Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ubr2 | Rat | (-)-demecolcine | increases expression | ISO | UBR2 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of UBR2 mRNA | CTD | PMID:23649840 | Ubr2 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | UBR2 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of UBR2 mRNA | CTD | PMID:22079256 | Ubr2 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Ubr2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of UBR2 mRNA | CTD | PMID:36331819 | Ubr2 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Ubr2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of UBR2 mRNA | CTD | PMID:22206623 | Ubr2 | Rat | 1-naphthyl isothiocyanate | decreases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of UBR2 mRNA | CTD | PMID:30723492 | Ubr2 | Rat | 17beta-estradiol | multiple interactions | ISO | UBR2 (Homo sapiens) | 6480464 | [Estradiol co-treated with Norethindrone Acetate] results in increased expression of UBR2 mRNA | CTD | PMID:22217510 | Ubr2 | Rat | 1H-pyrazole | decreases expression | ISO | Ubr2 (Mus musculus) | 6480464 | pyrazole results in decreased expression of UBR2 mRNA | CTD | PMID:17945193 | Ubr2 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Ubr2 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | Ubr2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | UBR2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of UBR2 mRNA | CTD | PMID:19684285 | Ubr2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of UBR2 mRNA | CTD | PMID:33387578 | Ubr2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Ubr2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of UBR2 mRNA | CTD | PMID:19684285 | Ubr2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ubr2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of UBR2 mRNA | CTD | PMID:19684285 | Ubr2 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | Ubr2 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Ubr2 (Mus musculus) | 6480464 | bisphenol S affects the methylation of UBR2 gene | CTD | PMID:31683443 | Ubr2 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of UBR2 mRNA | CTD | PMID:30047161 | Ubr2 | Rat | acrylamide | increases expression | ISO | UBR2 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of UBR2 mRNA | CTD | PMID:32763439 | Ubr2 | Rat | aflatoxin B1 | increases methylation | ISO | UBR2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of UBR2 intron | CTD | PMID:30157460 | Ubr2 | Rat | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of UBR2 mRNA | CTD | PMID:33354967 | Ubr2 | Rat | all-trans-retinoic acid | increases expression | ISO | UBR2 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of UBR2 mRNA | CTD | PMID:33167477 | Ubr2 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of UBR2 mRNA | CTD | PMID:30047161 | Ubr2 | Rat | arsane | affects methylation | ISO | UBR2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of UBR2 gene | CTD | PMID:25304211 | Ubr2 | Rat | arsenic atom | affects methylation | ISO | UBR2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of UBR2 gene | CTD | PMID:25304211 | Ubr2 | Rat | arsenite(3-) | multiple interactions | ISO | UBR2 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to UBR2 mRNA] | CTD | PMID:32406909 | Ubr2 | Rat | atrazine | increases expression | ISO | UBR2 (Homo sapiens) | 6480464 | Atrazine results in increased expression of UBR2 mRNA | CTD | PMID:22378314 | Ubr2 | Rat | benzo[a]pyrene | increases expression | ISO | Ubr2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of UBR2 mRNA | CTD | PMID:19770486 | Ubr2 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | UBR2 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | Ubr2 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Ubr2 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of UBR2 mRNA | CTD | PMID:21318169 | Ubr2 | Rat | bisphenol A | decreases expression | ISO | Ubr2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of UBR2 mRNA | CTD | PMID:26063408 | Ubr2 | Rat | bisphenol A | increases expression | ISO | Ubr2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of UBR2 mRNA | CTD | PMID:33221593 | Ubr2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of UBR2 mRNA | CTD | PMID:30816183 and PMID:32528016 | Ubr2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of UBR2 mRNA | CTD | PMID:25181051 more ... | Ubr2 | Rat | Bisphenol A diglycidyl ether | affects splicing | ISO | Ubr2 (Mus musculus) | 6480464 | 2 and 2-bis(4-glycidyloxyphenyl)propane affects the splicing of UBR2 mRNA | CTD | PMID:36464114 | Ubr2 | Rat | cadmium dichloride | decreases expression | ISO | UBR2 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of UBR2 mRNA | CTD | PMID:38568856 | Ubr2 | Rat | caffeine | decreases phosphorylation | ISO | UBR2 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of UBR2 protein | CTD | PMID:35688186 | Ubr2 | Rat | chlorpyrifos | decreases expression | ISO | Ubr2 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of UBR2 mRNA | CTD | PMID:37019170 | Ubr2 | Rat | choline | multiple interactions | ISO | Ubr2 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of UBR2 gene | CTD | PMID:20938992 | Ubr2 | Rat | clofibrate | decreases expression | ISO | Ubr2 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of UBR2 mRNA | CTD | PMID:23811191 | Ubr2 | Rat | cobalt dichloride | increases expression | ISO | UBR2 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of UBR2 mRNA | CTD | PMID:19320972 and PMID:19376846 | Ubr2 | Rat | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of UBR2 mRNA | CTD | PMID:24386269 | Ubr2 | Rat | copper(II) sulfate | increases expression | ISO | UBR2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of UBR2 mRNA | CTD | PMID:19549813 | Ubr2 | Rat | coumarin | increases phosphorylation | ISO | UBR2 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of UBR2 protein | CTD | PMID:35688186 | Ubr2 | Rat | decabromodiphenyl ether | decreases expression | EXP | | 6480464 | decabromobiphenyl ether results in decreased expression of UBR2 mRNA | CTD | PMID:23640034 | Ubr2 | Rat | Dibutyl phosphate | affects expression | ISO | UBR2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of UBR2 mRNA | CTD | PMID:37042841 | Ubr2 | Rat | endosulfan | increases expression | ISO | UBR2 (Homo sapiens) | 6480464 | Endosulfan results in increased expression of UBR2 mRNA | CTD | PMID:26615145 | Ubr2 | Rat | epoxiconazole | decreases expression | ISO | Ubr2 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of UBR2 mRNA | CTD | PMID:35436446 | Ubr2 | Rat | ethyl methanesulfonate | increases expression | ISO | UBR2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of UBR2 mRNA | CTD | PMID:23649840 | Ubr2 | Rat | fenofibrate | multiple interactions | ISO | Ubr2 (Mus musculus) | 6480464 | [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of UBR2 mRNA | CTD | PMID:21318169 | Ubr2 | Rat | fenofibrate | increases expression | ISO | Ubr2 (Mus musculus) | 6480464 | Fenofibrate results in increased expression of UBR2 mRNA | CTD | PMID:21318169 | Ubr2 | Rat | folic acid | multiple interactions | ISO | Ubr2 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of UBR2 gene | CTD | PMID:20938992 | Ubr2 | Rat | folic acid | decreases expression | ISO | Ubr2 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of UBR2 mRNA | CTD | PMID:25629700 | Ubr2 | Rat | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of UBR2 mRNA | CTD | PMID:24136188 | Ubr2 | Rat | isoprenaline | increases expression | ISO | Ubr2 (Mus musculus) | 6480464 | Isoproterenol results in increased expression of UBR2 mRNA | CTD | PMID:20003209 | Ubr2 | Rat | L-methionine | multiple interactions | ISO | Ubr2 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of UBR2 gene | CTD | PMID:20938992 | Ubr2 | Rat | methamphetamine | increases expression | ISO | Ubr2 (Mus musculus) | 6480464 | Methamphetamine results in increased expression of UBR2 mRNA | CTD | PMID:36914120 | Ubr2 | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of UBR2 mRNA | CTD | PMID:30047161 | Ubr2 | Rat | methyl methanesulfonate | increases expression | ISO | UBR2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of UBR2 mRNA | CTD | PMID:23649840 | Ubr2 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of UBR2 mRNA | CTD | PMID:25729387 | Ubr2 | Rat | paracetamol | decreases expression | ISO | UBR2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of UBR2 mRNA | CTD | PMID:21420995 | Ubr2 | Rat | paracetamol | affects expression | ISO | Ubr2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of UBR2 mRNA | CTD | PMID:17562736 | Ubr2 | Rat | pentane-2,3-dione | increases expression | EXP | | 6480464 | 2 and 3-pentanedione results in increased expression of UBR2 mRNA | CTD | PMID:25710175 | Ubr2 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Ubr2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of UBR2 mRNA | CTD | PMID:36331819 | Ubr2 | Rat | phlorizin | increases expression | ISO | Ubr2 (Mus musculus) | 6480464 | Phlorhizin results in increased expression of UBR2 mRNA | CTD | PMID:22538082 | Ubr2 | Rat | pirinixic acid | multiple interactions | ISO | Ubr2 (Mus musculus) | 6480464 | PPARA protein affects the reaction [pirinixic acid results in decreased expression of UBR2 mRNA] | CTD | PMID:21318169 | Ubr2 | Rat | pirinixic acid | decreases expression | ISO | Ubr2 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of UBR2 mRNA | CTD | PMID:21318169 and PMID:23811191 | Ubr2 | Rat | potassium chromate | multiple interactions | ISO | UBR2 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of UBR2 mRNA | CTD | PMID:22079256 | Ubr2 | Rat | potassium chromate | decreases expression | ISO | UBR2 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of UBR2 mRNA | CTD | PMID:22079256 | Ubr2 | Rat | propiconazole | decreases expression | ISO | Ubr2 (Mus musculus) | 6480464 | propiconazole results in decreased expression of UBR2 mRNA | CTD | PMID:21278054 | Ubr2 | Rat | resveratrol | multiple interactions | ISO | UBR2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of UBR2 mRNA | CTD | PMID:23557933 | Ubr2 | Rat | silver atom | increases expression | ISO | UBR2 (Homo sapiens) | 6480464 | Silver results in increased expression of UBR2 mRNA | CTD | PMID:26551752 | Ubr2 | Rat | silver(0) | increases expression | ISO | UBR2 (Homo sapiens) | 6480464 | Silver results in increased expression of UBR2 mRNA | CTD | PMID:26551752 | Ubr2 | Rat | sodium arsenite | increases expression | ISO | UBR2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of UBR2 mRNA | CTD | PMID:38568856 | Ubr2 | Rat | sodium arsenite | multiple interactions | ISO | UBR2 (Homo sapiens) | 6480464 | sodium arsenite promotes the reaction [UBR2 protein binds to CAPRIN1 protein] | CTD | PMID:33939924 | Ubr2 | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of UBR2 mRNA | CTD | PMID:30047161 | Ubr2 | Rat | thapsigargin | increases expression | ISO | Ubr2 (Mus musculus) | 6480464 | Thapsigargin results in increased expression of UBR2 protein | CTD | PMID:24648495 | Ubr2 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of UBR2 mRNA | CTD | PMID:34492290 | Ubr2 | Rat | titanium dioxide | increases expression | ISO | Ubr2 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of UBR2 mRNA | CTD | PMID:23557971 | Ubr2 | Rat | titanium dioxide | decreases methylation | ISO | Ubr2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of UBR2 gene and titanium dioxide results in decreased methylation of UBR2 promoter | CTD | PMID:35295148 | Ubr2 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of UBR2 mRNA | CTD | PMID:25729387 | Ubr2 | Rat | triphenyl phosphate | affects expression | ISO | UBR2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of UBR2 mRNA | CTD | PMID:37042841 | Ubr2 | Rat | tungsten | decreases expression | ISO | Ubr2 (Mus musculus) | 6480464 | Tungsten results in decreased expression of UBR2 mRNA | CTD | PMID:30912803 | Ubr2 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of UBR2 mRNA | CTD | PMID:23034163 | Ubr2 | Rat | vinclozolin | decreases methylation | EXP | | 6480464 | vinclozolin results in decreased methylation of UBR2 gene | CTD | PMID:31682807 | Ubr2 | Rat | vincristine | increases expression | ISO | UBR2 (Homo sapiens) | 6480464 | Vincristine results in increased expression of UBR2 mRNA | CTD | PMID:23649840 | Ubr2 | Rat | zinc atom | multiple interactions | ISO | UBR2 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of UBR2 mRNA | CTD | PMID:18593933 | Ubr2 | Rat | zinc(0) | multiple interactions | ISO | UBR2 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of UBR2 mRNA | CTD | PMID:18593933 | |