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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | increases expression | ISO | RGD:1614323 | 6480464 | 1, 2-Dimethylhydrazine results in increased expression of PTK7 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:1614323 | 6480464 | Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in increased expression of PTK7 mRNA] | CTD | PMID:22206623 | 1,3-dinitrobenzene | increases expression | EXP | | 6480464 | 3-dinitrobenzene results in increased expression of PTK7 mRNA | CTD | PMID:21983209 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of PTK7 mRNA | CTD | PMID:30723492 | 17beta-estradiol | multiple interactions | ISO | RGD:1344975 | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PTK7 mRNA | CTD | PMID:20823114 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PTK7 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1614323 | 6480464 | Tetrachlorodibenzodioxin affects the expression of PTK7 mRNA | CTD | PMID:26377647 | 4,4'-diaminodiphenylmethane | increases expression | ISO | RGD:1614323 | 6480464 | 4, 4'-diaminodiphenylmethane results in increased expression of PTK7 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | RGD:1614323 | 6480464 | bis(4-hydroxyphenyl)sulfone results in decreased methylation of PTK7 exon | CTD | PMID:33297965 | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:1614323 | 6480464 | Fenretinide results in increased expression of PTK7 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of PTK7 mRNA | CTD | PMID:24780913 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of PTK7 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | ISO | RGD:1344975 | 6480464 | Acrylamide results in decreased expression of PTK7 mRNA | CTD | PMID:32763439 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of PTK7 mRNA | CTD | PMID:25378103 | aflatoxin B1 | decreases methylation | ISO | RGD:1344975 | 6480464 | Aflatoxin B1 results in decreased methylation of PTK7 intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | decreases methylation | ISO | RGD:1344975 | 6480464 | aflatoxin B2 results in decreased methylation of PTK7 intron | CTD | PMID:30157460 | all-trans-retinoic acid | increases expression | ISO | RGD:1344975 | 6480464 | Tretinoin results in increased expression of PTK7 mRNA | CTD | PMID:23830798 | all-trans-retinoic acid | decreases expression | ISO | RGD:1344975 | 6480464 | Tretinoin results in decreased expression of PTK7 mRNA | CTD | PMID:33167477 | atrazine | increases expression | ISO | RGD:1344975 | 6480464 | Atrazine results in increased expression of PTK7 mRNA | CTD | PMID:22378314 | benzatropine | decreases expression | ISO | RGD:1344975 | 6480464 | Benztropine results in decreased expression of PTK7 protein | CTD | PMID:34122009 | benzo[a]pyrene | decreases methylation | ISO | RGD:1344975 | 6480464 | Benzo(a)pyrene results in decreased methylation of PTK7 promoter | CTD | PMID:27901495 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of PTK7 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PTK7 mRNA | CTD | PMID:34947998 | bisphenol A | affects expression | ISO | RGD:1344975 | 6480464 | bisphenol A affects the expression of PTK7 mRNA | CTD | PMID:30903817 | bisphenol A | increases expression | ISO | RGD:1344975 | 6480464 | bisphenol A results in increased expression of PTK7 mRNA | CTD | PMID:29275510 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of PTK7 gene | CTD | PMID:28505145 | bucladesine | multiple interactions | ISO | RGD:1344975 | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PTK7 mRNA | CTD | PMID:20823114 | cisplatin | multiple interactions | ISO | RGD:1344975 | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of PTK7 mRNA | CTD | PMID:27392435 | cisplatin | increases expression | ISO | RGD:1344975 | 6480464 | Cisplatin results in increased expression of PTK7 mRNA | CTD | PMID:27392435 | copper(II) sulfate | decreases expression | ISO | RGD:1344975 | 6480464 | Copper Sulfate results in decreased expression of PTK7 mRNA | CTD | PMID:19549813 | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of PTK7 mRNA | CTD | PMID:26577399 | cyclosporin A | decreases expression | ISO | RGD:1344975 | 6480464 | Cyclosporine results in decreased expression of PTK7 mRNA | CTD | PMID:25562108 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of PTK7 mRNA | CTD | PMID:21266533 | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of PTK7 mRNA | CTD | PMID:30307764 | folic acid | multiple interactions | ISO | RGD:1614323 | 6480464 | Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in increased expression of PTK7 mRNA] | CTD | PMID:22206623 | folic acid | decreases expression | ISO | RGD:1614323 | 6480464 | Folic Acid results in decreased expression of PTK7 mRNA | CTD | PMID:25629700 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of PTK7 mRNA | CTD | PMID:27387713 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of PTK7 mRNA | CTD | PMID:33387578 | ivermectin | decreases expression | ISO | RGD:1344975 | 6480464 | Ivermectin results in decreased expression of PTK7 protein | CTD | PMID:32959892 | medroxyprogesterone acetate | multiple interactions | ISO | RGD:1344975 | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PTK7 mRNA | CTD | PMID:20823114 | methotrexate | affects expression | ISO | RGD:1614323 | 6480464 | Methotrexate affects the expression of PTK7 mRNA | CTD | PMID:18502557 | microcystin-LR | increases expression | EXP | | 6480464 | cyanoginosin LR results in increased expression of PTK7 mRNA | CTD | PMID:34740672 | microcystin-LR | multiple interactions | EXP | | 6480464 | [Dietary Fats co-treated with Cholesterol, Dietary co-treated with cyanoginosin LR] results in increased expression of PTK7 mRNA | CTD | PMID:34740672 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of PTK7 mRNA | CTD | PMID:25729387 | oxaliplatin | increases expression | EXP | | 6480464 | oxaliplatin results in increased expression of PTK7 mRNA | CTD | PMID:25729387 | paracetamol | decreases expression | ISO | RGD:1344975 | 6480464 | Acetaminophen results in decreased expression of PTK7 mRNA | CTD | PMID:26690555 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PTK7 mRNA | CTD | PMID:33387578 | PCB138 | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:23829299 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | RGD:1614323 | 6480464 | perfluorooctane sulfonic acid results in decreased expression of PTK7 protein | CTD | PMID:26178269 | resveratrol | multiple interactions | ISO | RGD:1344975 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of PTK7 mRNA | CTD | PMID:23557933 | SB 431542 | increases expression | ISO | RGD:1344975 | 6480464 | 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of PTK7 protein | CTD | PMID:25670856 | sodium arsenite | affects methylation | ISO | RGD:1344975 | 6480464 | sodium arsenite affects the methylation of PTK7 gene | CTD | PMID:28589171 | sodium fluoride | decreases expression | ISO | RGD:1614323 | 6480464 | Sodium Fluoride results in decreased expression of PTK7 mRNA | CTD | PMID:27862939 | sunitinib | decreases expression | ISO | RGD:1344975 | 6480464 | Sunitinib results in decreased expression of PTK7 mRNA | CTD | PMID:31533062 | temozolomide | increases expression | ISO | RGD:1344975 | 6480464 | Temozolomide results in increased expression of PTK7 mRNA | CTD | PMID:31758290 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of PTK7 mRNA | CTD | PMID:25729387 | valproic acid | increases expression | ISO | RGD:1344975 | 6480464 | Valproic Acid results in increased expression of PTK7 mRNA | CTD | PMID:29154799 | valproic acid | increases expression | ISO | RGD:1614323 | 6480464 | Valproic Acid results in increased expression of PTK7 mRNA | CTD | PMID:21427059 | valproic acid | increases methylation | ISO | RGD:1344975 | 6480464 | Valproic Acid results in increased methylation of PTK7 gene | CTD | PMID:29154799 | |