PTK7 (protein tyrosine kinase 7 (inactive)) - Rat Genome Database

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Gene: PTK7 (protein tyrosine kinase 7 (inactive)) Pan paniscus
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Symbol: PTK7
Name: protein tyrosine kinase 7 (inactive)
RGD ID: 11795532
Description: ENCODES a protein that exhibits kinase activity (ortholog); transmembrane receptor protein tyrosine kinase activity (ortholog); INVOLVED IN axis elongation (ortholog); cochlea morphogenesis (ortholog); convergent extension (ortholog); PARTICIPATES IN Wnt signaling, the planar cell polarity pathway; ASSOCIATED WITH infantile Refsum disease (ortholog); Neurodevelopmental Disorders (ortholog); Zellweger syndrome (ortholog); FOUND IN axon (inferred); cell-cell junction (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inactive tyrosine-protein kinase 7; PTK7 protein tyrosine kinase 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2557,575,885 - 57,661,691 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1653,446,156 - 53,532,268 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0642,668,077 - 42,753,547 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1643,962,566 - 44,047,346 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl643,962,560 - 44,051,146 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PTK7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2557,575,885 - 57,661,691 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1653,446,156 - 53,532,268 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0642,668,077 - 42,753,547 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1643,962,566 - 44,047,346 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl643,962,560 - 44,051,146 (+)Ensemblpanpan1.1panPan2
PTK7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38643,076,314 - 43,161,715 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl643,076,307 - 43,161,719 (+)EnsemblGRCh38hg38GRCh38
GRCh37643,044,052 - 43,129,453 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36643,152,007 - 43,237,435 (+)NCBINCBI36Build 36hg18NCBI36
Build 34643,152,006 - 43,237,435NCBI
Celera644,596,273 - 44,681,681 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef642,760,999 - 42,846,114 (+)NCBIHuRef
CHM1_1643,046,463 - 43,132,349 (+)NCBICHM1_1
T2T-CHM13v2.0642,905,060 - 42,990,493 (+)NCBIT2T-CHM13v2.0
Ptk7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391746,875,377 - 46,940,975 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1746,875,397 - 46,940,430 (-)EnsemblGRCm39 Ensembl
GRCm381746,564,451 - 46,630,049 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1746,564,471 - 46,629,504 (-)EnsemblGRCm38mm10GRCm38
MGSCv371746,701,400 - 46,766,453 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361746,027,640 - 46,092,625 (-)NCBIMGSCv36mm8
Celera1750,000,320 - 50,065,330 (-)NCBICelera
Cytogenetic Map17CNCBI
cM Map1722.9NCBI
Ptk7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8921,849,756 - 21,916,077 (+)NCBIGRCr8
mRatBN7.2914,352,155 - 14,418,473 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl914,351,202 - 14,418,494 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx922,936,018 - 23,002,174 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0927,998,899 - 28,065,207 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0926,299,393 - 26,365,553 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0916,662,588 - 16,729,888 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl916,702,460 - 16,729,030 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0915,569,249 - 15,634,907 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.199,683,466 - 9,739,282 (+)NCBI
Celera912,100,043 - 12,166,064 (+)NCBICelera
Cytogenetic Map9q12NCBI
Ptk7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554379,037,661 - 9,094,287 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554379,037,933 - 9,094,237 (+)NCBIChiLan1.0ChiLan1.0
PTK7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11211,593,017 - 11,657,149 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1211,593,043 - 11,656,320 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1211,620,045 - 11,684,140 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01212,074,382 - 12,139,509 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1212,074,376 - 12,139,507 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11211,603,020 - 11,667,064 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01211,687,299 - 11,751,491 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01211,781,164 - 11,846,279 (+)NCBIUU_Cfam_GSD_1.0
Ptk7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494647,093,213 - 47,162,366 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647616,798,686 - 16,866,896 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647616,797,836 - 16,866,989 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTK7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl738,135,655 - 38,205,655 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1738,135,675 - 38,205,662 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2743,636,042 - 43,706,031 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTK7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11729,001,797 - 29,083,767 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1729,001,805 - 29,083,700 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604443,139,028 - 43,220,861 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptk7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475416,386,296 - 16,440,681 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475416,386,437 - 16,441,341 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000056190   ⟹   ENSPPAP00000033315
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl643,962,560 - 44,051,146 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000056200   ⟹   ENSPPAP00000033325
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl643,962,560 - 44,051,146 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000056225   ⟹   ENSPPAP00000033350
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl643,962,620 - 44,046,511 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000056229   ⟹   ENSPPAP00000033354
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl643,962,620 - 44,046,511 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000056230   ⟹   ENSPPAP00000033355
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl643,962,620 - 44,046,511 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000056231   ⟹   ENSPPAP00000033356
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl643,963,015 - 44,046,511 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000056233   ⟹   ENSPPAP00000033358
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl644,010,696 - 44,046,511 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000056234   ⟹   ENSPPAP00000033359
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl644,013,151 - 44,046,511 (+)Ensembl
RefSeq Acc Id: XM_003833267   ⟹   XP_003833315
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2557,575,885 - 57,661,691 (+)NCBI
NHGRI_mPanPan1653,446,156 - 53,532,266 (+)NCBI
Mhudiblu_PPA_v0642,668,077 - 42,753,547 (+)NCBI
PanPan1.1643,962,566 - 44,047,346 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034962115   ⟹   XP_034818006
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2557,576,397 - 57,661,691 (+)NCBI
NHGRI_mPanPan1653,446,682 - 53,532,267 (+)NCBI
Mhudiblu_PPA_v0642,668,581 - 42,753,547 (+)NCBI
RefSeq Acc Id: XM_034962116   ⟹   XP_034818007
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2557,616,160 - 57,661,691 (+)NCBI
NHGRI_mPanPan1653,486,521 - 53,532,267 (+)NCBI
Mhudiblu_PPA_v0642,708,380 - 42,753,547 (+)NCBI
RefSeq Acc Id: XM_055113624   ⟹   XP_054969599
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2557,575,885 - 57,661,691 (+)NCBI
NHGRI_mPanPan1653,446,169 - 53,532,268 (+)NCBI
RefSeq Acc Id: XP_003833315   ⟸   XM_003833267
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BUK4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034818006   ⟸   XM_034962115
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BV68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034818007   ⟸   XM_034962116
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C473 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000033315   ⟸   ENSPPAT00000056190
Ensembl Acc Id: ENSPPAP00000033354   ⟸   ENSPPAT00000056229
Ensembl Acc Id: ENSPPAP00000033350   ⟸   ENSPPAT00000056225
Ensembl Acc Id: ENSPPAP00000033355   ⟸   ENSPPAT00000056230
Ensembl Acc Id: ENSPPAP00000033356   ⟸   ENSPPAT00000056231
Ensembl Acc Id: ENSPPAP00000033359   ⟸   ENSPPAT00000056234
Ensembl Acc Id: ENSPPAP00000033358   ⟸   ENSPPAT00000056233
Ensembl Acc Id: ENSPPAP00000033325   ⟸   ENSPPAT00000056200
RefSeq Acc Id: XP_054969599   ⟸   XM_055113624
- Peptide Label: isoform X4
- UniProtKB: A0A2R9C468 (UniProtKB/TrEMBL)
Protein Domains
Ig-like   Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039415 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000056190.1 UniProtKB/TrEMBL
  ENSPPAT00000056200.1 UniProtKB/TrEMBL
  ENSPPAT00000056225.1 UniProtKB/TrEMBL
  ENSPPAT00000056229.1 UniProtKB/TrEMBL
  ENSPPAT00000056230.1 UniProtKB/TrEMBL
  ENSPPAT00000056231.1 UniProtKB/TrEMBL
  ENSPPAT00000056233.1 UniProtKB/TrEMBL
  ENSPPAT00000056234.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Cell_Adh-Cytoskel_Orgn UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
KEGG Report pps:100988693 UniProtKB/TrEMBL
NCBI Gene PTK7 ENTREZGENE
PANTHER CONTACTIN 5 UniProtKB/TrEMBL
  INACTIVE TYROSINE-PROTEIN KINASE 7 UniProtKB/TrEMBL
Pfam I-set UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
  PK_Tyr_Ser-Thr UniProtKB/TrEMBL
PIRSF TyrPK_CSF1-R UniProtKB/TrEMBL
PRINTS TYRKINASE UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A2R9BUK4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BV68 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BXV6_PANPA UniProtKB/TrEMBL
  A0A2R9BXW9_PANPA UniProtKB/TrEMBL
  A0A2R9BXZ2_PANPA UniProtKB/TrEMBL
  A0A2R9BXZ9_PANPA UniProtKB/TrEMBL
  A0A2R9C468 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C473 ENTREZGENE, UniProtKB/TrEMBL