Tfap2b (transcription factor AP-2 beta) - Rat Genome Database

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Gene: Tfap2b (transcription factor AP-2 beta) Rattus norvegicus
Analyze
Symbol: Tfap2b
Name: transcription factor AP-2 beta
RGD ID: 1306321
Description: Enables chromatin binding activity. Involved in response to lithium ion and response to xenobiotic stimulus. Located in nucleus. Human ortholog(s) of this gene implicated in Char syndrome and patent ductus arteriosus. Orthologous to human TFAP2B (transcription factor AP-2 beta); INTERACTS WITH 1,2-dimethylhydrazine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC301285; Tcfap2b; transcription factor AP-2-beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2921,786,250 - 21,815,785 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl921,786,258 - 21,814,520 (+)Ensembl
Rnor_6.0925,410,669 - 25,440,568 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl925,410,669 - 25,440,411 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0924,271,604 - 24,302,855 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4918,052,402 - 18,082,202 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1918,049,775 - 18,079,184 (+)NCBI
Celera919,374,332 - 19,403,772 (+)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anatomical structure development  (IBA)
aorta morphogenesis  (ISO,ISS)
calcium ion homeostasis  (ISO,ISS)
cellular ammonium homeostasis  (ISO,ISS)
cellular creatinine homeostasis  (ISO,ISS)
cellular urea homeostasis  (ISO,ISS)
collecting duct development  (ISO,ISS)
distal tubule development  (ISO,ISS)
ductus arteriosus closure  (ISO,ISS)
fat cell differentiation  (ISO)
forelimb morphogenesis  (ISO,ISS)
gene expression  (ISO)
glucose homeostasis  (ISO,ISS)
glucose metabolic process  (ISO,ISS)
hindlimb morphogenesis  (ISO,ISS)
kidney development  (ISO,ISS)
magnesium ion homeostasis  (ISO,ISS)
metanephric nephron development  (ISO)
negative regulation of apoptotic process  (ISO,ISS)
negative regulation of cell population proliferation  (ISO,ISS)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO,ISS)
negative regulation of transcription, DNA-templated  (ISO,ISS)
neuron apoptotic process  (IEA,ISO)
phosphate ion homeostasis  (ISO,ISS)
positive regulation of cell population proliferation  (ISO,ISS)
positive regulation of neuron apoptotic process  (ISO,ISS)
positive regulation of transcription by RNA polymerase II  (ISO,ISS)
positive regulation of transcription, DNA-templated  (ISO)
positive regulation of urine volume  (ISO,ISS)
potassium ion homeostasis  (ISO,ISS)
regulation of BMP signaling pathway  (ISO,ISS)
regulation of cell differentiation  (ISO,ISS)
regulation of cell population proliferation  (IBA)
regulation of insulin secretion  (ISO,ISS)
regulation of transcription by RNA polymerase II  (IBA,ISO,ISS)
renal water homeostasis  (ISO,ISS)
response to lithium ion  (IEP)
response to xenobiotic stimulus  (IEP)
retina layer formation  (ISO)
sensory organ development  (ISO)
skin development  (ISO)
smooth muscle tissue development  (ISO)
sodium ion homeostasis  (ISO,ISS)
sympathetic nervous system development  (ISO,ISS)
transcription by RNA polymerase II  (IEA,ISO)

Cellular Component
nucleus  (IBA,IDA,ISO,ISS)

References

Additional References at PubMed
PMID:7555706   PMID:7559606   PMID:9271117   PMID:11505339   PMID:11694877   PMID:12072434   PMID:12169688   PMID:12695560   PMID:15940393   PMID:16373396   PMID:17525748   PMID:19325541  
PMID:20448150   PMID:20607706   PMID:21539825   PMID:21829553  


Genomics

Comparative Map Data
Tfap2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2921,786,250 - 21,815,785 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl921,786,258 - 21,814,520 (+)Ensembl
Rnor_6.0925,410,669 - 25,440,568 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl925,410,669 - 25,440,411 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0924,271,604 - 24,302,855 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4918,052,402 - 18,082,202 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1918,049,775 - 18,079,184 (+)NCBI
Celera919,374,332 - 19,403,772 (+)NCBICelera
Cytogenetic Map9q13NCBI
TFAP2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38650,818,355 - 50,847,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl650,818,723 - 50,847,619 (+)EnsemblGRCh38hg38GRCh38
GRCh37650,786,584 - 50,815,332 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36650,894,398 - 50,923,285 (+)NCBINCBI36hg18NCBI36
Build 34650,894,541 - 50,919,634NCBI
Celera652,342,514 - 52,371,233 (+)NCBI
Cytogenetic Map6p12.3NCBI
HuRef650,517,924 - 50,546,498 (+)NCBIHuRef
CHM1_1650,789,288 - 50,818,174 (+)NCBICHM1_1
Tfap2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39119,279,132 - 19,309,069 (+)NCBIGRCm39mm39
GRCm39 Ensembl119,279,138 - 19,308,800 (+)Ensembl
GRCm38119,208,908 - 19,238,845 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl119,208,914 - 19,238,576 (+)EnsemblGRCm38mm10GRCm38
MGSCv37119,198,995 - 19,228,815 (+)NCBIGRCm37mm9NCBIm37
MGSCv36119,194,128 - 19,223,948 (+)NCBImm8
Celera119,103,515 - 19,133,268 (+)NCBICelera
Cytogenetic Map1A3NCBI
Tfap2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554117,142,607 - 7,170,467 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554117,143,095 - 7,171,285 (-)NCBIChiLan1.0ChiLan1.0
TFAP2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1651,635,899 - 51,664,691 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl651,635,899 - 51,664,691 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0650,376,157 - 50,406,740 (+)NCBIMhudiblu_PPA_v0panPan3
TFAP2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11218,544,176 - 18,574,300 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1218,544,446 - 18,572,902 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1218,436,730 - 18,462,495 (+)NCBI
ROS_Cfam_1.01219,041,005 - 19,071,021 (+)NCBI
ROS_Cfam_1.0 Ensembl1219,041,155 - 19,069,637 (+)Ensembl
UMICH_Zoey_3.11218,549,889 - 18,575,642 (+)NCBI
UNSW_CanFamBas_1.01218,654,100 - 18,679,842 (+)NCBI
UU_Cfam_GSD_1.01218,791,560 - 18,817,345 (+)NCBI
Tfap2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494654,075,431 - 54,104,213 (+)NCBI
SpeTri2.0NW_0049364769,855,992 - 9,884,788 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TFAP2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl744,745,422 - 44,770,609 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1744,745,653 - 44,774,563 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2751,206,179 - 51,235,198 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TFAP2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11721,599,570 - 21,629,757 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1721,604,067 - 21,628,489 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604450,760,129 - 50,788,887 (+)NCBIVero_WHO_p1.0
Tfap2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248555,353,347 - 5,381,454 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
Tcfap2b  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2921,811,442 - 21,811,921 (+)MAPPERmRatBN7.2
Rnor_6.0925,436,224 - 25,436,702NCBIRnor6.0
Rnor_5.0924,298,653 - 24,299,131UniSTSRnor5.0
RGSC_v3.4918,078,000 - 18,078,478UniSTSRGSC3.4
Celera919,399,570 - 19,400,048UniSTS
Cytogenetic Map9q13UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
724543Cm20Cardiac mass QTL 203.9heart mass (VT:0007028)calculated heart weight (CMO:0000073)91696139840594091Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:739
Count of miRNA genes:290
Interacting mature miRNAs:370
Transcripts:ENSRNOT00000030912
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 37 25 4
Low 12 4 37 10 12
Below cutoff 1 19 15 11 13 11 3 3 22 10 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000030912   ⟹   ENSRNOP00000030726
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl921,789,325 - 21,811,605 (+)Ensembl
Rnor_6.0 Ensembl925,410,669 - 25,440,384 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000090920   ⟹   ENSRNOP00000075514
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl921,786,258 - 21,814,520 (+)Ensembl
Rnor_6.0 Ensembl925,410,717 - 25,440,411 (+)Ensembl
RefSeq Acc Id: NM_001106896   ⟹   NP_001100366
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2921,786,258 - 21,815,645 (+)NCBI
Rnor_6.0925,410,669 - 25,440,426 (+)NCBI
Rnor_5.0924,271,604 - 24,302,855 (+)NCBI
RGSC_v3.4918,052,402 - 18,082,202 (+)RGD
Celera919,374,332 - 19,403,772 (+)RGD
Sequence:
RefSeq Acc Id: XM_008766927   ⟹   XP_008765149
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2921,786,251 - 21,815,785 (+)NCBI
Rnor_6.0925,410,691 - 25,440,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039083192   ⟹   XP_038939120
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2921,786,250 - 21,815,785 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001100366 (Get FASTA)   NCBI Sequence Viewer  
  XP_008765149 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939120 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM18662 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001100366   ⟸   NM_001106896
- UniProtKB: D4A505 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765149   ⟸   XM_008766927
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000075514   ⟸   ENSRNOT00000090920
RefSeq Acc Id: ENSRNOP00000030726   ⟸   ENSRNOT00000030912
RefSeq Acc Id: XP_038939120   ⟸   XM_039083192
- Peptide Label: isoform X2
Protein Domains
TF_AP-2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2KAT2-F1-model_v2 AlphaFold A0A0G2KAT2 1-459 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696575
Promoter ID:EPDNEW_R7096
Type:initiation region
Name:Tfap2b_1
Description:transcription factor AP-2 beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0925,410,755 - 25,410,815EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306321 AgrOrtholog
BioCyc Gene G2FUF-28045 BioCyc
Ensembl Genes ENSRNOG00000011823 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000030726 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000075514 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030912 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000090920 ENTREZGENE, UniProtKB/TrEMBL
InterPro TF_AP2 UniProtKB/TrEMBL
  TF_AP2_beta UniProtKB/TrEMBL
  TF_AP2_C UniProtKB/TrEMBL
KEGG Report rno:301285 UniProtKB/TrEMBL
NCBI Gene 301285 ENTREZGENE
PANTHER PTHR10812:SF14 UniProtKB/TrEMBL
  TF_AP2 UniProtKB/TrEMBL
Pfam TF_AP-2 UniProtKB/TrEMBL
PhenoGen Tfap2b PhenoGen
PRINTS AP2BTNSCPFCT UniProtKB/TrEMBL
  AP2TNSCPFCT UniProtKB/TrEMBL
UniProt A0A0G2KAT2_RAT UniProtKB/TrEMBL
  D4A505 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-06-09 Tfap2b  transcription factor AP-2 beta  Tcfap2b  transcription factor AP-2 beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Tcfap2b  transcription factor AP-2 beta   Tcfap2b_predicted  transcription factor AP-2 beta (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Tcfap2b_predicted  transcription factor AP-2 beta (predicted)      Symbol and Name status set to approved 70820 APPROVED