Ptpn18 (protein tyrosine phosphatase, non-receptor type 18) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Ptpn18 (protein tyrosine phosphatase, non-receptor type 18) Rattus norvegicus
Analyze
Symbol: Ptpn18
Name: protein tyrosine phosphatase, non-receptor type 18
RGD ID: 1311586
Description: Predicted to enable non-membrane spanning protein tyrosine phosphatase activity. Predicted to act upstream of or within blastocyst formation. Predicted to be active in cytoplasm and nucleus. Orthologous to human PTPN18 (protein tyrosine phosphatase non-receptor type 18); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC301333; MGC112761; MGC112828; protein tyrosine phosphatase 20; PTP20; tyrosine-protein phosphatase non-receptor type 18
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8944,166,571 - 44,185,885 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl944,168,269 - 44,186,917 (+)EnsemblGRCr8
mRatBN7.2936,672,325 - 36,689,963 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl936,672,362 - 36,690,995 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx945,169,307 - 45,186,895 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0950,300,477 - 50,318,070 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0948,582,395 - 48,599,979 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0940,972,089 - 40,988,790 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl940,972,089 - 40,988,790 (+)Ensemblrn6Rnor6.0
Rnor_5.0940,642,603 - 40,659,304 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4933,197,524 - 33,214,470 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera934,462,489 - 34,479,260 (+)NCBICelera
RGSC_v3.1933,198,937 - 33,215,882 (+)NCBI
Cytogenetic Map9q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bisphenol F  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cobalt dichloride  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
flutamide  (EXP)
folic acid  (ISO)
fonofos  (ISO)
gentamycin  (EXP)
indometacin  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
lidocaine  (EXP)
methotrexate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodimethylamine  (EXP)
nickel sulfate  (ISO)
nitrates  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
terbufos  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISO)
nucleus  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8875997   PMID:12477932   PMID:25081058   PMID:27869233  


Genomics

Comparative Map Data
Ptpn18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8944,166,571 - 44,185,885 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl944,168,269 - 44,186,917 (+)EnsemblGRCr8
mRatBN7.2936,672,325 - 36,689,963 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl936,672,362 - 36,690,995 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx945,169,307 - 45,186,895 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0950,300,477 - 50,318,070 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0948,582,395 - 48,599,979 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0940,972,089 - 40,988,790 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl940,972,089 - 40,988,790 (+)Ensemblrn6Rnor6.0
Rnor_5.0940,642,603 - 40,659,304 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4933,197,524 - 33,214,470 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera934,462,489 - 34,479,260 (+)NCBICelera
RGSC_v3.1933,198,937 - 33,215,882 (+)NCBI
Cytogenetic Map9q21NCBI
PTPN18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382130,356,056 - 130,375,405 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2130,356,045 - 130,375,405 (+)Ensemblhg38GRCh38
GRCh372131,113,629 - 131,132,978 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362130,830,088 - 130,848,614 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342130,829,847 - 130,848,373NCBI
Celera2124,386,923 - 124,406,317 (+)NCBICelera
Cytogenetic Map2q21.1NCBI
HuRef2123,403,555 - 123,422,890 (+)NCBIHuRef
CHM1_12131,117,321 - 131,136,723 (+)NCBICHM1_1
T2T-CHM13v2.02130,789,979 - 130,809,308 (+)NCBIT2T-CHM13v2.0
Ptpn18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39134,498,827 - 34,514,811 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl134,498,843 - 34,514,814 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38134,459,729 - 34,473,784 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl134,459,762 - 34,475,733 (+)Ensemblmm10GRCm38
MGSCv37134,516,591 - 34,530,629 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36134,404,304 - 34,418,330 (+)NCBIMGSCv36mm8
Celera134,223,007 - 34,236,930 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map113.25NCBI
Ptpn18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545965,612 - 91,545 (+)Ensembl
ChiLan1.0NW_00495545965,191 - 90,459 (+)NCBIChiLan1.0ChiLan1.0
PTPN18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21343,899,043 - 43,938,940 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B43,908,905 - 43,937,138 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B28,642,193 - 28,662,242 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B131,270,974 - 131,287,803 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B131,270,974 - 131,287,803 (+)EnsemblpanPan2panpan1.1
PTPN18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12518,996,194 - 19,010,715 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2519,028,649 - 19,047,363 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02519,135,117 - 19,151,064 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.12518,996,547 - 19,015,182 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02519,008,931 - 19,024,808 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02519,065,452 - 19,084,167 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ptpn18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303100,499,935 - 100,513,124 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493646941,104,698 - 41,117,753 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPN18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1531,945,897 - 31,965,753 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11531,945,901 - 31,966,571 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21535,772,241 - 35,792,658 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPN18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11027,777 - 53,757 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1036,192 - 53,174 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660585,664,601 - 5,690,253 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptpn18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473214,495,732 - 14,545,775 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptpn18
105 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:161
Count of miRNA genes:134
Interacting mature miRNAs:147
Transcripts:ENSRNOT00000067928
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)92375402458157242Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
724543Cm20Cardiac mass QTL 203.9heart mass (VT:0007028)calculated heart weight (CMO:0000073)91696139840594091Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)92213332249968732Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat

Markers in Region
RH129623  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2936,689,754 - 36,689,952 (+)MAPPERmRatBN7.2
Rnor_6.0940,989,366 - 40,989,563NCBIRnor6.0
Rnor_5.0940,659,880 - 40,660,077UniSTSRnor5.0
RGSC_v3.4933,223,597 - 33,223,794UniSTSRGSC3.4
RGSC_v3.4933,215,046 - 33,215,243UniSTSRGSC3.4
Celera934,479,836 - 34,480,033UniSTS
RH 3.4 Map9341.7UniSTS
Cytogenetic Map9q21UniSTS
RH130628  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2936,686,841 - 36,687,052 (+)MAPPERmRatBN7.2
Rnor_6.0940,986,453 - 40,986,663NCBIRnor6.0
Rnor_5.0940,656,967 - 40,657,177UniSTSRnor5.0
RGSC_v3.4933,212,133 - 33,212,343UniSTSRGSC3.4
Celera934,476,919 - 34,477,129UniSTS
RH 3.4 Map9340.9UniSTS
Cytogenetic Map9q21UniSTS
RH137148  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2936,689,752 - 36,689,919 (+)MAPPERmRatBN7.2
Rnor_6.0940,989,364 - 40,989,530NCBIRnor6.0
Rnor_5.0940,659,878 - 40,660,044UniSTSRnor5.0
RGSC_v3.4933,223,595 - 33,223,761UniSTSRGSC3.4
RGSC_v3.4933,215,044 - 33,215,210UniSTSRGSC3.4
Celera934,479,834 - 34,480,000UniSTS
Cytogenetic Map9q21UniSTS
RH139796  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8944,184,244 - 44,184,822 (+)Marker Load Pipeline
mRatBN7.2936,688,322 - 36,688,900 (+)MAPPERmRatBN7.2
Rnor_6.0940,987,934 - 40,988,511NCBIRnor6.0
Rnor_5.0940,658,448 - 40,659,025UniSTSRnor5.0
RGSC_v3.4933,222,165 - 33,222,742UniSTSRGSC3.4
RGSC_v3.4933,213,614 - 33,214,191UniSTSRGSC3.4
Celera934,478,404 - 34,478,981UniSTS
RH 3.4 Map9344.0UniSTS
Cytogenetic Map9q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 142 81 92 31 16 16

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001013111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005488868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC093398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC098788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U69673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000067928   ⟹   ENSRNOP00000061226
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl944,168,269 - 44,186,917 (+)Ensembl
mRatBN7.2 Ensembl936,672,388 - 36,690,995 (+)Ensembl
Rnor_6.0 Ensembl940,972,089 - 40,988,790 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084470   ⟹   ENSRNOP00000069204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl944,168,301 - 44,185,884 (+)Ensembl
mRatBN7.2 Ensembl936,682,984 - 36,687,756 (+)Ensembl
Rnor_6.0 Ensembl940,975,836 - 40,987,098 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095122   ⟹   ENSRNOP00000079548
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl944,168,269 - 44,185,884 (+)Ensembl
mRatBN7.2 Ensembl936,672,362 - 36,689,308 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116074   ⟹   ENSRNOP00000092277
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl944,168,269 - 44,185,884 (+)Ensembl
mRatBN7.2 Ensembl936,672,371 - 36,689,308 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000161797   ⟹   ENSRNOP00000108231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl944,168,760 - 44,185,884 (+)Ensembl
RefSeq Acc Id: NM_001013111   ⟹   NP_001013129
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,168,297 - 44,185,885 (+)NCBI
mRatBN7.2936,672,372 - 36,689,963 (+)NCBI
Rnor_6.0940,972,089 - 40,988,790 (+)NCBI
Rnor_5.0940,642,603 - 40,659,304 (+)NCBI
RGSC_v3.4933,197,524 - 33,214,470 (+)RGD
Celera934,462,489 - 34,479,260 (+)RGD
Sequence:
RefSeq Acc Id: XM_039083208   ⟹   XP_038939136
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,168,249 - 44,185,885 (+)NCBI
mRatBN7.2936,672,326 - 36,689,963 (+)NCBI
RefSeq Acc Id: XM_039083210   ⟹   XP_038939138
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,168,248 - 44,184,380 (+)NCBI
mRatBN7.2936,672,325 - 36,688,418 (+)NCBI
RefSeq Acc Id: XM_039083211   ⟹   XP_038939139
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,177,401 - 44,185,885 (+)NCBI
mRatBN7.2936,681,479 - 36,689,963 (+)NCBI
RefSeq Acc Id: XM_039083213   ⟹   XP_038939141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,177,404 - 44,185,885 (+)NCBI
mRatBN7.2936,681,481 - 36,689,963 (+)NCBI
RefSeq Acc Id: XM_039083214   ⟹   XP_038939142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,168,248 - 44,183,499 (+)NCBI
mRatBN7.2936,672,325 - 36,687,580 (+)NCBI
RefSeq Acc Id: XM_039083215   ⟹   XP_038939143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,168,248 - 44,183,532 (+)NCBI
mRatBN7.2936,672,325 - 36,687,614 (+)NCBI
RefSeq Acc Id: XM_039083217   ⟹   XP_038939145
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,174,536 - 44,185,885 (+)NCBI
mRatBN7.2936,681,347 - 36,689,963 (+)NCBI
RefSeq Acc Id: XM_063266878   ⟹   XP_063122948
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,168,248 - 44,185,885 (+)NCBI
RefSeq Acc Id: XM_063266879   ⟹   XP_063122949
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,168,248 - 44,185,885 (+)NCBI
RefSeq Acc Id: XM_063266880   ⟹   XP_063122950
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,168,248 - 44,185,885 (+)NCBI
RefSeq Acc Id: XM_063266881   ⟹   XP_063122951
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,177,380 - 44,185,885 (+)NCBI
RefSeq Acc Id: XM_063266882   ⟹   XP_063122952
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,168,272 - 44,185,885 (+)NCBI
RefSeq Acc Id: XM_063266883   ⟹   XP_063122953
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,168,248 - 44,184,380 (+)NCBI
RefSeq Acc Id: XM_063266884   ⟹   XP_063122954
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,177,382 - 44,185,885 (+)NCBI
RefSeq Acc Id: XM_063266885   ⟹   XP_063122955
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,174,536 - 44,185,885 (+)NCBI
RefSeq Acc Id: XM_063266886   ⟹   XP_063122956
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,166,571 - 44,185,885 (+)NCBI
RefSeq Acc Id: XM_063266887   ⟹   XP_063122957
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,171,852 - 44,185,885 (+)NCBI
RefSeq Acc Id: XM_063266888   ⟹   XP_063122958
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,177,645 - 44,185,885 (+)NCBI
RefSeq Acc Id: XR_005488868
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8944,168,248 - 44,184,266 (+)NCBI
mRatBN7.2936,672,325 - 36,688,344 (+)NCBI
RefSeq Acc Id: NP_001013129   ⟸   NM_001013111
- UniProtKB: A6INA1 (UniProtKB/TrEMBL),   P70602 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069204   ⟸   ENSRNOT00000084470
Ensembl Acc Id: ENSRNOP00000061226   ⟸   ENSRNOT00000067928
RefSeq Acc Id: XP_038939138   ⟸   XM_039083210
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038939143   ⟸   XM_039083215
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038939142   ⟸   XM_039083214
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038939136   ⟸   XM_039083208
- Peptide Label: isoform X4
- UniProtKB: P70602 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939145   ⟸   XM_039083217
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038939139   ⟸   XM_039083211
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038939141   ⟸   XM_039083213
- Peptide Label: isoform X10
Ensembl Acc Id: ENSRNOP00000092277   ⟸   ENSRNOT00000116074
Ensembl Acc Id: ENSRNOP00000079548   ⟸   ENSRNOT00000095122
RefSeq Acc Id: XP_063122956   ⟸   XM_063266886
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063122948   ⟸   XM_063266878
- Peptide Label: isoform X1
- UniProtKB: P70602 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122949   ⟸   XM_063266879
- Peptide Label: isoform X2
- UniProtKB: P70602 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122950   ⟸   XM_063266880
- Peptide Label: isoform X3
- UniProtKB: P70602 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122953   ⟸   XM_063266883
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063122952   ⟸   XM_063266882
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063122957   ⟸   XM_063266887
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063122955   ⟸   XM_063266885
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063122951   ⟸   XM_063266881
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063122954   ⟸   XM_063266884
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063122958   ⟸   XM_063266888
- Peptide Label: isoform X16
- UniProtKB: Q4KM54 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000108231   ⟸   ENSRNOT00000161797
Protein Domains
Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M8E7-F1-model_v2 AlphaFold F1M8E7 1-453 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696595
Promoter ID:EPDNEW_R7120
Type:single initiation site
Name:Ptpn18_1
Description:protein tyrosine phosphatase, non-receptor type 18
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0940,972,064 - 40,972,124EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311586 AgrOrtholog
BioCyc Gene G2FUF-27860 BioCyc
Ensembl Genes ENSRNOG00000013415 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067928.4 UniProtKB/TrEMBL
  ENSRNOT00000084470.2 UniProtKB/TrEMBL
  ENSRNOT00000095122 ENTREZGENE
  ENSRNOT00000095122.1 UniProtKB/TrEMBL
  ENSRNOT00000116074 ENTREZGENE
  ENSRNOT00000116074.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.190.10 UniProtKB/TrEMBL
InterPro Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTN12/18/22 UniProtKB/TrEMBL
  Tyr/Dual-sp_Pase UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  Tyr_Pase_rcpt/non-rcpt UniProtKB/TrEMBL
KEGG Report rno:301333 UniProtKB/TrEMBL
NCBI Gene 301333 ENTREZGENE
PANTHER TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED UniProtKB/TrEMBL
  TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 18 UniProtKB/TrEMBL
Pfam Y_phosphatase UniProtKB/TrEMBL
PhenoGen Ptpn18 PhenoGen
PRINTS PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013415 RatGTEx
SMART PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/TrEMBL
UniProt A0A0G2JUS1_RAT UniProtKB/TrEMBL
  A0A8I5ZN88_RAT UniProtKB/TrEMBL
  A0A8I6AHV1_RAT UniProtKB/TrEMBL
  A6INA1 ENTREZGENE, UniProtKB/TrEMBL
  F1M8E7_RAT UniProtKB/TrEMBL
  P70602 ENTREZGENE, UniProtKB/TrEMBL
  Q4KM54 ENTREZGENE, UniProtKB/TrEMBL
  Q566Q5_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Ptpn18  protein tyrosine phosphatase, non-receptor type 18  Ptpn18_predicted  protein tyrosine phosphatase, non-receptor type 18 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ptpn18_predicted  protein tyrosine phosphatase, non-receptor type 18 (predicted)      Symbol and Name status set to approved 70820 APPROVED