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Gene: Brcc3 (BRCA1/BRCA2-containing complex, subunit 3) Rattus norvegicus
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Symbol: Brcc3
Name: BRCA1/BRCA2-containing complex, subunit 3
Description: Predicted to have enzyme regulator activity; peptidase activity, acting on L-amino acid peptides; and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in several processes, including histone H2A K63-linked deubiquitination; response to X-ray; and signal transduction involved in G2 DNA damage checkpoint. Predicted to localize to the cytoplasm and nucleus. Orthologous to human BRCC3 (BRCA1/BRCA2-containing complex subunit 3); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INTERACTS WITH 3H-1,2-dithiole-3-thione; bisphenol A; C60 fullerene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: BRCA1-A complex subunit BRCC36; BRCA1/BRCA2-containing complex subunit 3; BRCA1/BRCA2-containing complex subunit 36; BRISC complex subunit BRCC36; LOC316794; lys-63-specific deubiquitinase BRCC36; similar to BRCA1/BRCA2-containing complex subunit 36 isoform 2
Orthologs:
Homo sapiens (human) : BRCC3 (BRCA1/BRCA2-containing complex subunit 3)  HGNC  Alliance
Mus musculus (house mouse) : Brcc3 (BRCA1/BRCA2-containing complex, subunit 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Brcc3 (BRCA1/BRCA2-containing complex subunit 3)
Pan paniscus (bonobo/pygmy chimpanzee) : BRCC3 (BRCA1/BRCA2-containing complex subunit 3)
Canis lupus familiaris (dog) : BRCC3 (BRCA1/BRCA2-containing complex subunit 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Brcc3 (BRCA1/BRCA2-containing complex subunit 3)
Sus scrofa (pig) : BRCC3 (BRCA1/BRCA2-containing complex subunit 3)
more info ...
Related Pseudogenes: Brcc3-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.099,863,380 - 9,865,920 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.098,864,902 - 8,867,442 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera96,530,917 - 6,533,459 (-)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Brcc3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1588543
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.