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Gene: Tubb4a (tubulin, beta 4A class IVa) Rattus norvegicus
Symbol: Tubb4a
Name: tubulin, beta 4A class IVa
RGD ID: 619730
Description: Predicted to have GTP binding activity and calcium ion binding activity. Predicted to be involved in microtubule cytoskeleton organization; mitotic cell cycle; and negative regulation of microtubule polymerization. Predicted to localize to several cellular components, including cytoskeleton; internode region of axon; and neuronal cell body. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 6 and torsion dystonia 4. Orthologous to human TUBB4A (tubulin beta 4A class IVa); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Tubb4; tubulin beta-4A chain; tubulin, beta 4; tubulin, beta 4 class IVa
Homo sapiens (human) : TUBB4A (tubulin beta 4A class IVa)  HGNC  Alliance
Mus musculus (house mouse) : Tubb4a (tubulin, beta 4A class IVA)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tubb4a (tubulin beta 4A class IVa)
Pan paniscus (bonobo/pygmy chimpanzee) : TUBB4A (tubulin beta 4A class IVa)
Canis lupus familiaris (dog) : TUBB4A (tubulin beta 4A class IVa)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tubb4a (tubulin beta 4A class IVa)
Sus scrofa (pig) : TUBB4A (tubulin beta 4A class IVa)
Heterocephalus glaber (naked mole-rat) : Tubb4a (tubulin beta 4A class IVa)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.099,961,020 - 9,968,420 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl99,961,021 - 9,968,486 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.098,960,772 - 8,968,172 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera96,592,438 - 6,599,882 (+)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Tubb4a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619730
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.