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Gene: Pkhd1 (PKHD1 ciliary IPT domain containing fibrocystin/polyductin) Rattus norvegicus
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Symbol: Pkhd1
Name: PKHD1 ciliary IPT domain containing fibrocystin/polyductin
RGD ID: 1308476
Description: Predicted to be involved in several processes, including negative regulation of NF-kappaB transcription factor activity; regulation of centrosome duplication; and regulation of intracellular signal transduction. Localizes to cilium and membrane. Used to study autosomal recessive polycystic kidney disease. Biomarker of autosomal recessive polycystic kidney disease. Human ortholog(s) of this gene implicated in autosomal recessive polycystic kidney disease and polycystic kidney disease 4. Orthologous to human PKHD1 (PKHD1 ciliary IPT domain containing fibrocystin/polyductin); INTERACTS WITH bisphenol A; cefaloridine; rotenone.
Type: protein-coding
RefSeq Status: MODEL
Also known as: fibrocystin; LOC301287; LOW QUALITY PROTEIN: fibrocystin; PKHD1, fibrocystin/polyductin; polycystic kidney and hepatic disease 1; polycystic kidney and hepatic disease 1 (autosomal recessive); polycystic kidney and hepatic disease 1 homolog; polycystic kidney and hepatic disease 1 homolog (human)
Orthologs:
Allele / Splice: Pkhd1pck  
Genetic Models: PCK-P2rx7em8Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0926,164,969 - 26,736,704 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0925,025,958 - 25,065,045 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0925,159,062 - 25,593,163 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4918,833,903 - 19,338,716 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1918,831,224 - 19,254,940 (-)NCBI
Celera920,127,204 - 20,618,569 (-)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pkhd1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308476
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.