Strain Report - Rat Genome Database

Name: F344- Slc6a3 m1Span
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: F344-Slc6a3^m1Span

Symbol:

F344-Slc6a3^m1Span

Strain:

F344-Slc6a3^m1

Substrain:

Span

RGD ID:

126925196

Citation ID:

RRID:RGD_126925196

Ontology ID:

RS:0004942

Alleles:

Slc6a3^m1Span

Type:

mutant

Source:

Central Institute of Mental Health Department of Psychopharmacology Central Institute of Mental Health Mannheim,

Origin:

This strain was identified in the N-ethyl-N-nitrosourea (ENU)-driven target-selected mutagenesis screen. A point mutation in the Slc6a3 (DAT) coding sequence (exon 3) with a T/G transversion at nucleotide position 471 was identified in a male rat. This nucleotide exchange leads to substitution of an asparagine amino acid residue by a lysine residue at position 157 (N157K) in the SLC6A3 (DAT) protein, which introduces new positive charge into the amino acid sequence.

Genetic Status:

Homozygous

Last Known Status:

Unknown

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	29,709,443 - 29,750,413	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	1	32,323,011 - 32,363,983	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	1	33,745,060 - 33,788,878	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	1	30,516,568 - 30,557,540	RGD_MAPPER_PIPELINE	RGSC3.4

Annotation Click to see Annotation Detail View

References

Region

Additional Information

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: F344-Slc6a3m1Span

Strain: F344-Slc6a3^m1Span