LONP1 (lon peptidase 1, mitochondrial)

Gene: LONP1 (lon peptidase 1, mitochondrial) Canis lupus familiaris

Analyze

Symbol:

LONP1

Name:

lon peptidase 1, mitochondrial

RGD ID:

12157081

Description:

ENCODES a protein that exhibits ATP-dependent peptidase activity (ortholog); insulin receptor substrate binding (ortholog); mitochondrial promoter sequence-specific DNA binding (ortholog); INVOLVED IN mitochondrion organization (ortholog); negative regulation of insulin receptor signaling pathway (ortholog); protein catabolic process (ortholog); ASSOCIATED WITH brain ischemia (ortholog); cataract (ortholog); CODAS syndrome (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

lon protease homolog, mitochondrial

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	54,312,678 - 54,334,142 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	54,312,678 - 54,334,141 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	54,039,655 - 54,060,901 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	54,968,948 - 54,989,800 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	54,968,934 - 54,989,798 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	54,031,188 - 54,052,300 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	54,511,948 - 54,532,794 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	54,708,845 - 54,730,076 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

brain ischemia (ISO)

cataract (ISO)

CODAS syndrome (ISO)

Dwarfism (ISO)

genetic disease (ISO)

ischemia (ISO)

Neurodevelopmental Disorders (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to oxidative stress (IEA)

chaperone-mediated protein complex assembly (IEA)

mitochondrion organization (IEA,ISO)

negative regulation of insulin receptor signaling pathway (ISO)

oxidation-dependent protein catabolic process (IEA)

protein catabolic process (IEA,ISO)

protein quality control for misfolded or incompletely synthesized proteins (IEA)

protein-containing complex assembly (ISO)

proteolysis (IEA,ISO)

proteolysis involved in protein catabolic process (IEA)

regulation of peptidyl-tyrosine phosphorylation (ISO)

response to aluminum ion (ISO)

response to hormone (ISO)

response to hypoxia (IEA,ISO)

Cellular Component

cytosol (IEA)

mitochondrial matrix (IEA,ISO)

mitochondrial nucleoid (IEA)

mitochondrion (IEA,ISO)

nucleoplasm (IEA)

Molecular Function

ADP binding (IEA)

ATP binding (IEA)

ATP hydrolysis activity (IEA)

ATP-dependent peptidase activity (IEA,ISO)

DNA binding (IEA)

DNA polymerase binding (IEA)

G-quadruplex DNA binding (IEA)

identical protein binding (IEA)

insulin receptor substrate binding (ISO)

mitochondrial promoter sequence-specific DNA binding (ISO)

PH domain binding (ISO)

protein binding (ISO)

sequence-specific DNA binding (IEA)

serine-type endopeptidase activity (IEA)

serine-type peptidase activity (IEA)

single-stranded DNA binding (IEA)

single-stranded RNA binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202	PMID:37756605

Genomics

Comparative Map Data

LONP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	54,312,678 - 54,334,142 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	54,312,678 - 54,334,141 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	54,039,655 - 54,060,901 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	54,968,948 - 54,989,800 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	54,968,934 - 54,989,798 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	54,031,188 - 54,052,300 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	54,511,948 - 54,532,794 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	54,708,845 - 54,730,076 (+)	NCBI		UU_Cfam_GSD_1.0

LONP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	5,691,834 - 5,720,452 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	5,691,834 - 5,720,572 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	5,691,845 - 5,720,463 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	5,642,845 - 5,671,176 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	5,642,844 - 5,671,176	NCBI
Celera	19	5,629,216 - 5,657,543 (-)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	5,452,614 - 5,480,959 (-)	NCBI		HuRef
CHM1_1	19	5,691,454 - 5,720,076 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	5,678,524 - 5,707,125 (-)	NCBI		T2T-CHM13v2.0

Lonp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	56,921,297 - 56,933,903 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	56,921,297 - 56,933,887 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	56,614,297 - 56,626,903 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	56,614,297 - 56,626,887 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	56,753,720 - 56,766,326 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	56,299,420 - 56,312,007 (-)	NCBI		MGSCv36	mm8
Celera	17	60,958,496 - 60,971,102 (-)	NCBI		Celera
Cytogenetic Map	17	D	NCBI
cM Map	17	29.42	NCBI

Lonp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	1,534,581 - 1,546,908 (-)	NCBI		GRCr8
mRatBN7.2	9	1,447,444 - 1,459,771 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	1,447,447 - 1,459,771 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	1,880,871 - 1,893,202 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	7,231,053 - 7,243,381 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	6,186,076 - 6,198,407 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	10,428,853 - 10,441,180 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	10,428,853 - 10,441,177 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	9,425,780 - 9,438,107 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	9	7,054,065 - 7,066,392 (+)	NCBI		Celera
Cytogenetic Map	9	q11	NCBI

Lonp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	3,712,199 - 3,731,301 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	3,712,173 - 3,729,556 (+)	NCBI	ChiLan1.0	ChiLan1.0

LONP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	10,088,400 - 10,115,046 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	9,314,584 - 9,341,222 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	4,709,062 - 4,735,653 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	5,644,525 - 5,670,956 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	5,644,525 - 5,670,956 (-)	Ensembl	panpan1.1		panPan2

Lonp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	214,547,848 - 214,569,438 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	3,265,512 - 3,287,181 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	3,265,344 - 3,287,035 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LONP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	73,266,258 - 73,286,773 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	73,266,310 - 73,286,774 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	73,788,290 - 73,808,755 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LONP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	5,348,968 - 5,371,521 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	5,346,426 - 5,371,507 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666081	2,731,120 - 2,753,980 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lonp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	4,494,813 - 4,516,510 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	4,494,786 - 4,516,772 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in LONP1
366 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	5	5	22	6	4	6	6	6	12	5	10	6
Low					2					3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038428957	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038504591	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038567636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038631790	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_849298	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000029820 ⟹ ENSCAFP00000027714

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	20	54,312,678 - 54,334,141 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845022906 ⟹ ENSCAFP00845017958

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	20	54,968,934 - 54,989,798 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845022947 ⟹ ENSCAFP00845017988

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	20	54,968,948 - 54,989,798 (+)	Ensembl

RefSeq Acc Id:

XM_038428957 ⟹ XP_038284885

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	20	54,968,948 - 54,989,800 (+)	NCBI

RefSeq Acc Id:

XM_038504591 ⟹ XP_038360519

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	20	54,031,188 - 54,052,300 (+)	NCBI

RefSeq Acc Id:

XM_038567636 ⟹ XP_038423564

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	20	54,708,845 - 54,730,076 (+)	NCBI

RefSeq Acc Id:

XM_038631790 ⟹ XP_038487718

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	20	54,511,948 - 54,532,794 (+)	NCBI

RefSeq Acc Id:

XM_849298 ⟹ XP_854391

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	20	54,312,678 - 54,334,142 (+)	NCBI
Dog10K_Boxer_Tasha	20	54,039,655 - 54,060,901 (+)	NCBI

Sequence:

show sequence

ATGGCGGCGGGCACAGGCTACGTGCGGCTGTGGGGTGCTGCGCGATGTTGGGCGCTGCGGCGGC
CGCTGCTGGCCGCTGCCTGGGGGCGGGTTCCGACTGCCGCCGAAACGTGGTTGCCCCGCGGCCG
GCGGGCCTGCGACGCCTCCCCTCCCTGGGCGCTGTGGGGCCGAGGCCCGGTTGCCGCGGGCCAG
TGGCGGGGACTTTGGGAGGCGAACAGCCGCGGCGGCAGTGGTGCGTTCTCCAGCGGCGAGGATG
CCTCCGAAGGCGGCGCGGAGGATGGGTCCGCGGGCGCGGGGGGCAGCGCGGGGGGCGGGGAGGG
CCCCATCATAACGGCGCTGACGCCTATGACTATTCCGGACGTATTCCCGCACCTGCCGCTCATC
GCCGTCACCCGCAACCCGGTGTTTCCGCGCTTCATCAAGATCATCGAGGTTAAAAATAAGAAGT
TGGTTGAGCTGCTAAGAAGGAAAGTCCGTCTTGCCCAGCCCTATGCTGGCGTCTTTCTGAAGAG
AGATGACAACAACGAATCTGACGTGGTTGAGAGCCTGGATGAGGTCTACCACACGGGCACGTTT
GTCCAGATCCACGAGATGCAAGACCTTGGGGACAAGCTGCGCATGATCGTCATGGGACACAGAA
GGATTCACATCAGCAGACAGCTGGAGGTGGAGCTGGAGGAGGCCGAAGCTGAAAACAAGCAGAA
GCCTCGCAGGAAGACGAAGCGGGGCAAGAAGGAGGTGGAGGAGGACCTGGGTGCCGGGCACCCG
ATGGAAATGGTGGTGGAGCCTGCTTCGGGGTCCCCCGGCGAGGTGCTCATGGTGGAAGTTGAGA
ACGTTGTCCACGAGGACTTCCAGGTCACGGAAGAAGTGAAAGCCCTGACCGCTGAGATTGTGAA
GACCATCCGTGACATCATTGCCTTGAACCCGCTCTACAGGGAGTCTGTGCTGCAAATGATGCAG
GCGGGCCAGAGGGTGGTGGACAACCCTATCTACTTGAGTGACATGGGCGCTGCCCTGACCGGAG
CCGAGTCCCACGAGCTGCAGGACGTCCTGGAGGAAACCAATATTCCCAAGCGGCTGTATAAGGC
CCTCTCCCTCCTCAAGAAGGAGTTTGAGCTGAGCAAGCTGCAGCAGCGCCTGGGGCGTGAGGTG
GAGGAGAAGATCAAGCAGACGCACCGCAAGTACCTCCTACAGGAGCAGCTGAAGATCATCAAGA
AGGAGTTGGGCCTAGAGAAGGACGACAAGGACGCCATTGAGGAGAAGTTCCGTGAGCGGCTCAA
GGAGCTTGTGGTCCCCAAGCATGTCATGGACGTGGTGGACGAGGAGCTGAGCAAGCTGGGGCTG
CTGGACAACCACTCGTCAGAGTTCAACGTCACGCGTAACTACCTGGACTGGCTGACGTCCATCC
CGTGGGGCAAGTACAGCAACGAGAACTTGGACCTGGCCCGGGCCCAGGCAGTGCTGGAGGAGGA
CCACTATGGGATGGAGGATGTCAAGAAGCGCATCCTGGAGTTCATCGCTGTCAGCCAGCTCCGA
GGCTCCACCCAGGGCAAGATCCTCTGCTTCTACGGTCCCCCTGGCGTGGGCAAGACCAGCATTG
CTCGCTCCATTGCCCGTGCCCTGAACCGAGAGTACTTCCGCTTCAGCGTCGGGGGCATGACTGA
TGTGGCTGAGATCAAAGGGCACAGGCGGACGTATGTGGGTGCTATGCCAGGAAAGATCATCCAG
TGCCTGAAGAAGACCAAGACGGAGAATCCCTTGATCCTGATAGATGAGGTGGACAAGATAGGCC
GAGGCTACCAGGGGGACCCCTCGTCAGCACTGCTCGAGCTGCTGGACCCCGAGCAGAACGCCAA
CTTTCTGGATCATTACCTGGACGTGCCTGTGGACTTGTCCAAGGTGCTGTTCATCTGCACGGCC
AATGTCACCGAGACCATCCCAGAGCCACTGAGGGACCGGATGGAGATGATCAACGTGTCTGGCT
ATGTGGCCCAGGAGAAGCTCGCCATCGCAGAGCGGTACCTGGTGCCTCAGGCCCGTGCCCTGTG
TGGCTTGGATGAGAGCAAGGCCAAGCTGTCATCAGACGTGCTGACCCTCCTCATCAAGCAGTAC
TGCCGGGAGAGTGGTGTGCGCAACCTGCAGAAGCAGGTGGAGAAGGTGTTACGGAAGTCCGCCT
ACAAGATTGTCAGTGGGGAGGCGGACCTCGTAGAGGTGACGCCAGAGAATCTGCAGGACTTTGT
GGGGAAGCCCGTGTTCACTGTGGAGCGCATGTACGATGTGACGCCCCCTGGTGTGGTCATGGGA
CTGGCCTGGACTGCCATGGGGGGCTCCACGCTGTTTGTTGAGACCTCCCCTCGGAGGCCACGAG
ACAAGGACAGCAAGGGGGACAAGGATGGAAGCCTGGAGGTGACAGGCCAGCTGGGGGACGTGAT
GAAGGAGAGTGCTCGCATCGCCTACACCTTCGCCAGGGCCTTCCTGATGCAGCATGACCCCACC
AACGACTACCTGGTGACCTCCCACATCCACCTGCACGTCCCTGAGGGCGCCACCCCCAAGGATG
GCCCAAGTGCCGGCTGCACCATTGTCACGGCCCTGCTCTCCCTGGCCATGGACCAGCCAGTACG
GCCCAACCTGGCCATGACGGGCGAGGTCTCCCTCACGGGCAAGATCCTGCCGGTGGGTGGCATC
AAGGAGAAGACCATCGCAGCAAAGCGTGCTGGAGTGACGTGCATCGTGCTGCCAGCCGAGAACA
AGAAGGACTTCTACGACCTGGCGGCCTTCATCACCGAGGGCCTGGAGGTCCACTTCGTGGAGCA
CTACCGCGAGATCTTCAGCATCGCCTTCCCCGAGGAGCCCGCGGAGGCCCTGGCCGTGGAGCGG
TGACGGCAGCCCGGGCTCCGCTGGCACGGGCGGCCCGGTGGGGCCACAGGGCGCCGGGCCGGAG
CTCTGGGCAGCTGCGCCGCCAGGAGGCTCAGGAGAGGCCCGCGCGCAAGGACTTGGCTTAATCA
CGGAGTCCGGCATAGATGAACTATTTAATGATGATTAAAACCCTTTCCAGTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038284885	(Get FASTA)	NCBI Sequence Viewer
	XP_038360519	(Get FASTA)	NCBI Sequence Viewer
	XP_038423564	(Get FASTA)	NCBI Sequence Viewer
	XP_038487718	(Get FASTA)	NCBI Sequence Viewer
	XP_854391	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000027714.6
	ENSCAFP00030036714.1
	ENSCAFP00845017958
	ENSCAFP00845017958.1
	ENSCAFP00845017988.1

RefSeq Acc Id:

XP_854391 ⟸ XM_849298

- UniProtKB:

A0A8P0SML3 (UniProtKB/TrEMBL), A0A8C0P8W2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAGTGYVRLWGAARCWALRRPLLAAAWGRVPTAAETWLPRGRRACDASPPWALWGRGPVAAGQ
WRGLWEANSRGGSGAFSSGEDASEGGAEDGSAGAGGSAGGGEGPIITALTPMTIPDVFPHLPLI
AVTRNPVFPRFIKIIEVKNKKLVELLRRKVRLAQPYAGVFLKRDDNNESDVVESLDEVYHTGTF
VQIHEMQDLGDKLRMIVMGHRRIHISRQLEVELEEAEAENKQKPRRKTKRGKKEVEEDLGAGHP
MEMVVEPASGSPGEVLMVEVENVVHEDFQVTEEVKALTAEIVKTIRDIIALNPLYRESVLQMMQ
AGQRVVDNPIYLSDMGAALTGAESHELQDVLEETNIPKRLYKALSLLKKEFELSKLQQRLGREV
EEKIKQTHRKYLLQEQLKIIKKELGLEKDDKDAIEEKFRERLKELVVPKHVMDVVDEELSKLGL
LDNHSSEFNVTRNYLDWLTSIPWGKYSNENLDLARAQAVLEEDHYGMEDVKKRILEFIAVSQLR
GSTQGKILCFYGPPGVGKTSIARSIARALNREYFRFSVGGMTDVAEIKGHRRTYVGAMPGKIIQ
CLKKTKTENPLILIDEVDKIGRGYQGDPSSALLELLDPEQNANFLDHYLDVPVDLSKVLFICTA
NVTETIPEPLRDRMEMINVSGYVAQEKLAIAERYLVPQARALCGLDESKAKLSSDVLTLLIKQY
CRESGVRNLQKQVEKVLRKSAYKIVSGEADLVEVTPENLQDFVGKPVFTVERMYDVTPPGVVMG
LAWTAMGGSTLFVETSPRRPRDKDSKGDKDGSLEVTGQLGDVMKESARIAYTFARAFLMQHDPT
NDYLVTSHIHLHVPEGATPKDGPSAGCTIVTALLSLAMDQPVRPNLAMTGEVSLTGKILPVGGI
KEKTIAAKRAGVTCIVLPAENKKDFYDLAAFITEGLEVHFVEHYREIFSIAFPEEPAEALAVER

hide sequence

RefSeq Acc Id:

ENSCAFP00000027714 ⟸ ENSCAFT00000029820

RefSeq Acc Id:

XP_038360519 ⟸ XM_038504591

RefSeq Acc Id:

XP_038487718 ⟸ XM_038631790

RefSeq Acc Id:	XP_038284885 ⟸ XM_038428957
- UniProtKB:	A0A8I3NN56 (UniProtKB/TrEMBL), A0A8C0P8W2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038423564 ⟸ XM_038567636
- UniProtKB:	A0A8C0L373 (UniProtKB/TrEMBL), A0A8C0P8W2 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845017958 ⟸ ENSCAFT00845022906

RefSeq Acc Id:

ENSCAFP00845017988 ⟸ ENSCAFT00845022947

Protein Domains

Lon N-terminal Lon proteolytic

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000018775	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030022779	UniProtKB/TrEMBL
	ENSCAFG00845012796	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000029820.6	UniProtKB/TrEMBL
	ENSCAFT00030042086.1	UniProtKB/TrEMBL
	ENSCAFT00845022906	ENTREZGENE
	ENSCAFT00845022906.1	UniProtKB/TrEMBL
	ENSCAFT00845022947.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.8.60	UniProtKB/TrEMBL
	1.20.5.5270	UniProtKB/TrEMBL
	1.20.58.1480	UniProtKB/TrEMBL
	2.30.130.40	UniProtKB/TrEMBL
	3.30.230.10	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
InterPro	AAA+_ATPase	UniProtKB/TrEMBL
	ATPase_AAA_core	UniProtKB/TrEMBL
	Lon_bac/euk-typ	UniProtKB/TrEMBL
	Lon_proteolytic	UniProtKB/TrEMBL
	Lon_Prtase	UniProtKB/TrEMBL
	Lon_prtase_N	UniProtKB/TrEMBL
	Lon_prtase_N_sf	UniProtKB/TrEMBL
	Lonm_euk	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	Peptidase_S16_AS	UniProtKB/TrEMBL
	PUA-like_sf	UniProtKB/TrEMBL
	Ribosomal_S5_D2-typ_fold	UniProtKB/TrEMBL
	Ribosomal_S5_D2-typ_fold_subgr	UniProtKB/TrEMBL
NCBI Gene	LONP1	ENTREZGENE
PANTHER	LON PROTEASE HOMOLOG, MITOCHONDRIAL	UniProtKB/TrEMBL
	PTHR43718	UniProtKB/TrEMBL
Pfam	AAA	UniProtKB/TrEMBL
	Lon_C	UniProtKB/TrEMBL
	LON_substr_bdg	UniProtKB/TrEMBL
PIRSF	Lon_proteas	UniProtKB/TrEMBL
PRINTS	ENDOLAPTASE	UniProtKB/TrEMBL
PROSITE	LON_N	UniProtKB/TrEMBL
	LON_PROTEOLYTIC	UniProtKB/TrEMBL
	LON_SER	UniProtKB/TrEMBL
SMART	AAA	UniProtKB/TrEMBL
	LON	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
	SSF54211	UniProtKB/TrEMBL
	SSF88697	UniProtKB/TrEMBL
UniProt	A0A8C0L373	ENTREZGENE
	A0A8C0P8W2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NK29_CANLF	UniProtKB/TrEMBL
	A0A8I3NN56	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0SML3	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:54321	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM