Slc22a7 (solute carrier family 22 member 7)

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Gene: Slc22a7 (solute carrier family 22 member 7) Rattus norvegicus

Analyze

Symbol:

Slc22a7

Name:

solute carrier family 22 member 7

RGD ID:

621699

Description:

Exhibits organic anion transmembrane transporter activity. Involved in organic anion transport. Predicted to localize to basolateral plasma membrane. Orthologous to human SLC22A7 (solute carrier family 22 member 7); PARTICIPATES IN multispecific organic anion transporter mediated transport pathway; bile acid transport pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

novel liver transporter; Oat2; organic anion transporter 2; solute carrier family 22 (organic anion transporter), member 7

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC22A7 (solute carrier family 22 member 7)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Slc22a7 (solute carrier family 22 (organic anion transporter), member 7)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Slc22a7 (solute carrier family 22 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC22A7 (solute carrier family 22 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC22A7 (solute carrier family 22 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc22a7 (solute carrier family 22 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC22A7 (solute carrier family 22 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	SLC22A7 (solute carrier family 22 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc22a7 (solute carrier family 22 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SLC22A7 (solute carrier family 22 member 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Mus musculus (house mouse):	Slc22a7 (solute carrier family 22 (organic anion transporter), member 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	slc22a7b.1 (solute carrier family 22 member 7b, tandem duplicate 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|TreeFam)
Danio rerio (zebrafish):	slc22a7b.3 (solute carrier family 22 member 7b, tandem duplicate 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|TreeFam)
Danio rerio (zebrafish):	slc22a7a (solute carrier family 22 member 7a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	CG14691	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	CG15221	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	CG31103	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	CG31106	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	CG31272	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	GIT1	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Caenorhabditis elegans (roundworm):	F23F12.13	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Caenorhabditis elegans (roundworm):	F23F12.3	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	CG33233	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	CG33234	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	CG3690	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	CG12783	Alliance	DIOPT (Ensembl Compara\|PANTHER)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	9	16,925,321 - 16,931,119 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	16,924,520 - 16,931,766 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	15,822,368 - 15,828,166 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	9,934,309 - 9,940,107 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	9	9,931,570 - 9,937,643 (+)	NCBI
Celera	9	12,295,095 - 12,300,893 (+)	NCBI		Celera
Cytogenetic Map	9	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

1-naphthyl isothiocyanate (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (EXP,ISO)

2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-hexadecafluorononanoic acid (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol (EXP)

4-aminobenzoic acid (EXP,ISO)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

acetylsalicylic acid (ISO)

aflatoxin B1 (ISO)

allopurinol (ISO)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

benzoic acid (EXP,ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bosentan (ISO)

bromosulfophthalein (ISO)

bumetanide (ISO)

C60 fullerene (EXP)

carbamazepine (EXP)

carbon nanotube (ISO)

cefoperazone (ISO)

chenodeoxycholic acid (ISO)

chloramphenicol (ISO)

chlorpromazine (ISO)

choline (ISO)

cimetidine (ISO)

cinnamic acid (EXP,ISO)

cisplatin (ISO)

cyclosporin A (ISO)

dehydroepiandrosterone sulfate (ISO)

deoxycholic acid (ISO)

dexamethasone (EXP)

dichloroacetic acid (ISO)

diclofenac (ISO)

enalapril (ISO)

endosulfan (ISO)

erythromycin A (ISO)

estrone 3-sulfate (ISO)

felbamate (EXP)

flutamide (EXP)

folic acid (ISO)

furosemide (ISO)

gabapentin (EXP)

gamma-aminobutyric acid (ISO)

GW 501516 (ISO)

Heliotrine (ISO)

ibuprofen (ISO)

indocyanine green (ISO)

indometacin (ISO)

keto-phenylpyruvic acid (ISO)

ketoprofen (ISO)

L-ascorbic acid (ISO)

L-methionine (ISO)

mefenamic acid (ISO)

methotrexate (ISO)

methylmercury(1+) (EXP)

methyltestosterone (ISO)

microcystin-LR (ISO)

minocycline (ISO)

N-nitrosodiethylamine (EXP,ISO)

N-Nitrosopyrrolidine (ISO)

N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine (ISO)

naproxen (ISO)

nefazodone (EXP)

nicotinic acid (EXP,ISO)

O-methyleugenol (ISO)

ochratoxin A (EXP,ISO)

oltipraz (ISO)

orotic acid (EXP,ISO)

oxytetracycline (ISO)

p-aminohippuric acid (ISO)

paclitaxel (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (EXP)

perfluorooctanoic acid (EXP)

phenacetin (ISO)

phenobarbital (EXP,ISO)

phenylacetic acid (EXP)

phenytoin (EXP)

pirinixic acid (ISO)

piroxicam (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

propiconazole (ISO)

prostaglandin E2 (ISO)

prostaglandin F2alpha (ISO)

ranitidine (ISO)

resveratrol (ISO)

rifampicin (ISO)

rotenone (EXP)

salicylic acid (EXP,ISO)

senecionine (ISO)

Senkirkine (ISO)

sodium arsenite (ISO)

soybean oil (EXP)

sulfasalazine (ISO)

sulindac (ISO)

tamoxifen (ISO)

tebuconazole (ISO)

testosterone (EXP)

tetrachloroethene (ISO)

tetrachloromethane (EXP,ISO)

tetracycline (ISO)

thioacetamide (EXP)

trans-cinnamic acid (EXP,ISO)

trichloroethene (EXP,ISO)

Triptolide (EXP)

troglitazone (ISO)

urethane (ISO)

valproic acid (EXP,ISO)

vancomycin (ISO)

zidovudine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

organic anion transport (IDA,TAS)

response to stilbenoid (ISO)

transmembrane transport (IEA)

Cellular Component

basolateral plasma membrane (ISO)

integral component of plasma membrane (TAS)

plasma membrane (ISO)

Molecular Function

organic anion transmembrane transporter activity (IDA,ISO,TAS)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

bile acid transport pathway (IEA)

multispecific organic anion transporter mediated transport pathway (IDA)

References

References - curated


1.	Beery E, etal., Endocrinology 2003 Oct;144(10):4519-26. Epub 2003 Jun 26.
2.	Buist SC, etal., J Pharmacol Exp Ther 2002 Apr;301(1):145-51.
3.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	GOA data from the GO Consortium
5.	Kobayashi Y, etal., Biochem Biophys Res Commun 2002 Jan 11;290(1):482-7.
6.	MGD data from the GO Consortium
7.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	Pipeline to import KEGG annotations from KEGG into RGD
9.	RGD automated data pipeline
10.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	RGD automated import pipeline for gene-chemical interactions
12.	Sekine T, etal., FEBS Lett 1998 Jun 12;429(2):179-82.
13.	Simonson GD, etal., J Cell Sci 1994 Apr;107 ( Pt 4):1065-72.

Additional References at PubMed

PMID:12034823	PMID:16885152	PMID:17086191	PMID:17244698	PMID:21446918	PMID:25710042	PMID:25904762	PMID:27053689

Genomics

Comparative Map Data

Slc22a7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	9	16,925,321 - 16,931,119 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	16,924,520 - 16,931,766 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	15,822,368 - 15,828,166 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	9,934,309 - 9,940,107 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	9	9,931,570 - 9,937,643 (+)	NCBI
Celera	9	12,295,095 - 12,300,893 (+)	NCBI		Celera
Cytogenetic Map	9	q12	NCBI

SLC22A7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	6	43,295,694 - 43,305,538 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	6	43,295,710 - 43,305,538 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	6	43,265,737 - 43,273,276 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	43,373,976 - 43,381,254 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	6	43,373,979 - 43,381,252	NCBI
Celera	6	44,817,758 - 44,825,036 (+)	NCBI
Cytogenetic Map	6	p21.1	NCBI
HuRef	6	42,984,503 - 42,991,781 (+)	NCBI		HuRef
CHM1_1	6	43,268,944 - 43,276,222 (+)	NCBI		CHM1_1

Slc22a7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	46,743,111 - 46,749,403 (-)	NCBI	GRCm39		mm39
GRCm38	17	46,432,185 - 46,438,477 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	46,432,183 - 46,438,457 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	46,569,134 - 46,575,426 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	17	45,895,372 - 45,901,620 (-)	NCBI			mm8
Celera	17	49,867,036 - 49,874,196 (-)	NCBI		Celera
Cytogenetic Map	17	C	NCBI

Slc22a7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	9,204,322 - 9,210,086 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	9,204,414 - 9,210,350 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC22A7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	6	44,182,287 - 44,189,567 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	44,182,288 - 44,189,097 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	6	42,888,110 - 42,897,556 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

SLC22A7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	11,781,623 - 11,788,256 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Slc22a7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936476	16,675,377 - 16,680,209 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC22A7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	38,328,419 - 38,334,879 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	38,328,474 - 38,334,879 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	43,828,928 - 43,834,428 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC22A7
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	28,848,115 - 28,856,298 (-)	NCBI
ChlSab1.1 Ensembl	17	28,846,791 - 28,855,355 (-)	Ensembl

Slc22a7
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624754	16,275,689 - 16,282,141 (-)	NCBI

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70226	Eae4	Experimental allergic encephalomyelitis QTL 4			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	9	1	29467098	Rat
9589055	Scfw5	Subcutaneous fat weight QTL 5	5.55	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	9	1	40383872	Rat
9589158	Gluco65	Glucose level QTL 65	6.82	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	9	1	40383872	Rat
7411592	Foco8	Food consumption QTL 8	7.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	1	40383872	Rat
1300124	Cm4	Cardiac mass QTL 4	3.55		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	9	1	45029794	Rat
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1055222	93442944	Rat
1298088	Edpm11	Estrogen-dependent pituitary mass QTL 11	2.5		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	2355722	47355722	Rat
1641911	Alcrsp13	Alcohol response QTL 13			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	2355722	47355722	Rat
61425	Cia15	Collagen induced arthritis QTL 15	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	9	2880977	47375681	Rat
631211	Bw4	Body weight QTL4	5.31		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	9	2880977	47880977	Rat
1354650	Despr5	Despair related QTL 5	4.01	0.0017	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	9	4986095	49986095	Rat
2303559	Gluco54	Glucose level QTL 54	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	4986095	49986095	Rat
61450	Ciaa3	CIA Autoantibody QTL 3	6.5		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	9	5724254	25692342	Rat
11353947	Bp392	Blood pressure QTL 392			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	12216771	57216771	Rat
9589133	Insul26	Insulin level QTL 26	17.96	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	9	12425463	57425463	Rat
7411609	Foco16	Food consumption QTL 16	25.6	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	12425463	57425463	Rat
1600365	Mcs20	Mammary carcinoma susceptibility QTL 20	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	9	15554901	47249201	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	90
Count of miRNA genes:	75
Interacting mature miRNAs:	79
Transcripts:	ENSRNOT00000025094
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	23	23		23				7
Low	7	6		6			2	14	2
Below cutoff	16	10	7	10	2	2	61	2	11	10	2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053537	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AABR07066814	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01058292	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY816233	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L27651	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000025094 ⟹ ENSRNOP00000025094

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	9	16,924,520 - 16,931,766 (+)	Ensembl

RefSeq Acc Id:

NM_053537 ⟹ NP_445989

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	16,925,321 - 16,931,119 (+)	NCBI
Rnor_5.0	9	15,822,368 - 15,828,166 (+)	NCBI
RGSC_v3.4	9	9,934,309 - 9,940,107 (+)	RGD
Celera	9	12,295,095 - 12,300,893 (+)	RGD

Sequence:

show sequence

GTGGGTGGGTAGCATGGGCTTCGAAGACCTGCTGGACAAGGTGGGCGGCTTTGGGCCCTTCCAA
CTTCGGAATCTGGTTCTGATGGCCCTGCCCCGAATGCTGCTCCCCATGCACTTTCTCCTGCCCG
TCTTCATGGCCGCTGTGCCTGCCCACCATTGTGCCCTGCCCGGTGCCCCTGCCAACCTCAGTCA
CCAGGACTTATGGCTGGAAGCCCATCTACCCCGGGAGACTGACGGCAGCTTTAGCTCCTGCCTC
CGATTTGCCTATCCCCAGACTGTCCCCAATGTCACTTTGGGGACAGAGGTGTCCAACTCTGGGG
AGCCTGAGGGTGAGCCCCTCACGGTGCCCTGCTCTCAGGGCTGGGAGTACGACCGCTCAGAATT
CTCCTCCACCATTGCAACTGAGTGGGATCTTGTGTGTCAGCAGAGAGGACTGAACAAAATTACG
TCCACCTGCTTCTTCATTGGTGTGCTGGTGGGAGCCGTGGTGTATGGATACTTGTCTGACAGGT
TTGGCAGGCGCCGGCTTCTGCTGGTGGCCTACGTGAGCTCCCTGGTGCTGGGTCTGATGTCTGC
AGCCTCCATCAACTACATCATGTTCGTAGTCACCCGTACACTCACCGGCTCAGCCCTGGCTGGC
TTCACCATCATTGTGCTCCCACTGGAGTTGGAGTGGCTGGATGTGGAGCACCGCACTGTGGCCG
GGGTCATCAGCACCGTCTTCTGGTCGGGAGGCGTGCTGCTGCTGGCACTGGTGGGCTACCTGAT
CCGGAGCTGGCGCTGGCTTCTGCTGGCTGCCACCCTGCCGTGTGTCCCAGGCATCATCAGCATC
TGGTGGGTTCCTGAGTCTGCACGGTGGCTTCTAACCCAGGGTCGTGTGGAGGAGGCAAAAAAAT
ACTTGCTGAGCTGTGCCAAGCTCAATGGGCGGCCCGTGGGTGAGGGCAGCCTGAGCCAGGAGGC
CCTGAACAACGTGGTCACCATGGAAAGGGCGTTGCAAAGACCCTCATACTTAGACCTGTTCCGA
ACATCTCAGCTCCGACATATCTCACTGTGCTGCATGATGGTGTGGTTTGGAGTGAACTTTTCCT
ACTACGGCCTGACTCTGGACGTGTCTGGGCTGGGGCTGAACGTGTACCAGACACAGCTGCTGTT
TGGGGCTGTGGAGCTCCCCTCCAAAATTATGGTCTACTTCCTTGTGCGCCGTCTGGGACGCCGT
CTCACGGAGGCTGGGATGCTGCTGGGCGCTGCTCTGACCTTTGGCACCAGCCTGCTGGTATCCT
TGGAGACTAAGTCATGGATCACTGCTCTGGTGGTGGTGGGGAAAGCTTTTTCTGAAGCTGCTTT
TACTACGGCCTACCTGTTCACGTCCGAGTTGTACCCTACTGTGCTCAGACAGACAGGATTGGGA
CTTACTGCACTCATGGGCAGGCTAGGGGCCTCTCTGGCCCCACTGGCGGCCTTGCTGGATGGAG
TGTGGCTGTTGCTGCCCAAAGTTGCTTACGGGGGGATTGCCCTGGTGGCTGCCTGCACTGCACT
CCTGCTGCCTGAGACGAAGAAGGCACAGCTGCCAGAGACCATCCAGGATGTGGAGAGGAAGAGT
ACCCAGGAGGAAGATGTGTAGGTCCGGGACTGAGTT

hide sequence

Protein Sequences


Protein RefSeqs	NP_445989	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA57157	(Get FASTA)	NCBI Sequence Viewer
	AAV66454	(Get FASTA)	NCBI Sequence Viewer
	EDM18823	(Get FASTA)	NCBI Sequence Viewer
	Q5RLM2	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_445989 ⟸ NM_053537

- UniProtKB:

Q5RLM2 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MGFEDLLDKVGGFGPFQLRNLVLMALPRMLLPMHFLLPVFMAAVPAHHCALPGAPANLSHQDLW
LEAHLPRETDGSFSSCLRFAYPQTVPNVTLGTEVSNSGEPEGEPLTVPCSQGWEYDRSEFSSTI
ATEWDLVCQQRGLNKITSTCFFIGVLVGAVVYGYLSDRFGRRRLLLVAYVSSLVLGLMSAASIN
YIMFVVTRTLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTVFWSGGVLLLALVGYLIRSWR
WLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLLSCAKLNGRPVGEGSLSQEALNNV
VTMERALQRPSYLDLFRTSQLRHISLCCMMVWFGVNFSYYGLTLDVSGLGLNVYQTQLLFGAVE
LPSKIMVYFLVRRLGRRLTEAGMLLGAALTFGTSLLVSLETKSWITALVVVGKAFSEAAFTTAY
LFTSELYPTVLRQTGLGLTALMGRLGASLAPLAALLDGVWLLLPKVAYGGIALVAACTALLLPE
TKKAQLPETIQDVERKSTQEEDV

hide sequence

RefSeq Acc Id:

ENSRNOP00000025094 ⟸ ENSRNOT00000025094

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696520

Promoter ID:

EPDNEW_R7045

Type:

multiple initiation site

Name:

Slc22a7_2

Description:

solute carrier family 22 member 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R7046

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	16,924,502 - 16,924,562	EPDNEW

RGD ID:

13696521

Promoter ID:

EPDNEW_R7046

Type:

initiation region

Name:

Slc22a7_1

Description:

solute carrier family 22 member 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R7045

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	16,925,258 - 16,925,318	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Damaging Variants

Assembly: Rnor_5.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
9	15822653	15822654	T	A	snv	LEC/Tj (KyushuU)

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621699	AgrOrtholog
Ensembl Genes	ENSRNOG00000018420	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000025094	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000025094	ENTREZGENE, UniProtKB/Swiss-Prot
InterPro	MFS_dom	UniProtKB/Swiss-Prot
	MFS_sugar_transport-like	UniProtKB/Swiss-Prot
	MFS_trans_sf	UniProtKB/Swiss-Prot
	Orgcat_transp/SVOP	UniProtKB/Swiss-Prot
KEGG Report	rno:89776	UniProtKB/Swiss-Prot
NCBI Gene	89776	ENTREZGENE
Pfam	Sugar_tr	UniProtKB/Swiss-Prot
PharmGKB	SLC22A7	RGD
PhenoGen	Slc22a7	PhenoGen
PROSITE	MFS	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF103473	UniProtKB/Swiss-Prot
TIGRFAMs	2A0119	UniProtKB/Swiss-Prot
UniGene	Rn.10009	ENTREZGENE
UniProt	Q5RLM2	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q63314	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-24	Slc22a7	solute carrier family 22 member 7	Slc22a7	solute carrier family 22 (organic anion transporter), member 7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-02-26	Slc22a7	solute carrier family 22 (organic anion transporter), member 7			Symbol and Name status set to approved	625702	APPROVED
2002-08-07	Slc22a7	solute carrier family 22 (organic anion transporter), member 7			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	abundant in male liver compared to kidney; higher expression in female livers and kidneys	70250
gene_regulation	testosterone down regulates expression	70250

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

RGD Manual Annotations

Imported Annotations - KEGG (archival)