Ccnd3 (cyclin D3) - Rat Genome Database

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Gene: Ccnd3 (cyclin D3) Heterocephalus glaber
Analyze
Symbol: Ccnd3
Name: cyclin D3
RGD ID: 18923481
Description: ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase activator activity (ortholog); cyclin-dependent protein serine/threonine kinase activity (ortholog); protein kinase binding (ortholog); INVOLVED IN G1/S transition of mitotic cell cycle (ortholog); hyaluronan biosynthetic process (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN G1/S transition pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); cervix carcinoma (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN cyclin D3-CDK4 complex (ortholog); cyclin D3-CDK6 complex (ortholog); cyclin-dependent protein kinase holoenzyme complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: G1/S-specific cyclin-D3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475417,148,076 - 17,194,000 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475417,148,108 - 17,194,626 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Ccnd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475417,148,076 - 17,194,000 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475417,148,108 - 17,194,626 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CCND3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38641,934,933 - 42,050,035 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl641,934,934 - 42,050,357 (-)EnsemblGRCh38hg38GRCh38
GRCh37641,902,671 - 42,017,773 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36642,010,649 - 42,017,530 (-)NCBINCBI36Build 36hg18NCBI36
Build 34642,010,649 - 42,017,530NCBI
Celera643,455,463 - 43,569,077 (-)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef641,621,515 - 41,734,566 (-)NCBIHuRef
CHM1_1641,905,431 - 42,019,143 (-)NCBICHM1_1
T2T-CHM13v2.0641,763,493 - 41,878,294 (-)NCBIT2T-CHM13v2.0
Ccnd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391747,815,976 - 47,910,614 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1747,815,976 - 47,910,616 (+)EnsemblGRCm39 Ensembl
GRCm381747,505,051 - 47,599,689 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1747,505,051 - 47,599,691 (+)EnsemblGRCm38mm10GRCm38
MGSCv371747,642,000 - 47,736,638 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361747,056,739 - 47,062,880 (+)NCBIMGSCv36mm8
Celera1750,938,969 - 51,036,715 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1723.37NCBI
Ccnd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8920,891,696 - 20,987,199 (-)NCBIGRCr8
mRatBN7.2913,394,161 - 13,400,341 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl913,394,169 - 13,489,371 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx921,973,914 - 21,980,097 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0927,038,080 - 27,044,259 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0925,337,315 - 25,343,498 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0915,404,816 - 15,410,905 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl915,404,822 - 15,410,943 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0914,326,227 - 14,332,267 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera911,145,441 - 11,151,481 (-)NCBICelera
Cytogenetic Map9q12NCBI
Ccnd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554378,268,118 - 8,273,855 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554378,266,523 - 8,273,855 (-)NCBIChiLan1.0ChiLan1.0
CCND3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2556,426,311 - 56,537,983 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1652,296,193 - 52,407,867 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0641,518,421 - 41,630,103 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1642,820,569 - 42,932,944 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl642,820,569 - 42,827,498 (-)Ensemblpanpan1.1panPan2
CCND3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11210,593,786 - 10,688,304 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1210,594,712 - 10,600,891 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1210,623,109 - 10,717,215 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01211,074,540 - 11,169,519 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1211,074,547 - 11,169,151 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11210,604,536 - 10,698,641 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01210,688,499 - 10,783,041 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01210,782,466 - 10,877,073 (-)NCBIUU_Cfam_GSD_1.0
Ccnd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494646,073,366 - 46,160,552 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647617,879,869 - 17,886,827 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647617,799,754 - 17,886,835 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCND3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl737,082,097 - 37,181,366 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1737,087,336 - 37,182,462 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2742,489,107 - 42,493,235 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCND3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11730,107,236 - 30,228,449 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1730,221,598 - 30,227,452 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604441,934,657 - 42,061,231 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000024732   ⟹   ENSHGLP00000024511
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475417,148,076 - 17,194,000 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000024733   ⟹   ENSHGLP00000024512
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475417,188,353 - 17,194,000 (+)Ensembl
RefSeq Acc Id: XM_004846583   ⟹   XP_004846640
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475417,188,325 - 17,194,626 (+)NCBI
RefSeq Acc Id: XM_004846585   ⟹   XP_004846642
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475417,148,110 - 17,194,626 (+)NCBI
RefSeq Acc Id: XM_004846586   ⟹   XP_004846643
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475417,148,108 - 17,194,626 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004846640 (Get FASTA)   NCBI Sequence Viewer  
  XP_004846642 (Get FASTA)   NCBI Sequence Viewer  
  XP_004846643 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB10836 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000024511
  ENSHGLP00000024512
RefSeq Acc Id: XP_004846643   ⟸   XM_004846586
- Peptide Label: isoform X3
RefSeq Acc Id: XP_004846642   ⟸   XM_004846585
- Peptide Label: isoform X2
- UniProtKB: G5BNJ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004846640   ⟸   XM_004846583
- Peptide Label: isoform X1
Ensembl Acc Id: ENSHGLP00000024511   ⟸   ENSHGLT00000024732
Ensembl Acc Id: ENSHGLP00000024512   ⟸   ENSHGLT00000024733


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017469 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000024732 ENTREZGENE
  ENSHGLT00000024733 ENTREZGENE
Gene3D-CATH Cyclin-like UniProtKB/TrEMBL
InterPro Cyclin UniProtKB/TrEMBL
  Cyclin-like_sf UniProtKB/TrEMBL
  Cyclin_C-dom UniProtKB/TrEMBL
  Cyclin_N UniProtKB/TrEMBL
NCBI Gene Ccnd3 ENTREZGENE
PANTHER PTHR10177 UniProtKB/TrEMBL
  PTHR10177:SF65 UniProtKB/TrEMBL
Pfam Cyclin_C UniProtKB/TrEMBL
  Cyclin_N UniProtKB/TrEMBL
SMART Cyclin_C UniProtKB/TrEMBL
Superfamily-SCOP SSF47954 UniProtKB/TrEMBL
UniProt A0AAX6P9Q6_HETGA UniProtKB/TrEMBL
  A0AAX6PA57_HETGA UniProtKB/TrEMBL
  G5BNJ0 ENTREZGENE, UniProtKB/TrEMBL