Ciaa3 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Ciaa3 (CIA Autoantibody QTL 3) Rattus norvegicus

Symbol: Ciaa3
Name: CIA Autoantibody QTL 3
RGD ID: 61450
Trait: blood autoantibody amount   (VT:0003725)    
Measurement Type: calculated serum anti-type 2 collagen antibody titer   (CMO:0001279)    
LOD Score: 6.5
P Value: Not Available
Variance: Not Available
Inheritance Type: recessive
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.297,954,720 - 22,071,169RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.095,724,254 - 25,692,342RGD_MAPPER_PIPELINERnor6.0
Rnor_5.094,772,291 - 24,554,173RGDRnor5.0
RGSC_v3.4918,347,567 - 63,347,567RGDRGSC3.4
RGSC_v3.1918,344,890 - 63,344,890RGD
Cross Type: F2
Strains Crossed: BN DA 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
C3 is a candidate Gene for Ciaa3
Vav1 is a candidate Gene for Ciaa3

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
BN  (IEA)
DA  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Genetic dissection of a rat model for rheumatoid arthritis: significant gender influences on autosomal modifier loci Furuya T, etal., Hum Mol Genet 2000 Sep 22;9(15):2241-50
2. Identification of four new quantitative trait loci regulating arthritis severity and one new quantitative trait locus regulating autoantibody production in rats with collagen-induced arthritis. Griffiths MM, etal., Arthritis Rheum 2000 Jun;43(6):1278-89
3. Quest for arthritis-causative genetic factors in the rat. Joe B Physiol Genomics. 2006 Oct 3;27(1):1-11. Epub 2006 Jun 27.
4. The complexity in hunting for candidate genes within QTL that determine susceptibility to arthritis in rats. Xiong Q, etal., Crit Rev Immunol. 2008;28(2):127-57.
5. Genetic and molecular basis of quantitative trait loci of arthritis in rat: genes and polymorphisms. Xiong Q, etal., J Immunol. 2008 Jul 15;181(2):859-64.
Related QTLs

Related QTL Description Reference
Cia15 maps to same region RGD:61066


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
3080Mep1ameprin A subunit alpha91747463417504147Rat
3549Prph2peripherin 291406614914081454Rat
2719Gnmtglycine N-methyltransferase91425467514258028Rat
69198Rcan2regulator of calcineurin 291695947817174823Rat
61899Slc29a1solute carrier family 29 member 191539966115414203Rat
61871RhagRh-associated glycoprotein92006980020097836Rat
70892Cdc5lcell division cycle 5-like91556494915603453Rat
2282Runx2RUNX family transcription factor 291616750416492826Rat
2293Ccnd3cyclin D391339416113400341Rat
3943Pgcprogastricsin91325746213265682Rat
621699Slc22a7solute carrier family 22 member 791454707314554354Rat
620382Dnph12'-deoxynucleoside 5'-phosphate N-hydrolase 191448129614484034Rat
621637Pex6peroxisomal biogenesis factor 691425814514270335Rat
620659Clic5chloride intracellular channel 591671098016813502Rat
631367Spats1spermatogenesis associated, serine-rich 191552717915562286Rat
621653Crisp2cysteine-rich secretory protein 292010764920131967Rat
619991Vegfavascular endothelial growth factor A91495530014970641Rat
621679Adgrf5adhesion G protein-coupled receptor F591751759617624107Rat
727959Byslbystin-like91338280613392557Rat
620787Slc25a27solute carrier family 25, member 2791730689817333942Rat
619846Crisp3cysteine-rich secretory protein 392043205120472663Rat
621388Ptcrapre T-cell antigen receptor alpha91421890714229141Rat
727803Cd2apCD2-associated protein91808674418182744Rat
621070Kif6kinesin family member 691107620311373205Rat
1304864Tfap2dtranscription factor AP-2 delta92168057721744840Rat
70976Nfyanuclear transcription factor Y subunit alpha91258743712613911Rat
1302946Capn11calpain 1191534405915365604Rat
735070NfkbieNFKB inhibitor epsilon91544360015450437Rat
1306415Med20mediator complex subunit 2091337014613382756Rat
1306321Tfap2btranscription factor AP-2 beta92178625121816054Rat
1306128Daam2dishevelled associated activator of morphogenesis 291142891311546982Rat
1306367Gtpbp2GTP binding protein 291481396414823419Rat
1305862Tmem63btransmembrane protein 63B91531386715340722Rat
1307308Tnfrsf21TNF receptor superfamily member 2191787915617954085Rat
1307167Trerf1transcriptional regulating factor 191363161913858326Rat
1306555Klc4kinesin light chain 491433716414351075Rat
1306696Abcc10ATP binding cassette subfamily C member 1091465724214677178Rat
1306718Adgrf2adhesion G protein-coupled receptor F291823838918248745Rat
1306756Tbcctubulin folding cofactor C91409885514100043Rat
1305744Tcte1t-complex-associated testis expressed 191546357315482258Rat
1308423Taf8TATA-box binding protein associated factor 891349189213511713Rat
1303075Hsp90ab1heat shock protein 90 alpha family class B member 191543298615438358Rat
1309583Tfebtranscription factor EB91319889013254726Rat
1359199Enpp5ectonucleotide pyrophosphatase/phosphodiesterase family member 591691018716917633Rat
1309143Dlk2delta like non-canonical Notch ligand 291467710214681584Rat
1309689Polr1cRNA polymerase I and III subunit C91473574014739852Rat
1311522Xpo5exportin 591474018214778171Rat
1310472Ptk7protein tyrosine kinase 791435215514418473Rat
1305680BicralBICRA like chromatin remodeling complex associated protein91410025314185368Rat
1308185Yipf3Yip1 domain family, member 391473028914735644Rat
1308469Rpl7l1ribosomal protein L7-like 191419810114206119Rat
1308471Mocs1molybdenum cofactor synthesis 191154753311573935Rat
1310617Aars2alanyl-tRNA synthetase 2, mitochondrial91548463915496116Rat
1311516Mrps10mitochondrial ribosomal protein S1091361489713624819Rat
1308727Apobec2apolipoprotein B mRNA editing enzyme catalytic subunit 291256495512578461Rat
1308712Guca1aguanylate cyclase activator 1A91358898813598566Rat
1308299Oard1O-acyl-ADP-ribose deacylase 191257689412587264Rat
727869Opn5opsin 591836839318416098Rat
1306240Mrpl14mitochondrial ribosomal protein L1491530284015315195Rat
1308689Enpp4ectonucleotide pyrophosphatase/phosphodiesterase 491688892316898860Rat
1305956Tdrd6tudor domain containing 691734403317359348Rat
1306666Ppp2r5dprotein phosphatase 2, regulatory subunit B', delta91427036414300396Rat
1308191Guca1bguanylate cyclase activator 1B91359961913607455Rat
1309175Mad2l1bpMAD2L1 binding protein91483213314836458Rat
1308708Tjap1tight junction associated protein 191470141814725623Rat
1307147Mrpl2mitochondrial ribosomal protein L291433323314337006Rat
1307182B430306N03RiklRIKEN cDNA B430306N03 gene91268129012690555Rat
735229Mrps18amitochondrial ribosomal protein S18A91485332214869819Rat
1307105Klhdc3kelch domain containing 391430234514308736Rat
1310226Frs3fibroblast growth factor receptor substrate 391328855913297285Rat
1309841Trem2triggering receptor expressed on myeloid cells 291264760512654190Rat
1306627Pgk2phosphoglycerate kinase 292048036720481933Rat
1310285Adgrf1adhesion G protein-coupled receptor F191766125817696359Rat
1311386Foxp4forkhead box P491305850613115406Rat
1305477Trem3triggering receptor expressed on myeloid cells 391274982112762547Rat
1309467Trem1triggering receptor expressed on myeloid cells 191276381912779285Rat
1311406Ncr2natural cytotoxicity triggering receptor 291277719512828437Rat
1309893PolhDNA polymerase eta91477835514813210Rat
1310693Rsph9radial spoke head component 991484011514852950Rat
1307471Cyp39a1cytochrome P450, family 39, subfamily a, polypeptide 191723045517306775Rat
1563979Prickle4prickle planar cell polarity protein 491329749413305635Rat
1561390Lrrc73leucine rich repeat containing 7391472615714730144Rat
1562008Cul9cullin 991443594814479552Rat
1559758Defb18defensin beta 1892085223020853247Rat
1560245Defb49defensin beta 4992083268620837352Rat
1563347Rftn1raftlin lipid raft linker 191080461111002084Rat
1565216Adgrf4adhesion G protein-coupled receptor F491827205018303219Rat
1359641Adgre4adhesion G protein-coupled receptor E4997581069901908Rat
1565718Defb17defensin beta 1792088024620883875Rat
1562074Tmem151btransmembrane protein 151B91545644615464289Rat
1559518Ttbk1tau tubulin kinase 191449316614538372Rat
1559663St6gal2ST6 beta-galactoside alpha-2,6-sialyltransferase 2991817449274161Rat
1560271MdfiMyoD family inhibitor91315680613175218Rat
1310513Usp49ubiquitin specific peptidase 4991330564013366132Rat
1563020Ptchd4patched domain containing 491846293418666272Rat
1559787Srfserum response factor91442645314435734Rat
1310734Pla2g7phospholipase A2 group VII91736221417404476Rat
1564244Cyp2ac1cytochrome P450, family 2, subfamily ac, polypeptide 192003582320058570Rat
1560151Ankrd66ankyrin repeat domain 6691742143217441212Rat
1311831Lrfn2leucine rich repeat and fibronectin type III domain containing 291189742512066177Rat
1359451Cenpqcentromere protein Q91995712219972807Rat
15858341700067P10RiklRIKEN cDNA 1700067P10 gene like91289529412896592Rat
1585869Ncr2l1natural cytotoxicity triggering receptor 2 like 191284354212858881Rat
1583567Tomm6translocase of outer mitochondrial membrane 691330426913305637Rat
1586485Uqcrb-ps2ubiquinol-cytochrome c reductase binding protein, pseudogene 292035341420353798Rat
1587643Glyatl3glycine-N-acyltransferase-like 391997749319995723Rat
1582873Pot1bprotection of telomeres 1B996703559728624Rat
1582883Vom2r77vomeronasal 2 receptor, 77995728749638896Rat
1587368Unc5clunc-5 family C-terminal like91252810912543382Rat
1583221Zfp318zinc finger protein 31891456295814601557Rat
1583959LOC691414hypothetical protein LOC691414999547209964136Rat
1561662C9h6orf132similar to human chromosome 6 open reading frame 13291352482213561756Rat
1565018Crip3cysteine-rich protein 391455445014557344Rat
1562466Defb16-psdefensin beta 16 pseudogene92087506420883875Rat
1565959RGD1565959RGD156595991287369712886364Rat
1565175Treml1triggering receptor expressed on myeloid cells-like 191263558412642324Rat
1565318Slc35b2solute carrier family 35 member B291543859415442227Rat
1590246Polr1hasRNA polymerase I subunit H, antisense91609862416099790Rat
1591345Girdinl1girders of actin filaments like 191066477010683943Rat
1588569Vom2r76vomeronasal 2 receptor, 76994679619492317Rat
1590872Vom2r-ps138vomeronasal 2 receptor, pseudogene 138999264929946415Rat
1590757Crisp1cysteine-rich secretory protein 192074177520768796Rat
1588829C9h6orf141similar to human chromosome 6 open reading frame 14192002491620029094Rat
1589660Taldo1-ps1transaldolase 1, pseudogene 1982753008276318Rat
1588537Spetex-2Fl1Spetex-2F protein like 191007694910085216Rat
1587048Cul7cullin 791431910214333035Rat
1587662Mmutmethylmalonyl-CoA mutase91992872019956985Rat
1584839Kcnk16-ps1potassium two pore domain channel subfamily K member 16, pseudogene 191105906911064995Rat
1587021Treml4triggering receptor expressed on myeloid cells-like 491271896812743879Rat
1585305Prmt1-ps3protein arginine methyltransferase 1, pseudogene 392129985121301148Rat
1587039Treml2triggering receptor expressed on myeloid cells-like 291269445312705379Rat
1596995Yju2-ps1YJU2 splicing factor, pseudogene 191583190715835273Rat
1591714Dazldeleted in azoospermia-like91069559310712330Rat
1594018Tspo2translocator protein 291254461512548563Rat
1593237Ubr2ubiquitin protein ligase E3 component n-recognin 291398242714062315Rat
1591316Supt3hSPT3 homolog, SAGA and STAGA complex component91587829616206768Rat
1597751Mea1male-enhanced antigen 191430028314304130Rat
1596723C9h6orf226smilar to human chromosome 6 open reading frame 22691420798814209134Rat
1597709Cnpy3canopy FGF signaling regulator 391423347814247847Rat
2306314Rps2-ps6ribosomal protein S2, pseudogene 691482672914827651Rat
2322325Fbxw2-ps1F-box and WD repeat domain containing 2, pseudogene 1983847868389434Rat
2321693Rrp36ribosomal RNA processing 3691430895614316959Rat
2322726Kin-ps1Kin17 DNA and RNA binding protein, pseudogene 191183393011835584Rat
6494554Rpl5-ps2ribosomal protein L5, pseudogene 291166787811669951Rat
64928821700122O11RiklRIKEN cDNA 1700122O11 gene like91293744412943012Rat
6485345Cimip3ciliary microtubule inner protein 391356066913582987Rat
6496783Fbxw2-ps3F-box and WD repeat domain containing 2, pseudogene 3984033958408043Rat
7526556LOC102550162uncharacterized LOC10255016291510214115135118Rat
7650881LOC102547352uncharacterized LOC10254735291188214611883458Rat
7642378N4bp1-ps2Nedd4 binding protein 1, pseudogene 2997173159720322Rat
7629065LOC102548435uncharacterized LOC10254843591266494012672794Rat
7570521LOC102548200uncharacterized LOC10254820091244695312450780Rat
7594246LOC102554116uncharacterized LOC10255411691303256913038429Rat
7556959Sik3-ps1SIK family kinase 3, pseudogene 1995068299510000Rat
7587989LOC102555783uncharacterized LOC10255578391687721816888739Rat
7706024LOC102547840uncharacterized LOC10254784091241534912423539Rat
7683517LOC102547709uncharacterized LOC10254770991225737912272305Rat
7671069LOC102550363uncharacterized LOC10255036391523935115259876Rat
7710987LOC102554309uncharacterized LOC10255430991326177413266883Rat
9095701LOC103690501uncharacterized LOC10369050191527904415280845Rat
9112006Rpl27al9ribosomal protein L27A like 9985164298517495Rat
9222779LOC103690504ubiquitin-conjugating enzyme E2 N-like92135783621358387Rat
9281506Spetex2gl1Spetex-2G protein like 19997335310002936Rat
9295718LOC103690509activated RNA polymerase II transcriptional coactivator p15 pseudogene91480024014802871Rat
9450374LOC103690514exocrine gland-secreted peptide 1-like92014367220150293Rat
11433453LOC108351994exocrine gland-secreted peptide 1-like92020572720212941Rat
11470506LOC108351893uncharacterized LOC10835189391559848615607891Rat
11438663LOC10835187660S ribosomal protein L7 pseudogene997649519765788Rat
11432264LOC108351894uncharacterized LOC10835189491668964916700163Rat
11426996Mymxmyomixer, myoblast fusion factor91539708615398263Rat
11396250Spetex2el3Spetex-2E protein like 391002522110036771Rat
11397802LOC108351900uncharacterized LOC10835190092066334820670645Rat
11376343LOC108351892uncharacterized LOC10835189291548649215493269Rat
11390506Rpl36a-ps6ribosomal protein L36A, pseudogene 692018293820195730Rat
11477544LOC108351895uncharacterized LOC10835189591681879716827112Rat
11484729LOC108351887uncharacterized LOC10835188791165233911678809Rat
41113996LOC120094785uncharacterized LOC12009478591460058414622471Rat
41251599LOC120094867U6 spliceosomal RNA91469494714695052Rat
41279270Fbxw2-ps4F-box and WD repeat domain containing 2, pseudogene 4983940838398728Rat
41285703LOC120094630uncharacterized LOC12009463091157517911591773Rat
41116177LOC120094792uncharacterized LOC12009479291574755815751915Rat
41116623LOC120094640uncharacterized LOC12009464091743427317459213Rat
41148077LOC120094642uncharacterized LOC12009464291988249019909177Rat
41389612LOC120094832ERC protein 2-like91005061210051922Rat
41188929LOC120094859U6 spliceosomal RNA91389540213895505Rat
41343382Atp5mg-ps1ATP synthase membrane subunit g, pseudogene 191776067617760986Rat
41179785LOC120094634uncharacterized LOC12009463491341234313489689Rat
41216390LOC120094920small nucleolar RNA SNORA1792152044521520572Rat
41291055LOC120094873U6 spliceosomal RNA91380992913810029Rat
41372167LOC120094984U6 spliceosomal RNA91405162814051732Rat
41127923LOC120094887small nucleolar RNA SNORA36 family91572372115723851Rat
41218959LOC120094631uncharacterized LOC12009463191181960811833871Rat
41372763LOC12009478940S ribosomal protein S29-like91520739015209191Rat
41349498LOC120094635uncharacterized LOC12009463591582535615830665Rat
41106882LOC120094874U7 small nuclear RNA92131650421316566Rat
41272310LOC120094841uncharacterized LOC12009484191779406017801338Rat
41131560Ubbl3ubiquitin B like 392066143520662315Rat
41295786LOC120094632uncharacterized LOC12009463291241647712417396Rat
41403460LOC120094638uncharacterized LOC12009463891672272016737939Rat
41012750LOC120094636uncharacterized LOC12009463691657019416589380Rat
40926438LOC120094981U6 spliceosomal RNA91358758613587697Rat
40979134LOC120094879U7 small nuclear RNA92131665421316712Rat
40999450LOC120094644uncharacterized LOC12009464492046236620468036Rat
40929597Trnat-agu32transfer RNA threonine (anticodon AGU) 3291839905618399136Rat
41005958LOC120094637uncharacterized LOC12009463791674266316765020Rat
40935681LOC120094870U6 spliceosomal RNA996740979674202Rat
40988429LOC120094938U1 spliceosomal RNA91170829711708457Rat
40995448LOC120094788uncharacterized LOC12009478891518871815190122Rat
41050827LOC120094784uncharacterized LOC12009478491442431014426287Rat
41053828LOC120094840uncharacterized LOC12009484091774401517747544Rat
41143660Hnrnpd-ps2heterogeneous nuclear ribonucleoprotein D, pseudogene 2987123408713866Rat
41220628LOC120094639uncharacterized LOC12009463991725419617257745Rat
41297475LOC120094927U1 spliceosomal RNA92058290620583063Rat
41031628LOC120094909small nucleolar RNA SNORA1791238394412384075Rat
41032701LOC120094842uncharacterized LOC12009484292054784420555930Rat
41065341LOC120093043small nucleolar RNA SNORA1991420347414203604Rat
41041357Rcn1-ps7reticulocalbin 1, pseudogene 791006702710067832Rat
41069681LOC120094793uncharacterized LOC12009479391624432516245932Rat
41022215LOC120094839uncharacterized LOC12009483991285926412864171Rat
41309930LOC120094646uncharacterized LOC12009464692070335220714779Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10252D7Mit1213691077552010775580Ratregion
10873D9Uwm310191455455514554654Ratregion
36063D9Rat3717191588777915887950Ratregion
36151D9Rat4616991076977510769932Ratregion
36157D9Rat3116292121837921218540Ratregion
37472D9Rat8724291868264518682873Ratregion
35336D9Rat3928891563800415638292Ratregion
35437D9Rat3815191590616415906328Ratregion
35439D9Rat3514591722047617220609Ratregion
37634D9Rat7921591420956414209783Ratregion
37692D9Rat8221691131173811311958Ratregion
37776D9Rat8820991112370211123900Ratregion
36510D9Rat409291401384014013932Ratregion
36707D9Rat3216091975163419751792Ratregion
34963D9Rat3415391836330118363454Ratregion
35104D9Rat16013291518425015184382Ratregion
35623D9Rat4113391353377013533896Ratregion
35871D9Rat3614791696139816961545Ratregion
39890D9Rat19322191711170917111930Ratregion
38320D9Rat6619991704407517044281Ratregion
38684D9Rat7823391700715217007395Ratregion
38764D9Rat8111291487536514875477Ratregion
40170D9Rat13513591176556411765695Ratregion
41928D9Rat3328691867069618670972Ratregion
42879D9Rat18120691751034817510538Ratregion
42880D9Rat18220091718628417186488Ratregion
41218D9Rat13413091345703913457174Ratregion
41490D9Rat138167985680328568177Ratregion
40894D9Rat13324991463350614633755Ratregion
41556D9Rat13216091549913615499288Ratregion
43124D18Rat12224291957244019572673Ratregion
44547D9Got2615691758455117584707Ratregion
44549D9Got1511591173586111735976Ratregion
44550D9Got1226491102999111030254Ratregion
44551D9Got1440191184997111850371Ratregion
44553D9Got1615191338053513380686Ratregion
44555D9Got14024391364766013647903Ratregion
44555D9Got14024391364766013648039Ratregion
44556D9Got1818191505138115051562Ratregion
44557D9Got1717491538092615381100Ratregion
44558D9Hmgc122891647065216470878Ratregion
44559D9Got2212991666525216665381Ratregion
44560D9Got2324691756517617565422Ratregion
44561D9Got2521491784387917844093Ratregion
44562D9Got2016491730445817304622Ratregion
44563D9Got2117891766435817664536Ratregion
44564D9Got2717691875150418751680Ratregion
44565D9Got2816392191746021917623Ratregion
44567D9Wox1915692207116922071345Ratregion
60652D9Got1316491124880511248969Ratregion
60658D9Got1924791709245217092701Ratregion
60660D9Got2421591711998617120201Ratregion
60825D9Wox20107987630218763131Ratregion
60827D9Wox23160979545567954720Ratregion
62475D1Uia414091743533817435380Ratregion
62508D9Uia1187992644979264638Ratregion
1630338D9Got20225791390887313909130Ratregion
1631969D9Wox2816791340125813401435Ratregion
1629214D9Wox3624091752125117521491Ratregion
1629708D9Wox4316291497004214970204Ratregion
1638936D9Wox3814092045455120454691Ratregion
1635603D9Got21526291678928116789545Ratregion
1636087D9Wox4491340079313400943Ratregion
1636259D9Cebr191087323910873477Ratregion
1637006D9Got245229982103738210602Ratregion
1638026D9Wox4219091496905414969244Ratregion
1634267D9Got231267987777998778067Ratregion
1634453D9Got21319991680848016808679Ratregion
7206718D17Mit3521691546358315463799Ratregion
5038924RH12741121791473936414739673Ratregion
5036410UniSTS:14385023191430034914300580Ratregion
5039092RH12750821091443541814435628Ratregion
5039152RH12754219691543871715438913Ratregion
5036631AU04865320392166439821664601Ratregion
5037011AU04991518791372180413721991Ratregion
5035713Runx230991616772616168035Ratregion
5031352PMC150810P110391637176516371868Ratregion
5028593AI4152818791472531814725405Ratregion
5028637RH125689201987138678714067Ratregion
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5026628RH13293519891258627212586470Ratregion
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5026742RH13336218391424755314247747Ratregion
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5035490BQ19602621092020793720208147Ratregion
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5027671Dscr1l123091696177316962003Ratregion
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5025204RH12741621491330514913305532Ratregion
5025206RH12742421191587871515878926Ratregion
5027819RH9486719091261161312611803Ratregion
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5031029BE12123316791310130613101473Ratregion
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5046654RH13187820191544287715443078Ratregion
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5042054RH12921220892006983520070043Ratregion
5042204RH12929921091330538513305595Ratregion
5039670RH12783921191430031914300530Ratregion
5040254RH12817820791530301715303224Ratregion
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5040454RH12829220691257702912577235Ratregion
5072776RH13704620891541389315414101Ratregion
5071972RH13539121691359831013598527Ratregion
5075446RH13859813091359442813594558Ratregion
5075654RH13871914491459815614598300Ratregion
5072278RH13675621991406617014066387Ratregion
5076364RH13913212491293788712938011Ratregion
5072586RH13693418291750967617509858Ratregion
5072684RH13699221791534045515340672Ratregion
5076626RH13928513291359967613599808Ratregion
5075388RH13856519491470794914708143Ratregion
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5079538RH14105618191430850614308687Ratregion
5078316RH14027020691339222613392432Ratregion
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5078580RH14042621891452513714525355Ratregion
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5073414RH13742218691100293511003122Ratregion
5071960RH13538418191351868113518862Ratregion
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5072170RH13669312391258828612588409Ratregion
5071732RH13525318191443762614437807Ratregion
5071774RH13527620091422880314229003Ratregion
5063376BI30178720991236329412363504Ratregion
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5067232AU04788118391411483814115021Ratregion
5067308AU04783413691548934215489478Ratregion
5067488AU04771410692141073121410837Ratregion
5067640AU04762312091092899210929112Ratregion
5067764AU04755024591514459115144831Ratregion
5068402AU04716818791883681418837001Ratregion
5068548AU04708019491304802313048217Ratregion
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5070404AI84681614291530326115303403Ratregion
5069246AU04662328991122706611227350Ratregion
5063502BF39896711591716404117164156Ratregion
5062256BE10640415192048170020481851Ratregion
5063810AW53527718091792447317924653Ratregion
5063946AW53581315491456886214569016Ratregion
5062684BF40384321291181977811820231Ratregion
5060096BF38848716791365030613650473Ratregion
5060126BF38852617891415288214153060Ratregion
5062148BE10626318091337305613373236Ratregion
5063602BE10782015091339057113390730Ratregion
5060528BE11029315491735917517359329Ratregion
5062564BF40342017891687734916877527Ratregion
5061128AW52616516091420489514205055Ratregion
5062870BE11313016091447060614470766Ratregion
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5061512BE10537315591596980615969961Ratregion
5087368BQ20949021391656971516569928Ratregion
5086598AA89179620991330538113305590Ratregion
5082751BF39002024591347642313476668Ratregion
5083205BF39098920691401951614019722Ratregion
5083255BI27583710491325808013258839Ratregion
5088247AU04845419291288859512888787Ratregion
5089297AU04907220791092887610929083Ratregion
5083535BI27609117591682687616827051Ratregion
5088761AU04876117091838425418384424Ratregion
5088869AU04881814691542941415429560Ratregion
5089659AU04928625591131173811311993Ratregion
5085014AI01010714992038721720387366Ratregion
5087805D5Wsu145e276987149268715204Ratregion
5085451BM39039516091169231311692473Ratregion
5085483AI17714720691413032114130527Ratregion
5080942RH14187220291457189814572100Ratregion
5090429AU049745282982536598253941Ratregion
5081306RH14208419691472627914726475Ratregion
5085663BI27677916391367391213674075Ratregion
5086016BM38383015991431594814316098Ratregion
5081006RH14190915891352484713525005Ratregion
5082963BI28143911192047193220472043Ratregion
5083511BE10032921191361489613615107Ratregion
5085788BM38501716191695265816952819Ratregion
5503260UniSTS:2376588391418475414184837Ratregion
5503470SRF_346773091443353014434260Ratregion
5507819REN5932125391291399012914243Ratregion
5504111px-6g713791930989719310034Ratregion
5504570PMC305791P167191442718914427903Ratregion
5504570PMC305791P167191442723214427903Ratregion
5505506D4S33301671990139299015512Ratregion
5504438PMC20712P193491495436714955301Ratregion
5506698REN3602081491148830111489115Ratregion
5500424REN6052925091320278613203036Ratregion
5499697Dazl110691070094810702054Ratregion
5502303RH12435427391339416613394439Ratregion
5500414REN5958323691297041612970652Ratregion
5500416REN5959524091297311212973352Ratregion
5500418REN5982725291303250213032754Ratregion
5500420REN5999425491307481213075066Ratregion
5500422REN6051524791319949513199742Ratregion
5503436stSG63486098491310355213104536Ratregion
5500897D4S157952291096758210968104Ratregion
5501742MARC_10377-10378:999102157:1147591477488414776359Ratregion
5506575VEGF_112782491496919014970014Ratregion
5501886MARC_16785-16786:1033500245:365091433079814331448Ratregion
5502447RH1248918791431930814319395Ratregion
5502975Tcfap2b47992181144221811921Ratregion
Position Markers

Flank 1: (D9Wox19)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2922,071,169 - 22,071,345 (+)MAPPER
Rnor_6.0925,692,342 - 25,692,517NCBI
Rnor_5.0924,554,173 - 24,554,348UniSTS
RGSC_v3.4918,347,568 - 18,347,743UniSTS
RGSC_v3.4918,347,567 - 18,347,743RGD
RGSC_v3.1918,344,890 - 18,345,065RGD
Celera919,655,621 - 19,655,796UniSTS
RH 3.4 Map9194.1UniSTS
RH 3.4 Map9194.1RGD
RH 2.0 Map9162.0RGD
Cytogenetic Map9 RGD
Peak: (D9Wox23)
Rat AssemblyChrPosition (strand)Source
mRatBN7.297,954,556 - 7,954,720 (+)MAPPER
Rnor_6.095,724,091 - 5,724,254NCBI
Rnor_5.094,772,128 - 4,772,291UniSTS
Celera93,787,179 - 3,787,342UniSTS
Cytogenetic Map9 RGD
Flank 2: (D9Wox23)
Rat AssemblyChrPosition (strand)Source
mRatBN7.297,954,556 - 7,954,720 (+)MAPPER
Rnor_6.095,724,091 - 5,724,254NCBI
Rnor_5.094,772,128 - 4,772,291UniSTS
Celera93,787,179 - 3,787,342UniSTS
Cytogenetic Map9 RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9114209783Rat
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
1578675Bss17Bone structure and strength QTL 173.8femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)9336865213533896Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
724543Cm20Cardiac mass QTL 203.9heart mass (VT:0007028)calculated heart weight (CMO:0000073)91696139840594091Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Ciaa3

RGD Curation Notes
Note Type Note Reference
qtl_gene whole genome analysis using PGMapper revealed Vegfa as RA associated gene 2300074
qtl_gene 150 known and 39 novel genes were found in an analysis based on PubMed and OMIM data 2307198
qtl_general does not associate with CIA severity 61066
qtl_statistics_details 99% confidence interval was 9.4 cM 61066
qtl_statistics_details for porcine type II collagen LOD = 6.5, for rat type II collagen LOD = 5.2 61066