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Gene: Ptprs (protein tyrosine phosphatase, receptor type, S) Rattus norvegicus
Symbol: Ptprs
Name: protein tyrosine phosphatase, receptor type, S
Description: Exhibits protein tyrosine phosphatase activity. Involved in regulation of postsynaptic density assembly; regulation of presynapse assembly; and synaptic membrane adhesion. Localizes to the glutamatergic synapse; integral component of synaptic membrane; and integral component of synaptic vesicle membrane. Orthologous to human PTPRS (protein tyrosine phosphatase receptor type S); INTERACTS WITH (RS)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
Also known as: LAR-PTP2; Larptp2; leukocyte common antigen-related protein-tyrosine phosphatase 2; leukocyte common antigen-related proten-tyrosine phosphatase 2; MGC124537; protein tyrosine phosphatase, receptor type, D; Ptprd; Ptpsigma; Ptpsigma.; R-PTP-S; R-PTP-sigma; receptor-type tyrosine-protein phosphatase S; receptor-type tyrosine-protein phosphatase sigma; Rptpd
Homo sapiens (human) : PTPRS (protein tyrosine phosphatase receptor type S)  HGNC  Alliance
Mus musculus (house mouse) : Ptprs (protein tyrosine phosphatase, receptor type, S)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptprs (protein tyrosine phosphatase receptor type S)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPRS (protein tyrosine phosphatase receptor type S)
Canis lupus familiaris (dog) : PTPRS (protein tyrosine phosphatase receptor type S)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptprs (protein tyrosine phosphatase receptor type S)
Sus scrofa (pig) : PTPRS (protein tyrosine phosphatase receptor type S)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0910,585,360 - 10,646,205 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.099,578,004 - 9,637,940 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,203,284 - 7,264,120 (+)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ptprs
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3452
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.