PTPRS (protein tyrosine phosphatase receptor type S) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: PTPRS (protein tyrosine phosphatase receptor type S) Sus scrofa
Analyze
Symbol: PTPRS
Name: protein tyrosine phosphatase receptor type S
RGD ID: 14157742
Description: ENCODES a protein that exhibits protein tyrosine phosphatase activity (ortholog); INVOLVED IN cerebellum development (ortholog); cerebral cortex development (ortholog); corpus callosum development (ortholog); ASSOCIATED WITH COVID-19 (ortholog); Hearing Loss (ortholog); NATURAL KILLER CELL ENTEROPATHY (ortholog); FOUND IN cytosol (ortholog); glutamatergic synapse (ortholog); integral component of postsynaptic density membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase S; tyrosine-protein phosphatase 13
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl273,574,854 - 73,680,685 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1273,607,815 - 73,680,685 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2274,545,303 - 74,550,135 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

Genomics

Comparative Map Data
PTPRS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl273,574,854 - 73,680,685 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1273,607,815 - 73,680,685 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2274,545,303 - 74,550,135 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl195,158,495 - 5,340,812 (-)EnsemblGRCh38hg38GRCh38
GRCh38195,205,503 - 5,340,812 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37195,205,519 - 5,340,823 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36195,156,519 - 5,291,814 (-)NCBINCBI36hg18NCBI36
Build 34195,157,380 - 5,237,399NCBI
Celera195,143,031 - 5,278,326 (-)NCBI
Cytogenetic Map19p13.3NCBI
HuRef194,967,302 - 5,101,977 (-)NCBIHuRef
CHM1_1195,205,046 - 5,340,693 (-)NCBICHM1_1
Ptprs
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391756,719,426 - 56,783,526 (-)NCBIGRCm39mm39
GRCm39 Ensembl1756,719,426 - 56,783,483 (-)Ensembl
GRCm381756,412,426 - 56,476,561 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1756,412,426 - 56,476,483 (-)EnsemblGRCm38mm10GRCm38
MGSCv371756,551,849 - 56,615,903 (-)NCBIGRCm37mm9NCBIm37
MGSCv361756,046,141 - 56,110,077 (-)NCBImm8
Celera1760,758,165 - 60,822,309 (-)NCBICelera
Cytogenetic Map17DNCBI
cM Map1729.32NCBI
Ptprs
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.291,245,408 - 1,307,015 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl91,245,410 - 1,306,947 (-)Ensembl
Rnor_6.0910,585,360 - 10,646,205 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl910,603,813 - 10,645,939 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.099,578,004 - 9,637,940 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,203,284 - 7,264,120 (+)NCBICelera
Cytogenetic Map9q12NCBI
Ptprs
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554953,943,170 - 3,990,927 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554953,943,075 - 3,991,361 (+)NCBIChiLan1.0ChiLan1.0
PTPRS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1195,167,338 - 5,254,343 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl195,168,599 - 5,247,778 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0194,227,038 - 4,361,958 (-)NCBIMhudiblu_PPA_v0panPan3
PTPRS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12054,575,853 - 54,672,141 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2054,575,895 - 54,672,068 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2054,301,762 - 54,397,754 (+)NCBI
ROS_Cfam_1.02055,231,459 - 55,327,738 (+)NCBI
ROS_Cfam_1.0 Ensembl2055,231,447 - 55,326,993 (+)Ensembl
UMICH_Zoey_3.12054,293,104 - 54,389,219 (+)NCBI
UNSW_CanFamBas_1.02054,773,757 - 54,869,877 (+)NCBI
UU_Cfam_GSD_1.02054,971,421 - 55,067,624 (+)NCBI
Ptprs
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118214,761,700 - 214,813,370 (+)NCBI
SpeTri2.0NW_0049365883,021,418 - 3,073,080 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.164,880,942 - 5,019,654 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl64,882,223 - 4,964,919 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660813,106,747 - 3,243,187 (+)NCBIVero_WHO_p1.0
Ptprs
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248284,688,555 - 4,764,805 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 2 21 1
Low 10 4 2 3 2 2 2 2 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000031816   ⟹   ENSSSCP00000023142
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl273,574,854 - 73,680,677 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000032503   ⟹   ENSSSCP00000027741
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl273,622,409 - 73,680,679 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000088734   ⟹   ENSSSCP00000065368
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl273,574,894 - 73,680,685 (+)Ensembl
RefSeq Acc Id: XM_021084028   ⟹   XP_020939687
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1273,607,815 - 73,680,685 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020939687 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020939687   ⟸   XM_021084028
- Sequence:
RefSeq Acc Id: ENSSSCP00000065368   ⟸   ENSSSCT00000088734
RefSeq Acc Id: ENSSSCP00000023142   ⟸   ENSSSCT00000031816
RefSeq Acc Id: ENSSSCP00000027741   ⟸   ENSSSCT00000032503

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000028612 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000023142 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000027741 UniProtKB/TrEMBL
  ENSSSCP00000065368 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000031816 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000032503 UniProtKB/TrEMBL
  ENSSSCT00000088734 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTPase_domain UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
NCBI Gene PTPRS ENTREZGENE
Pfam fn3 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A5G2QMU4_PIG UniProtKB/TrEMBL
  I3LGE9_PIG UniProtKB/TrEMBL
  I3LUE2_PIG UniProtKB/TrEMBL
VGNC ID VGNC:91994 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-19 PTPRS  protein tyrosine phosphatase receptor type S    protein tyrosine phosphatase, receptor type S  Symbol and/or name change 5135510 APPROVED