Symbol:
Ccnd3
Name:
cyclin D3
RGD ID:
2293
Description:
Enables protein kinase binding activity. Involved in several processes, including G1/S transition of mitotic cell cycle; hyaluronan biosynthetic process; and response to glucose. Predicted to be located in nucleoplasm. Predicted to be part of cyclin D3-CDK4 complex and cyclin D3-CDK6 complex. Predicted to be active in cytoplasm; microtubule organizing center; and nucleus. Orthologous to human CCND3 (cyclin D3); PARTICIPATES IN G1/S transition pathway; cell cycle pathway, mitotic; Jak-Stat signaling pathway; INTERACTS WITH 17beta-estradiol; 2-methoxyethanol; 3,3',5,5'-tetrabromobisphenol A.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
G1/S-specific cyclin-D3; MGC108760; MGC93643
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
CCND3 (cyclin D3) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):
Ccnd3 (cyclin D3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Ccnd3 (cyclin D3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
CCND3 (cyclin D3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
CCND3 (cyclin D3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Ccnd3 (cyclin D3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
CCND3 (cyclin D3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
CCND3 (cyclin D3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Ccnd3 (cyclin D3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
TSEN34 (tRNA splicing endonuclease subunit 34) HGNC
OMA
Alliance orthologs 3
Mus musculus (house mouse):
Ccnd3 (cyclin D3)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
CCND3 (cyclin D3)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
ccnd3 (cyclin D3)
Alliance
DIOPT (OrthoFinder|PANTHER|PhylomeDB)
Drosophila melanogaster (fruit fly):
CycD
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
cyd-1
Alliance
DIOPT (Ensembl Compara|InParanoid|OrthoFinder|OrthoInspector|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):
CLN3
Alliance
DIOPT (Ensembl Compara|PANTHER)
Saccharomyces cerevisiae (baker's yeast):
CLN2
Alliance
DIOPT (Ensembl Compara|PANTHER)
Saccharomyces cerevisiae (baker's yeast):
CLN1
Alliance
DIOPT (Ensembl Compara|PANTHER)
Xenopus tropicalis (tropical clawed frog):
ccndx
Alliance
DIOPT (Ensembl Compara|InParanoid|OMA)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 9 20,891,696 - 20,987,199 (-) NCBI GRCr8 mRatBN7.2 9 13,394,161 - 13,400,341 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 9 13,394,169 - 13,489,371 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 9 21,973,914 - 21,980,097 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 9 27,038,080 - 27,044,259 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 9 25,337,315 - 25,343,498 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 9 15,404,816 - 15,410,905 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 9 15,404,822 - 15,410,943 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 9 14,326,227 - 14,332,267 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 Celera 9 11,145,441 - 11,151,481 (-) NCBI Celera Cytogenetic Map 9 q12 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Ccnd3 Rat (aminomethyl)phosphonic acid multiple interactions ISO CCND3 (Homo sapiens) 6480464 [1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in decreased expression of CCND3 protein CTD PMID:26006246 Ccnd3 Rat (aminomethyl)phosphonic acid decreases expression ISO CCND3 (Homo sapiens) 6480464 1-aminomethylphosphonic acid results in decreased expression of CCND3 protein CTD PMID:23983455 Ccnd3 Rat (S)-amphetamine increases expression ISO Ccnd3 (Mus musculus) 6480464 Dextroamphetamine results in increased expression of CCND3 mRNA CTD PMID:12558987 Ccnd3 Rat 1,2-dimethylhydrazine multiple interactions ISO Ccnd3 (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of CCND3 mRNA] CTD PMID:22206623 Ccnd3 Rat 1,2-dimethylhydrazine increases expression ISO Ccnd3 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of CCND3 mRNA CTD PMID:22206623 Ccnd3 Rat 14-Deoxy-11,12-didehydroandrographolide decreases expression ISO CCND3 (Homo sapiens) 6480464 14-deoxy-11 and 12-didehydroandrographolide results in decreased expression of CCND3 mRNA CTD PMID:22101062 Ccnd3 Rat 15-deoxy-Delta(12,14)-prostaglandin J2 decreases expression ISO CCND3 (Homo sapiens) 6480464 15-deoxy-delta(12 and 14)-prostaglandin J2 results in decreased expression of CCND3 protein CTD PMID:15729575 Ccnd3 Rat 17alpha-ethynylestradiol affects expression ISO Ccnd3 (Mus musculus) 6480464 Ethinyl Estradiol affects the expression of CCND3 mRNA CTD PMID:17555576 Ccnd3 Rat 17alpha-ethynylestradiol multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CCND3 mRNA CTD PMID:17942748 Ccnd3 Rat 17alpha-ethynylestradiol increases expression ISO Ccnd3 (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of CCND3 mRNA CTD PMID:17942748 Ccnd3 Rat 17beta-estradiol multiple interactions ISO Ccnd3 (Mus musculus) 6480464 Cycloheximide affects the reaction [Estradiol affects the expression of CCND3 mRNA] more ... CTD PMID:9094091 Ccnd3 Rat 17beta-estradiol multiple interactions ISO CCND3 (Homo sapiens) 6480464 IGF1R mutant form promotes the reaction [Estradiol results in increased expression of CCND3 mRNA] CTD PMID:23094148 Ccnd3 Rat 17beta-estradiol increases expression ISO CCND3 (Homo sapiens) 6480464 Estradiol results in increased expression of CCND3 mRNA CTD PMID:15897899 more ... Ccnd3 Rat 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of CCND3 mRNA CTD PMID:24236210 Ccnd3 Rat 17beta-estradiol affects expression ISO CCND3 (Homo sapiens) 6480464 Estradiol affects the expression of CCND3 mRNA CTD PMID:21826169 and PMID:22574217 Ccnd3 Rat 17beta-estradiol increases expression ISO Ccnd3 (Mus musculus) 6480464 Estradiol results in increased expression of CCND3 mRNA CTD PMID:11861973 Ccnd3 Rat 17beta-estradiol affects expression ISO Ccnd3 (Mus musculus) 6480464 Estradiol affects the expression of CCND3 mRNA CTD PMID:9094091 Ccnd3 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CCND3 mRNA CTD PMID:17942748 Ccnd3 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ccnd3 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of CCND3 mRNA CTD PMID:18343893 more ... Ccnd3 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Ccnd3 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of CCND3 mRNA CTD PMID:21041162 Ccnd3 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Ccnd3 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of CCND3 mRNA CTD PMID:15328365 and PMID:17942748 Ccnd3 Rat 2,3,7,8-Tetrachlorodibenzofuran affects expression ISO Ccnd3 (Mus musculus) 6480464 2 more ... CTD PMID:18343893 Ccnd3 Rat 2-methoxy-17beta-estradiol decreases expression ISO CCND3 (Homo sapiens) 6480464 2-Methoxyestradiol results in decreased expression of CCND3 protein CTD PMID:23967052 Ccnd3 Rat 2-methoxyethanol affects expression EXP 6480464 methyl cellosolve affects the expression of CCND3 mRNA CTD PMID:19643169 Ccnd3 Rat 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of CCND3 mRNA CTD PMID:26988606 Ccnd3 Rat 3,3'-diindolylmethane decreases expression ISO CCND3 (Homo sapiens) 6480464 3 and 3'-diindolylmethane results in decreased expression of CCND3 protein CTD PMID:22514694 Ccnd3 Rat 4,4'-diaminodiphenylmethane decreases expression ISO Ccnd3 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of CCND3 mRNA CTD PMID:18648102 Ccnd3 Rat 4,4'-sulfonyldiphenol decreases expression ISO Ccnd3 (Mus musculus) 6480464 bisphenol S results in decreased expression of CCND3 mRNA CTD PMID:39298647 Ccnd3 Rat 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of CCND3 mRNA CTD PMID:36041667 Ccnd3 Rat 4,4'-sulfonyldiphenol decreases methylation ISO Ccnd3 (Mus musculus) 6480464 bisphenol S results in decreased methylation of CCND3 exon CTD PMID:33297965 Ccnd3 Rat 4-hydroxynon-2-enal multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of CCND3 protein and sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of CCND3 protein] CTD PMID:33007382 Ccnd3 Rat 5-fluorouracil affects response to substance ISO CCND3 (Homo sapiens) 6480464 CCND3 affects the susceptibility to Fluorouracil and CCND3 protein affects the susceptibility to Fluorouracil CTD PMID:15067352 more ... Ccnd3 Rat 5-fluorouracil increases expression ISO CCND3 (Homo sapiens) 6480464 Fluorouracil results in increased expression of CCND3 mRNA CTD PMID:16709241 Ccnd3 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of CCND3 mRNA CTD PMID:30047161 Ccnd3 Rat 9-cis-retinoic acid decreases expression ISO CCND3 (Homo sapiens) 6480464 Alitretinoin results in decreased expression of CCND3 protein CTD PMID:16273314 Ccnd3 Rat acetylleucyl-leucyl-norleucinal multiple interactions ISO CCND3 (Homo sapiens) 6480464 acetylleucyl-leucyl-norleucinal inhibits the reaction [Tretinoin results in increased degradation of and results in decreased expression of CCND3 protein] CTD PMID:16024653 Ccnd3 Rat acetylsalicylic acid multiple interactions ISO CCND3 (Homo sapiens) 6480464 Aspirin promotes the reaction [troglitazone results in decreased expression of CCND3 protein] and troglitazone promotes the reaction [Aspirin results in decreased expression of CCND3 protein] CTD PMID:19908241 Ccnd3 Rat acetylsalicylic acid decreases expression ISO CCND3 (Homo sapiens) 6480464 Aspirin results in decreased expression of CCND3 mRNA and Aspirin results in decreased expression of CCND3 protein CTD PMID:14976132 and PMID:19908241 Ccnd3 Rat acteoside decreases expression ISO CCND3 (Homo sapiens) 6480464 acteoside results in decreased expression of CCND3 protein CTD PMID:17634406 Ccnd3 Rat aflatoxin B1 increases expression ISO CCND3 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of CCND3 mRNA CTD PMID:22100608 Ccnd3 Rat aflatoxin B1 increases methylation ISO CCND3 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of CCND3 gene and Aflatoxin B1 results in increased methylation of CCND3 promoter CTD PMID:27153756 and PMID:30157460 Ccnd3 Rat alendronic acid decreases expression ISO CCND3 (Homo sapiens) 6480464 Alendronate results in decreased expression of CCND3 protein CTD PMID:39137827 Ccnd3 Rat all-trans-retinoic acid multiple interactions ISO CCND3 (Homo sapiens) 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Tretinoin promotes the reaction [CPG-oligonucleotide results in increased expression of CCND3 protein]] more ... CTD PMID:12421932 more ... Ccnd3 Rat all-trans-retinoic acid increases expression ISO CCND3 (Homo sapiens) 6480464 Tretinoin results in increased expression of CCND3 mRNA and Tretinoin results in increased expression of CCND3 protein CTD PMID:16920920 and PMID:20507312 Ccnd3 Rat all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of CCND3 protein CTD PMID:11675954 Ccnd3 Rat all-trans-retinoic acid multiple interactions EXP 6480464 Tretinoin inhibits the reaction [FGF2 protein results in increased expression of CCND3 mRNA] CTD PMID:11675954 Ccnd3 Rat all-trans-retinoic acid decreases expression ISO Ccnd3 (Mus musculus) 6480464 Tretinoin results in decreased expression of CCND3 mRNA CTD PMID:16604517 Ccnd3 Rat all-trans-retinoic acid decreases expression ISO CCND3 (Homo sapiens) 6480464 Tretinoin results in decreased expression of CCND3 mRNA CTD PMID:16024653 Ccnd3 Rat Allylamine increases expression EXP 6480464 Allylamine results in increased expression of CCND3 mRNA CTD PMID:15910882 Ccnd3 Rat amitrole increases expression EXP 6480464 Amitrole results in increased expression of CCND3 mRNA CTD PMID:30047161 Ccnd3 Rat ammonium chloride increases expression EXP 6480464 Ammonium Chloride results in increased expression of CCND3 protein CTD PMID:16483693 Ccnd3 Rat aniline increases expression EXP 6480464 aniline results in increased expression of CCND3 mRNA and aniline results in increased expression of CCND3 protein CTD PMID:21070798 and PMID:28463034 Ccnd3 Rat aristolochic acid A increases expression ISO CCND3 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of CCND3 mRNA and aristolochic acid I results in increased expression of CCND3 protein CTD PMID:33212167 Ccnd3 Rat arotinoid acid multiple interactions ISO CCND3 (Homo sapiens) 6480464 4-(2-(5 more ... CTD PMID:12421932 Ccnd3 Rat arotinoid acid decreases expression ISO CCND3 (Homo sapiens) 6480464 4-(2-(5 more ... CTD PMID:16273314 Ccnd3 Rat arsane multiple interactions ISO CCND3 (Homo sapiens) 6480464 [silybin co-treated with Arsenic] results in decreased expression of CCND3 protein CTD PMID:25868784 Ccnd3 Rat arsenic atom multiple interactions ISO CCND3 (Homo sapiens) 6480464 [silybin co-treated with Arsenic] results in decreased expression of CCND3 protein CTD PMID:25868784 Ccnd3 Rat arsenite(3-) multiple interactions ISO CCND3 (Homo sapiens) 6480464 arsenite promotes the reaction [G3BP1 protein binds to CCND3 mRNA] CTD PMID:32406909 Ccnd3 Rat arsenous acid increases expression ISO CCND3 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of CCND3 mRNA CTD PMID:29633893 Ccnd3 Rat arsenous acid decreases expression ISO CCND3 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of CCND3 mRNA CTD PMID:20458559 Ccnd3 Rat atrazine decreases expression ISO CCND3 (Homo sapiens) 6480464 Atrazine results in decreased expression of CCND3 mRNA CTD PMID:22378314 Ccnd3 Rat atropine multiple interactions ISO CCND3 (Homo sapiens) 6480464 [Parathion co-treated with Atropine] results in increased expression of CCND3 mRNA CTD PMID:17390078 Ccnd3 Rat benzene multiple interactions ISO Ccnd3 (Mus musculus) 6480464 TRP53 protein promotes the reaction [Benzene results in decreased expression of CCND3] CTD PMID:15935813 Ccnd3 Rat benzo[a]pyrene increases expression ISO CCND3 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of CCND3 mRNA CTD PMID:21632981 and PMID:33411230 Ccnd3 Rat benzo[a]pyrene affects methylation ISO CCND3 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of CCND3 5' UTR and Benzo(a)pyrene affects the methylation of CCND3 promoter CTD PMID:27901495 and PMID:30157460 Ccnd3 Rat benzo[a]pyrene increases methylation ISO CCND3 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of CCND3 3' UTR CTD PMID:27901495 Ccnd3 Rat benzo[a]pyrene decreases methylation ISO CCND3 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of CCND3 promoter CTD PMID:27901495 Ccnd3 Rat benzo[a]pyrene decreases methylation ISO Ccnd3 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased methylation of CCND3 intron CTD PMID:27901495 Ccnd3 Rat benzo[b]fluoranthene increases expression ISO Ccnd3 (Mus musculus) 6480464 benzo(b)fluoranthene results in increased expression of CCND3 mRNA CTD PMID:26377693 Ccnd3 Rat benzoates decreases expression ISO CCND3 (Homo sapiens) 6480464 Benzoates analog results in decreased expression of CCND3 mRNA CTD PMID:29472718 Ccnd3 Rat beta-lapachone decreases expression ISO CCND3 (Homo sapiens) 6480464 beta-lapachone results in decreased expression of CCND3 mRNA CTD PMID:38218311 Ccnd3 Rat biotin increases expression ISO Ccnd3 (Mus musculus) 6480464 Biotin results in increased expression of CCND3 mRNA CTD PMID:34699867 Ccnd3 Rat biphenyl-4-amine multiple interactions ISO CCND3 (Homo sapiens) 6480464 TP53 protein inhibits the reaction [4-biphenylamine results in decreased expression of CCND3 mRNA] CTD PMID:32905825 Ccnd3 Rat biphenyl-4-amine decreases expression ISO CCND3 (Homo sapiens) 6480464 4-biphenylamine results in decreased expression of CCND3 mRNA CTD PMID:32905825 Ccnd3 Rat bis(2-ethylhexyl) phthalate increases expression ISO CCND3 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of CCND3 mRNA CTD PMID:31163220 Ccnd3 Rat bis(2-ethylhexyl) phthalate increases expression ISO Ccnd3 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of CCND3 mRNA CTD PMID:33754040 Ccnd3 Rat bisphenol A affects expression ISO CCND3 (Homo sapiens) 6480464 bisphenol A affects the expression of CCND3 mRNA CTD PMID:21826169 Ccnd3 Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of CCND3 mRNA CTD PMID:36041667 Ccnd3 Rat bisphenol A increases expression ISO Ccnd3 (Mus musculus) 6480464 bisphenol A results in increased expression of CCND3 mRNA CTD PMID:33221593 Ccnd3 Rat bisphenol A multiple interactions ISO CCND3 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of CCND3 gene and Curcumin inhibits the reaction [bisphenol A results in increased expression of CCND3 protein] CTD PMID:23222814 and PMID:31601247 Ccnd3 Rat bisphenol A increases expression ISO CCND3 (Homo sapiens) 6480464 bisphenol A results in increased expression of CCND3 protein CTD PMID:23222814 Ccnd3 Rat bisphenol F multiple interactions ISO CCND3 (Homo sapiens) 6480464 [bisphenol F co-treated with Fulvestrant] results in increased methylation of CCND3 gene CTD PMID:31601247 Ccnd3 Rat bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of CCND3 mRNA CTD PMID:36041667 Ccnd3 Rat bosutinib affects localization ISO Ccnd3 (Mus musculus) 6480464 bosutinib affects the localization of CCND3 protein CTD PMID:17129604 Ccnd3 Rat bosutinib multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [bosutinib co-treated with Imatinib Mesylate] affects the localization of CCND3 protein CTD PMID:17129604 Ccnd3 Rat bucladesine increases expression EXP 6480464 Bucladesine results in increased expression of CCND3 protein CTD PMID:16718685 Ccnd3 Rat butan-1-ol multiple interactions ISO CCND3 (Homo sapiens) 6480464 1-Butanol inhibits the reaction [PDGFB protein results in decreased expression of CCND3 protein] CTD PMID:15919668 Ccnd3 Rat Butylparaben affects expression ISO CCND3 (Homo sapiens) 6480464 butylparaben affects the expression of CCND3 mRNA CTD PMID:24481588 Ccnd3 Rat Butylparaben decreases expression ISO CCND3 (Homo sapiens) 6480464 butylparaben results in decreased expression of CCND3 mRNA CTD PMID:24481588 Ccnd3 Rat butyric acid increases expression EXP 6480464 Butyric Acid results in increased expression of CCND3 mRNA CTD PMID:12800193 Ccnd3 Rat cadmium atom multiple interactions EXP 6480464 fulvestrant inhibits the reaction [Cadmium results in increased expression of CCND3 mRNA] CTD PMID:24236210 Ccnd3 Rat cadmium atom multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CCND3 mRNA CTD PMID:37325564 Ccnd3 Rat cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of CCND3 mRNA CTD PMID:24236210 Ccnd3 Rat cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of CCND3 mRNA CTD PMID:18636176 Ccnd3 Rat cadmium dichloride multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CCND3 mRNA CTD PMID:37325564 Ccnd3 Rat cadmium dichloride increases expression ISO CCND3 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of CCND3 mRNA CTD PMID:32512071 Ccnd3 Rat cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of CCND3 mRNA CTD PMID:24236210 Ccnd3 Rat cadmium dichloride multiple interactions EXP 6480464 fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of CCND3 mRNA] CTD PMID:24236210 Ccnd3 Rat calycosin decreases expression ISO CCND3 (Homo sapiens) 6480464 7 and 3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of CCND3 mRNA CTD PMID:24455688 Ccnd3 Rat camostat multiple interactions ISO Ccnd3 (Mus musculus) 6480464 mirdametinib inhibits the reaction [camostat results in increased expression of CCND3 protein] CTD PMID:25104499 Ccnd3 Rat camostat increases expression ISO Ccnd3 (Mus musculus) 6480464 camostat results in increased expression of CCND3 protein CTD PMID:25104499 Ccnd3 Rat cannabidiol decreases expression ISO CCND3 (Homo sapiens) 6480464 Cannabidiol results in decreased expression of CCND3 mRNA and Cannabidiol results in decreased expression of CCND3 protein CTD PMID:34871667 and PMID:36519830 Ccnd3 Rat cannabidiol decreases expression ISO Ccnd3 (Mus musculus) 6480464 Cannabidiol results in decreased expression of CCND3 protein CTD PMID:34871667 Ccnd3 Rat carbamazepine affects expression ISO CCND3 (Homo sapiens) 6480464 Carbamazepine affects the expression of CCND3 mRNA CTD PMID:24752500 Ccnd3 Rat carbon nanotube decreases expression ISO CCND3 (Homo sapiens) 6480464 Nanotubes and Carbon results in decreased expression of CCND3 mRNA CTD PMID:15585362 Ccnd3 Rat carbon nanotube increases expression ISO Ccnd3 (Mus musculus) 6480464 Nanotubes and Carbon analog results in increased expression of CCND3 mRNA CTD PMID:25554681 Ccnd3 Rat CGP 52608 multiple interactions ISO CCND3 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to CCND3 gene] CTD PMID:28238834 Ccnd3 Rat chlorohydrocarbon decreases expression ISO CCND3 (Homo sapiens) 6480464 Hydrocarbons and Chlorinated results in decreased expression of CCND3 protein CTD PMID:14757120 Ccnd3 Rat chloroprene increases expression ISO Ccnd3 (Mus musculus) 6480464 Chloroprene results in increased expression of CCND3 mRNA CTD PMID:23125180 Ccnd3 Rat chlorpromazine decreases expression ISO CCND3 (Homo sapiens) 6480464 Chlorpromazine analog results in decreased expression of CCND3 mRNA CTD PMID:15924885 Ccnd3 Rat chromium(6+) decreases expression EXP 6480464 chromium hexavalent ion results in decreased expression of CCND3 protein CTD PMID:21621607 Ccnd3 Rat chromium(6+) multiple interactions EXP 6480464 Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCND3 protein] CTD PMID:21621607 Ccnd3 Rat cisplatin multiple interactions ISO CCND3 (Homo sapiens) 6480464 [Cisplatin co-treated with Quercetin] results in increased expression of CCND3 mRNA CTD PMID:27514524 Ccnd3 Rat cisplatin increases expression ISO CCND3 (Homo sapiens) 6480464 Cisplatin results in increased expression of CCND3 mRNA CTD PMID:27392435 and PMID:27594783 Ccnd3 Rat cisplatin increases expression ISO Ccnd3 (Mus musculus) 6480464 Cisplatin results in increased expression of CCND3 mRNA CTD PMID:21151649 Ccnd3 Rat clofibrate multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CCND3 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CCND3 mRNA] CTD PMID:17585979 Ccnd3 Rat clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of CCND3 mRNA CTD PMID:12851107 Ccnd3 Rat clozapine increases expression EXP 6480464 Clozapine results in increased expression of CCND3 mRNA CTD PMID:15860345 Ccnd3 Rat cobalt dichloride decreases expression ISO CCND3 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of CCND3 mRNA CTD PMID:19376846 Ccnd3 Rat cocaine affects expression EXP 6480464 Cocaine affects the expression of CCND3 mRNA CTD PMID:20187946 Ccnd3 Rat copper atom multiple interactions ISO CCND3 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in decreased expression of CCND3 mRNA and [Thiosemicarbazones binds to Copper] which results in decreased expression of CCND3 protein CTD PMID:20931265 and PMID:30911355 Ccnd3 Rat copper(0) multiple interactions ISO CCND3 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in decreased expression of CCND3 mRNA and [Thiosemicarbazones binds to Copper] which results in decreased expression of CCND3 protein CTD PMID:20931265 and PMID:30911355 Ccnd3 Rat curcumin multiple interactions ISO CCND3 (Homo sapiens) 6480464 Curcumin inhibits the reaction [bisphenol A results in increased expression of CCND3 protein] CTD PMID:23222814 Ccnd3 Rat curcumin decreases expression ISO CCND3 (Homo sapiens) 6480464 Curcumin results in decreased expression of CCND3 protein CTD PMID:23222814 Ccnd3 Rat cycloheximide affects expression ISO Ccnd3 (Mus musculus) 6480464 Cycloheximide affects the expression of CCND3 mRNA CTD PMID:9094091 Ccnd3 Rat cycloheximide multiple interactions ISO Ccnd3 (Mus musculus) 6480464 Cycloheximide affects the reaction [Estradiol affects the expression of CCND3 mRNA] CTD PMID:9094091 Ccnd3 Rat cyclophosphamide decreases expression ISO Ccnd3 (Mus musculus) 6480464 Cyclophosphamide results in decreased expression of CCND3 mRNA CTD PMID:21041162 Ccnd3 Rat cyclosporin A decreases expression ISO CCND3 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of CCND3 mRNA CTD PMID:25562108 Ccnd3 Rat cypermethrin decreases expression ISO Ccnd3 (Mus musculus) 6480464 cypermethrin results in decreased expression of CCND3 mRNA CTD PMID:36116546 Ccnd3 Rat cytarabine decreases expression ISO CCND3 (Homo sapiens) 6480464 Cytarabine results in decreased expression of CCND3 mRNA CTD PMID:21198554 Ccnd3 Rat daunorubicin increases expression ISO CCND3 (Homo sapiens) 6480464 Daunorubicin results in increased expression of CCND3 mRNA CTD PMID:12656675 Ccnd3 Rat deguelin decreases expression ISO CCND3 (Homo sapiens) 6480464 deguelin results in decreased expression of CCND3 mRNA CTD PMID:33512557 Ccnd3 Rat desferrioxamine B decreases expression ISO CCND3 (Homo sapiens) 6480464 Deferoxamine results in decreased expression of CCND3 protein CTD PMID:11468187 Ccnd3 Rat dexamethasone decreases expression ISO Ccnd3 (Mus musculus) 6480464 Dexamethasone results in decreased expression of CCND3 mRNA CTD PMID:21041162 Ccnd3 Rat diarsenic trioxide increases expression ISO CCND3 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of CCND3 mRNA CTD PMID:29633893 Ccnd3 Rat diarsenic trioxide decreases expression ISO CCND3 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of CCND3 mRNA CTD PMID:20458559 Ccnd3 Rat Dibutyl phosphate affects expression ISO CCND3 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of CCND3 mRNA CTD PMID:37042841 Ccnd3 Rat dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of CCND3 mRNA CTD PMID:21266533 Ccnd3 Rat dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of CCND3 mRNA CTD PMID:18636392 Ccnd3 Rat diclofenac affects expression ISO CCND3 (Homo sapiens) 6480464 Diclofenac affects the expression of CCND3 mRNA CTD PMID:24752500 Ccnd3 Rat diethylstilbestrol decreases expression ISO Ccnd3 (Mus musculus) 6480464 Diethylstilbestrol results in decreased expression of CCND3 mRNA CTD PMID:21041162 Ccnd3 Rat diuron affects expression ISO CCND3 (Homo sapiens) 6480464 Diuron affects the expression of CCND3 mRNA CTD PMID:35967413 Ccnd3 Rat dorsomorphin multiple interactions ISO CCND3 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCND3 mRNA CTD PMID:27188386 Ccnd3 Rat doxorubicin multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCND3 protein CTD PMID:19789217 Ccnd3 Rat doxorubicin increases expression ISO Ccnd3 (Mus musculus) 6480464 Doxorubicin results in increased expression of CCND3 mRNA CTD PMID:25896364 Ccnd3 Rat dronedarone decreases expression ISO CCND3 (Homo sapiens) 6480464 dronedarone results in decreased expression of CCND3 protein CTD PMID:29616291 Ccnd3 Rat ethyl methanesulfonate increases expression ISO CCND3 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of CCND3 mRNA CTD PMID:23649840 Ccnd3 Rat everolimus decreases expression ISO CCND3 (Homo sapiens) 6480464 Everolimus results in decreased expression of CCND3 protein CTD PMID:16856892 Ccnd3 Rat fenamidone increases expression ISO Ccnd3 (Mus musculus) 6480464 fenamidone results in increased expression of CCND3 mRNA CTD PMID:27029645 Ccnd3 Rat fluoxetine decreases expression ISO Ccnd3 (Mus musculus) 6480464 Fluoxetine results in decreased expression of CCND3 mRNA CTD PMID:21497159 Ccnd3 Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of CCND3 mRNA CTD PMID:19299419 Ccnd3 Rat folic acid decreases expression ISO CCND3 (Homo sapiens) 6480464 Folic Acid results in decreased expression of CCND3 mRNA CTD PMID:11723236 Ccnd3 Rat folic acid decreases expression ISO Ccnd3 (Mus musculus) 6480464 Folic Acid results in decreased expression of CCND3 mRNA CTD PMID:25629700 Ccnd3 Rat folic acid multiple interactions ISO Ccnd3 (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of CCND3 mRNA] CTD PMID:22206623 Ccnd3 Rat formaldehyde increases expression ISO CCND3 (Homo sapiens) 6480464 Formaldehyde results in increased expression of CCND3 mRNA CTD PMID:23649840 Ccnd3 Rat fulvestrant multiple interactions ISO Ccnd3 (Mus musculus) 6480464 fulvestrant inhibits the reaction [Estradiol affects the expression of CCND3 mRNA] CTD PMID:9094091 Ccnd3 Rat fulvestrant multiple interactions ISO CCND3 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of CCND3 gene and [bisphenol F co-treated with Fulvestrant] results in increased methylation of CCND3 gene CTD PMID:31601247 Ccnd3 Rat fulvestrant multiple interactions EXP 6480464 fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of CCND3 mRNA] and fulvestrant inhibits the reaction [Cadmium results in increased expression of CCND3 mRNA] CTD PMID:24236210 Ccnd3 Rat furazolidone multiple interactions ISO CCND3 (Homo sapiens) 6480464 GADD45A mutant form inhibits the reaction [Furazolidone results in increased expression of CCND3 mRNA] more ... CTD PMID:23112108 and PMID:26095818 Ccnd3 Rat furazolidone increases expression ISO CCND3 (Homo sapiens) 6480464 Furazolidone results in increased expression of CCND3 mRNA and Furazolidone results in increased expression of CCND3 protein CTD PMID:23112108 and PMID:26095818 Ccnd3 Rat gamma-tocopherol decreases expression ISO CCND3 (Homo sapiens) 6480464 Tocopherols results in decreased expression of CCND3 protein CTD PMID:12504091 Ccnd3 Rat gefitinib decreases expression ISO CCND3 (Homo sapiens) 6480464 gefitinib results in decreased expression of CCND3 protein CTD PMID:16740687 Ccnd3 Rat haloperidol increases expression EXP 6480464 Haloperidol results in increased expression of CCND3 mRNA CTD PMID:15860345 Ccnd3 Rat hydroxyurea increases expression ISO CCND3 (Homo sapiens) 6480464 Hydroxyurea results in increased expression of CCND3 protein CTD PMID:11468187 Ccnd3 Rat hypochlorous acid decreases expression ISO Ccnd3 (Mus musculus) 6480464 Hypochlorous Acid results in decreased expression of CCND3 mRNA CTD PMID:19376150 Ccnd3 Rat isoprenaline increases expression ISO Ccnd3 (Mus musculus) 6480464 Isoproterenol results in increased expression of CCND3 mRNA CTD PMID:20003209 Ccnd3 Rat isosilybin A decreases expression ISO CCND3 (Homo sapiens) 6480464 isosilybin A results in decreased expression of CCND3 protein CTD PMID:18435416 Ccnd3 Rat juglone multiple interactions ISO CCND3 (Homo sapiens) 6480464 Ascorbic Acid promotes the reaction [juglone results in decreased expression of CCND3 protein] CTD PMID:29992683 Ccnd3 Rat juglone decreases expression ISO CCND3 (Homo sapiens) 6480464 juglone results in decreased expression of CCND3 protein CTD PMID:29992683 Ccnd3 Rat kinamycin F decreases expression ISO CCND3 (Homo sapiens) 6480464 kinamycin F results in decreased expression of CCND3 mRNA and kinamycin F results in decreased expression of CCND3 protein CTD PMID:20079721 Ccnd3 Rat L-ascorbic acid multiple interactions EXP 6480464 Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCND3 protein] CTD PMID:21621607 Ccnd3 Rat L-ascorbic acid multiple interactions ISO CCND3 (Homo sapiens) 6480464 Ascorbic Acid promotes the reaction [juglone results in decreased expression of CCND3 protein] CTD PMID:29992683 Ccnd3 Rat lithium chloride increases expression ISO Ccnd3 (Mus musculus) 6480464 Lithium Chloride results in increased expression of CCND3 mRNA CTD PMID:27226553 Ccnd3 Rat lovastatin decreases expression ISO CCND3 (Homo sapiens) 6480464 Lovastatin results in decreased expression of CCND3 protein CTD PMID:10502407 Ccnd3 Rat LY294002 multiple interactions ISO CCND3 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IL2 protein results in increased expression of CCND3 mRNA] more ... CTD PMID:15778701 Ccnd3 Rat LY294002 decreases expression ISO Ccnd3 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of CCND3 protein CTD PMID:15601625 Ccnd3 Rat LY294002 decreases expression ISO CCND3 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of CCND3 protein CTD PMID:14757120 Ccnd3 Rat lycorine decreases expression ISO CCND3 (Homo sapiens) 6480464 lycorine results in decreased expression of CCND3 mRNA CTD PMID:23376478 Ccnd3 Rat methimazole increases expression EXP 6480464 Methimazole results in increased expression of CCND3 mRNA CTD PMID:30047161 Ccnd3 Rat methoxyacetic acid multiple interactions ISO CCND3 (Homo sapiens) 6480464 [1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in decreased expression of CCND3 protein CTD PMID:26006246 Ccnd3 Rat methyl methanesulfonate increases expression ISO CCND3 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of CCND3 mRNA CTD PMID:23649840 Ccnd3 Rat methylazoxymethanol increases expression ISO Ccnd3 (Mus musculus) 6480464 methylazoxymethanol results in increased expression of CCND3 mRNA CTD PMID:17107856 Ccnd3 Rat methylmercury chloride decreases expression ISO Ccnd3 (Mus musculus) 6480464 methylmercuric chloride results in decreased expression of CCND3 mRNA CTD PMID:20061341 Ccnd3 Rat methylmercury chloride increases expression ISO CCND3 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of CCND3 mRNA CTD PMID:28001369 Ccnd3 Rat methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of CCND3 protein CTD PMID:17760861 Ccnd3 Rat mono(2-ethylhexyl) phthalate multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCND3 mRNA CTD PMID:31884101 Ccnd3 Rat monobenzyl phthalate multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCND3 mRNA CTD PMID:31884101 Ccnd3 Rat monoethyl phthalate multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCND3 mRNA CTD PMID:31884101 Ccnd3 Rat monosodium L-glutamate increases expression ISO Ccnd3 (Mus musculus) 6480464 Sodium Glutamate results in increased expression of CCND3 mRNA CTD PMID:20111022 Ccnd3 Rat monosodium L-glutamate decreases expression ISO Ccnd3 (Mus musculus) 6480464 Sodium Glutamate results in decreased expression of CCND3 mRNA CTD PMID:22078008 Ccnd3 Rat monosodium L-glutamate multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of CCND3 mRNA CTD PMID:20111022 Ccnd3 Rat N-acetyl-L-cysteine multiple interactions ISO CCND3 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [thymoquinone results in decreased expression of CCND3 protein] CTD PMID:34627931 Ccnd3 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression ISO Ccnd3 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCND3 mRNA CTD PMID:20061341 Ccnd3 Rat N-methyl-N-nitrosourea increases expression EXP 6480464 Methylnitrosourea results in increased expression of CCND3 protein CTD PMID:18155124 Ccnd3 Rat nelfinavir decreases expression ISO CCND3 (Homo sapiens) 6480464 Nelfinavir results in decreased expression of CCND3 protein CTD PMID:19106637 Ccnd3 Rat nickel atom increases expression ISO CCND3 (Homo sapiens) 6480464 Nickel results in increased expression of CCND3 mRNA CTD PMID:24768652 and PMID:25583101 Ccnd3 Rat niclosamide decreases expression ISO Ccnd3 (Mus musculus) 6480464 Niclosamide results in decreased expression of CCND3 mRNA CTD PMID:27226553 Ccnd3 Rat niclosamide decreases expression ISO CCND3 (Homo sapiens) 6480464 Niclosamide results in decreased expression of CCND3 mRNA CTD PMID:22576131 Ccnd3 Rat nitrates multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of CCND3 mRNA CTD PMID:35964746 Ccnd3 Rat orotic acid decreases expression EXP 6480464 Orotic Acid results in decreased expression of CCND3 mRNA CTD PMID:17203948 Ccnd3 Rat ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of CCND3 mRNA CTD PMID:18636392 Ccnd3 Rat palbociclib increases expression ISO CCND3 (Homo sapiens) 6480464 palbociclib results in increased expression of CCND3 protein CTD PMID:20473330 Ccnd3 Rat palbociclib multiple interactions ISO CCND3 (Homo sapiens) 6480464 palbociclib inhibits the reaction [[CDK6 protein binds to CCND3 protein] which results in increased phosphorylation of MEF2D protein] more ... CTD PMID:22094256 Ccnd3 Rat palbociclib multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [CDKN2A gene mutant form results in increased expression of CCND3 protein] which results in increased susceptibility to palbociclib CTD PMID:24098593 Ccnd3 Rat paracetamol multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CCND3 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CCND3 mRNA] CTD PMID:17585979 Ccnd3 Rat paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of CCND3 mRNA CTD PMID:17935786 Ccnd3 Rat parathion multiple interactions ISO CCND3 (Homo sapiens) 6480464 [Parathion co-treated with Atropine] results in increased expression of CCND3 mRNA CTD PMID:17390078 Ccnd3 Rat parathion increases expression ISO CCND3 (Homo sapiens) 6480464 Parathion results in increased expression of CCND3 mRNA CTD PMID:17390078 and PMID:17622325 Ccnd3 Rat PD 0325901 multiple interactions ISO Ccnd3 (Mus musculus) 6480464 mirdametinib inhibits the reaction [camostat results in increased expression of CCND3 protein] CTD PMID:25104499 Ccnd3 Rat pentobarbital decreases expression EXP 6480464 Pentobarbital results in decreased expression of CCND3 protein CTD PMID:19346066 Ccnd3 Rat perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of CCND3 mRNA CTD PMID:18692542 Ccnd3 Rat perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of CCND3 mRNA CTD PMID:19162173 Ccnd3 Rat perfluorooctanoic acid increases expression ISO Ccnd3 (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of CCND3 mRNA CTD PMID:36152675 Ccnd3 Rat perfluorooctanoic acid decreases expression ISO CCND3 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of CCND3 mRNA CTD PMID:36326898 Ccnd3 Rat phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of CCND3 protein CTD PMID:12163013 Ccnd3 Rat phenylephrine multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased expression of CCND3 protein] CTD PMID:12163013 Ccnd3 Rat phenylmercury acetate increases expression ISO CCND3 (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of CCND3 mRNA CTD PMID:26272509 Ccnd3 Rat phenylmercury acetate multiple interactions ISO CCND3 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCND3 mRNA CTD PMID:27188386 Ccnd3 Rat phorbol 13-acetate 12-myristate increases expression ISO CCND3 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased expression of CCND3 protein CTD PMID:12421932 Ccnd3 Rat phorbol 13-acetate 12-myristate multiple interactions ISO CCND3 (Homo sapiens) 6480464 4-(2-(5 more ... CTD PMID:12421932 Ccnd3 Rat picrotoxin increases expression EXP 6480464 Picrotoxin results in increased expression of CCND3 mRNA CTD PMID:15170462 Ccnd3 Rat pioglitazone decreases expression ISO CCND3 (Homo sapiens) 6480464 pioglitazone results in decreased expression of CCND3 protein CTD PMID:15729575 Ccnd3 Rat pirinixic acid multiple interactions ISO Ccnd3 (Mus musculus) 6480464 RXRA protein promotes the reaction [pirinixic acid results in increased expression of CCND3 mRNA] and RXRA protein promotes the reaction [pirinixic acid results in increased expression of CCND3 protein] CTD PMID:19176532 Ccnd3 Rat pirinixic acid increases expression ISO Ccnd3 (Mus musculus) 6480464 pirinixic acid results in increased expression of CCND3 mRNA and pirinixic acid results in increased expression of CCND3 protein CTD PMID:18301758 more ... Ccnd3 Rat piroxicam decreases expression ISO CCND3 (Homo sapiens) 6480464 Piroxicam results in decreased expression of CCND3 mRNA CTD PMID:21858171 Ccnd3 Rat potassium dichromate decreases expression EXP 6480464 Potassium Dichromate results in decreased expression of CCND3 mRNA CTD PMID:26348139 Ccnd3 Rat progesterone increases expression EXP 6480464 Progesterone results in increased expression of CCND3 mRNA CTD PMID:17170212 Ccnd3 Rat quercetin decreases expression ISO CCND3 (Homo sapiens) 6480464 Quercetin results in decreased expression of CCND3 mRNA CTD PMID:14715546 Ccnd3 Rat quercetin multiple interactions ISO CCND3 (Homo sapiens) 6480464 [Cisplatin co-treated with Quercetin] results in increased expression of CCND3 mRNA CTD PMID:27514524 Ccnd3 Rat resveratrol decreases expression ISO CCND3 (Homo sapiens) 6480464 resveratrol results in decreased expression of CCND3 protein CTD PMID:18089832 Ccnd3 Rat resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of CCND3 protein CTD PMID:22104698 Ccnd3 Rat Ro 41-5253 multiple interactions ISO CCND3 (Homo sapiens) 6480464 Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [CPG-oligonucleotide results in increased expression of CCND3 protein]] CTD PMID:17209053 Ccnd3 Rat rotenone decreases expression ISO CCND3 (Homo sapiens) 6480464 Rotenone results in decreased expression of CCND3 mRNA CTD PMID:33512557 Ccnd3 Rat rottlerin multiple interactions ISO CCND3 (Homo sapiens) 6480464 [sorafenib co-treated with rottlerin] results in decreased expression of CCND3 protein CTD PMID:16959960 Ccnd3 Rat SB 203580 multiple interactions ISO CCND3 (Homo sapiens) 6480464 SB 203580 inhibits the reaction [Furazolidone results in increased expression of CCND3 mRNA] and SB 203580 inhibits the reaction [Furazolidone results in increased expression of CCND3 protein] CTD PMID:23112108 Ccnd3 Rat SB 431542 multiple interactions ISO CCND3 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCND3 mRNA CTD PMID:27188386 Ccnd3 Rat silibinin multiple interactions ISO CCND3 (Homo sapiens) 6480464 [Silybin co-treated with Arsenic] results in decreased expression of CCND3 protein CTD PMID:25868784 Ccnd3 Rat silibinin decreases expression ISO CCND3 (Homo sapiens) 6480464 Silybin results in decreased expression of CCND3 protein CTD PMID:18435416 Ccnd3 Rat silicon dioxide decreases expression ISO CCND3 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of CCND3 mRNA CTD PMID:25895662 Ccnd3 Rat sirolimus multiple interactions ISO CCND3 (Homo sapiens) 6480464 [Sirolimus co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] inhibits the reaction [IL2 protein results in increased expression of CCND3 protein] and Sirolimus inhibits the reaction [IL2 protein results in increased expression of CCND3 mRNA] CTD PMID:15778701 Ccnd3 Rat sirolimus decreases expression ISO CCND3 (Homo sapiens) 6480464 Sirolimus results in decreased expression of CCND3 mRNA and Sirolimus results in decreased expression of CCND3 protein CTD PMID:12393642 more ... Ccnd3 Rat sirolimus multiple interactions ISO Ccnd3 (Mus musculus) 6480464 Sirolimus inhibits the reaction [KITL protein results in increased expression of CCND3 protein] CTD PMID:10849422 Ccnd3 Rat sirolimus decreases stability ISO CCND3 (Homo sapiens) 6480464 Sirolimus results in decreased stability of CCND3 mRNA CTD PMID:15882288 Ccnd3 Rat sodium arsenite increases expression ISO CCND3 (Homo sapiens) 6480464 sodium arsenite results in increased expression of CCND3 mRNA CTD PMID:20886546 more ... Ccnd3 Rat sodium arsenite affects expression ISO CCND3 (Homo sapiens) 6480464 sodium arsenite affects the expression of CCND3 mRNA CTD PMID:34032870 Ccnd3 Rat sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of CCND3 mRNA CTD PMID:11241755 Ccnd3 Rat sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of CCND3 mRNA CTD PMID:12325037 Ccnd3 Rat sorafenib multiple interactions ISO CCND3 (Homo sapiens) 6480464 [sorafenib co-treated with rottlerin] results in decreased expression of CCND3 protein CTD PMID:16959960 Ccnd3 Rat sorafenib decreases expression ISO CCND3 (Homo sapiens) 6480464 sorafenib results in decreased expression of CCND3 protein CTD PMID:16959960 and PMID:19001435 Ccnd3 Rat sulfadimethoxine increases expression EXP 6480464 Sulfadimethoxine results in increased expression of CCND3 mRNA CTD PMID:30047161 Ccnd3 Rat sulforaphane increases expression ISO CCND3 (Homo sapiens) 6480464 sulforaphane results in increased expression of CCND3 mRNA CTD PMID:26833863 Ccnd3 Rat sulforaphane multiple interactions ISO Ccnd3 (Mus musculus) 6480464 sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of CCND3 protein] CTD PMID:33007382 Ccnd3 Rat tamoxifen affects expression ISO Ccnd3 (Mus musculus) 6480464 Tamoxifen affects the expression of CCND3 mRNA CTD PMID:17555576 Ccnd3 Rat tamoxifen multiple interactions ISO Ccnd3 (Mus musculus) 6480464 Tamoxifen inhibits the reaction [Estradiol affects the expression of CCND3 mRNA] CTD PMID:9094091 Ccnd3 Rat Tesaglitazar increases expression EXP 6480464 tesaglitazar results in increased expression of CCND3 mRNA CTD PMID:21270424 Ccnd3 Rat tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of CCND3 mRNA CTD PMID:31150632 Ccnd3 Rat thymoquinone decreases expression ISO CCND3 (Homo sapiens) 6480464 thymoquinone results in decreased expression of CCND3 protein CTD PMID:32112862 and PMID:34627931 Ccnd3 Rat thymoquinone multiple interactions ISO CCND3 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [thymoquinone results in decreased expression of CCND3 protein] CTD PMID:34627931 Ccnd3 Rat titanium dioxide decreases expression ISO Ccnd3 (Mus musculus) 6480464 titanium dioxide results in decreased expression of CCND3 mRNA CTD PMID:29264374 Ccnd3 Rat tocopherol decreases expression ISO CCND3 (Homo sapiens) 6480464 Tocopherols results in decreased expression of CCND3 protein CTD PMID:12504091 Ccnd3 Rat tolbutamide increases expression EXP 6480464 Tolbutamide results in increased expression of CCND3 protein CTD PMID:16718685 Ccnd3 Rat Tomentosin decreases expression ISO CCND3 (Homo sapiens) 6480464 tomentosin results in decreased expression of CCND3 protein CTD PMID:32787465 Ccnd3 Rat Tributyltin oxide decreases expression ISO Ccnd3 (Mus musculus) 6480464 bis(tri-n-butyltin)oxide results in decreased expression of CCND3 mRNA CTD PMID:18958704 Ccnd3 Rat Tributyltin oxide decreases expression EXP 6480464 bis(tri-n-butyltin)oxide results in decreased expression of CCND3 mRNA CTD PMID:17553608 Ccnd3 Rat trichloroethene multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of CCND3 protein more ... CTD PMID:15363585 and PMID:33007382 Ccnd3 Rat trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of CCND3 mRNA CTD PMID:33387578 Ccnd3 Rat trichloroethene increases expression ISO Ccnd3 (Mus musculus) 6480464 Trichloroethylene results in increased expression of CCND3 mRNA CTD PMID:15363585 Ccnd3 Rat trichostatin A multiple interactions ISO CCND3 (Homo sapiens) 6480464 trichostatin A results in increased expression of and results in increased stability of CCND3 protein CTD PMID:15179185 Ccnd3 Rat triphenyl phosphate affects expression ISO CCND3 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of CCND3 mRNA CTD PMID:37042841 Ccnd3 Rat triptonide increases expression ISO Ccnd3 (Mus musculus) 6480464 triptonide results in increased expression of CCND3 mRNA CTD PMID:33045310 Ccnd3 Rat troglitazone multiple interactions ISO CCND3 (Homo sapiens) 6480464 Aspirin promotes the reaction [troglitazone results in decreased expression of CCND3 protein] and troglitazone promotes the reaction [Aspirin results in decreased expression of CCND3 protein] CTD PMID:19908241 Ccnd3 Rat troglitazone decreases expression ISO CCND3 (Homo sapiens) 6480464 troglitazone results in decreased expression of CCND3 protein CTD PMID:15729575 and PMID:19908241 Ccnd3 Rat tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions ISO CCND3 (Homo sapiens) 6480464 [Parathion co-treated with Atropine] results in increased expression of CCND3 mRNA CTD PMID:17390078 Ccnd3 Rat Tryptanthrine decreases expression ISO CCND3 (Homo sapiens) 6480464 tryptanthrine results in decreased expression of CCND3 protein CTD PMID:23500671 Ccnd3 Rat urethane increases expression ISO CCND3 (Homo sapiens) 6480464 Urethane results in increased expression of CCND3 mRNA CTD PMID:28818685 Ccnd3 Rat ursodeoxycholic acid decreases expression ISO CCND3 (Homo sapiens) 6480464 Ursodeoxycholic Acid results in decreased expression of CCND3 protein CTD PMID:17461466 Ccnd3 Rat ursolic acid decreases expression ISO CCND3 (Homo sapiens) 6480464 Ursolic Acid results in decreased expression of CCND3 protein CTD PMID:24802810 Ccnd3 Rat usnic acid decreases expression ISO CCND3 (Homo sapiens) 6480464 usnic acid results in decreased expression of CCND3 protein CTD PMID:27369375 Ccnd3 Rat valproic acid increases expression ISO CCND3 (Homo sapiens) 6480464 Valproic Acid results in increased expression of CCND3 mRNA CTD PMID:29154799 Ccnd3 Rat valproic acid decreases expression ISO CCND3 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of CCND3 mRNA CTD PMID:22580532 Ccnd3 Rat vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of CCND3 mRNA CTD PMID:19015723 Ccnd3 Rat vitamin E affects expression EXP 6480464 Vitamin E affects the expression of CCND3 mRNA CTD PMID:15370891 Ccnd3 Rat wortmannin affects localization ISO Ccnd3 (Mus musculus) 6480464 wortmannin affects the localization of CCND3 protein CTD PMID:17129604 Ccnd3 Rat wortmannin multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [wortmannin co-treated with Imatinib Mesylate] affects the localization of CCND3 protein and wortmannin inhibits the reaction [KITL protein results in increased expression of CCND3 protein] CTD PMID:10849422 and PMID:17129604 Ccnd3 Rat XAV939 decreases expression ISO Ccnd3 (Mus musculus) 6480464 XAV939 results in decreased expression of CCND3 mRNA CTD PMID:27226553 Ccnd3 Rat Y-27632 decreases expression ISO CCND3 (Homo sapiens) 6480464 Y 27632 results in decreased expression of CCND3 protein CTD PMID:32417439 Ccnd3 Rat Y-27632 multiple interactions ISO CCND3 (Homo sapiens) 6480464 Y 27632 promotes the reaction [4-amino-2-trifluoromethyl-phenyl retinate results in decreased expression of CCND3 protein] CTD PMID:32417439 Ccnd3 Rat ziram decreases expression EXP 6480464 Ziram results in decreased expression of CCND3 mRNA CTD PMID:28973382 Ccnd3 Rat zoledronic acid multiple interactions ISO Ccnd3 (Mus musculus) 6480464 [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCND3 protein CTD PMID:19789217 Ccnd3 Rat zoledronic acid decreases expression ISO Ccnd3 (Mus musculus) 6480464 zoledronic acid results in decreased expression of CCND3 protein CTD PMID:19789217
Imported Annotations - KEGG (archival)
(aminomethyl)phosphonic acid (ISO) (S)-amphetamine (ISO) 1,2-dimethylhydrazine (ISO) 14-Deoxy-11,12-didehydroandrographolide (ISO) 15-deoxy-Delta(12,14)-prostaglandin J2 (ISO) 17alpha-ethynylestradiol (ISO) 17beta-estradiol (EXP,ISO) 2,3,7,8-tetrachlorodibenzodioxine (ISO) 2,3,7,8-Tetrachlorodibenzofuran (ISO) 2-methoxy-17beta-estradiol (ISO) 2-methoxyethanol (EXP) 3,3',5,5'-tetrabromobisphenol A (EXP) 3,3'-diindolylmethane (ISO) 4,4'-diaminodiphenylmethane (ISO) 4,4'-sulfonyldiphenol (EXP,ISO) 4-hydroxynon-2-enal (ISO) 5-fluorouracil (ISO) 6-propyl-2-thiouracil (EXP) 9-cis-retinoic acid (ISO) acetylleucyl-leucyl-norleucinal (ISO) acetylsalicylic acid (ISO) acteoside (ISO) aflatoxin B1 (ISO) alendronic acid (ISO) all-trans-retinoic acid (EXP,ISO) Allylamine (EXP) amitrole (EXP) ammonium chloride (EXP) aniline (EXP) aristolochic acid A (ISO) arotinoid acid (ISO) arsane (ISO) arsenic atom (ISO) arsenite(3-) (ISO) arsenous acid (ISO) atrazine (ISO) atropine (ISO) benzene (ISO) benzo[a]pyrene (ISO) benzo[b]fluoranthene (ISO) benzoates (ISO) beta-lapachone (ISO) biotin (ISO) biphenyl-4-amine (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) bisphenol F (EXP,ISO) bosutinib (ISO) bucladesine (EXP) butan-1-ol (ISO) Butylparaben (ISO) butyric acid (EXP) cadmium atom (EXP,ISO) cadmium dichloride (EXP,ISO) calycosin (ISO) camostat (ISO) cannabidiol (ISO) carbamazepine (ISO) carbon nanotube (ISO) CGP 52608 (ISO) chlorohydrocarbon (ISO) chloroprene (ISO) chlorpromazine (ISO) chromium(6+) (EXP) cisplatin (ISO) clofibrate (EXP,ISO) clozapine (EXP) cobalt dichloride (ISO) cocaine (EXP) copper atom (ISO) copper(0) (ISO) curcumin (ISO) cycloheximide (ISO) cyclophosphamide (ISO) cyclosporin A (ISO) cypermethrin (ISO) cytarabine (ISO) daunorubicin (ISO) deguelin (ISO) desferrioxamine B (ISO) dexamethasone (ISO) diarsenic trioxide (ISO) Dibutyl phosphate (ISO) dibutyl phthalate (EXP) dichlorine (EXP) diclofenac (ISO) diethylstilbestrol (ISO) diuron (ISO) dorsomorphin (ISO) doxorubicin (ISO) dronedarone (ISO) ethyl methanesulfonate (ISO) everolimus (ISO) fenamidone (ISO) fluoxetine (ISO) flutamide (EXP) folic acid (ISO) formaldehyde (ISO) fulvestrant (EXP,ISO) furazolidone (ISO) gamma-tocopherol (ISO) gefitinib (ISO) haloperidol (EXP) hydroxyurea (ISO) hypochlorous acid (ISO) isoprenaline (ISO) isosilybin A (ISO) juglone (ISO) kinamycin F (ISO) L-ascorbic acid (EXP,ISO) lithium chloride (ISO) lovastatin (ISO) LY294002 (ISO) lycorine (ISO) methimazole (EXP) methoxyacetic acid (ISO) methyl methanesulfonate (ISO) methylazoxymethanol (ISO) methylmercury chloride (EXP,ISO) mono(2-ethylhexyl) phthalate (ISO) monobenzyl phthalate (ISO) monoethyl phthalate (ISO) monosodium L-glutamate (ISO) N-acetyl-L-cysteine (ISO) N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO) N-methyl-N-nitrosourea (EXP) nelfinavir (ISO) nickel atom (ISO) niclosamide (ISO) nitrates (ISO) orotic acid (EXP) ozone (EXP) palbociclib (ISO) paracetamol (ISO) paraquat (EXP) parathion (ISO) PD 0325901 (ISO) pentobarbital (EXP) perfluorooctane-1-sulfonic acid (EXP) perfluorooctanoic acid (EXP,ISO) phenylephrine (EXP) phenylmercury acetate (ISO) phorbol 13-acetate 12-myristate (ISO) picrotoxin (EXP) pioglitazone (ISO) pirinixic acid (ISO) piroxicam (ISO) potassium dichromate (EXP) progesterone (EXP) quercetin (ISO) resveratrol (EXP,ISO) Ro 41-5253 (ISO) rotenone (ISO) rottlerin (ISO) SB 203580 (ISO) SB 431542 (ISO) silibinin (ISO) silicon dioxide (ISO) sirolimus (ISO) sodium arsenite (EXP,ISO) sodium dichromate (EXP) sorafenib (ISO) sulfadimethoxine (EXP) sulforaphane (ISO) tamoxifen (ISO) Tesaglitazar (EXP) tetrachloromethane (EXP) thymoquinone (ISO) titanium dioxide (ISO) tocopherol (ISO) tolbutamide (EXP) Tomentosin (ISO) Tributyltin oxide (EXP,ISO) trichloroethene (EXP,ISO) trichostatin A (ISO) triphenyl phosphate (ISO) triptonide (ISO) troglitazone (ISO) tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate (ISO) Tryptanthrine (ISO) urethane (ISO) ursodeoxycholic acid (ISO) ursolic acid (ISO) usnic acid (ISO) valproic acid (ISO) vinclozolin (EXP) vitamin E (EXP) wortmannin (ISO) XAV939 (ISO) Y-27632 (ISO) ziram (EXP) zoledronic acid (ISO)
1.
Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma.
Bergsagel PL, etal., Blood. 2005 Jul 1;106(1):296-303. Epub 2005 Mar 8.
2.
D-type cyclins and G1 progression during liver development in the rat.
Boylan JM and Gruppuso PA, Biochem Biophys Res Commun. 2005 May 13;330(3):722-30.
3.
[Retrospective study of one year of family therapy in a neurological practice (author's transl)]
Gattringer B Nervenarzt 1977 Jun;48(6):326-30.
4.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
6.
Circadian regulation of diverse gene products revealed by mRNA expression profiling of synchronized fibroblasts.
Grundschober C, etal., J Biol Chem 2001 Dec 14;276(50):46751-8.
7.
Induction of D2 and D3 cyclin-encoding genes during promotion of the G1/S transition by prolactin in rat Nb2 cells.
Hosokawa Y, etal., Gene 1994 Sep 30;147(2):249-52.
8.
Increased expression of CDK11p58 and cyclin D3 following spinal cord injury in rats.
Ji Y, etal., Mol Cell Biochem. 2008 Feb;309(1-2):49-60. Epub 2007 Nov 16.
9.
Polymorphic loci of E2F2, CCND1 and CCND3 are associated with HER2 status of breast tumors.
Justenhoven C, etal., Int J Cancer. 2009 May 1;124(9):2077-81.
10.
Expression and prognostic significance of cyclin D3 in ovarian adenocarcinomas.
Levidou G, etal., Int J Gynecol Pathol. 2007 Oct;26(4):410-7.
11.
Cyclin D3 expression in primary Ta/T1 bladder cancer.
Lopez-Beltran A, etal., J Pathol. 2006 May;209(1):106-13.
12.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
13.
Critical role of cyclin D3 in TSH-dependent growth of thyrocytes and in hyperproliferative diseases of the thyroid gland.
Motti ML, etal., Oncogene. 2003 Oct 23;22(48):7576-86.
14.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
15.
Expression of p27((Kip1)), cyclin D3 and Ki67 in BPH, prostate cancer and hormone-treated prostate cancer cells.
Nikoleishvili D, etal., Int Urol Nephrol. 2008;40(4):953-9. Epub 2008 Mar 4.
16.
Differential enantioselective effects of pentyl-4-yn-valproate on spatial learning in the rat, and neurite outgrowth and cyclin D3 expression in vitro.
O'Loinsigh ED, etal., J Neurochem. 2004 Jan;88(2):370-9.
17.
Immunoreactivity of p27(Kip1), cyclin D3, and Ki67 in conventional renal cell carcinoma.
Pertia A, etal., Int Urol Nephrol. 2009;41(2):243-9. Epub 2008 Aug 5.
18.
KEGG Annotation Import Pipeline
Pipeline to import KEGG annotations from KEGG into RGD
19.
Alternative mammary oncogenic pathways are induced by D-type cyclins; MMTV-cyclin D3 transgenic mice develop squamous cell carcinoma.
Pirkmaier A, etal., Oncogene. 2003 Jul 10;22(28):4425-33.
20.
Cyclin D3 mediates synthesis of a hyaluronan matrix that is adhesive for monocytes in mesangial cells stimulated to divide in hyperglycemic medium.
Ren J, etal., J Biol Chem. 2009 Jun 12;284(24):16621-32. Epub 2009 Mar 9.
21.
GOA pipeline
RGD automated data pipeline
22.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
23.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
24.
Differential regulation of cyclins D1 and D3 in hepatocyte proliferation.
Rickheim DG, etal., Hepatology 2002 Jul;36(1):30-8.
25.
The Pezcoller lecture: cancer cell cycles revisited.
Sherr CJ Cancer Res. 2000 Jul 15;60(14):3689-95.
26.
Tentative Sequence Identification Numbers
Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
27.
Cyclins and proliferation markers in early squamous cervical carcinoma.
Van de Putte G, etal., Gynecol Oncol. 2004 Jan;92(1):40-6.
28.
Overexpression of cyclins D1 and D3 during estrogen-induced breast oncogenesis in female ACI rats.
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29.
Differential expression of p16/p21/p27 and cyclin D1/D3, and their relationships to cell proliferation, apoptosis, and tumour progression in invasive ductal carcinoma of the breast.
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30.
Structure and characterization of rat cyclin D3 promoter.
Yang M, etal., Gene 1996 Nov 28;181(1-2):153-9.
Ccnd3 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 9 20,891,696 - 20,987,199 (-) NCBI GRCr8 mRatBN7.2 9 13,394,161 - 13,400,341 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 9 13,394,169 - 13,489,371 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 9 21,973,914 - 21,980,097 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 9 27,038,080 - 27,044,259 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 9 25,337,315 - 25,343,498 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 9 15,404,816 - 15,410,905 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 9 15,404,822 - 15,410,943 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 9 14,326,227 - 14,332,267 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 Celera 9 11,145,441 - 11,151,481 (-) NCBI Celera Cytogenetic Map 9 q12 NCBI
CCND3 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 6 41,934,933 - 42,050,035 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 6 41,934,934 - 42,050,357 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 6 41,902,671 - 42,017,773 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 6 42,010,649 - 42,017,530 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 6 42,010,649 - 42,017,530 NCBI Celera 6 43,455,463 - 43,569,077 (-) NCBI Celera Cytogenetic Map 6 p21.1 NCBI HuRef 6 41,621,515 - 41,734,566 (-) NCBI HuRef CHM1_1 6 41,905,431 - 42,019,143 (-) NCBI CHM1_1 T2T-CHM13v2.0 6 41,763,493 - 41,878,294 (-) NCBI T2T-CHM13v2.0
Ccnd3 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 17 47,815,976 - 47,910,614 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 17 47,815,976 - 47,910,616 (+) Ensembl GRCm39 Ensembl GRCm38 17 47,505,051 - 47,599,689 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 17 47,505,051 - 47,599,691 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 17 47,642,000 - 47,736,638 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 17 47,056,739 - 47,062,880 (+) NCBI MGSCv36 mm8 Celera 17 50,938,969 - 51,036,715 (+) NCBI Celera Cytogenetic Map 17 C NCBI cM Map 17 23.37 NCBI
Ccnd3 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955437 8,268,118 - 8,273,855 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955437 8,266,523 - 8,273,855 (-) NCBI ChiLan1.0 ChiLan1.0
CCND3 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 5 56,426,311 - 56,537,983 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 6 52,296,193 - 52,407,867 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 6 41,518,421 - 41,630,103 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 6 42,820,569 - 42,932,944 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 6 42,820,569 - 42,827,498 (-) Ensembl panpan1.1 panPan2
CCND3 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 12 10,593,786 - 10,688,304 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 12 10,594,712 - 10,600,891 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 12 10,623,109 - 10,717,215 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 12 11,074,540 - 11,169,519 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 12 11,074,547 - 11,169,151 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 12 10,604,536 - 10,698,641 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 12 10,688,499 - 10,783,041 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 12 10,782,466 - 10,877,073 (-) NCBI UU_Cfam_GSD_1.0
Ccnd3 Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024404946 46,073,366 - 46,160,552 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936476 17,879,869 - 17,886,827 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936476 17,799,754 - 17,886,835 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
CCND3 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 7 37,082,097 - 37,181,366 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 7 37,087,336 - 37,182,462 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 7 42,489,107 - 42,493,235 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
CCND3 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 17 30,107,236 - 30,228,449 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 17 30,221,598 - 30,227,452 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666044 41,934,657 - 42,061,231 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Ccnd3
.
Predicted Target Of
Count of predictions: 73 Count of miRNA genes: 64 Interacting mature miRNAs: 65 Transcripts: ENSRNOT00000074217 Prediction methods: Miranda, Rnahybrid Result types: miRGate_prediction
631211 Bw4 Body weight QTL4 5.31 retroperitoneal fat pad mass (VT:0010430) retroperitoneal fat pad weight to body weight ratio (CMO:0000635) 9 5109826 50109826 Rat 10054141 Gmadr4 Adrenal mass QTL 4 2.45 0.0074 adrenal gland mass (VT:0010420) both adrenal glands wet weight (CMO:0000164) 9 1 14209783 Rat 2303559 Gluco54 Glucose level QTL 54 2 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 9 1254084 46254084 Rat 7411609 Foco16 Food consumption QTL 16 25.6 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 9 8952560 53952560 Rat 61450 Ciaa3 CIA Autoantibody QTL 3 6.5 blood autoantibody amount (VT:0003725) calculated serum anti-type 2 collagen antibody titer (CMO:0001279) 9 7954720 22071169 Rat 1578675 Bss17 Bone structure and strength QTL 17 3.8 femur morphology trait (VT:0000559) femoral neck cortical cross-sectional area (CMO:0001702) 9 3368652 13533896 Rat 9589055 Scfw5 Subcutaneous fat weight QTL 5 5.55 0.001 subcutaneous adipose mass (VT:1000472) abdominal subcutaneous fat pad weight (CMO:0002069) 9 1 37999212 Rat 1641911 Alcrsp13 Alcohol response QTL 13 response to alcohol trait (VT:0010489) brain neurotensin receptor 1 density (CMO:0002068) 9 1 43718459 Rat 1354650 Despr5 Despair related QTL 5 4.01 0.0017 locomotor behavior trait (VT:0001392) amount of time spent in voluntary immobility (CMO:0001043) 9 1254084 46254084 Rat 1300124 Cm4 Cardiac mass QTL 4 3.55 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 9 1 40594091 Rat 61425 Cia15 Collagen induced arthritis QTL 15 4.6 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 9 5109826 42921101 Rat 70226 Eae4 Experimental allergic encephalomyelitis QTL 4 nervous system integrity trait (VT:0010566) experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046) 9 1 25661317 Rat 9589158 Gluco65 Glucose level QTL 65 6.82 0.001 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) 9 1 37999212 Rat 10054125 Srcrt7 Stress Responsive Cort QTL 7 3.33 0.0011 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 9 1 87073594 Rat 11353947 Bp392 Blood pressure QTL 392 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 9 7283252 52283252 Rat 7411592 Foco8 Food consumption QTL 8 7.4 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 9 1 37999212 Rat 1331757 Cdexp1 CD45RC expression in CD8 T cells QTL 1 4.3 CD8-positive T cell quantity (VT:0008077) blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990) 9 1024537 67509080 Rat 1298088 Edpm11 Estrogen-dependent pituitary mass QTL 11 2.5 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 9 1 43718459 Rat 9589133 Insul26 Insulin level QTL 26 17.96 0.001 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 9 8952560 53952560 Rat
D8Mgh14
Rat Assembly Chr Position (strand) Source JBrowse Cytogenetic Map 8 q24 UniSTS
D2Mit27
No map positions available.
D9Wox28
Rat Assembly Chr Position (strand) Source JBrowse GRCr8 9 20,898,792 - 20,898,969 (+) Marker Load Pipeline mRatBN7.2 9 13,401,258 - 13,401,435 (+) MAPPER mRatBN7.2 Rnor_6.0 9 15,411,905 - 15,412,081 NCBI Rnor6.0 Rnor_5.0 9 14,333,257 - 14,333,433 UniSTS Rnor5.0 Celera 9 11,152,425 - 11,152,591 UniSTS Cytogenetic Map 8 q24 UniSTS
D9Wox44
Rat Assembly Chr Position (strand) Source JBrowse GRCr8 9 20,898,327 - 20,898,477 (+) Marker Load Pipeline mRatBN7.2 9 13,400,793 - 13,400,943 (+) MAPPER mRatBN7.2 Rnor_6.0 9 15,411,440 - 15,411,589 NCBI Rnor6.0 Rnor_5.0 9 14,332,792 - 14,332,941 UniSTS Rnor5.0 Celera 9 11,151,957 - 11,152,109 UniSTS Cytogenetic Map 8 q24 UniSTS
RH124354
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 9 13,394,166 - 13,394,439 (+) MAPPER mRatBN7.2 Rnor_6.0 9 15,404,822 - 15,405,094 NCBI Rnor6.0 Rnor_5.0 9 14,326,184 - 14,326,456 UniSTS Rnor5.0 Celera 9 11,145,398 - 11,145,670 UniSTS Cytogenetic Map 8 q24 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000074217 ⟹ ENSRNOP00000064704
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 9 13,394,169 - 13,489,371 (-) Ensembl Rnor_6.0 Ensembl 9 15,404,822 - 15,410,943 (-) Ensembl
RefSeq Acc Id:
NM_012766 ⟹ NP_036898
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 9 20,891,696 - 20,897,875 (-) NCBI mRatBN7.2 9 13,394,161 - 13,400,341 (-) NCBI Rnor_6.0 9 15,404,865 - 15,410,905 (-) NCBI Rnor_5.0 9 14,326,227 - 14,332,267 (-) NCBI Celera 9 11,145,441 - 11,151,481 (-) NCBI
Sequence:
TCTCACTCACACGCGACGCGTCGCTTCTCCTAGGACTCGCTAGCCCGCACTCCTGCTCTCACCCGTGAGCCATAGCAGGATGGAGCTGCTGTGTTGCGAGGGCACCCGGCTCGCGCCCCGGGCCGGGC
hide sequence
RefSeq Acc Id:
XM_063266663 ⟹ XP_063122733
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 9 20,891,696 - 20,987,199 (-) NCBI
RefSeq Acc Id:
XM_063266665 ⟹ XP_063122735
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 9 20,891,696 - 20,987,114 (-) NCBI
RefSeq Acc Id:
XM_063266666 ⟹ XP_063122736
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 9 20,891,696 - 20,987,199 (-) NCBI
RefSeq Acc Id:
XM_063266667 ⟹ XP_063122737
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 9 20,891,696 - 20,987,096 (-) NCBI
RefSeq Acc Id:
NP_036898 ⟸ NM_012766
- UniProtKB:
Q63628 (UniProtKB/Swiss-Prot), P48961 (UniProtKB/Swiss-Prot), Q5U321 (UniProtKB/TrEMBL), M0R5N2 (UniProtKB/TrEMBL)
- Sequence:
MELLCCEGTRLAPRAGPDPRLLGDQRVLQSLLRLEERYVPRGSYFQCVQKEIKPHMRKMLAYWMLEVCEEQRCEEDVFPLAMNYLDRYLSCVPTRKAQLQLLGTVCLLLASKLRETTPLTIEKLCIYT
hide sequence
Ensembl Acc Id:
ENSRNOP00000064704 ⟸ ENSRNOT00000074217
RefSeq Acc Id:
XP_063122736 ⟸ XM_063266666
- Peptide Label:
isoform X1
- UniProtKB:
Q63628 (UniProtKB/Swiss-Prot), P48961 (UniProtKB/Swiss-Prot), M0R5N2 (UniProtKB/TrEMBL), Q5U321 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063122733 ⟸ XM_063266663
- Peptide Label:
isoform X1
- UniProtKB:
Q63628 (UniProtKB/Swiss-Prot), P48961 (UniProtKB/Swiss-Prot), M0R5N2 (UniProtKB/TrEMBL), Q5U321 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063122735 ⟸ XM_063266665
- Peptide Label:
isoform X1
- UniProtKB:
Q63628 (UniProtKB/Swiss-Prot), P48961 (UniProtKB/Swiss-Prot), M0R5N2 (UniProtKB/TrEMBL), Q5U321 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063122737 ⟸ XM_063266667
- Peptide Label:
isoform X1
- UniProtKB:
Q63628 (UniProtKB/Swiss-Prot), P48961 (UniProtKB/Swiss-Prot), M0R5N2 (UniProtKB/TrEMBL), Q5U321 (UniProtKB/TrEMBL)
RGD ID: 13696499 Promoter ID: EPDNEW_R7022 Type: initiation region Name: Ccnd3_1 Description: cyclin D3 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 9 15,410,992 - 15,411,052 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2002-06-10
Ccnd3
Cyclin D3
Symbol and Name status set to approved
70586 APPROVED
Note Type
Note
Reference
gene_function
binds both cdk4 and cdk6 in hepatocytes
1298736
gene_physical_interaction
interacts with Cdk4
70761
gene_process
plays a key role in the G1/S transition in cell cycle
70761
gene_regulation
protein amount is regulated at the transcription level and protein half-life is 25 minutes
70761
