Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Arid5a | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ARID5A mRNA] | CTD | PMID:31150632 | Arid5a | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of ARID5A mRNA | CTD | PMID:22206623 | Arid5a | Rat | 15-acetyldeoxynivalenol | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | 15-acetyldeoxynivalenol results in increased expression of ARID5A mRNA | CTD | PMID:23792671 | Arid5a | Rat | 17beta-estradiol | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | ARID5A protein inhibits the reaction [Estradiol results in increased activity of ESR1 protein] | CTD | PMID:15941852 | Arid5a | Rat | 17beta-estradiol | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Estradiol results in increased expression of ARID5A mRNA | CTD | PMID:31614463 | Arid5a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Arid5a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARID5A mRNA | CTD | PMID:21570461 and PMID:26377647 | Arid5a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ARID5A mRNA | CTD | PMID:33387578 and PMID:34747641 | Arid5a | Rat | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | tetrabromobisphenol A results in increased expression of ARID5A mRNA | CTD | PMID:25172293 | Arid5a | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ARID5A mRNA | CTD | PMID:28628672 | Arid5a | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ARID5A mRNA | CTD | PMID:28628672 | Arid5a | Rat | 4-hydroxynon-2-enal | decreases expression | ISO | Arid5a (Mus musculus) | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of ARID5A mRNA | CTD | PMID:19191707 | Arid5a | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Fenretinide results in increased expression of ARID5A mRNA | CTD | PMID:28973697 | Arid5a | Rat | acrolein | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ARID5A mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ARID5A mRNA | CTD | PMID:32699268 | Arid5a | Rat | acrylamide | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Acrylamide results in increased expression of ARID5A mRNA | CTD | PMID:30807115 | Arid5a | Rat | afimoxifene | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | ARID5A protein inhibits the reaction [afimoxifene results in increased activity of ESR1 protein] | CTD | PMID:15941852 | Arid5a | Rat | aflatoxin B1 | decreases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of ARID5A mRNA | CTD | PMID:22100608 | Arid5a | Rat | alpha-pinene | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ARID5A mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ARID5A mRNA | CTD | PMID:32699268 | Arid5a | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of ARID5A mRNA | CTD | PMID:35163327 | Arid5a | Rat | amiodarone | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Amiodarone results in increased expression of ARID5A mRNA | CTD | PMID:19774075 | Arid5a | Rat | aristolochic acid A | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of ARID5A mRNA | CTD | PMID:33212167 | Arid5a | Rat | atrazine | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Atrazine results in increased expression of ARID5A mRNA | CTD | PMID:22378314 | Arid5a | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of ARID5A gene | CTD | PMID:35440735 | Arid5a | Rat | benzo[a]pyrene | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of ARID5A mRNA | CTD | PMID:21569818 and PMID:22228805 | Arid5a | Rat | benzo[a]pyrene | decreases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ARID5A mRNA | CTD | PMID:32234424 | Arid5a | Rat | benzo[a]pyrene | affects methylation | ISO | ARID5A (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ARID5A promoter | CTD | PMID:27901495 | Arid5a | Rat | benzo[a]pyrene | decreases expression | ISO | Arid5a (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ARID5A mRNA | CTD | PMID:25908611 | Arid5a | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ARID5A mRNA | CTD | PMID:25181051 | Arid5a | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ARID5A mRNA | CTD | PMID:30816183 and PMID:32528016 | Arid5a | Rat | bisphenol A | decreases expression | ISO | Arid5a (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ARID5A mRNA | CTD | PMID:25594700 and PMID:30951980 | Arid5a | Rat | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of ARID5A mRNA | CTD | PMID:32479839 | Arid5a | Rat | butanal | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of ARID5A mRNA | CTD | PMID:26079696 | Arid5a | Rat | cadmium dichloride | decreases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of ARID5A mRNA | CTD | PMID:38568856 | Arid5a | Rat | caffeine | increases phosphorylation | ISO | ARID5A (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of ARID5A protein | CTD | PMID:35688186 | Arid5a | Rat | carbon nanotube | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | Arid5a | Rat | carbon nanotube | affects expression | ISO | Arid5a (Mus musculus) | 6480464 | Nanotubes and Carbon affects the expression of ARID5A mRNA | CTD | PMID:31978390 | Arid5a | Rat | cefaloridine | increases expression | EXP | | 6480464 | Cephaloridine results in increased expression of ARID5A mRNA | CTD | PMID:18500788 | Arid5a | Rat | chlorpyrifos | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of ARID5A mRNA | CTD | PMID:34289071 | Arid5a | Rat | dexamethasone | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ARID5A mRNA | CTD | PMID:28628672 | Arid5a | Rat | Dibutyl phosphate | affects expression | ISO | ARID5A (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of ARID5A mRNA | CTD | PMID:37042841 | Arid5a | Rat | diclofenac | decreases expression | ISO | Arid5a (Mus musculus) | 6480464 | Diclofenac results in decreased expression of ARID5A mRNA | CTD | PMID:35537566 | Arid5a | Rat | dioxygen | multiple interactions | ISO | Arid5a (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ARID5A mRNA | CTD | PMID:30529165 | Arid5a | Rat | disodium selenite | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of ARID5A mRNA | CTD | PMID:18175754 | Arid5a | Rat | doxorubicin | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Doxorubicin results in increased expression of ARID5A mRNA | CTD | PMID:36227756 | Arid5a | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of ARID5A mRNA | CTD | PMID:29391264 | Arid5a | Rat | fluoranthene | multiple interactions | ISO | Arid5a (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of ARID5A mRNA | CTD | PMID:28329830 | Arid5a | Rat | FR900359 | increases phosphorylation | ISO | ARID5A (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of ARID5A protein | CTD | PMID:37730182 | Arid5a | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of ARID5A mRNA | CTD | PMID:33387578 | Arid5a | Rat | graphite | affects expression | EXP | | 6480464 | Graphite affects the expression of ARID5A mRNA | CTD | PMID:29933104 | Arid5a | Rat | indometacin | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ARID5A mRNA | CTD | PMID:28628672 | Arid5a | Rat | melphalan | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Melphalan results in increased expression of ARID5A mRNA | CTD | PMID:22363485 | Arid5a | Rat | menadione | affects expression | ISO | ARID5A (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of ARID5A mRNA | CTD | PMID:20044591 | Arid5a | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of ARID5A gene | CTD | PMID:35440735 | Arid5a | Rat | methylmercury chloride | increases expression | EXP | | 6480464 | methylmercuric chloride results in increased expression of ARID5A mRNA | CTD | PMID:31378766 | Arid5a | Rat | Muraglitazar | decreases expression | EXP | | 6480464 | muraglitazar results in decreased expression of ARID5A mRNA | CTD | PMID:21515302 | Arid5a | Rat | N-methyl-4-phenylpyridinium | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of ARID5A mRNA | CTD | PMID:24810058 | Arid5a | Rat | naphthalene | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | naphthalene results in increased expression of ARID5A mRNA | CTD | PMID:18978301 | Arid5a | Rat | nickel atom | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Nickel results in increased expression of ARID5A mRNA | CTD | PMID:24768652 and PMID:25583101 | Arid5a | Rat | ozone | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ARID5A mRNA more ... | CTD | PMID:32699268 | Arid5a | Rat | paracetamol | affects expression | ISO | Arid5a (Mus musculus) | 6480464 | Acetaminophen affects the expression of ARID5A mRNA | CTD | PMID:17562736 | Arid5a | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ARID5A mRNA | CTD | PMID:33387578 | Arid5a | Rat | pentanal | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | pentanal results in increased expression of ARID5A mRNA | CTD | PMID:26079696 | Arid5a | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of ARID5A mRNA | CTD | PMID:35163327 | Arid5a | Rat | phenobarbital | multiple interactions | ISO | Arid5a (Mus musculus) | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of ARID5A mRNA] | CTD | PMID:19482888 | Arid5a | Rat | phenobarbital | affects expression | ISO | ARID5A (Homo sapiens) | 6480464 | Phenobarbital affects the expression of ARID5A mRNA | CTD | PMID:19159669 | Arid5a | Rat | phenobarbital | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Phenobarbital results in increased expression of ARID5A mRNA | CTD | PMID:19482888 | Arid5a | Rat | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of ARID5A mRNA | CTD | PMID:28903501 | Arid5a | Rat | raloxifene | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | ARID5A protein inhibits the reaction [Raloxifene Hydrochloride results in increased activity of ESR1 protein] | CTD | PMID:15941852 | Arid5a | Rat | silicon dioxide | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of ARID5A mRNA | CTD | PMID:25895662 | Arid5a | Rat | silicon dioxide | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of ARID5A mRNA | CTD | PMID:19073995 and PMID:33720480 | Arid5a | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of ARID5A mRNA | CTD | PMID:19281266 | Arid5a | Rat | sunitinib | decreases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of ARID5A mRNA | CTD | PMID:31533062 | Arid5a | Rat | Tesaglitazar | decreases expression | EXP | | 6480464 | tesaglitazar results in decreased expression of ARID5A mRNA | CTD | PMID:21515302 | Arid5a | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of ARID5A mRNA | CTD | PMID:31150632 | Arid5a | Rat | tetrachloromethane | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of ARID5A mRNA | CTD | PMID:31919559 | Arid5a | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ARID5A mRNA] | CTD | PMID:31150632 | Arid5a | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ARID5A mRNA | CTD | PMID:34492290 | Arid5a | Rat | thiram | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Thiram results in increased expression of ARID5A mRNA | CTD | PMID:38568856 | Arid5a | Rat | titanium dioxide | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | titanium dioxide results in increased expression of ARID5A mRNA | CTD | PMID:27760801 | Arid5a | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of ARID5A mRNA | CTD | PMID:33387578 | Arid5a | Rat | triphenyl phosphate | affects expression | ISO | ARID5A (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of ARID5A mRNA | CTD | PMID:37042841 | Arid5a | Rat | Triptolide | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | triptolide results in increased expression of ARID5A mRNA | CTD | PMID:32835833 | Arid5a | Rat | triptonide | affects expression | ISO | Arid5a (Mus musculus) | 6480464 | triptonide affects the expression of ARID5A mRNA | CTD | PMID:33045310 | Arid5a | Rat | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of ARID5A mRNA | CTD | PMID:21515302 | Arid5a | Rat | trovafloxacin | decreases expression | ISO | Arid5a (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of ARID5A mRNA | CTD | PMID:35537566 | Arid5a | Rat | tungsten | decreases expression | ISO | Arid5a (Mus musculus) | 6480464 | Tungsten results in decreased expression of ARID5A mRNA | CTD | PMID:30912803 | Arid5a | Rat | valproic acid | increases methylation | ISO | ARID5A (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of ARID5A gene | CTD | PMID:29154799 | Arid5a | Rat | valproic acid | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Valproic Acid results in increased expression of ARID5A mRNA | CTD | PMID:21427059 | Arid5a | Rat | valproic acid | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ARID5A mRNA | CTD | PMID:29154799 | |