Tbc1d5 (TBC1 domain family, member 5) - Rat Genome Database

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Gene: Tbc1d5 (TBC1 domain family, member 5) Rattus norvegicus
Analyze
Symbol: Tbc1d5
Name: TBC1 domain family, member 5
RGD ID: 1561626
Description: Predicted to enable AP-2 adaptor complex binding activity; GTPase activator activity; and retromer complex binding activity. Predicted to be involved in several processes, including activation of GTPase activity; positive regulation of receptor internalization; and retrograde transport, endosome to Golgi. Predicted to be located in Golgi apparatus; autophagosome; and endosome membrane. Predicted to be part of retromer complex. Orthologous to human TBC1D5 (TBC1 domain family member 5); PARTICIPATES IN retromer-mediated pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,5-hexanedione; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC501088; RGD1561626; similar to TBC1 domain family, member 5; TBC1 domain family member 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.293,503,328 - 4,017,131 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl93,513,623 - 4,016,913 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx94,680,753 - 5,200,179 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.099,852,802 - 10,372,136 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.098,985,996 - 9,505,071 (-)NCBIRnor_WKY
Rnor_6.091,144,641 - 1,747,732 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl91,145,700 - 1,746,397 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.091,106,437 - 1,325,473 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.091,393,160 - 1,704,245 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.494,112,690 - 4,650,663 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera9417,936 - 917,218 (-)NCBICelera
Cytogenetic Map9q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Retromer and sorting nexins in endosomal sorting. Gallon M and Cullen PJ, Biochem Soc Trans. 2015 Feb;43(1):33-47. doi: 10.1042/BST20140290.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:17646400   PMID:19531583   PMID:20923837   PMID:22354992   PMID:24603492   PMID:25931508   PMID:27385586  


Genomics

Comparative Map Data
Tbc1d5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.293,503,328 - 4,017,131 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl93,513,623 - 4,016,913 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx94,680,753 - 5,200,179 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.099,852,802 - 10,372,136 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.098,985,996 - 9,505,071 (-)NCBIRnor_WKY
Rnor_6.091,144,641 - 1,747,732 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl91,145,700 - 1,746,397 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.091,106,437 - 1,325,473 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.091,393,160 - 1,704,245 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.494,112,690 - 4,650,663 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera9417,936 - 917,218 (-)NCBICelera
Cytogenetic Map9q11NCBI
TBC1D5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38317,157,162 - 17,742,631 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl317,157,162 - 18,444,817 (-)EnsemblGRCh38hg38GRCh38
GRCh37317,198,654 - 17,784,123 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36317,174,903 - 17,757,403 (-)NCBINCBI36Build 36hg18NCBI36
Build 34317,174,902 - 17,757,403NCBI
Celera317,137,647 - 17,722,084 (-)NCBICelera
Cytogenetic Map3p24.3NCBI
HuRef317,133,466 - 17,719,908 (-)NCBIHuRef
CHM1_1317,150,453 - 17,736,433 (-)NCBICHM1_1
T2T-CHM13v2.0317,159,342 - 17,744,665 (-)NCBIT2T-CHM13v2.0
Tbc1d5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391751,040,155 - 51,488,228 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1751,040,152 - 51,486,380 (-)EnsemblGRCm39 Ensembl
GRCm381750,733,124 - 51,181,199 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1750,733,124 - 51,179,352 (-)EnsemblGRCm38mm10GRCm38
MGSCv371750,872,452 - 51,318,674 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361750,198,695 - 50,644,264 (-)NCBIMGSCv36mm8
Celera1754,189,254 - 54,641,895 (-)NCBICelera
Cytogenetic Map17CNCBI
Tbc1d5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554309,410,475 - 9,940,460 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554309,411,865 - 9,966,710 (-)NCBIChiLan1.0ChiLan1.0
TBC1D5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1317,416,307 - 17,999,493 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl317,416,307 - 17,768,132 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0317,080,589 - 17,664,776 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TBC1D5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12325,206,825 - 25,758,026 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2325,254,448 - 25,757,385 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2325,200,607 - 25,733,279 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02325,705,164 - 26,258,261 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2325,705,188 - 26,258,001 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12325,413,938 - 25,960,236 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02325,475,448 - 26,020,155 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02325,726,585 - 26,269,437 (+)NCBIUU_Cfam_GSD_1.0
Tbc1d5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118176,730,088 - 177,155,898 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364739,868,430 - 10,188,484 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049364739,868,657 - 10,294,554 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBC1D5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl134,201,255 - 4,633,312 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1134,191,544 - 4,738,448 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2134,510,127 - 4,870,221 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TBC1D5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11562,009,952 - 62,569,187 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1562,006,701 - 62,358,449 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604134,998,278 - 35,563,925 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbc1d5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248212,398,042 - 2,806,263 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248212,398,211 - 3,068,212 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tbc1d5
2105 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:183
Count of miRNA genes:134
Interacting mature miRNAs:165
Transcripts:ENSRNOT00000014171
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9114209783Rat
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
631533Iresp3Immunoglobin response QTL316.2blood immunoglobulin E amount (VT:0002492)serum total immunoglobulin E level (CMO:0001542)927457995857951Rat
1578675Bss17Bone structure and strength QTL 173.8femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)9336865213533896Rat

Markers in Region
D9Got4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.293,557,266 - 3,557,403 (-)MAPPERmRatBN7.2
Rnor_6.091,702,768 - 1,702,904NCBIRnor6.0
Rnor_5.091,660,616 - 1,660,752UniSTSRnor5.0
RGSC_v3.494,606,822 - 4,606,959RGDRGSC3.4
RGSC_v3.494,606,823 - 4,606,959UniSTSRGSC3.4
RGSC_v3.194,606,822 - 4,606,959RGD
Celera9461,040 - 461,176UniSTS
Cytogenetic Map9q11UniSTS
RH139882  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.293,673,796 - 3,674,013 (-)MAPPERmRatBN7.2
Rnor_6.091,547,647 - 1,547,863NCBIRnor6.0
Rnor_5.091,507,302 - 1,507,518UniSTSRnor5.0
RGSC_v3.494,485,475 - 4,485,691UniSTSRGSC3.4
Celera9576,510 - 576,726UniSTS
Cytogenetic Map9q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 25 25 9 19 9 1 1 74 35 41 11 1
Low 18 32 32 32 7 10 7
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001134762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005488952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC162056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000014171   ⟹   ENSRNOP00000014171
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl93,513,623 - 4,016,913 (-)Ensembl
Rnor_6.0 Ensembl91,145,700 - 1,746,397 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000083387   ⟹   ENSRNOP00000074017
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl93,513,623 - 4,016,913 (-)Ensembl
Rnor_6.0 Ensembl91,313,209 - 1,745,262 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112471   ⟹   ENSRNOP00000094871
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl93,513,623 - 4,016,913 (-)Ensembl
RefSeq Acc Id: NM_001134762   ⟹   NP_001128234
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.293,513,623 - 4,016,913 (-)NCBI
Rnor_6.091,145,700 - 1,746,397 (+)NCBI
Rnor_5.091,106,437 - 1,325,473 (+)NCBI
Rnor_5.091,393,160 - 1,704,245 (+)NCBI
RGSC_v3.494,112,690 - 4,650,663 (+)RGD
Celera9417,936 - 917,218 (-)RGD
Sequence:
RefSeq Acc Id: XM_008766768   ⟹   XP_008764990
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.293,512,288 - 4,017,126 (-)NCBI
Rnor_6.091,144,641 - 1,745,577 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017596593   ⟹   XP_017452082
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.293,512,288 - 4,017,126 (-)NCBI
Rnor_6.091,144,641 - 1,747,732 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017596594   ⟹   XP_017452083
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.293,512,288 - 4,017,126 (-)NCBI
Rnor_6.091,144,641 - 1,745,577 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039084050   ⟹   XP_038939978
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.293,512,288 - 4,017,126 (-)NCBI
RefSeq Acc Id: XM_039084051   ⟹   XP_038939979
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.293,512,288 - 3,979,986 (-)NCBI
RefSeq Acc Id: XM_039084052   ⟹   XP_038939980
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.293,512,288 - 4,017,130 (-)NCBI
RefSeq Acc Id: XM_039084053   ⟹   XP_038939981
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.293,512,288 - 4,017,130 (-)NCBI
RefSeq Acc Id: XM_039084054   ⟹   XP_038939982
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.293,512,288 - 4,017,128 (-)NCBI
RefSeq Acc Id: XM_039084056   ⟹   XP_038939984
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.293,512,288 - 4,017,131 (-)NCBI
RefSeq Acc Id: XM_039084057   ⟹   XP_038939985
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.293,512,288 - 3,777,795 (-)NCBI
RefSeq Acc Id: XM_039084058   ⟹   XP_038939986
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.293,674,429 - 4,017,124 (-)NCBI
RefSeq Acc Id: XR_005488952
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.293,503,328 - 4,017,126 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001128234   ⟸   NM_001134762
- UniProtKB: F1M9Q1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008764990   ⟸   XM_008766768
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K712 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452082   ⟸   XM_017596593
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K712 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452083   ⟸   XM_017596594
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K712 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000014171   ⟸   ENSRNOT00000014171
RefSeq Acc Id: ENSRNOP00000074017   ⟸   ENSRNOT00000083387
RefSeq Acc Id: XP_038939984   ⟸   XM_039084056
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038939980   ⟸   XM_039084052
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038939981   ⟸   XM_039084053
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038939982   ⟸   XM_039084054
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038939978   ⟸   XM_039084050
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K712 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939979   ⟸   XM_039084051
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K712 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939985   ⟸   XM_039084057
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038939986   ⟸   XM_039084058
- Peptide Label: isoform X6
RefSeq Acc Id: ENSRNOP00000094871   ⟸   ENSRNOT00000112471
Protein Domains
Rab-GAP TBC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K712-F1-model_v2 AlphaFold A0A0G2K712 1-827 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696418
Promoter ID:EPDNEW_R6943
Type:initiation region
Name:Tbc1d5_1
Description:TBC1 domain family, member 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.091,145,690 - 1,145,750EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561626 AgrOrtholog
BioCyc Gene G2FUF-28430 BioCyc
Ensembl Genes ENSRNOG00000010637 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000014171 ENTREZGENE
  ENSRNOP00000014171.5 UniProtKB/TrEMBL
  ENSRNOP00000074017 ENTREZGENE
  ENSRNOP00000074017.1 UniProtKB/TrEMBL
  ENSRNOP00000094871.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014171 ENTREZGENE
  ENSRNOT00000014171.7 UniProtKB/TrEMBL
  ENSRNOT00000083387 ENTREZGENE
  ENSRNOT00000083387.2 UniProtKB/TrEMBL
  ENSRNOT00000112471.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7114456 IMAGE-MGC_LOAD
InterPro Rab-GTPase_TBC_sf UniProtKB/TrEMBL
  RabGAP/TBC_dom UniProtKB/TrEMBL
KEGG Report rno:501088 UniProtKB/TrEMBL
MGC_CLONE MGC:188045 IMAGE-MGC_LOAD
NCBI Gene 501088 ENTREZGENE
Pfam RabGAP-TBC UniProtKB/TrEMBL
PhenoGen Tbc1d5 PhenoGen
PROSITE TBC_RABGAP UniProtKB/TrEMBL
SMART TBC UniProtKB/TrEMBL
Superfamily-SCOP RabGAP_TBC UniProtKB/TrEMBL
UniProt A0A0G2K712 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AMF2_RAT UniProtKB/TrEMBL
  B1WC98_RAT UniProtKB/TrEMBL
  F1M9Q1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-29 Tbc1d5  TBC1 domain family, member 5  RGD1561626_predicted  similar to TBC1 domain family, member 5 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1561626_predicted  similar to TBC1 domain family, member 5 (predicted)  LOC501088  similar to TBC1 domain family, member 5  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC501088  similar to TBC1 domain family, member 5      Symbol and Name status set to provisional 70820 PROVISIONAL