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Gene: Slc6a12 (solute carrier family 6 member 12) Rattus norvegicus
Symbol: Slc6a12
Name: solute carrier family 6 member 12
Description: Predicted to have gamma-aminobutyric acid:sodium symporter activity and neurotransmitter binding activity. Involved in cellular hyperosmotic response; cellular water homeostasis; and response to organic substance. Localizes to integral component of membrane. Orthologous to human SLC6A12 (solute carrier family 6 member 12); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
Also known as: Betaine/GABA transporter 1; BGT1; GABA transporter; GABA transporter 1; Gat1; na(+)/Cl(-) betaine/GABA transporter; RNU28927; sodium- and chloride-dependent betaine transporter; solute carrier family 6 (neurotransmitter transporter), member 12; solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12; vesicular GABA transporter; VGAT
Homo sapiens (human) : SLC6A12 (solute carrier family 6 member 12)  HGNC  Alliance
Mus musculus (house mouse) : Slc6a12 (solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc6a12 (solute carrier family 6 member 12)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC6A12 (solute carrier family 6 member 12)
Canis lupus familiaris (dog) : SLC6A12 (solute carrier family 6 member 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc6a12 (solute carrier family 6 member 12)
Sus scrofa (pig) : SLC6A12 (solute carrier family 6 member 12)
Chlorocebus sabaeus (African green monkey) : SLC6A12 (solute carrier family 6 member 12)
Heterocephalus glaber (naked mole-rat) : Slc6a12 (solute carrier family 6 member 12)
more info ...
Allele / Splice: Slc6a12em1Mcwi  
Genetic Models: SS-Slc6a12em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04153,921,199 - 153,941,333 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4153,921,115 - 153,941,391 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04221,009,224 - 221,029,242 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44157,781,178 - 157,800,038 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14158,026,113 - 158,044,974 (+)NCBI
Celera4143,424,065 - 143,442,410 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc6a12
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620255
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.