Despr5 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Despr5 (Despair related QTL 5) Rattus norvegicus

Symbol: Despr5
Name: Despair related QTL 5
RGD ID: 1354650
Previously known as: Immobility QTL 5; Desp5
Trait: locomotor behavior trait   (VT:0001392)    
Measurement Type: amount of time spent in voluntary immobility   (CMO:0001043)    
LOD Score: 4.01
P Value: 0.0017
Variance: 2.9
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr898,750,492 - 53,750,492RGD_MAPPER_PIPELINE
mRatBN7.291,254,084 - 46,254,084RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.094,986,095 - 49,986,095RGD_MAPPER_PIPELINERnor6.0
Rnor_5.093,833,388 - 48,833,388RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.491 - 42,602,240RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.190 - 42,599,949RGD
Cross Type: Not Available
Strains Crossed: WKY/NHsd F344/NHsd 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Despr5Ratdepressive disorder  IAGP 1302894 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Despr5Ratbehavioral despair  IAGP 1302894 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Despr5Ratamount of time spent in voluntary immobility  IDA 1302894 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Despr5Ratcontrol condition  IDA 1302894 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Despr5RatMorris water maze method  IDA 1302894 RGD 
Despr5Ratvisual assessment of in vivo video recording  IDA 1302894 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Despr5RatF344/NHsd  IEA 1302894 RGD 
Despr5RatWKY/NHsd  IEA 1302894 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Despr5Ratlocomotor behavior trait  IDA 1302894 RGD 


#
Reference Title
Reference Citation
1. Sex- and lineage-specific inheritance of depression-like behavior in the rat. Solberg LC, etal., Mamm Genome 2004 Aug;15(8):648-62.
2. Identification of genetic loci involved in diabetes using a rat model of depression. Solberg Woods LC, etal., Mamm Genome. 2009 Aug 22.

Related QTL Description Reference
Gluco54 maps to same region RGD:2312611



1 to 20 of 589 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
3452Ptprsprotein tyrosine phosphatase, receptor type, S912454081307015Rat
1563631Znrf4zinc and ring finger 4913533081354496Rat
9685200TincrTINCR ubiquitin domain containing913871051389337Rat
1588577Safb2scaffold attachment factor B2913958521417010Rat
620613Safbscaffold attachment factor B914174491438408Rat
1588578Micos13mitochondrial contact site and cristae organizing system subunit 13914398411441782Rat
62085Rpl36ribosomal protein L36914419861447397Rat
621598Lonp1lon peptidase 1, mitochondrial914474441459771Rat
1594167Catsperdcation channel sperm associated auxiliary subunit delta914599671498342Rat
1589604Ranbp3RAN binding protein 3915072331544460Rat
41237504Capscalcyphosine915445971545631Rat
1303340Vmacvimentin-type intermediate filament associated coiled-coil protein915467471550417Rat
1303292Ndufa11NADH:ubiquinone oxidoreductase subunit A11915504871554546Rat
1588473Fut4-ps1fucosyltransferase 4, pseudogene 1915696051572022Rat
621494Nrtnneurturin915818601587835Rat
1563228Dus3ldihydrouridine synthase 3-like915934911598663Rat
1595447Prr22proline rich 22915991691601003Rat
1588579Rfx2regulatory factor X2916046361671220Rat
41282109LOC120094598uncharacterized LOC120094598916455991648694Rat
1589605Myl12b-ps2myosin light chain 12B, pseudogene 2916783361679276Rat

1 to 20 of 589 rows
1 to 20 of 699 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10252D7Mit1213691077552010775580Ratregion
10252D7Mit1213693513366635133728Ratregion
10873D9Uwm39991455455514554654Ratregion
33979D9Mit420494243579742436001Ratregion
34090D9Mgh822393684038536840608Ratregion
34264D9Mgh5167958577835857951Ratregion
34286D9Mgh614393145248931452632Ratregion
34413D9Mgh314894077390540774051Ratregion
33583D9Mit927192315912623159388Ratregion
36063D9Rat3717191588777915887950Ratregion
36151D9Rat4615991076977510769932Ratregion
36157D9Rat3116192121837921218540Ratregion
37220D9Rat7320194004371240043913Ratregion
37416D9Rat7019092526804425268236Ratregion
37468D9Rat162221933686523368873Ratregion
37472D9Rat8722891868264518682873Ratregion
37530D9Rat10421694535995545360171Ratregion
35336D9Rat3928891563800415638292Ratregion
35437D9Rat3816491590616415906328Ratregion
35439D9Rat3513391722047617220609Ratregion
1 to 20 of 699 rows

Peak: (D9Rat130)
Rat AssemblyChrPosition (strand)Source
GRCr8931,250,432 - 31,250,552 (+)Marker Load Pipeline
mRatBN7.2923,754,024 - 23,754,144 (+)MAPPER
Rnor_6.0927,486,036 - 27,486,155NCBI
Rnor_5.0926,333,329 - 26,333,448UniSTS
RGSC_v3.4920,102,034 - 20,102,447RGD
RGSC_v3.4920,102,047 - 20,102,166UniSTS
RGSC_v3.1920,099,890 - 20,100,009RGD
Celera921,328,905 - 21,329,024UniSTS
RH 3.4 Map9230.2UniSTS
RH 3.4 Map9230.2RGD
RH 2.0 Map9202.5RGD
SHRSP x BN Map920.1498RGD
Cytogenetic Map9q13UniSTS


1 to 10 of 45 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)92375402458157242Rat

1 to 10 of 45 rows


Database
Acc Id
Source(s)
NCBI Gene Despr5


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-04-14 Despr5  Despair related QTL 5  Desp5    Symbol updated 1299863 APPROVED

Note Type Note Reference