Sgo1 (shugoshin 1) - Rat Genome Database

Name: Sgo1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Sgo1 (shugoshin 1) Rattus norvegicus

Analyze

Symbol:

Sgo1

Name:

shugoshin 1

RGD ID:

1593238

Description:

Predicted to enable kinase binding activity. Predicted to be involved in attachment of spindle microtubules to kinetochore and mitotic sister chromatid cohesion, centromeric. Predicted to act upstream of or within centriole-centriole cohesion and meiotic chromosome segregation. Predicted to be located in several cellular components, including condensed chromosome, centromeric region; microtubule cytoskeleton; and nucleoplasm. Predicted to colocalize with kinetochore. Human ortholog(s) of this gene implicated in chronic atrial and intestinal dysrhythmia. Orthologous to human SGO1 (shugoshin 1); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC363174; Sgol1; shugoshin-like 1; shugoshin-like 1 (S. pombe); similar to shugoshin-like 1

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SGO1 (shugoshin 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Sgo1 (shugoshin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sgo1 (shugoshin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SGO1 (shugoshin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SGO1 (shugoshin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sgo1 (shugoshin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SGO1 (shugoshin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SGO1 (shugoshin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sgo1 (shugoshin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Sgo1 (shugoshin 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SGO1 (shugoshin 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	sgo1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	sgo1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	6,672,109 - 6,687,908 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	6,672,123 - 6,687,805 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	7,824,399 - 7,840,180 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	12,981,935 - 12,997,712 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	12,139,917 - 12,155,692 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	4,420,158 - 4,435,939 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	4,421,069 - 4,436,601 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	3,458,754 - 3,474,509 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	863,665 - 876,405	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Cytogenetic Map	9	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cardiac Arrhythmias (ISO)

chronic atrial and intestinal dysrhythmia (ISO)

Chronobiology Disorders (ISO)

genetic disease (ISO)

intestinal disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-butoxyethanol (ISO)

2-methylcholine (ISO)

3-methylcholanthrene (ISO)

4,4'-sulfonyldiphenol (EXP)

4-hydroxynon-2-enal (ISO)

4-hydroxyphenyl retinamide (ISO)

acrylamide (ISO)

all-trans-retinoic acid (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

clofibrate (ISO)

coumestrol (ISO)

dibenz[a,h]anthracene (ISO)

dibutyl phthalate (ISO)

dorsomorphin (ISO)

Enterolactone (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

L-methionine (ISO)

lucanthone (ISO)

methyl methanesulfonate (ISO)

N-Nitrosopyrrolidine (ISO)

ozone (ISO)

paracetamol (ISO)

paraquat (ISO)

PCB138 (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

propanal (ISO)

resveratrol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tacrolimus hydrate (ISO)

tamoxifen (ISO)

testosterone (EXP,ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (ISO)

trimellitic anhydride (ISO)

troglitazone (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

zaragozic acid A (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

attachment of spindle microtubules to kinetochore (ISO)

cell division (IEA)

centriole-centriole cohesion (ISO)

chromosome segregation (ISO)

meiotic chromosome segregation (ISO)

mitotic sister chromatid cohesion, centromeric (ISO)

Cellular Component

centrosome (ISO)

chromosome, centromeric region (ISO)

condensed chromosome, centromeric region (ISO)

cytosol (ISO)

kinetochore (ISO)

nucleoplasm (ISO)

nucleus (IEA)

spindle pole (ISO)

Molecular Function

kinase binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:16580887	PMID:16582621	PMID:16682347	PMID:17617734	PMID:17621308	PMID:18084284	PMID:18331714	PMID:19465021	PMID:24055156	PMID:24157919	PMID:33953173

Genomics

Comparative Map Data

Sgo1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	6,672,109 - 6,687,908 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	6,672,123 - 6,687,805 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	7,824,399 - 7,840,180 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	12,981,935 - 12,997,712 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	12,139,917 - 12,155,692 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	4,420,158 - 4,435,939 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	4,421,069 - 4,436,601 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	3,458,754 - 3,474,509 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	863,665 - 876,405	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Cytogenetic Map	9	q11	NCBI

SGO1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	20,160,593 - 20,186,886 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	20,160,593 - 20,186,206 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	20,202,085 - 20,227,698 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	20,177,087 - 20,202,687 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	20,177,088 - 20,202,687	NCBI
Celera	3	20,142,704 - 20,168,302 (-)	NCBI		Celera
Cytogenetic Map	3	p24.3	NCBI
HuRef	3	20,141,996 - 20,167,635 (-)	NCBI		HuRef
CHM1_1	3	20,153,920 - 20,179,582 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	20,164,579 - 20,190,864 (-)	NCBI		T2T-CHM13v2.0

Sgo1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	53,981,814 - 53,996,432 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	53,981,814 - 53,996,361 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	53,674,786 - 53,691,331 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	53,674,786 - 53,689,333 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	53,814,112 - 53,828,640 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	53,140,989 - 53,154,241 (-)	NCBI		MGSCv36	mm8
Celera	17	57,116,694 - 57,131,231 (-)	NCBI		Celera
Cytogenetic Map	17	C	NCBI
cM Map	17	27.92	NCBI

Sgo1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955430	12,198,397 - 12,213,201 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955430	12,200,601 - 12,216,845 (-)	NCBI	ChiLan1.0	ChiLan1.0

SGO1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	3	20,132,008 - 20,148,703 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	20,079,671 - 20,096,390 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	20,409,002 - 20,424,940 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

SGO1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	23,145,187 - 23,160,581 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	23,144,816 - 23,315,597 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	23,168,474 - 23,183,459 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	23,629,839 - 23,644,831 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	23,632,352 - 23,643,827 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	23,342,031 - 23,357,256 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	23,407,492 - 23,422,465 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	23,653,722 - 23,668,705 (+)	NCBI		UU_Cfam_GSD_1.0

Sgo1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	179,285,311 - 179,301,037 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936473	12,425,780 - 12,436,899 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936473	12,425,026 - 12,436,900 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SGO1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	7,137,896 - 7,153,170 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	7,137,891 - 7,153,202 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	8,091,298 - 8,106,584 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SGO1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	64,901,974 - 64,917,338 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	64,901,668 - 64,917,324 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	37,921,295 - 37,936,698 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sgo1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624821	5,498,386 - 5,511,796 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624821	5,497,620 - 5,514,661 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Sgo1
72 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	128
Count of miRNA genes:	116
Interacting mature miRNAs:	119
Transcripts:	ENSRNOT00000065721
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10054141	Gmadr4	Adrenal mass QTL 4	2.45	0.0074	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	9	1	14209783	Rat
70226	Eae4	Experimental allergic encephalomyelitis QTL 4			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	9	1	25661317	Rat
9589055	Scfw5	Subcutaneous fat weight QTL 5	5.55	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	9	1	37999212	Rat
7411592	Foco8	Food consumption QTL 8	7.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	1	37999212	Rat
9589158	Gluco65	Glucose level QTL 65	6.82	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	9	1	37999212	Rat
1300124	Cm4	Cardiac mass QTL 4	3.55		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	9	1	40594091	Rat
1298088	Edpm11	Estrogen-dependent pituitary mass QTL 11	2.5		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	1	43718459	Rat
1641911	Alcrsp13	Alcohol response QTL 13			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	1	43718459	Rat
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
1331757	Cdexp1	CD45RC expression in CD8 T cells QTL 1	4.3		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	9	1024537	67509080	Rat
1354650	Despr5	Despair related QTL 5	4.01	0.0017	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	9	1254084	46254084	Rat
2303559	Gluco54	Glucose level QTL 54	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	1254084	46254084	Rat
1578675	Bss17	Bone structure and strength QTL 17	3.8		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	9	3368652	13533896	Rat
61425	Cia15	Collagen induced arthritis QTL 15	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	9	5109826	42921101	Rat
631211	Bw4	Body weight QTL4	5.31		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	9	5109826	50109826	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		10	24	18	9	18			26	14	27
Low	3	30	28	18	10	18	8	9	42	18	14	11	8
Below cutoff		3	5	5		5		2	6	3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001399344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399345	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008766789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084402	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474184	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000207	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000065721 ⟹ ENSRNOP00000061236

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	6,672,123 - 6,687,805 (-)	Ensembl
Rnor_6.0 Ensembl	9	4,421,069 - 4,436,601 (+)	Ensembl

RefSeq Acc Id:

NM_001399344 ⟹ NP_001386273

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	6,672,109 - 6,687,865 (-)	NCBI

RefSeq Acc Id:

NM_001399345 ⟹ NP_001386274

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	6,672,109 - 6,687,865 (-)	NCBI

RefSeq Acc Id:

XM_039084402 ⟹ XP_038940330

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	6,672,109 - 6,687,908 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001386273	(Get FASTA)	NCBI Sequence Viewer
	NP_001386274	(Get FASTA)	NCBI Sequence Viewer
	XP_038940330	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL82854	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

ENSRNOP00000061236 ⟸ ENSRNOT00000065721

RefSeq Acc Id:	XP_038940330 ⟸ XM_039084402
- Peptide Label:	isoform X2

RefSeq Acc Id:	NP_001386273 ⟸ NM_001399344
- UniProtKB:	D4A624 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386274 ⟸ NM_001399345
- UniProtKB:	D4A624 (UniProtKB/TrEMBL)

Protein Domains

Shugoshin C-terminal Shugoshin N-terminal coiled-coil

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A624-F1-model_v2	AlphaFold	D4A624	1-483	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1593238	AgrOrtholog
BioCyc Gene	G2FUF-28393	BioCyc
Ensembl Genes	ENSRNOG00000022499	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000061236	ENTREZGENE
	ENSRNOP00000061236.3	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000065721	ENTREZGENE
	ENSRNOT00000065721.3	UniProtKB/TrEMBL
Gene3D-CATH	Single helix bin	UniProtKB/TrEMBL
InterPro	Shugoshin	UniProtKB/TrEMBL
	Shugoshin_C	UniProtKB/TrEMBL
	Shugoshin_N	UniProtKB/TrEMBL
KEGG Report	rno:363174	UniProtKB/TrEMBL
NCBI Gene	363174	ENTREZGENE
PANTHER	PTHR21577	UniProtKB/TrEMBL
	PTHR21577:SF3	UniProtKB/TrEMBL
Pfam	Shugoshin_C	UniProtKB/TrEMBL
	Shugoshin_N	UniProtKB/TrEMBL
PhenoGen	Sgo1	PhenoGen
UniProt	D4A624	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-29	Sgo1	shugoshin 1	Sgol1	shugoshin-like 1 (S. pombe)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-05	Sgol1	shugoshin-like 1 (S. pombe)	LOC363174	similar to shugoshin-like 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC363174	similar to shugoshin-like 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM