Ptk7 (protein tyrosine kinase 7) - Rat Genome Database

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Gene: Ptk7 (protein tyrosine kinase 7) Rattus norvegicus
Analyze
Symbol: Ptk7
Name: protein tyrosine kinase 7
RGD ID: 1310472
Description: Predicted to enable non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in several processes, including cellular response to retinoic acid; positive regulation of canonical Wnt signaling pathway; and positive regulation of neuron projection development. Predicted to act upstream of or within several processes, including cochlea morphogenesis; heart development; and morphogenesis of an epithelium. Predicted to be located in several cellular components, including cell-cell junction; cytosol; and intracellular membrane-bounded organelle. Predicted to be active in plasma membrane. Orthologous to human PTK7 (protein tyrosine kinase 7 (inactive)); PARTICIPATES IN Wnt signaling, the planar cell polarity pathway; INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: inactive tyrosine-protein kinase 7; LOC301242; PTK7 protein tyrosine kinase 7; tyrosine-protein kinase-like 7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8921,849,756 - 21,916,077 (+)NCBIGRCr8
mRatBN7.2914,352,155 - 14,418,473 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl914,351,202 - 14,418,494 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx922,936,018 - 23,002,174 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0927,998,899 - 28,065,207 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0926,299,393 - 26,365,553 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0916,662,588 - 16,729,888 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl916,702,460 - 16,729,030 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0915,569,249 - 15,634,907 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.199,683,466 - 9,739,282 (+)NCBI
Celera912,100,043 - 12,166,064 (+)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ptk7Ratinfantile Refsum disease  ISOPTK7 (Homo sapiens)8554872ClinVar Annotator: match by term: ADRENOLEUKODYSTROPHY and AUTOSOMAL NEONATALClinVarPMID:19877282 more ...
Ptk7RatZellweger syndrome  ISOPTK7 (Homo sapiens)8554872ClinVar Annotator: match by term: Peroxisome biogenesis disorders and Zellweger syndrome spectrumClinVarPMID:19877282 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ptk7RatNeurodevelopmental Disorders  ISOPTK7 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:28191889

1 to 20 of 78 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ptk7Rat1,2-dimethylhydrazine increases expressionISOPtk7 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of PTK7 mRNACTDPMID:22206623
Ptk7Rat1,2-dimethylhydrazine multiple interactionsISOPtk7 (Mus musculus)6480464Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of PTK7 mRNA]CTDPMID:22206623
Ptk7Rat1,3-dinitrobenzene increases expressionEXP 64804643-dinitrobenzene results in increased expression of PTK7 mRNACTDPMID:21983209
Ptk7Rat1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of PTK7 mRNACTDPMID:30723492
Ptk7Rat17beta-estradiol multiple interactionsISOPTK7 (Homo sapiens)6480464[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PTK7 mRNACTDPMID:20823114
Ptk7Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of PTK7 mRNACTDPMID:22298810
Ptk7Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPtk7 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of PTK7 mRNACTDPMID:26377647
Ptk7Rat2-bromohexadecanoic acid multiple interactionsISOPTK7 (Homo sapiens)64804642-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of PTK7 protein]CTDPMID:38195004
Ptk7Rat4,4'-diaminodiphenylmethane increases expressionISOPtk7 (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in increased expression of PTK7 mRNACTDPMID:18648102
Ptk7Rat4,4'-sulfonyldiphenol increases expressionISOPtk7 (Mus musculus)6480464bisphenol S results in increased expression of PTK7 mRNACTDPMID:39298647
Ptk7Rat4,4'-sulfonyldiphenol affects methylationISOPtk7 (Mus musculus)6480464bisphenol S affects the methylation of PTK7 geneCTDPMID:31683443
Ptk7Rat4,4'-sulfonyldiphenol decreases methylationISOPtk7 (Mus musculus)6480464bisphenol S results in decreased methylation of PTK7 exonCTDPMID:33297965
Ptk7Rat4-hydroxyphenyl retinamide increases expressionISOPtk7 (Mus musculus)6480464Fenretinide results in increased expression of PTK7 mRNACTDPMID:28973697
Ptk7Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of PTK7 mRNACTDPMID:24780913
Ptk7Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of PTK7 mRNACTDPMID:31881176
Ptk7Ratacrylamide decreases expressionISOPTK7 (Homo sapiens)6480464Acrylamide results in decreased expression of PTK7 mRNACTDPMID:32763439
Ptk7Rataflatoxin B1 increases expressionEXP 6480464Aflatoxin B1 results in increased expression of PTK7 mRNACTDPMID:25378103
Ptk7Rataflatoxin B1 decreases methylationISOPTK7 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of PTK7 intronCTDPMID:30157460
Ptk7RatAflatoxin B2 alpha decreases methylationISOPTK7 (Homo sapiens)6480464aflatoxin B2 results in decreased methylation of PTK7 intronCTDPMID:30157460
Ptk7Ratall-trans-retinoic acid increases expressionISOPTK7 (Homo sapiens)6480464Tretinoin results in increased expression of PTK7 mRNACTDPMID:23830798

1 to 20 of 78 rows

Biological Process
1 to 20 of 35 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ptk7Ratactin cytoskeleton organization involved_inISOPTK7 (Homo sapiens)1624291 PMID:20837484RGDPMID:20837484
Ptk7Ratactin cytoskeleton organization involved_inIEAUniProtKB:Q13308 and ensembl:ENSP000002304191600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Rataxis elongation acts_upstream_of_or_withinISOPtk7 (Mus musculus)1624291MGI:3640803 PMID:20704721RGDPMID:20704721
Ptk7Rataxis elongation acts_upstream_of_or_withinIEAUniProtKB:Q8BKG3 and ensembl:ENSMUSP000000437031600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Ratcell migration involved_inISOPTK7 (Homo sapiens)1624291 PMID:20837484RGDPMID:20837484
Ptk7Ratcell migration involved_inIEAUniProtKB:Q13308 and ensembl:ENSP000002304191600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Ratcellular response to retinoic acid involved_inISOPTK7 (Homo sapiens)1624291 PMID:17910947RGDPMID:17910947
Ptk7Ratcellular response to retinoic acid involved_inIEAUniProtKB:Q13308 and ensembl:ENSP000002304191600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Ratcochlea morphogenesis acts_upstream_of_or_withinISOPtk7 (Mus musculus)1624291MGI:3640803 PMID:20704721RGDPMID:20704721
Ptk7Ratcochlea morphogenesis acts_upstream_of_or_withinIEAUniProtKB:Q8BKG3 and ensembl:ENSMUSP000000437031600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Ratconvergent extension acts_upstream_of_or_withinISOPtk7 (Mus musculus)1624291MGI:3640803 PMID:20704721RGDPMID:20704721
Ptk7Ratconvergent extension acts_upstream_of_or_withinIEAUniProtKB:Q8BKG3 and ensembl:ENSMUSP000000437031600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Ratcoronary vasculature development acts_upstream_of_or_withinISOPtk7 (Mus musculus)1624291 PMID:25807483RGDPMID:25807483
Ptk7Ratcoronary vasculature development acts_upstream_of_or_withinIEAUniProtKB:Q8BKG3 and ensembl:ENSMUSP000000437031600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Ratestablishment of epithelial cell apical/basal polarity acts_upstream_of_or_withinISOPtk7 (Mus musculus)1624291MGI:3046905 PMID:15229603RGDPMID:15229603
Ptk7Ratestablishment of epithelial cell apical/basal polarity acts_upstream_of_or_withinIEAUniProtKB:Q8BKG3 and ensembl:ENSMUSP000000437031600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Ratestablishment of planar polarity acts_upstream_of_or_withinISOPtk7 (Mus musculus)1624291MGI:3640803 PMID:20704721RGDPMID:20704721
Ptk7Ratestablishment of planar polarity acts_upstream_of_or_withinIEAUniProtKB:Q8BKG3 and ensembl:ENSMUSP000000437031600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Ratheart development acts_upstream_of_or_withinISOPtk7 (Mus musculus)1624291 PMID:25807483RGDPMID:25807483
Ptk7Ratheart development acts_upstream_of_or_withinIEAUniProtKB:Q8BKG3 and ensembl:ENSMUSP000000437031600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 20 of 35 rows

Cellular Component
1 to 17 of 17 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ptk7Ratcell-cell junction located_inISOPTK7 (Homo sapiens)1624291 PMID:20837484RGDPMID:20837484
Ptk7Ratcell-cell junction located_inISOPtk7 (Mus musculus)1624291 PMID:20215345RGDPMID:20215345
Ptk7Ratcell-cell junction located_inIEAUniProtKB:Q8BKG3 and ensembl:ENSMUSP000000437031600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Ratcell-cell junction located_inIEAUniProtKB:Q13308 and ensembl:ENSP000002304191600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Ratcytosol located_inIEAUniProtKB:Q13308 and ensembl:ENSP000002304191600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Ratcytosol located_inISOPTK7 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Ptk7Ratintracellular membrane-bounded organelle located_inISOPTK7 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Ptk7Ratintracellular membrane-bounded organelle located_inIEAUniProtKB:Q13308 and ensembl:ENSP000002304191600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Ptk7Ratmembrane located_inIEAUniProtKB:Q8BKG3 and ensembl:ENSMUSP000000437031600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Ratmembrane located_inISOPtk7 (Mus musculus)1624291 PMID:20704721RGDPMID:20704721
Ptk7Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Ptk7Ratplasma membrane is_active_inIBAFB:FBgn0000017 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ptk7Ratplasma membrane located_inIEAUniProtKB:Q13308 and ensembl:ENSP000002304191600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Ratplasma membrane located_inIEAUniProtKB:Q8BKG3 and ensembl:ENSMUSP000000437031600115GO_REF:0000107EnsemblGO_REF:0000107
Ptk7Ratplasma membrane located_inISOPtk7 (Mus musculus)1624291 PMID:20215345RGDPMID:20215345
Ptk7Ratplasma membrane located_inISOPTK7 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
1 to 17 of 17 rows

Molecular Function

  

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ptk7RatWnt signaling, the planar cell polarity pathway   ISOPtk7 (Mus musculus)2293492 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Planar cell polarity signaling in vertebrates. Jones C and Chen P, Bioessays. 2007 Feb;29(2):120-32.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:15019986   PMID:15229603   PMID:15802564   PMID:17910947   PMID:20215345   PMID:20643356   PMID:20704721   PMID:20837484   PMID:21132015   PMID:21423176   PMID:25807483  



Ptk7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8921,849,756 - 21,916,077 (+)NCBIGRCr8
mRatBN7.2914,352,155 - 14,418,473 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl914,351,202 - 14,418,494 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx922,936,018 - 23,002,174 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0927,998,899 - 28,065,207 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0926,299,393 - 26,365,553 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0916,662,588 - 16,729,888 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl916,702,460 - 16,729,030 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0915,569,249 - 15,634,907 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.199,683,466 - 9,739,282 (+)NCBI
Celera912,100,043 - 12,166,064 (+)NCBICelera
Cytogenetic Map9q12NCBI
PTK7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38643,076,314 - 43,161,715 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl643,076,307 - 43,161,719 (+)EnsemblGRCh38hg38GRCh38
GRCh37643,044,052 - 43,129,453 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36643,152,007 - 43,237,435 (+)NCBINCBI36Build 36hg18NCBI36
Build 34643,152,006 - 43,237,435NCBI
Celera644,596,273 - 44,681,681 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef642,760,999 - 42,846,114 (+)NCBIHuRef
CHM1_1643,046,463 - 43,132,349 (+)NCBICHM1_1
T2T-CHM13v2.0642,905,060 - 42,990,493 (+)NCBIT2T-CHM13v2.0
Ptk7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391746,875,377 - 46,940,975 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1746,875,397 - 46,940,430 (-)EnsemblGRCm39 Ensembl
GRCm381746,564,451 - 46,630,049 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1746,564,471 - 46,629,504 (-)EnsemblGRCm38mm10GRCm38
MGSCv371746,701,400 - 46,766,453 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361746,027,640 - 46,092,625 (-)NCBIMGSCv36mm8
Celera1750,000,320 - 50,065,330 (-)NCBICelera
Cytogenetic Map17CNCBI
cM Map1722.9NCBI
Ptk7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554379,037,661 - 9,094,287 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554379,037,933 - 9,094,237 (+)NCBIChiLan1.0ChiLan1.0
PTK7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2557,575,885 - 57,661,691 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1653,446,156 - 53,532,268 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0642,668,077 - 42,753,547 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1643,962,566 - 44,047,346 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl643,962,560 - 44,051,146 (+)Ensemblpanpan1.1panPan2
PTK7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11211,593,017 - 11,657,149 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1211,593,043 - 11,656,320 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1211,620,045 - 11,684,140 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01212,074,382 - 12,139,509 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1212,074,376 - 12,139,507 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11211,603,020 - 11,667,064 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01211,687,299 - 11,751,491 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01211,781,164 - 11,846,279 (+)NCBIUU_Cfam_GSD_1.0
Ptk7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494647,093,213 - 47,162,366 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647616,798,686 - 16,866,896 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647616,797,836 - 16,866,989 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTK7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl738,135,655 - 38,205,655 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1738,135,675 - 38,205,662 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2743,636,042 - 43,706,031 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTK7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11729,001,797 - 29,083,767 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1729,001,805 - 29,083,700 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604443,139,028 - 43,220,861 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptk7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475416,386,296 - 16,440,681 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475416,386,437 - 16,441,341 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Ptk7
398 total Variants

Predicted Target Of
Summary Value
Count of predictions:68
Count of miRNA genes:61
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000061432
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 18 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat

1 to 10 of 18 rows
RH127795  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2914,350,702 - 14,350,904 (+)MAPPERmRatBN7.2
Rnor_6.0916,661,091 - 16,661,292NCBIRnor6.0
Rnor_5.0915,567,706 - 15,567,907UniSTSRnor5.0
RGSC_v3.4910,002,362 - 10,002,563UniSTSRGSC3.4
Celera912,098,500 - 12,098,701UniSTS
RH 3.4 Map958.3UniSTS
Cytogenetic Map9q12UniSTS
RH132300  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2914,371,237 - 14,371,431 (+)MAPPERmRatBN7.2
Rnor_6.0916,681,627 - 16,681,820NCBIRnor6.0
Rnor_5.0915,588,242 - 15,588,435UniSTSRnor5.0
RGSC_v3.499,981,536 - 9,981,729UniSTSRGSC3.4
Celera912,119,008 - 12,119,201UniSTS
RH 3.4 Map955.0UniSTS
Cytogenetic Map9q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000061432   ⟹   ENSRNOP00000058151
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl914,391,806 - 14,418,494 (+)Ensembl
Rnor_6.0 Ensembl916,702,460 - 16,729,030 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108486   ⟹   ENSRNOP00000094298
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl914,352,254 - 14,418,469 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113952   ⟹   ENSRNOP00000097123
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl914,351,202 - 14,392,416 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118183   ⟹   ENSRNOP00000094722
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl914,352,800 - 14,418,469 (+)Ensembl
RefSeq Acc Id: NM_001395741   ⟹   NP_001382670
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8921,849,756 - 21,916,077 (+)NCBI
mRatBN7.2914,352,155 - 14,418,473 (+)NCBI
Protein RefSeqs NP_001382670 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM18829 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000058151.5
  ENSRNOP00000094298
  ENSRNOP00000094298.1
  ENSRNOP00000094722.1
  ENSRNOP00000097123.1
Ensembl Acc Id: ENSRNOP00000058151   ⟸   ENSRNOT00000061432
Ensembl Acc Id: ENSRNOP00000094722   ⟸   ENSRNOT00000118183
Ensembl Acc Id: ENSRNOP00000097123   ⟸   ENSRNOT00000113952
Ensembl Acc Id: ENSRNOP00000094298   ⟸   ENSRNOT00000108486
RefSeq Acc Id: NP_001382670   ⟸   NM_001395741
- Peptide Label: precursor
- UniProtKB: A0A8I6AKN3 (UniProtKB/TrEMBL),   A0A8I6ALM9 (UniProtKB/TrEMBL)
Ig-like   Protein kinase

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZHG3-F1-model_v2 AlphaFold D3ZHG3 1-778 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 40 of 45 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-28233 BioCyc
Ensembl Genes ENSRNOG00000039976 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000061432.5 UniProtKB/TrEMBL
  ENSRNOT00000108486 ENTREZGENE
  ENSRNOT00000108486.1 UniProtKB/TrEMBL
  ENSRNOT00000113952.1 UniProtKB/TrEMBL
  ENSRNOT00000118183.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Cell_Adh-Cytoskel_Orgn UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Striated_Muscle_Regulatory UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
NCBI Gene 301242 ENTREZGENE
PANTHER CONTACTIN 5 UniProtKB/TrEMBL
  INACTIVE TYROSINE-PROTEIN KINASE 7 UniProtKB/TrEMBL
  TITIN UniProtKB/TrEMBL
  ZORMIN, ISOFORM J UniProtKB/TrEMBL
Pfam I-set UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/TrEMBL
PharmGKB PTK7 RGD
PhenoGen Ptk7 PhenoGen
PRINTS TYRKINASE UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000039976 RatGTEx
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
1 to 40 of 45 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-03-26 Ptk7  protein tyrosine kinase 7  Ptk7  PTK7 protein tyrosine kinase 7  Name changed 629549 APPROVED
2008-04-30 Ptk7  PTK7 protein tyrosine kinase 7   Ptk7_predicted  PTK7 protein tyrosine kinase 7 (predicted)  'predicted' is removed 2292626 APPROVED
2006-08-22 Ptk7_predicted  PTK7 protein tyrosine kinase 7 (predicted)  Srf_predicted  serum response factor (predicted)  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2005-01-12 Srf_predicted  serum response factor (predicted)      Symbol and Name status set to approved 70820 APPROVED