Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Fam135a | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Fam135a (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of FAM135A mRNA | CTD | PMID:22206623 | Fam135a | Rat | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of FAM135A mRNA | CTD | PMID:32145629 | Fam135a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Fam135a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of FAM135A mRNA | CTD | PMID:24680724 | Fam135a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FAM135A mRNA | CTD | PMID:33387578 | Fam135a | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | FAM135A (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of FAM135A mRNA | CTD | PMID:30851411 | Fam135a | Rat | aflatoxin B1 | increases expression | ISO | Fam135a (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of FAM135A mRNA | CTD | PMID:19770486 | Fam135a | Rat | aflatoxin B1 | decreases methylation | ISO | FAM135A (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of FAM135A gene | CTD | PMID:27153756 | Fam135a | Rat | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of FAM135A mRNA | CTD | PMID:30779732 | Fam135a | Rat | aristolochic acid A | decreases expression | ISO | FAM135A (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of FAM135A mRNA | CTD | PMID:33212167 | Fam135a | Rat | atrazine | decreases expression | ISO | FAM135A (Homo sapiens) | 6480464 | Atrazine results in decreased expression of FAM135A mRNA | CTD | PMID:22378314 | Fam135a | Rat | azoxystrobin | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FAM135A mRNA | CTD | PMID:33854195 | Fam135a | Rat | benzo[a]pyrene | increases expression | ISO | Fam135a (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of FAM135A mRNA | CTD | PMID:20127859 | Fam135a | Rat | benzo[a]pyrene | affects methylation | ISO | FAM135A (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of FAM135A 5' UTR | CTD | PMID:27901495 | Fam135a | Rat | benzo[a]pyrene | increases expression | ISO | FAM135A (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of FAM135A mRNA | CTD | PMID:26238291 | Fam135a | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FAM135A mRNA | CTD | PMID:25181051 | Fam135a | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of FAM135A mRNA | CTD | PMID:32145629 | Fam135a | Rat | bisphenol A | increases expression | ISO | FAM135A (Homo sapiens) | 6480464 | bisphenol A results in increased expression of FAM135A mRNA | CTD | PMID:29275510 | Fam135a | Rat | cadmium dichloride | decreases expression | ISO | Fam135a (Mus musculus) | 6480464 | Cadmium Chloride results in decreased expression of FAM135A mRNA | CTD | PMID:24982889 | Fam135a | Rat | caffeine | affects phosphorylation | ISO | FAM135A (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of FAM135A protein | CTD | PMID:35688186 | Fam135a | Rat | chlorpyrifos | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FAM135A mRNA | CTD | PMID:33854195 | Fam135a | Rat | cisplatin | increases expression | ISO | FAM135A (Homo sapiens) | 6480464 | Cisplatin results in increased expression of FAM135A mRNA | CTD | PMID:27594783 | Fam135a | Rat | cisplatin | decreases expression | ISO | FAM135A (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of FAM135A mRNA | CTD | PMID:27392435 | Fam135a | Rat | cisplatin | multiple interactions | ISO | FAM135A (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of FAM135A mRNA | CTD | PMID:27392435 | Fam135a | Rat | copper(II) sulfate | increases expression | ISO | FAM135A (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of FAM135A mRNA | CTD | PMID:19549813 | Fam135a | Rat | cyclosporin A | increases expression | ISO | FAM135A (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of FAM135A mRNA | CTD | PMID:25562108 | Fam135a | Rat | cyclosporin A | increases methylation | ISO | FAM135A (Homo sapiens) | 6480464 | Cyclosporine results in increased methylation of FAM135A promoter | CTD | PMID:27989131 | Fam135a | Rat | Dibutyl phosphate | affects expression | ISO | FAM135A (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of FAM135A mRNA | CTD | PMID:37042841 | Fam135a | Rat | dorsomorphin | multiple interactions | ISO | FAM135A (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FAM135A mRNA | CTD | PMID:27188386 | Fam135a | Rat | epoxiconazole | increases expression | ISO | Fam135a (Mus musculus) | 6480464 | epoxiconazole results in increased expression of FAM135A mRNA | CTD | PMID:35436446 | Fam135a | Rat | ethanol | decreases expression | ISO | Fam135a (Mus musculus) | 6480464 | Ethanol results in decreased expression of FAM135A mRNA | CTD | PMID:29018328 | Fam135a | Rat | ethanol | affects expression | ISO | Fam135a (Mus musculus) | 6480464 | Ethanol affects the expression of FAM135A mRNA | CTD | PMID:30319688 | Fam135a | Rat | folic acid | decreases expression | ISO | Fam135a (Mus musculus) | 6480464 | Folic Acid results in decreased expression of FAM135A mRNA | CTD | PMID:25629700 | Fam135a | Rat | FR900359 | decreases phosphorylation | ISO | FAM135A (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of FAM135A protein | CTD | PMID:37730182 | Fam135a | Rat | glyphosate | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FAM135A mRNA | CTD | PMID:33854195 | Fam135a | Rat | imidacloprid | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FAM135A mRNA | CTD | PMID:33854195 | Fam135a | Rat | lipopolysaccharide | multiple interactions | ISO | FAM135A (Homo sapiens) | 6480464 | [Lipopolysaccharides co-treated with resveratrol] results in decreased expression of FAM135A mRNA | CTD | PMID:26667767 | Fam135a | Rat | mercury dichloride | decreases expression | ISO | FAM135A (Homo sapiens) | 6480464 | Mercuric Chloride results in decreased expression of FAM135A mRNA | CTD | PMID:27188386 | Fam135a | Rat | methyl methanesulfonate | decreases expression | ISO | FAM135A (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of FAM135A mRNA | CTD | PMID:23649840 | Fam135a | Rat | nitrofen | decreases expression | EXP | | 6480464 | nitrofen results in decreased expression of FAM135A mRNA | CTD | PMID:33484710 | Fam135a | Rat | paracetamol | decreases expression | ISO | FAM135A (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of FAM135A mRNA | CTD | PMID:21420995 | Fam135a | Rat | potassium dichromate | decreases expression | ISO | Fam135a (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of FAM135A mRNA | CTD | PMID:23608068 | Fam135a | Rat | quercetin | increases expression | ISO | FAM135A (Homo sapiens) | 6480464 | Quercetin results in increased expression of FAM135A mRNA | CTD | PMID:21632981 | Fam135a | Rat | rac-lactic acid | decreases expression | ISO | FAM135A (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of FAM135A mRNA | CTD | PMID:30851411 | Fam135a | Rat | resveratrol | multiple interactions | ISO | FAM135A (Homo sapiens) | 6480464 | [Lipopolysaccharides co-treated with resveratrol] results in decreased expression of FAM135A mRNA | CTD | PMID:26667767 | Fam135a | Rat | SB 431542 | multiple interactions | ISO | FAM135A (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FAM135A mRNA | CTD | PMID:27188386 | Fam135a | Rat | sodium arsenite | decreases expression | ISO | FAM135A (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of FAM135A mRNA | CTD | PMID:29301061 | Fam135a | Rat | sodium arsenite | increases expression | ISO | FAM135A (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of FAM135A mRNA | CTD | PMID:38568856 | Fam135a | Rat | sunitinib | increases expression | ISO | FAM135A (Homo sapiens) | 6480464 | Sunitinib results in increased expression of FAM135A mRNA | CTD | PMID:31533062 | Fam135a | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of FAM135A mRNA | CTD | PMID:31150632 | Fam135a | Rat | tetrachloromethane | increases expression | ISO | Fam135a (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of FAM135A mRNA | CTD | PMID:31919559 | Fam135a | Rat | tetraphene | increases expression | ISO | Fam135a (Mus musculus) | 6480464 | benz(a)anthracene results in increased expression of FAM135A mRNA | CTD | PMID:26377693 | Fam135a | Rat | thiabendazole | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FAM135A mRNA | CTD | PMID:33854195 | Fam135a | Rat | thimerosal | affects expression | ISO | FAM135A (Homo sapiens) | 6480464 | Thimerosal affects the expression of FAM135A mRNA | CTD | PMID:27188386 | Fam135a | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of FAM135A mRNA | CTD | PMID:34492290 | Fam135a | Rat | titanium dioxide | decreases methylation | ISO | Fam135a (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of FAM135A gene | CTD | PMID:35295148 | Fam135a | Rat | trichostatin A | increases expression | ISO | FAM135A (Homo sapiens) | 6480464 | trichostatin A results in increased expression of FAM135A mRNA | CTD | PMID:24935251 | Fam135a | Rat | trimellitic anhydride | decreases expression | ISO | Fam135a (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of FAM135A mRNA | CTD | PMID:19042947 | Fam135a | Rat | triphenyl phosphate | affects expression | ISO | FAM135A (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of FAM135A mRNA | CTD | PMID:37042841 | Fam135a | Rat | valproic acid | increases expression | ISO | FAM135A (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of FAM135A mRNA | CTD | PMID:24935251 and PMID:29154799 | Fam135a | Rat | valproic acid | multiple interactions | ISO | FAM135A (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FAM135A mRNA | CTD | PMID:27188386 | Fam135a | Rat | valproic acid | decreases expression | ISO | FAM135A (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of FAM135A mRNA | CTD | PMID:24383497 and PMID:26272509 | Fam135a | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of FAM135A mRNA | CTD | PMID:23034163 | Fam135a | Rat | vorinostat | affects expression | ISO | FAM135A (Homo sapiens) | 6480464 | vorinostat affects the expression of FAM135A mRNA | CTD | PMID:27188386 | |