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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3452
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptprs
Name: protein tyrosine phosphatase, receptor type, S
Acc ID: CHEBI:205919
Term: clobetasol
Definition: A 3-oxo-Delta(1),Delta(4)-steroid that is 16beta-methylpregna-1,4-diene-3,20-dione bearing hydroxy groups at the 11beta and 17alpha positions, fluorine at position 9, and a chlorine substituent at position 21. It is used as its 17alpha-propionate ester to treat various skin disorders, including exzema and psoriasis.
Chemical ID: MESH:D002990
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7343586480464CTDClobetasol results in decreased expression of PTPRS mRNA

PMID:27462272
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