Strain Report - Rat Genome Database

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Strain: F344-Slc6a3m1Span

Symbol: F344-Slc6a3m1Span
Strain: F344-Slc6a3m1
Substrain: Span
RGD ID: 126925196
Citation ID: RRID:RGD_126925196
Ontology ID: RS:0004942
Alleles: Slc6a3m1Span
Type: mutant
Source: Central Institute of Mental Health Department of Psychopharmacology Central Institute of Mental Health Mannheim,
Origin: This strain was identified in the N-ethyl-N-nitrosourea (ENU)-driven target-selected mutagenesis screen. A point mutation in the Slc6a3 (DAT) coding sequence (exon 3) with a T/G transversion at nucleotide position 471 was identified in a male rat. This nucleotide exchange leads to substitution of an asparagine amino acid residue by a lysine residue at position 157 (N157K) in the SLC6A3 (DAT) protein, which introduces new positive charge into the amino acid sequence.
Genetic Status: Homozygous
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2129,709,443 - 29,750,413RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0132,323,011 - 32,363,983RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0133,745,060 - 33,788,878RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4130,516,568 - 30,557,540RGD_MAPPER_PIPELINERGSC3.4






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