Tbcc (tubulin folding cofactor C)

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Gene: Tbcc (tubulin folding cofactor C) Rattus norvegicus

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Symbol:

Tbcc

Name:

tubulin folding cofactor C

RGD ID:

1306756

Description:

Predicted to enable GTPase activity. Predicted to be involved in post-chaperonin tubulin folding pathway and tubulin complex assembly. Predicted to be located in cytosol and photoreceptor connecting cilium. Predicted to be active in cytoplasm. Orthologous to human TBCC (tubulin folding cofactor C); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC316221; tubulin-specific chaperone C

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TBCC (tubulin folding cofactor C)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Tbcc (tubulin-specific chaperone C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tbcc (tubulin folding cofactor C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TBCC (tubulin folding cofactor C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TBCC (tubulin folding cofactor C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tbcc (tubulin folding cofactor C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TBCC (tubulin folding cofactor C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TBCC (tubulin folding cofactor C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tbcc (tubulin folding cofactor C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TBCC (tubulin folding cofactor C)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tbcc (tubulin-specific chaperone C)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tbcc (tubulin folding cofactor C)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	TBCC	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	tbcc-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tbcc	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	21,596,472 - 21,597,660 (-)	NCBI		GRCr8
mRatBN7.2	9	14,098,855 - 14,100,043 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	14,098,868 - 14,100,042 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	22,681,090 - 22,682,278 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	27,744,644 - 27,745,832 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	26,044,455 - 26,045,643 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	16,405,187 - 16,406,338 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	16,405,185 - 16,406,338 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	15,314,054 - 15,315,205 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	9,294,924 - 9,296,075 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	9,292,369 - 9,293,392 (-)	NCBI
Celera	9	11,847,513 - 11,848,664 (-)	NCBI		Celera
Cytogenetic Map	9	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

infantile Refsum disease (ISO)

Zellweger syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-hydroxy-17-methylestra-4,9,11-trien-3-one (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-hydroxypropanoic acid (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP,ISO)

choline (ISO)

clobetasol (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

dextran sulfate (ISO)

dibenzo[a,l]pyrene (ISO)

Dibutyl phosphate (ISO)

diethylstilbestrol (EXP,ISO)

doxorubicin (ISO)

emodin (ISO)

endosulfan (EXP)

folic acid (ISO)

gentamycin (EXP)

indometacin (ISO)

irinotecan (ISO)

ketoconazole (EXP,ISO)

L-methionine (ISO)

leflunomide (ISO)

N(4)-hydroxycytidine (ISO)

paracetamol (ISO)

rac-lactic acid (ISO)

rotenone (EXP,ISO)

sarin (ISO)

temozolomide (ISO)

thiram (ISO)

trichloroethene (EXP)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

post-chaperonin tubulin folding pathway (ISO)

protein folding (IBA)

tubulin complex assembly (IBA)

Cellular Component

cytoplasm (IBA,ISO)

cytosol (IEA,ISO)

photoreceptor connecting cilium (ISO)

Molecular Function

GTPase activity (ISO)

protein binding (ISO)

tubulin binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11847227	PMID:12417528	PMID:12477932	PMID:22871113

Genomics

Comparative Map Data

Tbcc
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	21,596,472 - 21,597,660 (-)	NCBI		GRCr8
mRatBN7.2	9	14,098,855 - 14,100,043 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	14,098,868 - 14,100,042 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	22,681,090 - 22,682,278 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	27,744,644 - 27,745,832 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	26,044,455 - 26,045,643 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	16,405,187 - 16,406,338 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	16,405,185 - 16,406,338 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	15,314,054 - 15,315,205 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	9,294,924 - 9,296,075 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	9,292,369 - 9,293,392 (-)	NCBI
Celera	9	11,847,513 - 11,848,664 (-)	NCBI		Celera
Cytogenetic Map	9	q12	NCBI

TBCC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	42,744,498 - 42,746,103 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	42,744,498 - 42,746,103 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	42,712,236 - 42,713,841 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	42,820,212 - 42,821,862 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	42,820,237 - 42,821,812	NCBI
Celera	6	44,264,486 - 44,266,136 (-)	NCBI		Celera
Cytogenetic Map	6	p21.1	NCBI
HuRef	6	42,430,373 - 42,432,023 (-)	NCBI		HuRef
CHM1_1	6	42,714,735 - 42,716,385 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	42,573,235 - 42,574,840 (-)	NCBI		T2T-CHM13v2.0

Tbcc
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	47,201,547 - 47,203,389 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	47,201,610 - 47,202,773 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	46,890,621 - 46,892,463 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	46,890,684 - 46,891,847 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	47,027,570 - 47,029,412 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	46,353,812 - 46,355,654 (+)	NCBI		MGSCv36	mm8
Celera	17	50,326,534 - 50,328,376 (+)	NCBI		Celera
Cytogenetic Map	17	C	NCBI
cM Map	17	22.9	NCBI

Tbcc
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955437	8,808,021 - 8,809,598 (-)	NCBI	ChiLan1.0	ChiLan1.0

TBCC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	57,242,809 - 57,244,479 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	53,112,795 - 53,114,484 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	42,334,902 - 42,336,560 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	43,630,273 - 43,631,992 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	43,630,810 - 43,631,943 (-)	Ensembl	panpan1.1		panPan2

TBCC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	11,332,736 - 11,334,799 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	11,333,676 - 11,334,842 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	11,359,961 - 11,362,012 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	11,814,282 - 11,816,335 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	11,815,224 - 11,816,390 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	11,342,240 - 11,344,289 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	11,426,925 - 11,428,976 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	11,520,795 - 11,522,848 (-)	NCBI		UU_Cfam_GSD_1.0

Tbcc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	46,812,898 - 46,814,253 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	17,146,017 - 17,147,054 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	17,145,956 - 17,147,299 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TBCC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	37,822,767 - 37,824,953 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	37,822,764 - 37,823,994 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	43,248,570 - 43,249,800 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TBCC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	29,404,102 - 29,405,505 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666044	42,779,555 - 42,781,055 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tbcc
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624754	16,675,439 - 16,677,047 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tbcc
1 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	34
Count of miRNA genes:	34
Interacting mature miRNAs:	34
Transcripts:	ENSRNOT00000073079
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631211	Bw4	Body weight QTL4	5.31		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	9	5109826	50109826	Rat
10054141	Gmadr4	Adrenal mass QTL 4	2.45	0.0074	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	9	1	14209783	Rat
2303559	Gluco54	Glucose level QTL 54	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	1254084	46254084	Rat
7411609	Foco16	Food consumption QTL 16	25.6	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	8952560	53952560	Rat
61450	Ciaa3	CIA Autoantibody QTL 3	6.5		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	9	7954720	22071169	Rat
9589055	Scfw5	Subcutaneous fat weight QTL 5	5.55	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	9	1	37999212	Rat
1641911	Alcrsp13	Alcohol response QTL 13			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	1	43718459	Rat
1354650	Despr5	Despair related QTL 5	4.01	0.0017	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	9	1254084	46254084	Rat
1300124	Cm4	Cardiac mass QTL 4	3.55		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	9	1	40594091	Rat
61425	Cia15	Collagen induced arthritis QTL 15	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	9	5109826	42921101	Rat
70226	Eae4	Experimental allergic encephalomyelitis QTL 4			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	9	1	25661317	Rat
9589158	Gluco65	Glucose level QTL 65	6.82	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	9	1	37999212	Rat
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
1600365	Mcs20	Mammary carcinoma susceptibility QTL 20	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	9	13533770	42791750	Rat
11353947	Bp392	Blood pressure QTL 392			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	7283252	52283252	Rat
7411592	Foco8	Food consumption QTL 8	7.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	1	37999212	Rat
1331757	Cdexp1	CD45RC expression in CD8 T cells QTL 1	4.3		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	9	1024537	67509080	Rat
1298088	Edpm11	Estrogen-dependent pituitary mass QTL 11	2.5		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	1	43718459	Rat
9589133	Insul26	Insulin level QTL 26	17.96	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	9	8952560	53952560	Rat

Markers in Region

RH130690

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	14,098,962 - 14,099,157 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	16,405,275 - 16,405,469	NCBI	Rnor6.0
Rnor_5.0	9	15,314,142 - 15,314,336	UniSTS	Rnor5.0
RGSC_v3.4	9	9,295,012 - 9,295,206	UniSTS	RGSC3.4
Celera	9	11,847,601 - 11,847,795	UniSTS
Cytogenetic Map	9	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108200	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC166467	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000073079 ⟹ ENSRNOP00000065504

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	14,098,868 - 14,100,042 (-)	Ensembl
Rnor_6.0 Ensembl	9	16,405,185 - 16,406,338 (-)	Ensembl

RefSeq Acc Id:

NM_001108200 ⟹ NP_001101670

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	21,596,472 - 21,597,660 (-)	NCBI
mRatBN7.2	9	14,098,855 - 14,100,043 (-)	NCBI
Rnor_6.0	9	16,405,187 - 16,406,338 (-)	NCBI
Rnor_5.0	9	15,314,054 - 15,315,205 (-)	NCBI
RGSC_v3.4	9	9,294,924 - 9,296,075 (-)	RGD
Celera	9	11,847,513 - 11,848,664 (-)	RGD

Sequence:

show sequence

TCAAGATGGAGGGAGTGGACTGCTCGGTGGCTCTGGCGGACGCTGCCGCCGGGTCCCCGCGGGA
CCTGAGCCTGGTACCCGAGCGACTTCAGAGGCGCGAGCAGGAGCGACAGATGGAGGTGGAGAGG
CGCAAGCAGAAGCGGCAGGACCAGGAGGTGGAGGAGGAGAAGAGCGGCTTCTTCGCCGCCGCCT
TCGCCCGGGAGCGCGCGGCAGCGGAGGAGCTGCTGCAGGGCGAGGCGTCGGCCGAGCGGCTGGA
AGAGGCGGCCAACCGGCTCCAGGCGCTGCGGAAACTCTTGAACGACTCGGTTCTGTTCCTCGCT
GCCTACGACCTGCGGCAGGGCCAGGCGGCGCTGGCGCAGCTGCAGTCGGTCCTAACGGAACGGC
GCCAGGAGCTGCAGCCCAAGAAGCGCTTCGCCTTCAAGGCTCGAAAGAAGGATGCTGCCGGGAC
TGCCCAGGTAGATGCCGCACCCGTCACCTCGGCGGCCCCTTCTCCTCCCTTGACCGAGGAGGAG
GGAGCTCCCGGGGCCAGCTGGGCCTGTGGCTTCTCCAACCTGGAATCCCAAGATCTGGAGAAGA
GAGCGGAGGAGCTGCACCAGCGTGACATTCTTTTGAGCGACCTGACCAACTGCACTGTCAGACT
GCGTGGCAATCCCAACACCTTGCGGTTGGCAAAGGCCCGAGGCTGCAAGGTGCTCTGCGGCCCA
GTGACCACCTCTGTGTTCCTGGAGGACTGTCGAGATTGCATCCTGGCTGTGGCTTGCCAGCAGC
TCCGCGTACACACTACCAAAGACACCCGCATCTTCTTGCAGGTGACCAGCAGGGCCATCGTGGA
GGACTGCAGCGGCATCCAGTTTGCTCCTTACACCTGGAGCTACCCTGGGATCGACAAGGACTTC
CAGGACTCCGGTTTAGATAGGAGCAAAAATAACTGGAACCAGGTTGACGATTTCAATTGGCTAG
CCCAAAATGTGCCCTCCCCAAATTGGAGTATTCTTCCTGAGGAGGATCGAGACATCCAGTGGGA
CTGAGCACTGGCCACGCTCAGTGACATCCCAATCGGTTTACCTGATATTGTTCTGTTTATGTTT
GGAGTAGTAGGGGCTTGAAATTGTTGAAACTCCCCTCCTTGTGAGTCCTATTAAATTTCATAAC
GGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

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Protein Sequences


Protein RefSeqs	NP_001101670	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66467	(Get FASTA)	NCBI Sequence Viewer
	EDM18866	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000065504.1

RefSeq Acc Id:

NP_001101670 ⟸ NM_001108200

- UniProtKB:

B2GUZ7 (UniProtKB/TrEMBL), M0R7S2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEGVDCSVALADAAAGSPRDLSLVPERLQRREQERQMEVERRKQKRQDQEVEEEKSGFFAAAFA
RERAAAEELLQGEASAERLEEAANRLQALRKLLNDSVLFLAAYDLRQGQAALAQLQSVLTERRQ
ELQPKKRFAFKARKKDAAGTAQVDAAPVTSAAPSPPLTEEEGAPGASWACGFSNLESQDLEKRA
EELHQRDILLSDLTNCTVRLRGNPNTLRLAKARGCKVLCGPVTTSVFLEDCRDCILAVACQQLR
VHTTKDTRIFLQVTSRAIVEDCSGIQFAPYTWSYPGIDKDFQDSGLDRSKNNWNQVDDFNWLAQ
NVPSPNWSILPEEDRDIQWD

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Ensembl Acc Id:

ENSRNOP00000065504 ⟸ ENSRNOT00000073079

Protein Domains

C-CAP/cofactor C-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B2GUZ7-F1-model_v2	AlphaFold	B2GUZ7	1-340	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696501

Promoter ID:

EPDNEW_R7026

Type:

multiple initiation site

Name:

Tbcc_1

Description:

tubulin folding cofactor C

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	16,406,342 - 16,406,402	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306756	AgrOrtholog
BioCyc Gene	G2FUF-28250	BioCyc
Ensembl Genes	ENSRNOG00000048291	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000073079.3	UniProtKB/TrEMBL
Gene3D-CATH	1.20.58.1250	UniProtKB/TrEMBL
	2.160.20.70	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:9035211	IMAGE-MGC_LOAD
InterPro	C-CAP_CF_C-like	UniProtKB/TrEMBL
	CAP/MinC_C	UniProtKB/TrEMBL
	CARP_motif	UniProtKB/TrEMBL
	TBCC	UniProtKB/TrEMBL
	TBCC_N	UniProtKB/TrEMBL
	TBCC_N_sf	UniProtKB/TrEMBL
	Tubulin-bd_cofactor_C	UniProtKB/TrEMBL
KEGG Report	rno:316221	UniProtKB/TrEMBL
MGC_CLONE	MGC:187838	IMAGE-MGC_LOAD
NCBI Gene	316221	ENTREZGENE
PANTHER	PTHR15139	UniProtKB/TrEMBL
	TUBULIN-SPECIFIC CHAPERONE C	UniProtKB/TrEMBL
Pfam	TBCC	UniProtKB/TrEMBL
	TBCC_N	UniProtKB/TrEMBL
PhenoGen	Tbcc	PhenoGen
PROSITE	C_CAP_COFACTOR_C	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000048291	RatGTEx
SMART	CARP	UniProtKB/TrEMBL
UniProt	B2GUZ7	ENTREZGENE, UniProtKB/TrEMBL
	M0R7S2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-10-23	Tbcc	tubulin folding cofactor C	Tbcc	tubulin-specific chaperone c	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Tbcc	tubulin-specific chaperone c	Tbcc_predicted	tubulin-specific chaperone c (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Tbcc_predicted	tubulin-specific chaperone c (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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