Tfap2b (transcription factor AP-2 beta) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Tfap2b (transcription factor AP-2 beta) Mus musculus
Analyze
Symbol: Tfap2b
Name: transcription factor AP-2 beta
RGD ID: 1314876
MGI Page MGI
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including artery morphogenesis; kidney development; and limb morphogenesis. Acts upstream of with a negative effect on negative regulation of apoptotic process. Acts upstream of or within several processes, including negative regulation of neuron apoptotic process; positive regulation of transcription by RNA polymerase II; and sympathetic nervous system development. Located in nucleus. Is expressed in several structures, including genitourinary system; jaw; nervous system; sensory organ; and skin. Used to study Char syndrome; angle-closure glaucoma; and patent ductus arteriosus. Human ortholog(s) of this gene implicated in Char syndrome and patent ductus arteriosus. Orthologous to human TFAP2B (transcription factor AP-2 beta).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: activating enhancer-binding protein 2 beta; activating enhancer-binding protein 2-beta; AI606113; AP-2(be; AP-2(beta); AP2-beta; E130018K07Rik; Tcfap; Tcfap2b; transcription factor AP-2-beta
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39119,279,132 - 19,309,071 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl119,279,138 - 19,308,800 (+)EnsemblGRCm39 Ensembl
GRCm38119,208,908 - 19,238,845 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl119,208,914 - 19,238,576 (+)EnsemblGRCm38mm10GRCm38
MGSCv37119,198,995 - 19,228,815 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36119,194,128 - 19,223,948 (+)NCBIMGSCv36mm8
Celera119,103,515 - 19,133,268 (+)NCBICelera
Cytogenetic Map1A3NCBI
cM Map16.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA,IDA,ISO,ISS)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal ciliary body morphology  (IAGP)
abnormal circadian sleep/wake cycle  (IAGP)
abnormal cornea epithelium morphology  (IAGP)
abnormal cornea morphology  (IAGP)
abnormal cornea stroma morphology  (IAGP)
abnormal eye anterior chamber morphology  (IAGP)
abnormal eye morphology  (IAGP)
abnormal fetal ductus arteriosus morphology  (IAGP)
abnormal ion homeostasis  (IAGP)
abnormal iridocorneal angle  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal kidney physiology  (IAGP)
abnormal lens epithelium morphology  (IAGP)
abnormal non-rapid eye movement sleep pattern  (IAGP)
abnormal optic disk morphology  (IAGP)
abnormal pulmonary alveolar system morphology  (IAGP)
abnormal vascular smooth muscle physiology  (IAGP)
absent cornea endothelium  (IAGP)
anterior iris synechia  (IAGP)
anterior subcapsular cataract  (IAGP)
congestive heart failure  (IAGP)
cornea vascularization  (IAGP)
decreased amacrine cell number  (IAGP)
decreased circulating calcium level  (IAGP)
decreased cornea epithelium thickness  (IAGP)
decreased total retina thickness  (IAGP)
decreased urine calcium level  (IAGP)
decreased urine osmolality  (IAGP)
dilated proximal convoluted tubule  (IAGP)
dilated renal tubule  (IAGP)
eye opacity  (IAGP)
fused cornea and lens  (IAGP)
gliosis  (IAGP)
increased blood urea nitrogen level  (IAGP)
increased circulating creatinine level  (IAGP)
increased circulating parathyroid hormone level  (IAGP)
increased circulating phosphate level  (IAGP)
increased frequency of paradoxical sleep  (IAGP)
increased grip strength  (IEA)
increased kidney apoptosis  (IAGP)
increased renal tubule apoptosis  (IAGP)
iris synechia  (IEA)
kidney cyst  (IAGP)
kidney vascular congestion  (IAGP)
muscle spasm  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
ocular hypertension  (IAGP)
optic nerve atrophy  (IAGP)
optic nerve cupping  (IAGP)
optic nerve degeneration  (IAGP)
patent ductus arteriosus  (IAGP)
polydactyly  (IAGP)
postaxial polydactyly  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
pulmonary vascular congestion  (IAGP)
retina ganglion cell degeneration  (IAGP)
scaly skin  (IAGP)
small kidney  (IAGP)
thin retina inner plexiform layer  (IAGP)
tremors  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Mutations in TFAP2B cause Char syndrome, a familial form of patent ductus arteriosus. Satoda M, etal., Nat Genet. 2000 May;25(1):42-6.
12. The transcription factor AP-2beta causes cell enlargement and insulin resistance in 3T3-L1 adipocytes. Tao Y, etal., Endocrinology. 2006 Apr;147(4):1685-96. Epub 2005 Dec 22.
13. Chromosomal mapping of the human and mouse homologues of two new members of the AP-2 family of transcription factors. Williamson JA, etal., Genomics 1996 Jul 1;35(1):262-4.
Additional References at PubMed
PMID:2833704   PMID:7555706   PMID:7615634   PMID:8989526   PMID:9271117   PMID:9758708   PMID:9765260   PMID:9918694   PMID:10349636   PMID:10464095   PMID:10847586   PMID:11042159  
PMID:11076861   PMID:11319856   PMID:11553286   PMID:11694877   PMID:11940672   PMID:12466138   PMID:12504852   PMID:12694203   PMID:12695560   PMID:12711551   PMID:12749383   PMID:14572467  
PMID:15253936   PMID:15940393   PMID:16141072   PMID:16141073   PMID:16354917   PMID:16516881   PMID:16602821   PMID:16672719   PMID:16919269   PMID:16954217   PMID:17444492   PMID:17525748  
PMID:17724084   PMID:17911046   PMID:18159948   PMID:18287559   PMID:18424435   PMID:18635823   PMID:18691547   PMID:19022887   PMID:19141316   PMID:19463158   PMID:19749747   PMID:20059953  
PMID:20097161   PMID:20457670   PMID:20510229   PMID:20875861   PMID:20960542   PMID:21194568   PMID:21267068   PMID:21345437   PMID:21424113   PMID:21539825   PMID:21677750   PMID:21829553  
PMID:21858141   PMID:21873635   PMID:22325097   PMID:22342504   PMID:22411557   PMID:22510988   PMID:22639370   PMID:22988430   PMID:23362348   PMID:23616538   PMID:24073291   PMID:24184637  
PMID:24507192   PMID:24550361   PMID:24790087   PMID:24952961   PMID:25187989   PMID:25313862   PMID:25661788   PMID:25964075   PMID:25966682   PMID:26277217   PMID:26949938   PMID:26968737  
PMID:27259519   PMID:27301906   PMID:27385012   PMID:27483349   PMID:27820600   PMID:27984181   PMID:28249010   PMID:28253399   PMID:28277615   PMID:28760814   PMID:28893947   PMID:28912684  
PMID:29122676   PMID:29229773   PMID:29262337   PMID:29445148   PMID:29467543   PMID:29715367   PMID:29804851   PMID:29922981   PMID:30127719   PMID:30786278   PMID:31336386   PMID:31399471  
PMID:31638440   PMID:31924792   PMID:32353428   PMID:32553120   PMID:32769099   PMID:32857879   PMID:32878901   PMID:32986815   PMID:33328221   PMID:33460639   PMID:33482080   PMID:34445433  
PMID:34822722   PMID:35108221   PMID:35245348   PMID:35333176   PMID:35451473   PMID:35468900   PMID:35781558   PMID:35831953   PMID:35974052   PMID:36497119   PMID:36749647   PMID:36867129  
PMID:37198238   PMID:38063857   PMID:38113115   PMID:38355793   PMID:38413970   PMID:39052671  


Genomics

Comparative Map Data
Tfap2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39119,279,132 - 19,309,071 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl119,279,138 - 19,308,800 (+)EnsemblGRCm39 Ensembl
GRCm38119,208,908 - 19,238,845 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl119,208,914 - 19,238,576 (+)EnsemblGRCm38mm10GRCm38
MGSCv37119,198,995 - 19,228,815 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36119,194,128 - 19,223,948 (+)NCBIMGSCv36mm8
Celera119,103,515 - 19,133,268 (+)NCBICelera
Cytogenetic Map1A3NCBI
cM Map16.19NCBI
TFAP2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38650,818,355 - 50,847,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl650,818,723 - 50,847,619 (+)EnsemblGRCh38hg38GRCh38
GRCh37650,786,584 - 50,815,332 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36650,894,398 - 50,923,285 (+)NCBINCBI36Build 36hg18NCBI36
Build 34650,894,541 - 50,919,634NCBI
Celera652,342,514 - 52,371,233 (+)NCBICelera
Cytogenetic Map6p12.3NCBI
HuRef650,517,924 - 50,546,498 (+)NCBIHuRef
CHM1_1650,789,288 - 50,818,174 (+)NCBICHM1_1
T2T-CHM13v2.0650,660,443 - 50,690,369 (+)NCBIT2T-CHM13v2.0
Tfap2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8929,282,703 - 29,312,568 (+)NCBIGRCr8
mRatBN7.2921,786,251 - 21,816,054 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl921,786,258 - 21,814,520 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx930,275,269 - 30,304,651 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0935,415,401 - 35,444,816 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0933,717,660 - 33,747,055 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0925,410,669 - 25,440,568 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl925,410,669 - 25,440,411 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0924,271,604 - 24,302,855 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4918,052,402 - 18,082,202 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1918,049,775 - 18,079,184 (+)NCBI
Celera919,374,332 - 19,403,772 (+)NCBICelera
Cytogenetic Map9q13NCBI
Tfap2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554117,142,607 - 7,170,467 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554117,143,095 - 7,171,285 (-)NCBIChiLan1.0ChiLan1.0
TFAP2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2565,292,098 - 65,635,311 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1661,157,412 - 61,512,510 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0650,376,157 - 50,406,740 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1651,635,899 - 51,664,691 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl651,635,899 - 51,664,691 (+)Ensemblpanpan1.1panPan2
TFAP2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11218,544,176 - 18,574,300 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1218,544,446 - 18,572,902 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1218,436,730 - 18,462,495 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01219,041,005 - 19,071,021 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1219,041,155 - 19,069,637 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11218,549,889 - 18,575,642 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01218,654,100 - 18,679,842 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01218,791,560 - 18,817,345 (+)NCBIUU_Cfam_GSD_1.0
Tfap2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494654,075,431 - 54,104,213 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364769,857,773 - 9,884,784 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364769,855,992 - 9,884,788 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TFAP2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl744,745,827 - 44,770,606 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1744,745,653 - 44,774,563 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2751,206,179 - 51,235,198 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TFAP2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11721,599,570 - 21,629,757 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1721,604,067 - 21,628,489 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604450,760,129 - 50,788,887 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tfap2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248555,355,239 - 5,381,477 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248555,353,347 - 5,381,454 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2932
Count of miRNA genes:658
Interacting mature miRNAs:847
Transcripts:ENSMUST00000027059, ENSMUST00000064976
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1301011Cplaq4_mcircadian period of locomotor activity 4 (mouse)Not determined1967344243673601Mouse
1301073Orch5_mautoimmune orchitis resistance 5 (mouse)Not determined11906535153065454Mouse
1301275Sle10_msystematic lupus erythematosus susceptibility 10 (mouse)Not determined1288219436882352Mouse
15092046Wngrme1_mweek nine growth rate, maternal effect 1 (mouse)1328014237782236Mouse
1301370Adip1_madiposity 1 (mouse)Not determined1288219436882352Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
15092044Wtgrme1_mweek ten growth rate, maternal effect 1 (mouse)1328014237782236Mouse
1301240Sluc15_msusceptibility to lung cancer 15 (mouse)Not determined11906535153065454Mouse
1301471Obq2_mobesity QTL 2 (mouse)Not determined1394162037941887Mouse
14700685Civq2_mcerebral infarct volume QTL 2 (mouse)11134048245340482Mouse
1301756Pgia1_mproteoglycan induced arthritis 1 (mouse)Not determined11906535153065454Mouse
1301891Alcp25_malcohol preference locus 25 (mouse)Not determined1125203185Mouse
1300834Cia20_mcollagen induced arthritis 20 (mouse)Not determined1125203185Mouse
15092055Lgrme1_mlate growth rate, maternal effect 1 (mouse)1328014237782236Mouse
4141646Fecq3_mfecundity QTL 3 (mouse)Not determined11291692026517685Mouse
15092050Wsegrme1_mweek seven growth rate, maternal effect 1 (mouse)1328014237782236Mouse
15092051Wegrme1_mweek eight growth rate, maternal effect 1 (mouse)1328014237782236Mouse
15092048Wsigrme1_mweek six growth rate, maternal effect 1 (mouse)1328014237782236Mouse
1301482Morph1_mmorphine antinociception 1 (mouse)Not determined1130367747Mouse
10043970Obq23_mobesity QTL 23 (mouse)Not determined1501266539012665Mouse
10412226Alpq4_malcohol preference QTL 4 (mouse)Not determined1122976684Mouse

Markers in Region
Tcfap2b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37119,224,356 - 19,224,841UniSTSGRCm37
Celera119,128,811 - 19,129,296UniSTS
Cytogenetic Map1A2-A4UniSTS
cM Map1 UniSTS
cM Map16.19UniSTS
AI606113  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38119,238,212 - 19,238,292UniSTSGRCm38
MGSCv37119,228,293 - 19,228,373UniSTSGRCm37
Celera119,132,746 - 19,132,826UniSTS
Cytogenetic Map1A2-A4UniSTS
Whitehead/MRC_RH1321.15UniSTS
Tcfap2b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38119,234,275 - 19,234,760UniSTSGRCm38
MGSCv37119,224,356 - 19,224,841UniSTSGRCm37
Celera119,128,811 - 19,129,296UniSTS
Cytogenetic Map1A2-A4UniSTS
Tcfap2b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1A2-A4UniSTS
cM Map16.19UniSTS
cM Map1 UniSTS
Tcfap2b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1A2-A4UniSTS
Tcfap2b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1A2-A4UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001025305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001286340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006495491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006495494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006495495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC132356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK005128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK017373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X78197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000027059   ⟹   ENSMUSP00000027059
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl119,279,138 - 19,308,800 (+)Ensembl
GRCm38.p6 Ensembl119,208,914 - 19,238,576 (+)Ensembl
Ensembl Acc Id: ENSMUST00000064976   ⟹   ENSMUSP00000064488
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl119,282,278 - 19,304,848 (+)Ensembl
GRCm38.p6 Ensembl119,212,054 - 19,234,624 (+)Ensembl
Ensembl Acc Id: ENSMUST00000186972
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl119,284,103 - 19,289,477 (+)Ensembl
GRCm38.p6 Ensembl119,213,879 - 19,219,253 (+)Ensembl
Ensembl Acc Id: ENSMUST00000187754   ⟹   ENSMUSP00000140213
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl119,279,184 - 19,308,307 (+)Ensembl
GRCm38.p6 Ensembl119,208,960 - 19,238,083 (+)Ensembl
Ensembl Acc Id: ENSMUST00000191068
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl119,282,530 - 19,284,666 (+)Ensembl
GRCm38.p6 Ensembl119,212,306 - 19,214,442 (+)Ensembl
RefSeq Acc Id: NM_001025305   ⟹   NP_001020476
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39119,282,497 - 19,309,071 (+)NCBI
GRCm38119,212,054 - 19,238,845 (+)NCBI
MGSCv37119,198,995 - 19,228,815 (+)RGD
Celera119,103,515 - 19,133,379 (+)NCBI
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001286340   ⟹   NP_001273269
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39119,279,371 - 19,309,071 (+)NCBI
GRCm38119,208,914 - 19,238,845 (+)NCBI
Celera119,103,515 - 19,133,379 (+)NCBI
Sequence:
RefSeq Acc Id: NM_009334   ⟹   NP_033360
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39119,279,371 - 19,309,071 (+)NCBI
GRCm38119,208,914 - 19,238,845 (+)NCBI
MGSCv37119,198,995 - 19,228,815 (+)RGD
Celera119,103,515 - 19,133,379 (+)NCBI
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006495491   ⟹   XP_006495554
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39119,279,154 - 19,307,505 (+)NCBI
GRCm38119,208,930 - 19,238,577 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006495494   ⟹   XP_006495557
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39119,279,154 - 19,308,654 (+)NCBI
GRCm38119,208,930 - 19,238,577 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006495495   ⟹   XP_006495558
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39119,280,366 - 19,308,800 (+)NCBI
GRCm38119,210,142 - 19,238,576 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030252835   ⟹   XP_030108695
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39119,279,132 - 19,307,505 (+)NCBI
GRCm38119,208,908 - 19,238,577 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030252837   ⟹   XP_030108697
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39119,279,501 - 19,308,800 (+)NCBI
GRCm38119,209,277 - 19,238,576 (+)NCBI
Sequence:
RefSeq Acc Id: NP_033360   ⟸   NM_009334
- Peptide Label: isoform 1
- UniProtKB: Q8CEP1 (UniProtKB/Swiss-Prot),   Q61313 (UniProtKB/Swiss-Prot),   Q8CCV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001020476   ⟸   NM_001025305
- Peptide Label: isoform 2
- UniProtKB: E9Q5N4 (UniProtKB/TrEMBL),   Q8CCV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273269   ⟸   NM_001286340
- Peptide Label: isoform 3
- UniProtKB: Q8CE69 (UniProtKB/TrEMBL),   Q8CCV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006495554   ⟸   XM_006495491
- Peptide Label: isoform X1
- UniProtKB: Q8CCV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006495557   ⟸   XM_006495494
- Peptide Label: isoform X2
- UniProtKB: Q8CCV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006495558   ⟸   XM_006495495
- Peptide Label: isoform X4
- UniProtKB: Q8CCV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030108695   ⟸   XM_030252835
- Peptide Label: isoform X3
- UniProtKB: Q8CCV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030108697   ⟸   XM_030252837
- Peptide Label: isoform X4
- UniProtKB: Q8CCV4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000027059   ⟸   ENSMUST00000027059
Ensembl Acc Id: ENSMUSP00000140213   ⟸   ENSMUST00000187754
Ensembl Acc Id: ENSMUSP00000064488   ⟸   ENSMUST00000064976
Protein Domains
Transcription factor AP-2 C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61313-F1-model_v2 AlphaFold Q61313 1-459 view protein structure

Promoters
RGD ID:6818598
Promoter ID:MM_KWN:215
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:NM_001025305,   UC007AKS.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36119,201,281 - 19,202,232 (+)MPROMDB
RGD ID:6873256
Promoter ID:EPDNEW_M79
Type:multiple initiation site
Name:Tfap2b_1
Description:Mus musculus transcription factor AP-2 beta , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M80  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38119,211,968 - 19,212,028EPDNEW
RGD ID:6873258
Promoter ID:EPDNEW_M80
Type:single initiation site
Name:Tfap2b_2
Description:Mus musculus transcription factor AP-2 beta , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M79  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38119,212,273 - 19,212,333EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:104672 AgrOrtholog
Ensembl Genes ENSMUSG00000025927 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000027059 ENTREZGENE
  ENSMUST00000027059.11 UniProtKB/Swiss-Prot
  ENSMUST00000064976 ENTREZGENE
  ENSMUST00000064976.6 UniProtKB/TrEMBL
  ENSMUST00000187754 ENTREZGENE
  ENSMUST00000187754.7 UniProtKB/TrEMBL
InterPro TF_AP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_AP2_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_AP2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21419 UniProtKB/Swiss-Prot
MGD MGI:104672 ENTREZGENE
NCBI Gene 21419 ENTREZGENE
PANTHER PTHR10812 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10812:SF14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TF_AP-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tfap2b PhenoGen
PRINTS AP2BTNSCPFCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AP2TNSCPFCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt AP2B_MOUSE UniProtKB/Swiss-Prot
  E9Q5N4 ENTREZGENE, UniProtKB/TrEMBL
  Q3UVE9_MOUSE UniProtKB/TrEMBL
  Q61313 ENTREZGENE
  Q8CBL0_MOUSE UniProtKB/TrEMBL
  Q8CCV4 ENTREZGENE, UniProtKB/TrEMBL
  Q8CE69 ENTREZGENE, UniProtKB/TrEMBL
  Q8CEP1 ENTREZGENE
UniProt Secondary Q8CEP1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-10-25 Tfap2b  transcription factor AP-2 beta  Tcfap2b  transcription factor AP-2 beta  Symbol and/or name change 5135510 APPROVED