Nfya (nuclear transcription factor Y subunit alpha)

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Gene: Nfya (nuclear transcription factor Y subunit alpha) Rattus norvegicus

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Symbol:

Nfya

Name:

nuclear transcription factor Y subunit alpha

RGD ID:

70976

Description:

Exhibits transcription cofactor binding activity. Predicted to contribute to transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of stem cell proliferation; positive regulation of transcription from RNA polymerase II promoter in response to iron; and regulation of stem cell population maintenance. Localizes to CCAAT-binding activity factor complex. Orthologous to human NFYA (nuclear transcription factor Y subunit alpha); PARTICIPATES IN altered p53 signaling pathway; antigen processing and presentation pathway; tuberculosis pathway; INTERACTS WITH 6-propyl-2-thiouracil; acetamide; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

CAAT box DNA-binding protein subunit A; CAAT-box DNA-binding protein subunit A; CBF-A; CBF-B; CCAAT-binding transcription factor subunit A; CCAAT-binding transcription factor subunit B; NF-YA; nuclear transcription factor Y subunit A; nuclear transcription factor-Y alpha

Orthologs:

Homo sapiens (human) : NFYA (nuclear transcription factor Y subunit alpha) HGNC Alliance
Mus musculus (house mouse) : Nfya (nuclear transcription factor-Y alpha) MGI Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfya (nuclear transcription factor Y subunit alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : NFYA (nuclear transcription factor Y subunit alpha)
Canis lupus familiaris (dog) : NFYA (nuclear transcription factor Y subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfya (nuclear transcription factor Y subunit alpha)
Sus scrofa (pig) : NFYA (nuclear transcription factor Y subunit alpha)
Chlorocebus sabaeus (African green monkey) : NFYA (nuclear transcription factor Y subunit alpha)
Heterocephalus glaber (naked mole-rat) : Nfya (nuclear transcription factor Y subunit alpha)

more info ...

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NFYA (nuclear transcription factor Y subunit alpha)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Nfya (nuclear transcription factor-Y alpha)	HGNC	Treefam, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Nfya (nuclear transcription factor Y subunit alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NFYA (nuclear transcription factor Y subunit alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NFYA (nuclear transcription factor Y subunit alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nfya (nuclear transcription factor Y subunit alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NFYA (nuclear transcription factor Y subunit alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	NFYA (nuclear transcription factor Y subunit alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nfya (nuclear transcription factor Y subunit alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	NFYA (nuclear transcription factor Y subunit alpha)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Mus musculus (house mouse):	Nfya (nuclear transcription factor-Y alpha)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	nfya (nuclear transcription factor Y, alpha)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|TreeFam)
Saccharomyces cerevisiae (baker's yeast):	HAP2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|TreeFam)
Drosophila melanogaster (fruit fly):	Nf-YA	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|TreeFam)
Caenorhabditis elegans (roundworm):	nfya-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	nfya-2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	9	14,551,752 - 14,577,002 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	14,551,758 - 14,576,967 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	13,474,255 - 13,499,504 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	7,970,040 - 7,994,375 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	9	7,970,039 - 7,994,375 (+)	NCBI
Celera	9	10,361,436 - 10,385,715 (+)	NCBI		Celera
Cytogenetic Map	9	q12	NCBI

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Genomics

Comparative Map Data

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QTLs in Region (Rnor_6.0)

miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences

Protein Sequences

Transcriptome

Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links

Nomenclature History

RGD Curation Notes

More on Nfya
	Alliance Gene
	NCBI Gene
	Ensembl Gene
	JBrowse: rn5 rn6
	NCBI Genome Data Viewer

RGD Object Information
RGD ID:	70976
Created:	2002-07-09
Species:	Rattus norvegicus
Last Modified:	2020-10-13
Status:	ACTIVE

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

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MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)