PTK7 (protein tyrosine kinase 7 (inactive)) - Rat Genome Database

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Gene: PTK7 (protein tyrosine kinase 7 (inactive)) Chlorocebus sabaeus
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Symbol: PTK7
Name: protein tyrosine kinase 7 (inactive)
RGD ID: 18373928
Description: ENCODES a protein that exhibits kinase activity (ortholog); transmembrane receptor protein tyrosine kinase activity (ortholog); INVOLVED IN axis elongation (ortholog); cochlea morphogenesis (ortholog); convergent extension (ortholog); PARTICIPATES IN Wnt signaling, the planar cell polarity pathway; ASSOCIATED WITH infantile Refsum disease (ortholog); Neurodevelopmental Disorders (ortholog); Zellweger syndrome (ortholog); FOUND IN axon (inferred); cell-cell junction (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inactive tyrosine-protein kinase 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11729,001,797 - 29,083,767 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1729,001,805 - 29,083,700 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604443,139,028 - 43,220,861 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PTK7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11729,001,797 - 29,083,767 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1729,001,805 - 29,083,700 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604443,139,028 - 43,220,861 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PTK7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38643,076,314 - 43,161,715 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl643,076,307 - 43,161,719 (+)EnsemblGRCh38hg38GRCh38
GRCh37643,044,052 - 43,129,453 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36643,152,007 - 43,237,435 (+)NCBINCBI36Build 36hg18NCBI36
Build 34643,152,006 - 43,237,435NCBI
Celera644,596,273 - 44,681,681 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef642,760,999 - 42,846,114 (+)NCBIHuRef
CHM1_1643,046,463 - 43,132,349 (+)NCBICHM1_1
T2T-CHM13v2.0642,905,060 - 42,990,493 (+)NCBIT2T-CHM13v2.0
Ptk7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391746,875,377 - 46,940,975 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1746,875,397 - 46,940,430 (-)EnsemblGRCm39 Ensembl
GRCm381746,564,451 - 46,630,049 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1746,564,471 - 46,629,504 (-)EnsemblGRCm38mm10GRCm38
MGSCv371746,701,400 - 46,766,453 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361746,027,640 - 46,092,625 (-)NCBIMGSCv36mm8
Celera1750,000,320 - 50,065,330 (-)NCBICelera
Cytogenetic Map17CNCBI
cM Map1722.9NCBI
Ptk7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8921,849,756 - 21,916,077 (+)NCBIGRCr8
mRatBN7.2914,352,155 - 14,418,473 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl914,351,202 - 14,418,494 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx922,936,018 - 23,002,174 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0927,998,899 - 28,065,207 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0926,299,393 - 26,365,553 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0916,662,588 - 16,729,888 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl916,702,460 - 16,729,030 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0915,569,249 - 15,634,907 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.199,683,466 - 9,739,282 (+)NCBI
Celera912,100,043 - 12,166,064 (+)NCBICelera
Cytogenetic Map9q12NCBI
Ptk7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554379,037,661 - 9,094,287 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554379,037,933 - 9,094,237 (+)NCBIChiLan1.0ChiLan1.0
PTK7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2557,575,885 - 57,661,691 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1653,446,156 - 53,532,268 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0642,668,077 - 42,753,547 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1643,962,566 - 44,047,346 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl643,962,560 - 44,051,146 (+)Ensemblpanpan1.1panPan2
PTK7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11211,593,017 - 11,657,149 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1211,593,043 - 11,656,320 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1211,620,045 - 11,684,140 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01212,074,382 - 12,139,509 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1212,074,376 - 12,139,507 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11211,603,020 - 11,667,064 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01211,687,299 - 11,751,491 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01211,781,164 - 11,846,279 (+)NCBIUU_Cfam_GSD_1.0
Ptk7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494647,093,213 - 47,162,366 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647616,798,686 - 16,866,896 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647616,797,836 - 16,866,989 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTK7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl738,135,655 - 38,205,655 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1738,135,675 - 38,205,662 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2743,636,042 - 43,706,031 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Ptk7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475416,386,296 - 16,440,681 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475416,386,437 - 16,441,341 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000009702   ⟹   ENSCSAP00000007812
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1729,001,805 - 29,083,700 (-)Ensembl
RefSeq Acc Id: XM_007972503   ⟹   XP_007970694
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11729,001,797 - 29,083,767 (-)NCBI
Vero_WHO_p1.0NW_02366604443,139,028 - 43,220,861 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007972504   ⟹   XP_007970695
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11729,001,797 - 29,082,786 (-)NCBI
Vero_WHO_p1.0NW_02366604443,139,994 - 43,220,861 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007972505   ⟹   XP_007970696
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11729,001,797 - 29,083,767 (-)NCBI
Vero_WHO_p1.0NW_02366604443,139,028 - 43,220,861 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007970694 (Get FASTA)   NCBI Sequence Viewer  
  XP_007970695 (Get FASTA)   NCBI Sequence Viewer  
  XP_007970696 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007812
  ENSCSAP00000007812.1
RefSeq Acc Id: XP_007970696   ⟸   XM_007972505
- Peptide Label: isoform X3
RefSeq Acc Id: XP_007970694   ⟸   XM_007972503
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RGS3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007970695   ⟸   XM_007972504
- Peptide Label: isoform X2
Ensembl Acc Id: ENSCSAP00000007812   ⟸   ENSCSAT00000009702


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011617 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009702.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Cell_Adh-Cytoskel_Orgn UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
KEGG Report csab:103221474 UniProtKB/TrEMBL
NCBI Gene PTK7 ENTREZGENE
PANTHER CONTACTIN 5 UniProtKB/TrEMBL
  INACTIVE TYROSINE-PROTEIN KINASE 7 UniProtKB/TrEMBL
Pfam I-set UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/TrEMBL
PRINTS TYRKINASE UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A0D9RGS3 ENTREZGENE, UniProtKB/TrEMBL