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Gene: Cdk6 (cyclin-dependent kinase 6) Rattus norvegicus
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Symbol: Cdk6
Name: cyclin-dependent kinase 6
Description: Exhibits cyclin binding activity. Predicted to be involved in several processes, including hemopoiesis; regulation of gene expression; and regulation of hemopoiesis. Predicted to localize to several cellular components, including the centrosome; cyclin D2-CDK6 complex; and ruffle. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; malignant glioma; pancreatic adenocarcinoma; pancreatic ductal carcinoma; and primary autosomal recessive microcephaly 12. Orthologous to human CDK6 (cyclin dependent kinase 6); PARTICIPATES IN G1/S transition pathway; cell cycle pathway, mitotic; ceramide signaling pathway; INTERACTS WITH (RS)-amphetamine; (Z)-3-butylidenephthalide; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cell division protein kinase 6
Orthologs:
Homo sapiens (human) : CDK6 (cyclin dependent kinase 6)  HGNC  Alliance
Mus musculus (house mouse) : Cdk6 (cyclin-dependent kinase 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk6 (cyclin dependent kinase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK6 (cyclin dependent kinase 6)
Canis lupus familiaris (dog) : CDK6 (cyclin dependent kinase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk6 (cyclin dependent kinase 6)
Sus scrofa (pig) : CDK6 (cyclin dependent kinase 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0427,781,728 - 27,969,653 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0427,685,042 - 27,872,388 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4427,362,656 - 27,618,006 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1427,471,179 - 27,635,330 (-)NCBI
Celera426,070,823 - 26,248,747 (-)NCBICelera
Cytogenetic Map4q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cdk6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621121
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.