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Gene: Lonp1 (lon peptidase 1, mitochondrial) Rattus norvegicus
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Symbol: Lonp1
Name: lon peptidase 1, mitochondrial
Description: Exhibits ATP-dependent peptidase activity. Involved in several processes, including mitochondrion organization; response to aluminum ion; and response to hypoxia. Localizes to the mitochondrial matrix. Used to study brain ischemia and ischemia. Human ortholog(s) of this gene implicated in CODAS syndrome. Orthologous to human LONP1 (lon peptidase 1, mitochondrial); INTERACTS WITH 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Lon; lon protease homolog, mitochondrial; lon protease-like protein; LONP; mitochondrial ATP-dependent protease Lon; protease, serine, 15; Prss15; serine protease 15
Orthologs:
Homo sapiens (human) : LONP1 (lon peptidase 1, mitochondrial)  HGNC  Alliance
Mus musculus (house mouse) : Lonp1 (lon peptidase 1, mitochondrial)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lonp1 (lon peptidase 1, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : LONP1 (lon peptidase 1, mitochondrial)
Canis lupus familiaris (dog) : LONP1 (lon peptidase 1, mitochondrial)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lonp1 (lon peptidase 1, mitochondrial)
Sus scrofa (pig) : LONP1 (lon peptidase 1, mitochondrial)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0910,428,853 - 10,441,180 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl910,428,853 - 10,441,177 (+)Ensembl
Rnor_5.099,425,780 - 9,438,107 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,054,065 - 7,066,392 (+)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Lonp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621598
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.