Slc25a27 (solute carrier family 25, member 27) - Rat Genome Database

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Gene: Slc25a27 (solute carrier family 25, member 27) Rattus norvegicus
Analyze
Symbol: Slc25a27
Name: solute carrier family 25, member 27
RGD ID: 620787
Description: Predicted to enable chloride transmembrane transporter activity; protein homodimerization activity; and proton transmembrane transporter activity. Involved in several processes, including intracellular triglyceride homeostasis; negative regulation of mitochondrial calcium ion concentration; and negative regulation of mitochondrial membrane potential. Located in apical part of cell and neuronal cell body. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human SLC25A27 (solute carrier family 25 member 27); INTERACTS WITH 1,2,4-trimethylbenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: mitochondrial uncoupling protein 4; Ucp4; uncoupling protein UCP-4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8924,804,183 - 24,831,219 (+)NCBIGRCr8
mRatBN7.2917,306,898 - 17,333,942 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl917,307,023 - 17,332,731 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx925,896,938 - 25,922,631 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0930,971,478 - 30,997,179 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0929,260,717 - 29,286,408 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0919,880,468 - 19,907,506 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl919,880,473 - 19,907,458 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,758,140 - 18,785,173 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4913,002,823 - 13,028,534 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1913,000,144 - 13,025,851 (+)NCBI
Celera915,030,555 - 15,056,284 (+)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. UCP4 overexpression improves fatty acid oxidation and insulin sensitivity in L6 myocytes. Gao CL, etal., J Bioenerg Biomembr. 2011 Apr;43(2):109-18. doi: 10.1007/s10863-011-9344-9. Epub 2011 May 24.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Mitochondrial UCP4 mediates an adaptive shift in energy metabolism and increases the resistance of neurons to metabolic and oxidative stress. Liu D, etal., Neuromolecular Med. 2006;8(3):389-414.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Comparative analysis of uncoupling protein 4 distribution in various tissues under physiological conditions and during development. Smorodchenko A, etal., Biochim Biophys Acta. 2009 Oct;1788(10):2309-19. Epub 2009 Jul 30.
11. Role of mitochondrial uncoupling protein 4 in rat inner ear. Smorodchenko A, etal., Mol Cell Neurosci. 2011 Aug;47(4):244-53. Epub 2011 Mar 11.
12. Mitochondrial proton leak and the uncoupling protein 1 homologues. Stuart JA, etal., Biochim Biophys Acta 2001 Mar 1;1504(1):144-58.
13. Domoic acid induced spinal cord lesions in adult mice: evidence for the possible molecular pathways of excitatory amino acids in spinal cord lesions. Xu R, etal., Neurotoxicology. 2008 Jul;29(4):700-7. Epub 2008 May 1.
14. Synergistic association of mitochondrial uncoupling protein (UCP) genes with schizophrenia. Yasuno K, etal., Am J Med Genet B Neuropsychiatr Genet. 2007 Mar 5;144B(2):250-3.
15. Overexpression of uncoupling protein 4 promotes proliferation and inhibits apoptosis and differentiation of preadipocytes. Zhang M, etal., Life Sci. 2006 Sep 5;79(15):1428-35. Epub 2006 Apr 27.
Additional References at PubMed
PMID:10025957   PMID:14651853   PMID:15464300   PMID:18614015   PMID:18992805   PMID:23266757   PMID:23800309   PMID:26934480  


Genomics

Comparative Map Data
Slc25a27
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8924,804,183 - 24,831,219 (+)NCBIGRCr8
mRatBN7.2917,306,898 - 17,333,942 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl917,307,023 - 17,332,731 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx925,896,938 - 25,922,631 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0930,971,478 - 30,997,179 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0929,260,717 - 29,286,408 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0919,880,468 - 19,907,506 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl919,880,473 - 19,907,458 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,758,140 - 18,785,173 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4913,002,823 - 13,028,534 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1913,000,144 - 13,025,851 (+)NCBI
Celera915,030,555 - 15,056,284 (+)NCBICelera
Cytogenetic Map9q13NCBI
SLC25A27
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38646,652,975 - 46,678,190 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl646,652,915 - 46,678,190 (+)EnsemblGRCh38hg38GRCh38
GRCh37646,620,712 - 46,645,927 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36646,728,638 - 46,753,886 (+)NCBINCBI36Build 36hg18NCBI36
Build 34646,728,638 - 46,752,935NCBI
Celera648,173,194 - 48,198,451 (+)NCBICelera
Cytogenetic Map6p12.3NCBI
HuRef646,343,936 - 46,369,200 (+)NCBIHuRef
CHM1_1646,624,101 - 46,649,353 (+)NCBICHM1_1
T2T-CHM13v2.0646,490,625 - 46,515,839 (+)NCBIT2T-CHM13v2.0
Slc25a27
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391743,948,630 - 43,978,105 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1743,952,782 - 43,978,105 (-)EnsemblGRCm39 Ensembl
GRCm381743,637,739 - 43,667,214 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1743,641,891 - 43,667,214 (-)EnsemblGRCm38mm10GRCm38
MGSCv371743,778,849 - 43,803,964 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361743,104,955 - 43,130,070 (-)NCBIMGSCv36mm8
Celera1747,064,995 - 47,089,821 (-)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1719.75NCBI
Slc25a27
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543711,497,308 - 11,514,208 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543711,497,308 - 11,514,208 (+)NCBIChiLan1.0ChiLan1.0
SLC25A27
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2561,148,173 - 61,175,591 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1657,014,392 - 57,041,789 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0646,235,558 - 46,287,015 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1647,507,685 - 47,556,964 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl647,504,836 - 47,532,655 (+)Ensemblpanpan1.1panPan2
SLC25A27
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11214,818,385 - 14,846,688 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1214,818,541 - 14,846,700 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1214,849,780 - 14,872,673 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01215,318,189 - 15,346,646 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1215,318,244 - 15,343,998 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11214,833,979 - 14,856,823 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01214,922,871 - 14,945,764 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01215,019,528 - 15,042,410 (+)NCBIUU_Cfam_GSD_1.0
Slc25a27
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494650,262,753 - 50,288,115 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647613,671,860 - 13,697,451 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647613,674,153 - 13,697,449 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A27
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl741,426,170 - 41,457,883 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1741,426,161 - 41,457,887 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2748,092,192 - 48,121,659 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC25A27
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11725,596,757 - 25,621,202 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1725,598,242 - 25,621,238 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604446,671,344 - 46,695,785 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc25a27
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475413,961,734 - 13,980,090 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475413,961,601 - 13,980,089 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc25a27
202 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:567
Count of miRNA genes:267
Interacting mature miRNAs:338
Transcripts:ENSRNOT00000052068
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
724543Cm20Cardiac mass QTL 203.9heart mass (VT:0007028)calculated heart weight (CMO:0000073)91696139840594091Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 72 2
Low 1 29 39 28 3 28 5 7 2 31 39 9 5
Below cutoff 2 14 18 13 15 13 3 4 4 2 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ300162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ300163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ300164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY512661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000052068   ⟹   ENSRNOP00000039207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl917,307,023 - 17,332,731 (+)Ensembl
Rnor_6.0 Ensembl919,880,473 - 19,907,458 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098372   ⟹   ENSRNOP00000094770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl917,308,863 - 17,332,731 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098398   ⟹   ENSRNOP00000082945
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl917,308,863 - 17,332,731 (+)Ensembl
RefSeq Acc Id: NM_053500   ⟹   NP_445952
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,308 - 24,830,017 (+)NCBI
mRatBN7.2917,307,023 - 17,332,736 (+)NCBI
Rnor_6.0919,880,593 - 19,906,304 (+)NCBI
Rnor_5.0918,758,140 - 18,785,173 (+)NCBI
RGSC_v3.4913,002,823 - 13,028,534 (+)RGD
Celera915,030,555 - 15,056,284 (+)RGD
Sequence:
RefSeq Acc Id: XM_006244610   ⟹   XP_006244672
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,183 - 24,831,219 (+)NCBI
mRatBN7.2917,306,898 - 17,328,614 (+)NCBI
Rnor_6.0919,880,468 - 19,901,907 (+)NCBI
Rnor_5.0918,758,140 - 18,785,173 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244611   ⟹   XP_006244673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,183 - 24,831,219 (+)NCBI
mRatBN7.2917,306,898 - 17,333,942 (+)NCBI
Rnor_6.0919,880,468 - 19,907,506 (+)NCBI
Rnor_5.0918,758,140 - 18,785,173 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244612   ⟹   XP_006244674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,183 - 24,831,219 (+)NCBI
mRatBN7.2917,306,898 - 17,333,942 (+)NCBI
Rnor_6.0919,880,468 - 19,907,506 (+)NCBI
Rnor_5.0918,758,140 - 18,785,173 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008766882   ⟹   XP_008765104
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,938 - 24,831,219 (+)NCBI
mRatBN7.2917,307,658 - 17,328,614 (+)NCBI
Rnor_6.0919,881,230 - 19,907,506 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039084299   ⟹   XP_038940227
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,183 - 24,831,219 (+)NCBI
mRatBN7.2917,306,898 - 17,328,614 (+)NCBI
RefSeq Acc Id: XM_039084300   ⟹   XP_038940228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,471 - 24,831,219 (+)NCBI
mRatBN7.2917,307,184 - 17,328,614 (+)NCBI
RefSeq Acc Id: XM_039084302   ⟹   XP_038940230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,805,443 - 24,831,219 (+)NCBI
mRatBN7.2917,309,099 - 17,328,614 (+)NCBI
RefSeq Acc Id: XM_039084303   ⟹   XP_038940231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,395 - 24,831,219 (+)NCBI
mRatBN7.2917,307,110 - 17,331,294 (+)NCBI
RefSeq Acc Id: XM_063267787   ⟹   XP_063123857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,475 - 24,831,219 (+)NCBI
RefSeq Acc Id: NP_445952   ⟸   NM_053500
- UniProtKB: Q9EPH7 (UniProtKB/TrEMBL),   A6JJ30 (UniProtKB/TrEMBL),   A6JJ28 (UniProtKB/TrEMBL),   F7F692 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244673   ⟸   XM_006244611
- Peptide Label: isoform X2
- UniProtKB: Q9EPH6 (UniProtKB/TrEMBL),   A0A8I6ALR4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244674   ⟸   XM_006244612
- Peptide Label: isoform X4
- UniProtKB: A6JJ28 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244672   ⟸   XM_006244610
- Peptide Label: isoform X1
- UniProtKB: Q9EPH5 (UniProtKB/TrEMBL),   A6JJ28 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765104   ⟸   XM_008766882
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000039207   ⟸   ENSRNOT00000052068
RefSeq Acc Id: XP_038940227   ⟸   XM_039084299
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038940231   ⟸   XM_039084303
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038940228   ⟸   XM_039084300
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038940230   ⟸   XM_039084302
- Peptide Label: isoform X7
RefSeq Acc Id: ENSRNOP00000094770   ⟸   ENSRNOT00000098372
RefSeq Acc Id: ENSRNOP00000082945   ⟸   ENSRNOT00000098398
RefSeq Acc Id: XP_063123857   ⟸   XM_063267787
- Peptide Label: isoform X6

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6R5J6-F1-model_v2 AlphaFold Q6R5J6 1-275 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620787 AgrOrtholog
BioCyc Gene G2FUF-28118 BioCyc
Ensembl Genes ENSRNOG00000010592 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000052068 ENTREZGENE
  ENSRNOT00000052068.4 UniProtKB/TrEMBL
  ENSRNOT00000098372.1 UniProtKB/TrEMBL
  ENSRNOT00000098398.1 UniProtKB/TrEMBL
Gene3D-CATH 1.50.40.10 UniProtKB/TrEMBL
InterPro Mitochondrial_sb/sol_carrier UniProtKB/TrEMBL
  Mt_carrier_dom UniProtKB/TrEMBL
KEGG Report rno:85262 UniProtKB/TrEMBL
NCBI Gene 85262 ENTREZGENE
PANTHER MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED UniProtKB/TrEMBL
  MITOCHONDRIAL UNCOUPLING PROTEIN 4 UniProtKB/TrEMBL
Pfam Mito_carr UniProtKB/TrEMBL
PhenoGen Slc25a27 PhenoGen
PROSITE SOLCAR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010592 RatGTEx
Superfamily-SCOP Mitoch_carrier UniProtKB/TrEMBL
UniProt A0A8I5ZVX7_RAT UniProtKB/TrEMBL
  A0A8I6ALR4 ENTREZGENE, UniProtKB/TrEMBL
  A6JJ28 ENTREZGENE, UniProtKB/TrEMBL
  A6JJ30 ENTREZGENE, UniProtKB/TrEMBL
  F7F692 ENTREZGENE, UniProtKB/TrEMBL
  Q6R5J6_RAT UniProtKB/TrEMBL
  Q9EPH5 ENTREZGENE, UniProtKB/TrEMBL
  Q9EPH6 ENTREZGENE, UniProtKB/TrEMBL
  Q9EPH7 ENTREZGENE
UniProt Secondary Q9EPH7 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Slc25a27  solute carrier family 25, member 27  Ucp4  uncoupling protein UCP-4  Symbol and Name updated 1299863 APPROVED
2002-08-07 Ucp4  uncoupling protein UCP-4      Symbol and Name status set to provisional 70820 PROVISIONAL