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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621699
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc22a7
Name: solute carrier family 22 member 7
Acc ID: CHEBI:16742
Term: orotic acid
Definition: A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Chemical ID: MESH:D009963
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases exportEXP 6480464CTDSLC22A7 protein results in increased export of Orotic Acid

PMID:22981274
multiple interactionsEXP 6480464CTD4-Aminobenzoic Acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid], [Orotic Acid co-treated with Benzoic Acid] promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid], Benzoic Acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid], cinnamic acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid], Niacin promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid], Orotic Acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid], phenylacetic acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid], Salicylic Acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid]

PMID:22981274
increases exportISORGD:7326866480464CTDSLC22A7 protein results in increased export of Orotic Acid

PMID:22981274
multiple interactionsISORGD:7326866480464CTD4-Aminobenzoic Acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid], [Orotic Acid co-treated with Benzoic Acid] promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid], Benzoic Acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid], cinnamic acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid], gamma-Aminobutyric Acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid], Niacin promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid], Orotic Acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid], phenylpyruvic acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid], Salicylic Acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid]

PMID:22981274
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.