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Gene: Ndufs1 (NADH:ubiquinone oxidoreductase core subunit S1) Rattus norvegicus
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Symbol: Ndufs1
Name: NADH:ubiquinone oxidoreductase core subunit S1
Description: Predicted to contribute to NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in several processes, including apoptotic mitochondrial changes; reactive oxygen species metabolic process; and regulation of mitochondrial membrane potential. Predicted to localize to the mitochondrial intermembrane space and mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in inherited metabolic disorder and mitochondrial complex I deficiency. Orthologous to human NDUFS1 (NADH:ubiquinone oxidoreductase core subunit S1); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC93795; NADH dehydrogenase (ubiquinone) Fe-S protein 1; NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0969,919,863 - 69,953,182 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl969,919,867 - 69,953,182 (-)Ensembl
Rnor_5.0969,728,932 - 69,762,079 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4961,798,141 - 61,831,964 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1961,945,124 - 61,978,946 (-)NCBI
Celera961,964,379 - 61,997,783 (-)NCBICelera
Cytogenetic Map9q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ndufs1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1359670
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.