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Gene: Pla2g7 (phospholipase A2 group VII) Rattus norvegicus
Symbol: Pla2g7
Name: phospholipase A2 group VII
Description: Predicted to have 1-alkyl-2-acetylglycerophosphocholine esterase activity; calcium-independent phospholipase A2 activity; and phospholipid binding activity. Predicted to be involved in several processes, including plasma lipoprotein particle remodeling; platelet activating factor metabolic process; and positive regulation of monocyte chemotaxis. Localizes to the cytoplasm and extracellular space. Biomarker of nephrotic syndrome. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); glomerulonephritis (multiple); hemolytic-uremic syndrome; proteinuria (multiple); and type 2 diabetes mellitus. Orthologous to human PLA2G7 (phospholipase A2 group VII); PARTICIPATES IN ether lipid metabolic pathway; ether lipid metabolic pathway; INTERACTS WITH (RS)-amphetamine; 1-naphthyl isothiocyanate; 2,4,6-trinitrotoluene.
Type: protein-coding
Also known as: LOC301265; MGC95107; phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma); platelet-activating factor acetylhydrolase
Homo sapiens (human) : PLA2G7 (phospholipase A2 group VII)  HGNC  Alliance
Mus musculus (house mouse) : Pla2g7 (phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pla2g7 (phospholipase A2 group VII)
Pan paniscus (bonobo/pygmy chimpanzee) : PLA2G7 (phospholipase A2 group VII)
Canis lupus familiaris (dog) : PLA2G7 (phospholipase A2 group VII)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pla2g7 (phospholipase A2 group VII)
Sus scrofa (pig) : PLA2G7 (phospholipase A2 group VII)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0919,935,754 - 19,978,013 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0918,813,216 - 18,855,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4913,057,988 - 13,100,289 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1913,055,311 - 13,097,611 (-)NCBI
Celera915,085,734 - 15,127,419 (-)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Pla2g7
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310734
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.