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Strain: WKY-Cyp2j4em1Sage/Tja

Symbol: WKY-Cyp2j4em1Sage/Tja
Strain: WKY-Cyp2j4em1Sage
Substrain: Tja
RGD ID: 12904679
Citation ID: RRID:RGD_12904679
Ontology ID: RS:0004589
Alleles: Cyp2j4em1Sage
Previously known as: WKY-Cyp2j4-KO ; Cyp2j4-/-; WKY-Cyp2j4em1Sage /Tja
Type: mutant
Source: Not Available
Origin: ZFN system was used to introduce a 25-bp deletion mutation in the exon 4 of Cyp2j4 gene of WKY/NCrl rat embryos. This deletion results in premature stop of protein translation.
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25111,179,981 - 111,207,490RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.05119,546,458 - 119,564,843RGD_MAPPER_PIPELINERnor6.0
Rnor_5.05119,130,644 - 123,455,814RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.45116,702,370 - 116,729,722RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Macrophage epoxygenase determines a profibrotic transcriptome signature. Behmoaras J, etal., J Immunol. 2015 May 15;194(10):4705-16. doi: 10.4049/jimmunol.1402979. Epub 2015 Apr 3.
2. Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis. Olona A, etal., Mol Metab. 2018 May;11:18-32. doi: 10.1016/j.molmet.2018.03.003. Epub 2018 Mar 9.


Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-03-14 WKY-Cyp2j4em1Sage/Tja    WKY-Cyp2j4em1Sage /Tja    Symbol updated 68687 APPROVED
2018-03-14 WKY-Cyp2j4em1Sage/Tja    WKY-Cyp2j4em1Sage /Tja    Symbol updated 68687 APPROVED