Adgrf5 (adhesion G protein-coupled receptor F5) - Rat Genome Database

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Gene: Adgrf5 (adhesion G protein-coupled receptor F5) Rattus norvegicus
Analyze
Symbol: Adgrf5
Name: adhesion G protein-coupled receptor F5
RGD ID: 621679
Description: Predicted to have G protein-coupled receptor activity. Predicted to be involved in several processes, including glomerular filtration; pharyngeal arch artery morphogenesis; and surfactant homeostasis. Predicted to localize to apical part of cell; cell surface; and cytoplasmic vesicle. Orthologous to human ADGRF5 (adhesion G protein-coupled receptor F5); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: G protein-coupled hepta-helical receptor Ig-Hepta; G protein-coupled receptor 116; G-protein coupled hepta-helical receptor Ig-hepta; G-protein coupled receptor 116; Gpr116; Gprhep; Ig-Hepta; probable G-protein coupled receptor 116
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2917,517,596 - 17,624,107 (-)NCBI
Rnor_6.0 Ensembl920,091,099 - 20,195,566 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0920,091,121 - 20,195,706 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0918,967,333 - 19,071,668 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4913,217,956 - 13,323,415 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1913,215,277 - 13,320,737 (-)NCBI
Celera915,237,160 - 15,339,123 (-)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:11973329   PMID:22971422   PMID:23590306   PMID:23684610   PMID:25778400   PMID:28806758  


Genomics

Comparative Map Data
Adgrf5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2917,517,596 - 17,624,107 (-)NCBI
Rnor_6.0 Ensembl920,091,099 - 20,195,566 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0920,091,121 - 20,195,706 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0918,967,333 - 19,071,668 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4913,217,956 - 13,323,415 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1913,215,277 - 13,320,737 (-)NCBI
Celera915,237,160 - 15,339,123 (-)NCBICelera
Cytogenetic Map9q13NCBI
ADGRF5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl646,852,522 - 46,954,943 (-)EnsemblGRCh38hg38GRCh38
GRCh38646,852,522 - 46,954,954 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37646,820,259 - 46,922,676 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36646,928,201 - 47,030,634 (-)NCBINCBI36hg18NCBI36
Build 34646,928,297 - 46,990,825NCBI
Celera648,372,598 - 48,475,024 (-)NCBI
Cytogenetic Map6p12.3NCBI
HuRef646,543,478 - 46,645,785 (-)NCBIHuRef
CHM1_1646,823,487 - 46,925,912 (-)NCBICHM1_1
Adgrf5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391743,671,224 - 43,770,448 (+)NCBIGRCm39mm39
GRCm39 Ensembl1743,671,342 - 43,770,448 (+)Ensembl
GRCm381743,360,329 - 43,459,557 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1743,360,451 - 43,459,557 (+)EnsemblGRCm38mm10GRCm38
MGSCv371743,526,415 - 43,596,506 (+)NCBIGRCm37mm9NCBIm37
MGSCv361742,825,075 - 42,924,198 (+)NCBImm8
Celera1746,814,258 - 46,884,453 (+)NCBICelera
Cytogenetic Map17B3NCBI
Adgrf5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543711,639,891 - 11,688,257 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543711,639,555 - 11,710,362 (-)NCBIChiLan1.0ChiLan1.0
ADGRF5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1647,703,158 - 47,805,347 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl647,700,570 - 47,772,510 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0646,438,128 - 46,540,325 (-)NCBIMhudiblu_PPA_v0panPan3
ADGRF5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11215,013,567 - 15,115,889 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1215,006,949 - 15,086,116 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1215,045,001 - 15,147,394 (-)NCBI
ROS_Cfam_1.01215,510,094 - 15,612,365 (-)NCBI
UMICH_Zoey_3.11215,024,852 - 15,127,029 (-)NCBI
UNSW_CanFamBas_1.01215,117,916 - 15,219,946 (-)NCBI
UU_Cfam_GSD_1.01215,263,867 - 15,336,692 (-)NCBI
Adgrf5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494650,457,310 - 50,546,121 (-)NCBI
SpeTri2.0NW_00493647613,414,087 - 13,503,926 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADGRF5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl741,640,258 - 41,769,286 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1741,640,256 - 41,769,422 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2748,301,437 - 48,429,345 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADGRF5
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11725,323,613 - 25,427,370 (+)NCBI
ChlSab1.1 Ensembl1725,356,427 - 25,430,061 (+)Ensembl
Vero_WHO_p1.0NW_02366604446,866,043 - 46,976,173 (-)NCBI
Adgrf5
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475413,778,573 - 13,843,931 (+)NCBI

Position Markers
D9Got26  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2917,584,551 - 17,584,707 (+)MAPPER
Rnor_6.0920,156,566 - 20,156,721NCBIRnor6.0
Rnor_5.0919,032,778 - 19,032,933UniSTSRnor5.0
RGSC_v3.4913,283,515 - 13,283,671RGDRGSC3.4
RGSC_v3.4913,283,516 - 13,283,671UniSTSRGSC3.4
RGSC_v3.1913,280,838 - 13,280,993RGD
Celera915,300,501 - 15,300,656UniSTS
RH 3.4 Map9125.9UniSTS
RH 3.4 Map9125.9RGD
RH 2.0 Map90.0RGD
Cytogenetic Map9q12UniSTS
D9Got23  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2917,565,176 - 17,565,422 (+)MAPPER
Rnor_6.0920,138,702 - 20,138,947NCBIRnor6.0
Rnor_5.0919,014,914 - 19,015,159UniSTSRnor5.0
RGSC_v3.4913,262,121 - 13,262,367RGDRGSC3.4
RGSC_v3.4913,262,122 - 13,262,367UniSTSRGSC3.4
RGSC_v3.1913,259,444 - 13,259,689RGD
Celera915,281,341 - 15,281,588UniSTS
RH 3.4 Map9105.3UniSTS
RH 3.4 Map9105.3RGD
RH 2.0 Map999.8RGD
Cytogenetic Map9q12UniSTS
D9Wox36  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2917,521,251 - 17,521,491 (+)MAPPER
Rnor_6.0920,094,776 - 20,095,015NCBIRnor6.0
Rnor_5.0918,970,988 - 18,971,227UniSTSRnor5.0
RGSC_v3.4913,218,196 - 13,218,435UniSTSRGSC3.4
Celera915,237,400 - 15,237,639UniSTS
Cytogenetic Map9q12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9129467098Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9140383872Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9140383872Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9140383872Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9145029794Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9105522293442944Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9235572247355722Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9235572247355722Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9288097747375681Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9288097747880977Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9498609549986095Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9498609549986095Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9572425425692342Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)91221677157216771Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)91242546357425463Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)91242546357425463Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91555490147249201Rat
724543Cm20Cardiac mass QTL 203.9heart mass (VT:0007028)calculated heart weight (CMO:0000073)91952048945029794Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:50
Interacting mature miRNAs:51
Transcripts:ENSRNOT00000015223
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 35 25 14 14 14 8 10 35 35 27 11 8
Low 3 8 32 27 5 27 1 39 14
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000015223   ⟹   ENSRNOP00000015223
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl920,094,536 - 20,195,566 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000082904   ⟹   ENSRNOP00000071238
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl920,091,099 - 20,154,077 (-)Ensembl
RefSeq Acc Id: NM_139110   ⟹   NP_620810
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2917,521,012 - 17,623,968 (-)NCBI
Rnor_6.0920,094,536 - 20,195,566 (-)NCBI
Rnor_5.0918,967,333 - 19,071,668 (-)NCBI
RGSC_v3.4913,217,956 - 13,323,415 (-)RGD
Celera915,237,160 - 15,339,123 (-)RGD
Sequence:
RefSeq Acc Id: XM_006244594   ⟹   XP_006244656
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0920,091,121 - 20,168,002 (-)NCBI
Rnor_5.0918,967,333 - 19,071,668 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006244597   ⟹   XP_006244659
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0920,091,121 - 20,167,962 (-)NCBI
Rnor_5.0918,967,333 - 19,071,668 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008766832   ⟹   XP_008765054
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2917,517,596 - 17,595,904 (-)NCBI
Rnor_6.0920,091,121 - 20,168,004 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008766833   ⟹   XP_008765055
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2917,517,596 - 17,624,107 (-)NCBI
Rnor_6.0920,091,121 - 20,195,706 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008766834   ⟹   XP_008765056
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2917,521,671 - 17,582,066 (-)NCBI
Rnor_6.0920,095,245 - 20,168,006 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008766835   ⟹   XP_008765057
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0920,091,121 - 20,168,004 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083012   ⟹   XP_038938940
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2917,517,596 - 17,582,066 (-)NCBI
RefSeq Acc Id: XM_039083013   ⟹   XP_038938941
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2917,517,596 - 17,582,066 (-)NCBI
RefSeq Acc Id: XM_039083014   ⟹   XP_038938942
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2917,517,596 - 17,592,525 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_620810   ⟸   NM_139110
- Peptide Label: precursor
- UniProtKB: Q9WVT0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006244656   ⟸   XM_006244594
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006244659   ⟸   XM_006244597
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008765055   ⟸   XM_008766833
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008765054   ⟸   XM_008766832
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008765057   ⟸   XM_008766835
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008765056   ⟸   XM_008766834
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000071238   ⟸   ENSRNOT00000082904
RefSeq Acc Id: ENSRNOP00000015223   ⟸   ENSRNOT00000015223
RefSeq Acc Id: XP_038938942   ⟸   XM_039083014
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038938940   ⟸   XM_039083012
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038938941   ⟸   XM_039083013
- Peptide Label: isoform X3
Protein Domains
G_PROTEIN_RECEP_F2_4   GPS   Ig-like   SEA

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696558
Promoter ID:EPDNEW_R7082
Type:multiple initiation site
Name:Adgrf5_1
Description:adhesion G protein-coupled receptor F5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0920,195,601 - 20,195,661EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621679 AgrOrtholog
Ensembl Genes ENSRNOG00000011154 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000015223 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000071238 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015223 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000082904 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GAIN_dom_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_Ig-hepta-like_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_secretin-like_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEA_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:245977 UniProtKB/Swiss-Prot
NCBI Gene 245977 ENTREZGENE
Pfam 7tm_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00047 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Adgrf5 PhenoGen
PRINTS GPCRSECRETIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGHEPTARCPTR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF82671 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JZZ0_RAT UniProtKB/TrEMBL
  AGRF5_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-03-16 Adgrf5  adhesion G protein-coupled receptor F5  Gpr116  G protein-coupled receptor 116  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Gpr116  G protein-coupled receptor 116  Gprhep  G protein-coupled hepta-helical receptor Ig-Hepta  Symbol and Name updated 1299863 APPROVED
2004-02-11 Gprhep    Ig-Hepta  G protein-coupled hepta-helical receptor Ig-Hepta  Symbol updated to reflect Human and Mouse nomenclature 625702 APPROVED
2002-08-07 Ig-Hepta  G protein-coupled hepta-helical receptor Ig-Hepta      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains a long extracellular domain comprising Ig-like repeats 625424
gene_expression expressed predominantly in the lung 625424