Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nfya | Rat | (-)-demecolcine | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | Demecolcine results in increased expression of NFYA mRNA | CTD | PMID:23649840 | Nfya | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | NFYA (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of NFYA mRNA | CTD | PMID:22079256 | Nfya | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Nfya (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NFYA mRNA | CTD | PMID:22206623 | Nfya | Rat | 17beta-estradiol | multiple interactions | ISO | Nfya (Mus musculus) | 6480464 | [Polyphenols co-treated with Estradiol] results in decreased expression of NFYA mRNA | CTD | PMID:30077407 | Nfya | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Nfya (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Nfya | Rat | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Nfya (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Nfya | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Nfya (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NFYA mRNA | CTD | PMID:21570461 and PMID:24058054 | Nfya | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NFYA mRNA | CTD | PMID:33387578 | Nfya | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Nfya (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NFYA mRNA | CTD | PMID:37172768 | Nfya | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Nfya (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of NFYA mRNA | CTD | PMID:20188158 | Nfya | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Nfya (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of NFYA mRNA | CTD | PMID:26251327 | Nfya | Rat | 3-methylcholanthrene | multiple interactions | ISO | Nfya (Mus musculus) | 6480464 | Methylcholanthrene promotes the reaction [NFYA protein binds to KRAS exon] | CTD | PMID:16271038 | Nfya | Rat | 3-methylcholanthrene | increases activity | ISO | Nfya (Mus musculus) | 6480464 | Methylcholanthrene results in increased activity of NFYA protein | CTD | PMID:16271038 | Nfya | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Nfya (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of NFYA mRNA | CTD | PMID:18648102 | Nfya | Rat | 5-fluorouracil | multiple interactions | ISO | NFYA (Homo sapiens) | 6480464 | Fluorouracil inhibits the reaction [NFYA protein binds to UBE2C promoter] more ... | CTD | PMID:27129209 | Nfya | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of NFYA mRNA | CTD | PMID:24780913 | Nfya | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of NFYA mRNA | CTD | PMID:31881176 | Nfya | Rat | aflatoxin B1 | decreases methylation | ISO | NFYA (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of NFYA gene | CTD | PMID:27153756 | Nfya | Rat | Aflatoxin B2 alpha | decreases methylation | ISO | NFYA (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of NFYA intron | CTD | PMID:30157460 | Nfya | Rat | all-trans-retinoic acid | multiple interactions | ISO | NFYA (Homo sapiens) | 6480464 | [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of NFYA mRNA | CTD | PMID:16443354 | Nfya | Rat | all-trans-retinoic acid | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | Tretinoin results in increased expression of NFYA mRNA | CTD | PMID:23724009 | Nfya | Rat | arsane | affects methylation | ISO | NFYA (Homo sapiens) | 6480464 | Arsenic affects the methylation of NFYA gene | CTD | PMID:25304211 | Nfya | Rat | arsenic atom | affects methylation | ISO | NFYA (Homo sapiens) | 6480464 | Arsenic affects the methylation of NFYA gene | CTD | PMID:25304211 | Nfya | Rat | benzene | decreases expression | ISO | NFYA (Homo sapiens) | 6480464 | Benzene results in decreased expression of NFYA mRNA | CTD | PMID:21382456 | Nfya | Rat | benzo[a]pyrene | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of NFYA mRNA | CTD | PMID:20064835 and PMID:26238291 | Nfya | Rat | benzo[a]pyrene diol epoxide I | affects expression | ISO | NFYA (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:26238291 | Nfya | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NFYA mRNA | CTD | PMID:25181051 | Nfya | Rat | bisphenol A | decreases expression | ISO | Nfya (Mus musculus) | 6480464 | bisphenol A results in decreased expression of NFYA mRNA | CTD | PMID:35598803 | Nfya | Rat | cadmium dichloride | decreases expression | ISO | NFYA (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of NFYA mRNA | CTD | PMID:38568856 | Nfya | Rat | caffeine | decreases phosphorylation | ISO | NFYA (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of NFYA protein | CTD | PMID:35688186 | Nfya | Rat | CGP 52608 | multiple interactions | ISO | NFYA (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to NFYA gene] | CTD | PMID:28238834 | Nfya | Rat | chlordecone | increases expression | ISO | Nfya (Mus musculus) | 6480464 | Chlordecone results in increased expression of NFYA mRNA | CTD | PMID:29980752 | Nfya | Rat | cisplatin | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | Cisplatin results in increased expression of NFYA protein | CTD | PMID:20959455 | Nfya | Rat | cisplatin | multiple interactions | ISO | NFYA (Homo sapiens) | 6480464 | Cisplatin promotes the reaction [NFYA protein binds to TP63 protein] and TP63 protein alternative form promotes the reaction [Cisplatin results in increased expression of NFYA protein] | CTD | PMID:20959455 | Nfya | Rat | copper(II) sulfate | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of NFYA mRNA | CTD | PMID:19549813 | Nfya | Rat | crocidolite asbestos | decreases expression | ISO | Nfya (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of NFYA mRNA | CTD | PMID:29279043 | Nfya | Rat | curcumin | decreases expression | ISO | NFYA (Homo sapiens) | 6480464 | Curcumin results in decreased expression of NFYA mRNA | CTD | PMID:15713895 | Nfya | Rat | cyclosporin A | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of NFYA mRNA | CTD | PMID:25562108 | Nfya | Rat | deoxynivalenol | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | deoxynivalenol results in increased expression of NFYA protein | CTD | PMID:33890134 | Nfya | Rat | diazinon | increases methylation | ISO | NFYA (Homo sapiens) | 6480464 | Diazinon results in increased methylation of NFYA gene | CTD | PMID:22964155 | Nfya | Rat | Dibutyl phosphate | affects expression | ISO | NFYA (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of NFYA mRNA | CTD | PMID:37042841 | Nfya | Rat | enzyme inhibitor | multiple interactions | ISO | NFYA (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of NFYA protein | CTD | PMID:23301498 | Nfya | Rat | ethanol | affects expression | ISO | Nfya (Mus musculus) | 6480464 | Ethanol affects the expression of NFYA mRNA | CTD | PMID:30319688 | Nfya | Rat | ethanol | affects splicing | ISO | Nfya (Mus musculus) | 6480464 | Ethanol affects the splicing of NFYA mRNA | CTD | PMID:30319688 | Nfya | Rat | ethyl methanesulfonate | decreases expression | ISO | NFYA (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of NFYA mRNA | CTD | PMID:23649840 | Nfya | Rat | folic acid | multiple interactions | ISO | Nfya (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NFYA mRNA | CTD | PMID:22206623 | Nfya | Rat | folic acid | increases expression | ISO | Nfya (Mus musculus) | 6480464 | Folic Acid results in increased expression of NFYA mRNA | CTD | PMID:25629700 | Nfya | Rat | formaldehyde | decreases expression | ISO | NFYA (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of NFYA mRNA | CTD | PMID:20655997 | Nfya | Rat | FR900359 | increases phosphorylation | ISO | NFYA (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of NFYA protein | CTD | PMID:37730182 | Nfya | Rat | glycidyl methacrylate | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | glycidyl methacrylate results in increased expression of NFYA protein | CTD | PMID:36641056 | Nfya | Rat | hydrogen cyanide | decreases expression | ISO | Nfya (Mus musculus) | 6480464 | Hydrogen Cyanide results in decreased expression of NFYA mRNA | CTD | PMID:33914522 | Nfya | Rat | L-ascorbic acid | multiple interactions | ISO | NFYA (Homo sapiens) | 6480464 | [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of NFYA mRNA | CTD | PMID:16443354 | Nfya | Rat | lead diacetate | increases expression | ISO | Nfya (Mus musculus) | 6480464 | lead acetate results in increased expression of NFYA mRNA | CTD | PMID:21829687 | Nfya | Rat | leflunomide | decreases expression | ISO | NFYA (Homo sapiens) | 6480464 | leflunomide results in decreased expression of NFYA mRNA | CTD | PMID:28988120 | Nfya | Rat | methotrexate | affects expression | ISO | Nfya (Mus musculus) | 6480464 | Methotrexate affects the expression of NFYA mRNA | CTD | PMID:18502557 | Nfya | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of NFYA gene | CTD | PMID:35440735 | Nfya | Rat | methyl methanesulfonate | decreases expression | ISO | NFYA (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of NFYA mRNA | CTD | PMID:23649840 | Nfya | Rat | methylmercury chloride | decreases expression | ISO | NFYA (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of NFYA mRNA | CTD | PMID:28001369 | Nfya | Rat | mitomycin C | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | Mitomycin results in increased expression of NFYA mRNA | CTD | PMID:12760830 | Nfya | Rat | mitomycin C | affects response to substance | ISO | NFYA (Homo sapiens) | 6480464 | NFYA protein affects the susceptibility to Mitomycin | CTD | PMID:16217747 | Nfya | Rat | monosodium L-glutamate | multiple interactions | ISO | Nfya (Mus musculus) | 6480464 | [Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of NFYA mRNA | CTD | PMID:22078008 | Nfya | Rat | N-ethyl-N-nitrosourea | multiple interactions | ISO | Nfya (Mus musculus) | 6480464 | Ethylnitrosourea promotes the reaction [NFYA protein binds to KRAS exon] | CTD | PMID:16271038 | Nfya | Rat | N-ethyl-N-nitrosourea | increases activity | ISO | Nfya (Mus musculus) | 6480464 | Ethylnitrosourea results in increased activity of NFYA protein | CTD | PMID:16271038 | Nfya | Rat | N-methyl-N'-nitro-N-nitrosoguanidine | multiple interactions | ISO | NFYA (Homo sapiens) | 6480464 | Methylnitronitrosoguanidine promotes the reaction [NFYA protein binds to RRM2 promoter] and Methylnitronitrosoguanidine promotes the reaction [NFYA protein results in increased expression of RRM2 mRNA] | CTD | PMID:26921499 | Nfya | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of NFYA mRNA] | CTD | PMID:20360939 | Nfya | Rat | N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of NFYA mRNA | CTD | PMID:20360939 | Nfya | Rat | nickel dichloride | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | nickel chloride results in increased expression of NFYA mRNA | CTD | PMID:17547211 | Nfya | Rat | paracetamol | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of NFYA mRNA | CTD | PMID:21420995 | Nfya | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of NFYA mRNA | CTD | PMID:33387578 | Nfya | Rat | PCB138 | multiple interactions | ISO | Nfya (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Nfya | Rat | phenethyl caffeate | multiple interactions | EXP | | 6480464 | caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of NFYA mRNA] | CTD | PMID:20360939 | Nfya | Rat | phenol | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | Phenol results in increased expression of NFYA mRNA | CTD | PMID:17547211 | Nfya | Rat | pirinixic acid | multiple interactions | ISO | NFYA (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of NFYA mRNA | CTD | PMID:19710929 | Nfya | Rat | potassium chromate | multiple interactions | ISO | NFYA (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of NFYA mRNA | CTD | PMID:22079256 | Nfya | Rat | potassium chromate | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of NFYA mRNA | CTD | PMID:22079256 | Nfya | Rat | potassium cyanide | decreases expression | ISO | Nfya (Mus musculus) | 6480464 | Potassium Cyanide results in decreased expression of NFYA mRNA | CTD | PMID:33914522 | Nfya | Rat | quercetin | multiple interactions | ISO | NFYA (Homo sapiens) | 6480464 | Quercetin inhibits the reaction [NFYA protein binds to CCNB1 promoter] | CTD | PMID:19009557 | Nfya | Rat | rifampicin | decreases expression | ISO | NFYA (Homo sapiens) | 6480464 | Rifampin results in decreased expression of NFYA mRNA | CTD | PMID:24552687 | Nfya | Rat | sodium dodecyl sulfate | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | Sodium Dodecyl Sulfate results in increased expression of NFYA mRNA | CTD | PMID:31734321 | Nfya | Rat | sodium fluoride | decreases expression | ISO | Nfya (Mus musculus) | 6480464 | Sodium Fluoride results in decreased expression of NFYA mRNA | CTD | PMID:27862939 | Nfya | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of NFYA mRNA | CTD | PMID:34492290 | Nfya | Rat | titanium dioxide | decreases methylation | ISO | Nfya (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of NFYA gene | CTD | PMID:35295148 | Nfya | Rat | trabectedin | multiple interactions | ISO | Nfya (Mus musculus) | 6480464 | trabectedin affects the activity of [NFYA protein binds to NFYB protein binds to NFYC protein] | CTD | PMID:15961672 | Nfya | Rat | tungsten | decreases expression | ISO | Nfya (Mus musculus) | 6480464 | Tungsten results in decreased expression of NFYA mRNA | CTD | PMID:30912803 | Nfya | Rat | urethane | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | Urethane results in increased expression of NFYA mRNA | CTD | PMID:28818685 | Nfya | Rat | valproic acid | affects expression | ISO | NFYA (Homo sapiens) | 6480464 | Valproic Acid affects the expression of NFYA mRNA | CTD | PMID:25979313 | Nfya | Rat | valproic acid | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of NFYA mRNA | CTD | PMID:28001369 | Nfya | Rat | vorinostat | increases expression | ISO | NFYA (Homo sapiens) | 6480464 | vorinostat results in increased expression of NFYA mRNA | CTD | PMID:27188386 | |