Adgre1 (adhesion G protein-coupled receptor E1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Adgre1 (adhesion G protein-coupled receptor E1) Rattus norvegicus
Analyze
Symbol: Adgre1
Name: adhesion G protein-coupled receptor E1
RGD ID: 1359214
Description: Predicted to enable G protein-coupled receptor activity. Involved in cellular response to transforming growth factor beta stimulus and cellular response to tumor necrosis factor. Predicted to be located in external side of plasma membrane. Predicted to be active in plasma membrane. Orthologous to human ADGRE1 (adhesion G protein-coupled receptor E1); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: adhesion G protein-coupled receptor E2; cell surface glycoprotein EMR1; EGF-like module containing, mucin-like, hormone receptor-like 1; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; Emr1; EMR1 hormone receptor
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr892,329,398 - 2,484,959 (+)NCBIGRCr8
mRatBN7.292,242,476 - 2,398,000 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl92,242,474 - 2,398,000 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx92,669,775 - 2,827,086 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.098,019,173 - 8,176,462 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.096,975,024 - 7,132,310 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.099,431,888 - 9,585,883 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl99,431,860 - 9,585,865 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.098,434,335 - 8,593,088 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera96,128,947 - 6,277,689 (-)NCBICelera
Cytogenetic Map9q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-aminopurine  (ISO)
2-butoxyethanol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,3'-diindolylmethane  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
acrylamide  (ISO)
adenine  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
allyl methyl disulfide  (ISO)
amlexanox  (ISO)
amphetamine  (EXP)
argatroban  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
aspartame  (ISO)
atorvastatin calcium  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
carnosic acid  (ISO)
cefaloridine  (EXP)
celastrol  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
cobalt atom  (ISO)
cocaine  (EXP)
conjugated linoleic acid  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
Cuprizon  (EXP)
curcumin  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dioxygen  (EXP,ISO)
emodin  (ISO)
erlotinib hydrochloride  (ISO)
ethanol  (ISO)
ferric oxide  (ISO)
flavokawain B  (ISO)
folic acid  (ISO)
fructose  (EXP,ISO)
gadolinium trichloride  (EXP,ISO)
GW 4064  (ISO)
hexadecanoic acid  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (EXP)
manganese(0)  (EXP)
metformin  (ISO)
methotrexate  (ISO)
methylglyoxal  (ISO)
monosodium L-glutamate  (ISO)
Muraglitazar  (EXP)
N,N-dimethylformamide  (ISO)
N-nitrosodimethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
olaparib  (ISO)
oxycodone  (EXP)
ozone  (ISO)
paracetamol  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
propanal  (ISO)
quercetin  (ISO)
Rhein  (ISO)
rimonabant  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
streptozocin  (EXP,ISO)
tamibarotene  (ISO)
taurine  (ISO)
temozolomide  (ISO)
Tesaglitazar  (EXP)
testosterone  (EXP)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
triphenyl phosphate  (EXP,ISO)
Triptolide  (ISO)
troglitazone  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Characterization and identification of subpopulations of mononuclear preosteoclasts induced by TNF-α in combination with TGF-β in rats. Matsubara R, etal., PLoS One. 2012;7(10):e47930. doi: 10.1371/journal.pone.0047930. Epub 2012 Oct 24.
3. Molecular cloning of F4/80, a murine macrophage-restricted cell surface glycoprotein with homology to the G-protein-linked transmembrane 7 hormone receptor family. McKnight AJ, etal., J Biol Chem 1996 Jan 5;271(1):486-9.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10943842   PMID:11911823   PMID:11911824   PMID:12163569   PMID:15578266   PMID:21464233   PMID:23762286   PMID:24913911  


Genomics

Comparative Map Data
Adgre1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr892,329,398 - 2,484,959 (+)NCBIGRCr8
mRatBN7.292,242,476 - 2,398,000 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl92,242,474 - 2,398,000 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx92,669,775 - 2,827,086 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.098,019,173 - 8,176,462 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.096,975,024 - 7,132,310 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.099,431,888 - 9,585,883 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl99,431,860 - 9,585,865 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.098,434,335 - 8,593,088 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera96,128,947 - 6,277,689 (-)NCBICelera
Cytogenetic Map9q11NCBI
ADGRE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38196,887,579 - 6,940,450 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl196,887,566 - 6,940,459 (+)EnsemblGRCh38hg38GRCh38
GRCh37196,887,590 - 6,940,461 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36196,838,582 - 6,891,464 (+)NCBINCBI36Build 36hg18NCBI36
Build 34196,838,581 - 6,891,463NCBI
Celera196,829,806 - 6,881,535 (+)NCBICelera
Cytogenetic Map19p13.3-p13.2NCBI
HuRef196,649,934 - 6,703,041 (+)NCBIHuRef
CHM1_1196,887,377 - 6,940,296 (+)NCBICHM1_1
T2T-CHM13v2.0196,876,897 - 6,929,770 (+)NCBIT2T-CHM13v2.0
Adgre1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391757,665,650 - 57,790,527 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1757,665,691 - 57,790,527 (+)EnsemblGRCm39 Ensembl
GRCm381757,358,581 - 57,483,529 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1757,358,691 - 57,483,527 (+)EnsemblGRCm38mm10GRCm38
MGSCv371757,498,109 - 57,622,952 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361757,044,026 - 57,168,862 (+)NCBIMGSCv36mm8
Celera1761,708,492 - 61,834,039 (+)NCBICelera
Cytogenetic Map17DNCBI
cM Map1729.8NCBI
Adgre1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554952,601,413 - 2,674,738 (-)NCBIChiLan1.0ChiLan1.0
ADGRE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22011,298,860 - 11,350,817 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11910,524,065 - 10,577,171 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0195,918,097 - 5,970,069 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1196,838,787 - 6,891,292 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl196,838,787 - 6,891,292 (+)Ensemblpanpan1.1panPan2
ADGRE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12053,404,096 - 53,465,267 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2053,404,457 - 53,465,243 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2053,154,280 - 53,214,040 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02054,058,184 - 54,120,272 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2054,058,548 - 54,120,242 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12053,126,876 - 53,187,421 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02053,574,601 - 53,635,395 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02053,803,931 - 53,864,739 (-)NCBIUU_Cfam_GSD_1.0
Adgre1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118213,665,444 - 213,704,306 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365884,138,872 - 4,167,069 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365884,127,497 - 4,169,323 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADGRE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1272,217,036 - 72,305,925 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2272,699,549 - 72,739,448 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADGRE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.166,444,621 - 6,499,438 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660811,452,580 - 1,539,330 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adgre1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248283,930,483 - 3,981,966 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Adgre1
1425 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:44
Count of miRNA genes:37
Interacting mature miRNAs:42
Transcripts:ENSRNOT00000073926
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9114209783Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat

Markers in Region
RH139937  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.292,397,687 - 2,397,876 (-)MAPPERmRatBN7.2
Rnor_6.099,432,012 - 9,432,200NCBIRnor6.0
Rnor_5.098,434,459 - 8,434,647UniSTSRnor5.0
Celera96,129,071 - 6,129,259UniSTS
Cytogenetic Map9q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 21 14 16 14 1 6 11 8
Low 3 34 36 27 3 27 8 11 67 29 28 3 8
Below cutoff 4 6 2

Sequence


Ensembl Acc Id: ENSRNOT00000073926   ⟹   ENSRNOP00000067220
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl92,242,474 - 2,398,000 (+)Ensembl
Rnor_6.0 Ensembl99,431,860 - 9,585,865 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105310   ⟹   ENSRNOP00000084080
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl92,242,474 - 2,398,000 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107295   ⟹   ENSRNOP00000080360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl92,254,541 - 2,395,812 (+)Ensembl
RefSeq Acc Id: NM_001007557   ⟹   NP_001007558
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr892,329,440 - 2,484,959 (+)NCBI
mRatBN7.292,242,476 - 2,398,000 (+)NCBI
Rnor_6.099,431,888 - 9,585,852 (-)NCBI
Rnor_5.098,434,335 - 8,593,088 (-)NCBI
Celera96,128,947 - 6,277,689 (-)RGD
Sequence:
RefSeq Acc Id: XM_006244280   ⟹   XP_006244342
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr892,329,398 - 2,484,955 (+)NCBI
mRatBN7.292,242,480 - 2,398,000 (+)NCBI
Rnor_6.099,431,888 - 9,585,883 (-)NCBI
Rnor_5.098,434,335 - 8,593,088 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083467   ⟹   XP_038939395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr892,329,437 - 2,484,955 (+)NCBI
mRatBN7.292,242,481 - 2,398,000 (+)NCBI
RefSeq Acc Id: XM_039083468   ⟹   XP_038939396
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr892,329,398 - 2,468,451 (+)NCBI
mRatBN7.292,242,481 - 2,371,576 (+)NCBI
RefSeq Acc Id: NP_001007558   ⟸   NM_001007557
- Peptide Label: precursor
- UniProtKB: Q5Y4N8 (UniProtKB/Swiss-Prot),   A6KQQ5 (UniProtKB/TrEMBL),   A0A8I5ZPM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244342   ⟸   XM_006244280
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZYF2 (UniProtKB/TrEMBL),   A0A8I5ZPM3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000067220   ⟸   ENSRNOT00000073926
RefSeq Acc Id: XP_038939395   ⟸   XM_039083467
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZPM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939396   ⟸   XM_039083468
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000080360   ⟸   ENSRNOT00000107295
Ensembl Acc Id: ENSRNOP00000084080   ⟸   ENSRNOT00000105310
Protein Domains
EGF-like   G-protein coupled receptors family 2 profile   GAIN-B

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5Y4N8-F1-model_v2 AlphaFold Q5Y4N8 1-932 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696431
Promoter ID:EPDNEW_R6955
Type:multiple initiation site
Name:Adgre1_1
Description:adhesion G protein-coupled receptor E1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.099,585,843 - 9,585,903EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359214 AgrOrtholog
BioCyc Gene G2FUF-28478 BioCyc
Ensembl Genes ENSRNOG00000046254 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000073926.3 UniProtKB/Swiss-Prot
  ENSRNOT00000105310.1 UniProtKB/TrEMBL
  ENSRNOT00000107295.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.220.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GAIN_dom_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GAIN_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_EMR1-like_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_secretin-like_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NOTCH1_EGF-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:316137 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 316137 ENTREZGENE
PANTHER ADHESION G PROTEIN-COUPLED RECEPTOR E1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADHESION G-PROTEIN COUPLED RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Adgre1 PhenoGen
PRINTS EMR1HORMONER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRSECRETIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046254 RatGTEx
SMART EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57184 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZPM3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZYF2 ENTREZGENE, UniProtKB/TrEMBL
  A6KQQ5 ENTREZGENE, UniProtKB/TrEMBL
  AGRE1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-03-16 Adgre1  adhesion G protein-coupled receptor E1  Emr1  EGF-like module containing, mucin-like, hormone receptor-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-25 Emr1  EGF-like module containing, mucin-like, hormone receptor-like 1  Emr1  EGF-like module containing, mucin-like, hormone receptor-like sequence 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Emr1  EGF-like module containing, mucin-like, hormone receptor-like sequence 1      Symbol and Name status set to approved 1299863 APPROVED
2005-07-29 Emr1  EGF-like module containing, mucin-like, hormone receptor-like sequence 1      Symbol and Name status set to provisional 70820 PROVISIONAL