Bp332 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp332 (Blood pressure QTL 332) Rattus norvegicus

Symbol: Bp332
Name: Blood pressure QTL 332
RGD ID: 2303170
Previously known as: CRYG locus
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: mean arterial blood pressure   (CMO:0000009)    
LOD Score: 3.73
P Value: 0.027
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr896,714,888 - 84,474,983RGD_MAPPER_PIPELINE
mRatBN7.2955,847,841 - 77,026,453RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0960,810,298 - 82,732,466RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0959,092,893 - 82,501,727RGDRnor5.0
RGSC_v3.491,526,958 - 74,813,097RGDRGSC3.4
Cross Type: intercross
Strains Crossed: WKY/NCrlCrlj SHR/Kyo 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Crygc is a candidate Gene for Bp332


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp332Rathypertension  IAGP 2303163 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp332Ratincreased systemic arterial systolic blood pressure  IDA 2303163 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp332Ratmean arterial blood pressure  IDA 2303163 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp332Ratcontrolled sodium content diet  IDA 2303163 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp332Ratvascular transducer tipped catheter  IDA 2303163 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp332RatSHR/Kyo  IEA 2303163 RGD 
Bp332RatWKY/NCrlCrlj  IEA 2303163 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp332Ratarterial blood pressure trait  IDA 2303163 RGD 


#
Reference Title
Reference Citation
1. Analysis and comparison of new candidate loci for hypertension between genetic hypertensive rat strains. Takami S, etal., Hypertens Res. 1996 Mar;19(1):51-6.
2. Blood pressure and proteinuria effects of multiple quantitative trait loci on rat chromosome 9 that differentiate the spontaneously hypertensive rat from the Dahl salt-sensitive rat. Toland EJ, etal., J Hypertens. 2008 Nov;26(11):2134-41.

Related QTL Description Reference
Bp333 maps to same region RGD:2302803



1 to 20 of 298 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1304775Ccdc150coiled-coil domain containing 15095579354455897341Rat
1309185Gtf3c3general transcription factor IIIC subunit 395588225255943037Rat
1586666C9h2orf66similar to human chromosome 2 open reading frame 6695594580655949855Rat
1303213Pgap1post-GPI attachment to proteins inositol deacylase 195597557456044325Rat
1561893Ankrd44ankyrin repeat domain 4495612674656427661Rat
11391487LOC108351932uncharacterized LOC10835193295632554556333506Rat
1586604Tmem258btransmembrane protein 258 B95645037356450755Rat
1590803Rpl11-ps6ribosomal protein L11, pseudogene 695646902356469614Rat
620148Sf3b1splicing factor 3b, subunit 195649240356532300Rat
1359509Coq10bcoenzyme Q10B95655375156573671Rat
621314Hspd1heat shock protein family D (Hsp60) member 195657919556590011Rat
2844Hspe1heat shock protein family E (Hsp10) member 195658991256593000Rat
620183Mob4MOB family member 4, phocein95661737456641336Rat
9179481LOC103690547glycine cleavage system H protein, mitochondrial pseudogene95663505656636545Rat
1307304Rftn2raftlin family member 295665161756707830Rat
1311527Mars2methionyl-tRNA synthetase 2, mitochondrial95672040856729991Rat
1559527Bollboule homolog, RNA binding protein95673489056859917Rat
708420Plcl1phospholipase C-like 195690157357238782Rat
41125672LOC120094794uncharacterized LOC12009479495690850256915395Rat
11390134LOC108351933uncharacterized LOC10835193395707161657113442Rat

1 to 20 of 298 rows
1 to 20 of 487 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
5065856AA99718618695590902155909207Ratregion
5060440BE11007517595590918155909356Ratregion
5030029BF4009099095594644755946537Ratregion
5056217RH14425123695597107355971309Ratregion
5053661RH14277814395597506655975209Ratregion
5044230RH13048421195612688456127095Ratregion
34862D9Rat2313495641096256411096Ratregion
66421D9Mco217895644711656447294Ratregion
66550D9Uia824795648057156480818Ratregion
5044256RH13049918695649120956491395Ratregion
5090419AU04973918495649343656493620Ratregion
5503148SF3B1-169195650592456506615Ratregion
2302967D9Mco7521495652412256524338Ratregion
44605D9Got5922395654765856547881Ratregion
5086396BQ20487715795657372856573885Ratregion
5049964RH13378321595657548456575699Ratregion
44604D9Got6021295660337256603584Ratregion
5055379RH14376715795661787556618032Ratregion
2302913D9Mco7621695662771356627933Ratregion
5083353AA81841911895663941356639531Ratregion
1 to 20 of 487 rows

Flank 1: (D9Bro1)
Rat AssemblyChrPosition (strand)Source
GRCr8984,474,983 - 84,475,093 (+)Marker Load Pipeline
mRatBN7.2977,026,343 - 77,026,453 (+)MAPPER
Rnor_6.0982,732,357 - 82,732,466NCBI
Rnor_5.0982,501,618 - 82,501,727UniSTS
RGSC_v3.4974,813,097 - 74,813,207RGD
RGSC_v3.4974,813,098 - 74,813,207UniSTS
RGSC_v3.1974,973,168 - 74,973,277RGD
RH 3.4 Map9757.3UniSTS
RH 3.4 Map9757.3RGD
Cytogenetic Map9q34UniSTS
Cytogenetic Map9q33UniSTS
Peak: (D9Mit2)
Rat AssemblyChrPosition (strand)Source
GRCr8973,930,789 - 73,930,979 (+)Marker Load Pipeline
mRatBN7.2966,437,052 - 66,437,242 (+)MAPPER
Rnor_6.0971,771,288 - 71,771,476NCBI
Rnor_5.0970,797,216 - 70,797,404UniSTS
RGSC_v3.4963,705,761 - 63,705,951RGD
RGSC_v3.4963,705,762 - 63,705,951UniSTS
RGSC_v3.1963,852,743 - 63,852,933RGD
Celera963,832,694 - 63,832,883UniSTS
RH 3.4 Map9588.2UniSTS
RH 3.4 Map9588.2RGD
RH 2.0 Map9632.5RGD
SHRSP x BN Map945.5498RGD
FHH x ACI Map942.29RGD
Cytogenetic Map9 RGD
Flank 2: (D9Mit6)
Rat AssemblyChrPosition (strand)Source
GRCr896,714,692 - 6,714,888 (+)Marker Load Pipeline
RGSC_v3.491,526,763 - 1,526,958UniSTS
RGSC_v3.191,526,762 - 1,526,958RGD


1 to 10 of 38 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)92375402458157242Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat

1 to 10 of 38 rows


Note Type Note Reference
qtl_cross_type intercross  
qtl_general measurement method: at 15 weeks of age weight of the animal was taken and a catheter implanted in the abdominal aorta via femoral artery; systolic and diastolic blood pressure and heart rate taken 3 times a day 2303163
qtl_general this locus cosegregates with diastolic and mean blood pressure 2303163