Kif6 (kinesin family member 6) - Rat Genome Database

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Gene: Kif6 (kinesin family member 6) Rattus norvegicus
Analyze
Symbol: Kif6
Name: kinesin family member 6
RGD ID: 621070
Description: Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in spermatogenesis. Located in male germ cell nucleus. Human ortholog(s) of this gene implicated in artery disease (multiple) and type 2 diabetes mellitus. Orthologous to human KIF6 (kinesin family member 6); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: kinesin-like protein KIF6; kinesin-related protein 3; Krp3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8918,573,925 - 18,870,789 (-)NCBIGRCr8
mRatBN7.2911,076,203 - 11,373,205 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl911,072,824 - 11,373,006 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0913,016,973 - 13,311,971 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl913,030,673 - 13,311,924 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0911,952,731 - 12,245,956 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.496,298,833 - 6,589,880 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.196,436,830 - 6,589,825 (-)NCBI
Celera98,852,140 - 9,147,543 (-)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Investigation of KIF6 Trp719Arg in a case-control study of myocardial infarction: a Costa Rican population. Bare LA, etal., PLoS One. 2010 Sep 29;5(9):e13081. doi: 10.1371/journal.pone.0013081.
2. Association between rs20456 and rs6930913 of Kinesin-Like Family 6 and Hypertension in a Chinese Cohort. Chen YL, etal., Int J Hypertens. 2021 Dec 18;2021:1061800. doi: 10.1155/2021/1061800. eCollection 2021.
3. The polymorphism Trp719Arg in the kinesin-like protein 6 is associated with the presence of late outgrowth endothelial progenitor cells in acute myocardial infarction. Davani S, etal., Atherosclerosis. 2010 May;210(1):48-50. doi: 10.1016/j.atherosclerosis.2009.11.041. Epub 2009 Nov 29.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Impact of KIF6 Polymorphism rs20455 on Coronary Heart Disease Risk and Effectiveness of Statin Therapy in 100 Patients from Southern Iran. Hamidizadeh L, etal., Arch Iran Med. 2015 Oct;18(10):683-7. doi: 0151810/AIM.008.
6. Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and cardiovascular risk and efficacy of atorvastatin among subjects with diabetes on dialysis: the 4D study. Hoffmann MM, etal., Atherosclerosis. 2011 Dec;219(2):659-62. doi: 10.1016/j.atherosclerosis.2011.07.126. Epub 2011 Aug 5.
7. No impact of KIF6 genotype on vascular risk and statin response among 18,348 randomized patients in the heart protection study. Hopewell JC, etal., J Am Coll Cardiol. 2011 May 17;57(20):2000-7. doi: 10.1016/j.jacc.2011.02.015. Epub 2011 Mar 31.
8. KIF6 719Arg Genetic Variant and Risk for Thoracic Aortic Dissection. Iakoubova OA, etal., Aorta (Stamford). 2016 Jun 1;4(3):83-90. doi: 10.12945/j.aorta.2016.16.003. eCollection 2016 Jun.
9. Polymorphisms associated with both noncardioembolic stroke and coronary heart disease: vienna stroke registry. Luke MM, etal., Cerebrovasc Dis. 2009;28(5):499-504. Epub 2009 Sep 12.
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Effect of pravastatin therapy on coronary events in carriers of the KIF6 719Arg allele from the cholesterol and recurrent events trial. Shiffman D, etal., Am J Cardiol. 2010 May 1;105(9):1300-5. doi: 10.1016/j.amjcard.2009.12.049. Epub 2010 Mar 20.
15. A kinesin family member 6 variant is associated with coronary heart disease in the Women's Health Study. Shiffman D, etal., J Am Coll Cardiol. 2008 Jan 29;51(4):444-8. doi: 10.1016/j.jacc.2007.09.044.
16. Kinesin-related proteins in the mammalian testes: candidate motors for meiosis and morphogenesis. Sperry AO and Zhao LP, Mol Biol Cell 1996 Feb;7(2):289-305.
17. Kinesin family member 6 variant Trp719Arg does not associate with angiographically defined coronary artery disease in the Ottawa Heart Genomics Study. Stewart AF, etal., J Am Coll Cardiol. 2009 Apr 21;53(16):1471-2. doi: 10.1016/j.jacc.2008.12.051.
18. Investigation of KIF6 Trp719Arg gene polymorphism in a case-control study of coronary artery disease and non-fatal myocardial infarction in the Eastern Province of Saudi Arabia. Vatte C, etal., Ann Saudi Med. 2016 Mar-Apr;36(2):105-11. doi: 10.5144/0256-4947.2016.21.3.1140. Epub 2016 Mar 21.
19. Novel KIF6 polymorphism increases susceptibility to type 2 diabetes mellitus and coronary heart disease in Han Chinese men. Wu G, etal., J Diabetes Res. 2014;2014:871439. doi: 10.1155/2014/871439. Epub 2014 Dec 31.
20. KRP3A and KRP3B: candidate motors in spermatid maturation in the seminiferous epithelium. Zou Y, etal., Biol Reprod 2002 Mar;66(3):843-55.

Genomics

Comparative Map Data
Kif6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8918,573,925 - 18,870,789 (-)NCBIGRCr8
mRatBN7.2911,076,203 - 11,373,205 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl911,072,824 - 11,373,006 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0913,016,973 - 13,311,971 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl913,030,673 - 13,311,924 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0911,952,731 - 12,245,956 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.496,298,833 - 6,589,880 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.196,436,830 - 6,589,825 (-)NCBI
Celera98,852,140 - 9,147,543 (-)NCBICelera
Cytogenetic Map9q12NCBI
KIF6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38639,329,990 - 39,725,408 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl639,329,990 - 39,725,408 (-)EnsemblGRCh38hg38GRCh38
GRCh37639,297,766 - 39,693,184 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36639,410,854 - 39,801,159 (-)NCBINCBI36Build 36hg18NCBI36
Celera640,856,140 - 41,246,459 (-)NCBICelera
Cytogenetic Map6p21.2NCBI
HuRef639,021,337 - 39,411,588 (-)NCBIHuRef
CHM1_1639,305,522 - 39,695,792 (-)NCBICHM1_1
T2T-CHM13v2.0639,154,539 - 39,549,934 (-)NCBIT2T-CHM13v2.0
Kif6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391749,922,121 - 50,216,875 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1749,922,164 - 50,216,875 (+)EnsemblGRCm39 Ensembl
GRCm381749,615,098 - 49,909,847 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1749,615,136 - 49,909,847 (+)EnsemblGRCm38mm10GRCm38
MGSCv371749,754,497 - 50,049,172 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361749,080,745 - 49,381,758 (+)NCBIMGSCv36mm8
Celera1753,043,362 - 53,345,234 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1725.78NCBI
Kif6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554376,352,316 - 6,671,934 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554376,353,318 - 6,597,196 (-)NCBIChiLan1.0ChiLan1.0
KIF6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2553,824,728 - 54,214,664 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1649,694,312 - 50,084,294 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0638,917,083 - 39,306,190 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1640,234,045 - 40,616,522 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl640,234,426 - 40,616,738 (-)Ensemblpanpan1.1panPan2
KIF6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1128,251,747 - 8,613,297 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl128,242,582 - 8,613,580 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha128,258,382 - 8,645,157 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0128,712,641 - 9,092,058 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl128,718,848 - 9,092,579 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1128,239,760 - 8,626,748 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0128,317,282 - 8,697,965 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0128,422,813 - 8,803,435 (-)NCBIUU_Cfam_GSD_1.0
Kif6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494643,646,295 - 44,023,082 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647619,937,219 - 20,311,249 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647619,937,141 - 20,311,988 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIF6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl734,918,893 - 35,096,036 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1734,740,336 - 35,096,044 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2739,896,558 - 40,225,332 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KIF6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11732,425,890 - 32,804,069 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1732,510,781 - 32,804,554 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604439,338,019 - 39,723,552 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kif6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475418,693,529 - 19,010,522 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475418,693,415 - 19,011,538 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:46
Count of miRNA genes:45
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000015584
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9534647950346479Rat
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9121707400Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9875049253750492Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)9131250552Rat
1578675Bss17Bone structure and strength QTL 173.8femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)9360535521031556Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)949664545496645Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9621499551214995Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9875049253750492Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9141763315Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9534647950416711Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9671488829567695Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)949664545496645Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)949664545496645Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9621499551214995Rat

Markers in Region
D9Rat82  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8918,809,464 - 18,809,684 (+)Marker Load Pipeline
mRatBN7.2911,311,738 - 11,311,958 (+)MAPPERmRatBN7.2
Rnor_6.0913,250,478 - 13,250,697NCBIRnor6.0
Rnor_5.0912,185,679 - 12,185,898UniSTSRnor5.0
RGSC_v3.496,521,013 - 6,521,233RGDRGSC3.4
RGSC_v3.496,521,014 - 6,521,233UniSTSRGSC3.4
RGSC_v3.196,521,014 - 6,521,233RGD
Celera99,086,396 - 9,086,615UniSTS
RH 3.4 Map96.3UniSTS
RH 3.4 Map96.3RGD
RH 2.0 Map912.3RGD
SHRSP x BN Map95.8599RGD
Cytogenetic Map9q11UniSTS
D9Rat88  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8918,621,425 - 18,621,623 (+)Marker Load Pipeline
mRatBN7.2911,123,702 - 11,123,900 (+)MAPPERmRatBN7.2
Rnor_6.0913,064,479 - 13,064,676NCBIRnor6.0
Rnor_5.0911,999,651 - 11,999,848UniSTSRnor5.0
RGSC_v3.496,330,235 - 6,330,432UniSTSRGSC3.4
RGSC_v3.496,330,234 - 6,330,432RGDRGSC3.4
RGSC_v3.196,330,235 - 6,330,432RGD
Celera98,897,647 - 8,897,854UniSTS
RH 3.4 Map98.8RGD
RH 3.4 Map98.8UniSTS
RH 2.0 Map914.4RGD
SHRSP x BN Map95.8999RGD
FHH x ACI Map91.12RGD
Cytogenetic Map9q11UniSTS
D9Got13  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2911,248,805 - 11,248,969 (+)MAPPERmRatBN7.2
Rnor_6.0913,188,487 - 13,188,650NCBIRnor6.0
Rnor_5.0912,123,793 - 12,123,956UniSTSRnor5.0
RGSC_v3.496,457,574 - 6,457,738RGDRGSC3.4
RGSC_v3.496,457,575 - 6,457,738UniSTSRGSC3.4
RGSC_v3.196,457,575 - 6,457,738RGD
Celera99,021,923 - 9,022,086UniSTS
RH 3.4 Map94.5UniSTS
RH 3.4 Map94.5RGD
Cytogenetic Map9q11UniSTS
RH130619  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2911,089,123 - 11,089,303 (+)MAPPERmRatBN7.2
Rnor_6.0913,029,895 - 13,030,074NCBIRnor6.0
Rnor_5.0911,965,653 - 11,965,832UniSTSRnor5.0
Celera98,865,063 - 8,865,242UniSTS
RH 3.4 Map913.9UniSTS
Cytogenetic Map9q11UniSTS
AU046623  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2911,227,066 - 11,227,350 (+)MAPPERmRatBN7.2
Rnor_6.0913,166,750 - 13,167,033NCBIRnor6.0
Rnor_5.0912,102,056 - 12,102,339UniSTSRnor5.0
RGSC_v3.496,435,838 - 6,436,121UniSTSRGSC3.4
Celera99,000,306 - 9,000,544UniSTS
Cytogenetic Map9q11UniSTS
AU049286  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2911,311,738 - 11,311,993 (+)MAPPERmRatBN7.2
Rnor_6.0913,250,478 - 13,250,732NCBIRnor6.0
Rnor_5.0912,185,679 - 12,185,933UniSTSRnor5.0
RGSC_v3.496,521,014 - 6,521,268UniSTSRGSC3.4
Celera99,086,396 - 9,086,650UniSTS
Cytogenetic Map9q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 3 30 108 78 81 58 14 58 5 170 55 93 45 60 23

Sequence


Ensembl Acc Id: ENSRNOT00000015584   ⟹   ENSRNOP00000015584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl911,072,824 - 11,373,006 (-)Ensembl
Rnor_6.0 Ensembl913,030,673 - 13,311,924 (-)Ensembl
RefSeq Acc Id: XM_006244480   ⟹   XP_006244542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8918,573,925 - 18,870,789 (-)NCBI
mRatBN7.2911,076,203 - 11,373,205 (-)NCBI
Rnor_6.0913,016,973 - 13,311,971 (-)NCBI
Rnor_5.0911,952,731 - 12,245,956 (-)NCBI
Sequence:
RefSeq Acc Id: XP_006244542   ⟸   XM_006244480
- Sequence:
Ensembl Acc Id: ENSRNOP00000015584   ⟸   ENSRNOT00000015584
Protein Domains
Kinesin motor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PSL8-F1-model_v2 AlphaFold E9PSL8 1-746 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696489
Promoter ID:EPDNEW_R7007
Type:single initiation site
Name:Kif6_1
Description:kinesin family member 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0913,311,926 - 13,311,986EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621070 AgrOrtholog
BioCyc Gene G2FUF-28343 BioCyc
Ensembl Genes ENSRNOG00000011453 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015584.8 UniProtKB/TrEMBL
Gene3D-CATH 3.40.850.10 UniProtKB/TrEMBL
InterPro Kinesin-like_fam UniProtKB/TrEMBL
  Kinesin_motor_CS UniProtKB/TrEMBL
  Kinesin_motor_dom UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report rno:171291 UniProtKB/TrEMBL
NCBI Gene 171291 ENTREZGENE
PANTHER KINESIN-LIKE PROTEIN KIF6 UniProtKB/TrEMBL
  KINESIN-RELATED UniProtKB/TrEMBL
Pfam Kinesin UniProtKB/TrEMBL
PhenoGen Kif6 PhenoGen
PRINTS KINESINHEAVY UniProtKB/TrEMBL
PROSITE KINESIN_MOTOR_DOMAIN1 UniProtKB/TrEMBL
  KINESIN_MOTOR_DOMAIN2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011453 RatGTEx
SMART KISc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A6JIC2_RAT UniProtKB/TrEMBL
  A6JIC3_RAT UniProtKB/TrEMBL
  A6JIC4_RAT UniProtKB/TrEMBL
  E9PSL8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Kif6  kinesin family member 6  Krp3  kinesin-related protein 3  Symbol and Name updated 1299863 APPROVED
2002-08-07 Krp3  kinesin-related protein 3      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains has a conserved motor domain that can form a limited coiled-coil secondary structure, and a globular tail domain 633049
gene_expression cDNA isolated from the rat testis 633049
gene_product member of the kinesin superfamily 633049
gene_transcript present in two isoforms 633049