Inpp4a (inositol polyphosphate-4-phosphatase type I A) - Rat Genome Database

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Gene: Inpp4a (inositol polyphosphate-4-phosphatase type I A) Rattus norvegicus
Analyze
Symbol: Inpp4a
Name: inositol polyphosphate-4-phosphatase type I A
RGD ID: 68386
Description: Predicted to enable phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity. Predicted to be involved in phosphatidylinositol-3-phosphate biosynthetic process. Predicted to be located in nuclear membrane; nucleoplasm; and postsynaptic density. Predicted to be active in cytoplasm. Orthologous to human INPP4A (inositol polyphosphate-4-phosphatase type I A); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: inositol polyphosphate 4-phosphatase type I; inositol polyphosphate-4-phosphatase type I 107kD; inositol polyphosphate-4-phosphatase, type 1; inositol polyphosphate-4-phosphatase, type I; inositol polyphosphate-4-phosphatase, type I, 107kD; type I inositol 3,4-bisphosphate 4-phosphatase; type I inositol-3,4-bisphosphate 4-phosphatase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2939,528,245 - 39,650,574 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl939,528,674 - 39,646,581 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx948,024,733 - 48,142,652 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0953,147,494 - 53,265,400 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0951,429,369 - 51,547,271 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0943,889,887 - 44,006,593 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl943,889,473 - 44,004,325 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0943,533,507 - 43,707,953 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4936,238,645 - 36,356,933 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1936,240,058 - 36,358,347 (+)NCBI
Celera937,284,544 - 37,400,878 (+)NCBICelera
Cytogenetic Map9q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. The isolation and characterization of cDNA encoding human and rat brain inositol polyphosphate 4-phosphatase. Norris FA, etal., J Biol Chem 1995 Jul 7;270(27):16128-33.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:8889548   PMID:20463662   PMID:30053369   PMID:30071275  


Genomics

Comparative Map Data
Inpp4a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2939,528,245 - 39,650,574 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl939,528,674 - 39,646,581 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx948,024,733 - 48,142,652 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0953,147,494 - 53,265,400 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0951,429,369 - 51,547,271 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0943,889,887 - 44,006,593 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl943,889,473 - 44,004,325 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0943,533,507 - 43,707,953 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4936,238,645 - 36,356,933 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1936,240,058 - 36,358,347 (+)NCBI
Celera937,284,544 - 37,400,878 (+)NCBICelera
Cytogenetic Map9q21NCBI
INPP4A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38298,444,587 - 98,594,392 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl298,444,854 - 98,594,392 (+)EnsemblGRCh38hg38GRCh38
GRCh37299,061,050 - 99,210,855 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36298,501,857 - 98,570,614 (+)NCBINCBI36Build 36hg18NCBI36
Build 34298,519,930 - 98,662,684NCBI
Celera293,265,040 - 93,411,219 (+)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef292,826,490 - 92,972,083 (+)NCBIHuRef
CHM1_1299,065,634 - 99,211,815 (+)NCBICHM1_1
T2T-CHM13v2.0298,902,886 - 99,052,718 (+)NCBIT2T-CHM13v2.0
Inpp4a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39137,338,908 - 37,449,821 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl137,338,946 - 37,449,817 (+)EnsemblGRCm39 Ensembl
GRCm38137,299,827 - 37,410,740 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl137,299,865 - 37,410,736 (+)EnsemblGRCm38mm10GRCm38
MGSCv37137,356,738 - 37,467,581 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36137,302,465 - 37,352,805 (+)NCBIMGSCv36mm8
Celera137,079,390 - 37,192,754 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map115.46NCBI
Inpp4a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554704,930,568 - 5,040,383 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554704,930,568 - 5,040,153 (+)NCBIChiLan1.0ChiLan1.0
INPP4A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan12A29,857,185 - 30,002,660 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A100,720,587 - 100,867,228 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A99,355,307 - 99,499,350 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A99,428,904 - 99,499,350 (+)Ensemblpanpan1.1panPan2
INPP4A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11044,086,533 - 44,221,225 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1044,089,025 - 44,145,506 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1044,008,800 - 44,143,763 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01044,959,356 - 45,094,368 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1044,959,356 - 45,094,231 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11044,669,735 - 44,804,682 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01044,960,705 - 45,095,469 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01045,136,428 - 45,271,376 (-)NCBIUU_Cfam_GSD_1.0
Inpp4a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629284,307,312 - 84,439,129 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367441,629,438 - 1,693,141 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049367441,629,432 - 1,692,069 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INPP4A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl355,711,031 - 55,834,367 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1355,711,025 - 55,779,579 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2358,266,124 - 58,307,943 (-)NCBISscrofa10.2Sscrofa10.2susScr3
INPP4A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1142,161,649 - 2,306,023 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl142,235,510 - 2,302,858 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041169,681,423 - 169,826,862 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Inpp4a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247493,574,625 - 3,632,581 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247493,508,135 - 3,632,581 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Inpp4a
766 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:484
Count of miRNA genes:160
Interacting mature miRNAs:178
Transcripts:ENSRNOT00000024152, ENSRNOT00000024330
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
724543Cm20Cardiac mass QTL 203.9heart mass (VT:0007028)calculated heart weight (CMO:0000073)91696139840594091Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)92213332249968732Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)92375402458157242Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat

Markers in Region
D9Rat189  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2939,584,434 - 39,584,583 (+)MAPPERmRatBN7.2
Rnor_6.0943,945,642 - 43,945,788NCBIRnor6.0
Rnor_5.0943,589,412 - 43,589,558UniSTSRnor5.0
RGSC_v3.4936,295,591 - 36,295,738RGDRGSC3.4
RGSC_v3.4936,295,592 - 36,295,738UniSTSRGSC3.4
RGSC_v3.1936,297,005 - 36,297,152RGD
Celera937,340,295 - 37,340,441UniSTS
FHH x ACI Map926.82UniSTS
FHH x ACI Map926.82RGD
Cytogenetic Map9q21UniSTS
D9Rat188  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2939,538,347 - 39,538,572 (+)MAPPERmRatBN7.2
Rnor_6.0943,899,561 - 43,899,785NCBIRnor6.0
Rnor_5.0943,543,203 - 43,543,427UniSTSRnor5.0
RGSC_v3.4936,248,318 - 36,248,543RGDRGSC3.4
RGSC_v3.4936,248,319 - 36,248,543UniSTSRGSC3.4
RGSC_v3.1936,249,732 - 36,249,957RGD
Celera937,294,218 - 37,294,442UniSTS
FHH x ACI Map926.86UniSTS
FHH x ACI Map926.86RGD
Cytogenetic Map9q21UniSTS
RH139511  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2939,646,224 - 39,646,408 (+)MAPPERmRatBN7.2
Rnor_6.0944,006,237 - 44,006,420NCBIRnor6.0
Rnor_5.0943,707,597 - 43,707,780UniSTSRnor5.0
RGSC_v3.4936,356,577 - 36,356,760UniSTSRGSC3.4
Celera937,400,522 - 37,400,705UniSTS
RH 3.4 Map9369.7UniSTS
Cytogenetic Map9q21UniSTS
BF400233  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2939,642,932 - 39,643,140 (+)MAPPERmRatBN7.2
Rnor_6.0944,003,005 - 44,003,212NCBIRnor6.0
Rnor_5.0943,704,317 - 43,704,524UniSTSRnor5.0
RGSC_v3.4936,353,137 - 36,353,344UniSTSRGSC3.4
Celera937,397,198 - 37,397,405UniSTS
RH 3.4 Map9367.8UniSTS
Cytogenetic Map9q21UniSTS
BF401404  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2939,637,041 - 39,637,286 (+)MAPPERmRatBN7.2
Rnor_6.0943,997,114 - 43,997,358NCBIRnor6.0
Rnor_5.0943,698,426 - 43,698,670UniSTSRnor5.0
RGSC_v3.4936,347,246 - 36,347,490UniSTSRGSC3.4
Celera937,391,307 - 37,391,551UniSTS
RH 3.4 Map9369.2UniSTS
Cytogenetic Map9q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 13 17 1 18 1 2 2 72 22 34 11 2
Low 3 30 40 40 1 40 6 9 2 13 7 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005488970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005488971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC125939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC133270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ205789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB584080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB614071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB758981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB761394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO395558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO397336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U26397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000024330   ⟹   ENSRNOP00000024330
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl939,528,674 - 39,640,164 (+)Ensembl
Rnor_6.0 Ensembl943,889,473 - 44,004,325 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093887   ⟹   ENSRNOP00000085223
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl939,528,674 - 39,646,581 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000096431   ⟹   ENSRNOP00000093364
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl939,528,674 - 39,646,581 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000106785   ⟹   ENSRNOP00000087324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl939,591,765 - 39,646,581 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000110836   ⟹   ENSRNOP00000083933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl939,528,674 - 39,646,581 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116841   ⟹   ENSRNOP00000090042
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl939,528,674 - 39,646,581 (+)Ensembl
RefSeq Acc Id: NM_031002   ⟹   NP_112264
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,674 - 39,646,583 (+)NCBI
Rnor_6.0943,889,887 - 44,006,593 (+)NCBI
Rnor_5.0943,533,507 - 43,707,953 (+)NCBI
RGSC_v3.4936,238,645 - 36,356,933 (+)RGD
Celera937,284,544 - 37,400,878 (+)RGD
Sequence:
RefSeq Acc Id: XM_039084224   ⟹   XP_038940152
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,640,174 (+)NCBI
RefSeq Acc Id: XM_039084225   ⟹   XP_038940153
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,640,174 (+)NCBI
RefSeq Acc Id: XM_039084226   ⟹   XP_038940154
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,640,174 (+)NCBI
RefSeq Acc Id: XM_039084227   ⟹   XP_038940155
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,640,174 (+)NCBI
RefSeq Acc Id: XM_039084228   ⟹   XP_038940156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,640,174 (+)NCBI
RefSeq Acc Id: XM_039084229   ⟹   XP_038940157
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,640,174 (+)NCBI
RefSeq Acc Id: XM_039084230   ⟹   XP_038940158
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,646,587 (+)NCBI
RefSeq Acc Id: XM_039084231   ⟹   XP_038940159
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,644,056 (+)NCBI
RefSeq Acc Id: XM_039084232   ⟹   XP_038940160
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,650,574 (+)NCBI
RefSeq Acc Id: XM_039084233   ⟹   XP_038940161
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,644,056 (+)NCBI
RefSeq Acc Id: XM_039084234   ⟹   XP_038940162
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,639,375 (+)NCBI
RefSeq Acc Id: XM_039084235   ⟹   XP_038940163
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,639,375 (+)NCBI
RefSeq Acc Id: XM_039084236   ⟹   XP_038940164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,639,375 (+)NCBI
RefSeq Acc Id: XM_039084237   ⟹   XP_038940165
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,639,375 (+)NCBI
RefSeq Acc Id: XM_039084238   ⟹   XP_038940166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,246 - 39,644,755 (+)NCBI
RefSeq Acc Id: XM_039084239   ⟹   XP_038940167
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,644,056 (+)NCBI
RefSeq Acc Id: XM_039084240   ⟹   XP_038940168
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,246 - 39,644,056 (+)NCBI
RefSeq Acc Id: XM_039084241   ⟹   XP_038940169
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,246 - 39,644,056 (+)NCBI
RefSeq Acc Id: XM_039084242   ⟹   XP_038940170
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,640,174 (+)NCBI
RefSeq Acc Id: XR_005488970
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,245 - 39,624,291 (+)NCBI
RefSeq Acc Id: XR_005488971
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2939,528,246 - 39,624,291 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_112264   ⟸   NM_031002
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000024330   ⟸   ENSRNOT00000024330
RefSeq Acc Id: XP_038940160   ⟸   XM_039084232
- Peptide Label: isoform X7
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038940158   ⟸   XM_039084230
- Peptide Label: isoform X5
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038940159   ⟸   XM_039084231
- Peptide Label: isoform X6
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot),   A0A8I6ACW4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038940167   ⟸   XM_039084239
- Peptide Label: isoform X14
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038940161   ⟸   XM_039084233
- Peptide Label: isoform X8
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot),   A0A8I5ZYR7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038940154   ⟸   XM_039084226
- Peptide Label: isoform X1
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038940152   ⟸   XM_039084224
- Peptide Label: isoform X1
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038940157   ⟸   XM_039084229
- Peptide Label: isoform X4
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot),   A0A8I6A0Y3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038940155   ⟸   XM_039084227
- Peptide Label: isoform X2
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038940156   ⟸   XM_039084228
- Peptide Label: isoform X3
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038940170   ⟸   XM_039084242
- Peptide Label: isoform X17
- UniProtKB: A0A8I6A712 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038940153   ⟸   XM_039084225
- Peptide Label: isoform X1
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038940162   ⟸   XM_039084234
- Peptide Label: isoform X9
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot),   D3ZBL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038940164   ⟸   XM_039084236
- Peptide Label: isoform X11
- UniProtKB: A0A8I6A0Y3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038940163   ⟸   XM_039084235
- Peptide Label: isoform X10
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038940165   ⟸   XM_039084237
- Peptide Label: isoform X12
- UniProtKB: A0A8I6A0Y3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038940166   ⟸   XM_039084238
- Peptide Label: isoform X13
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038940168   ⟸   XM_039084240
- Peptide Label: isoform X15
- UniProtKB: Q62784 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038940169   ⟸   XM_039084241
- Peptide Label: isoform X16
- UniProtKB: A0A8I6A0Y3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000090042   ⟸   ENSRNOT00000116841
RefSeq Acc Id: ENSRNOP00000087324   ⟸   ENSRNOT00000106785
RefSeq Acc Id: ENSRNOP00000093364   ⟸   ENSRNOT00000096431
RefSeq Acc Id: ENSRNOP00000083933   ⟸   ENSRNOT00000110836
RefSeq Acc Id: ENSRNOP00000085223   ⟸   ENSRNOT00000093887
Protein Domains
C2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62784-F1-model_v2 AlphaFold Q62784 1-939 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68386 AgrOrtholog
BioCyc Gene G2FUF-27790 BioCyc
BioCyc Pathway PWY-6368 [3-phosphoinositide degradation] BioCyc
Ensembl Genes ENSRNOG00000017660 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000024330 ENTREZGENE
  ENSRNOP00000024330.8 UniProtKB/TrEMBL
  ENSRNOP00000083933 ENTREZGENE
  ENSRNOP00000083933.1 UniProtKB/TrEMBL
  ENSRNOP00000085223 ENTREZGENE
  ENSRNOP00000085223.1 UniProtKB/TrEMBL
  ENSRNOP00000087324.1 UniProtKB/TrEMBL
  ENSRNOP00000090042 ENTREZGENE
  ENSRNOP00000090042.1 UniProtKB/TrEMBL
  ENSRNOP00000093364.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024330 ENTREZGENE
  ENSRNOT00000024330.9 UniProtKB/TrEMBL
  ENSRNOT00000093887 ENTREZGENE
  ENSRNOT00000093887.1 UniProtKB/TrEMBL
  ENSRNOT00000096431.1 UniProtKB/TrEMBL
  ENSRNOT00000106785.1 UniProtKB/TrEMBL
  ENSRNOT00000110836 ENTREZGENE
  ENSRNOT00000110836.1 UniProtKB/TrEMBL
  ENSRNOT00000116841 ENTREZGENE
  ENSRNOT00000116841.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INPP4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:80849 UniProtKB/Swiss-Prot
NCBI Gene 80849 ENTREZGENE
PANTHER INOSITOL POLYPHOSPHATE-4-PHOSPHATASE TYPE I A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12187 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Inpp4a PhenoGen
PROSITE PS50004 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC218390
UniProt A0A8I5ZYR7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A0Y3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A712 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ACW4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AIL8_RAT UniProtKB/TrEMBL
  A6ING7_RAT UniProtKB/TrEMBL
  D3ZBL5 ENTREZGENE, UniProtKB/TrEMBL
  INP4A_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-21 Inpp4a  inositol polyphosphate-4-phosphatase type I A  Inpp4a  inositol polyphosphate-4-phosphatase, type I  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-05-03 Inpp4a  inositol polyphosphate-4-phosphatase, type I  Inpp4a  inositol polyphosphate-4-phosphatase, type 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Inpp4a  inositol polyphosphate-4-phosphatase, type 1      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in brain, heart, skeletal muscle, and spleen 68266
gene_protein 939 amino acids 68266