) Rattus norvegicus
Symbol: Dpp4DPPIV
Name: dipeptidylpeptidase 4; DPPIV mutant
RGD ID: 12792942
Description: The DPP4 mutant allele was a spontaneous mutation found in Fischer 344 rats, which caused a deficiency in Dpp4. The mutant allele has a G to A change at nucleotide 1897 (in exon 22), which results in an amino acid change of Gly (WT; GGA) to Arg (Mut; AGA).
ASSOCIATED WITH decreased anxiety-related response; decreased circulating adrenocorticotropin level; decreased circulating alanine transaminase level
Type: allele  of Dpp4  
Previously known as: Dpp4DPPIV-; Dpp4DPPIV-
Is Marker For: Strains:   F344-Dpp4DPPIV-/DchcHsdRrrc   DA.F344-Dpp4DPPIV/SvH  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References - curated
# Reference Title Reference Citation
1. Phenotyping of congenic dipeptidyl peptidase 4 (DP4) deficient Dark Agouti (DA) rats suggests involvement of DP4 in neuro-, endocrine, and immune functions. Frerker N, etal., Clin Chem Lab Med. 2009;47(3):275-87. doi: 10.1515/CCLM.2009.064.


Related Rat Strains
The following Strains have been annotated to Dpp4DPPIV



Nucleotide Sequences

Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-09 Dpp4DPPIV  dipeptidylpeptidase 4; DPPIV mutant  Dpp4DPPIV-  dipeptidylpeptidase 4; DPPIV mutant  Symbol changed 629549 APPROVED