Tns1 (tensin 1) - Rat Genome Database

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Gene: Tns1 (tensin 1) Rattus norvegicus
Analyze
Symbol: Tns1
Name: tensin 1
RGD ID: 68427
Description: Predicted to enable metal ion binding activity and phosphoprotein phosphatase activity. Predicted to be involved in fibroblast migration. Predicted to act upstream of or within cell-substrate junction assembly. Predicted to be located in cell-substrate junction. Predicted to be active in focal adhesion. Orthologous to human TNS1 (tensin 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC301509; similar to tensin; tensin; tensin-1; Tns
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2975,491,886 - 75,702,853 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl975,495,814 - 75,703,225 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx983,949,371 - 84,156,277 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0989,078,281 - 89,285,195 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0987,464,486 - 87,671,405 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0981,190,192 - 81,401,020 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl981,194,119 - 81,400,987 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0980,960,130 - 81,166,699 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,235,556 - 73,444,200 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1973,382,620 - 73,386,133 (-)NCBI
Celera973,072,641 - 73,280,128 (-)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-Nitrobenzanthrone  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP,ISO)
Benoxacor  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
beta-hexachlorocyclohexane  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
C60 fullerene  (EXP)
caffeine  (ISO)
calyculin a  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
CGP 52608  (ISO)
chlordecone  (ISO)
ciglitazone  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP,ISO)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
fenamidone  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
glyphosate  (EXP,ISO)
Heptachlor epoxide  (ISO)
hexadecanoic acid  (ISO)
inulin  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
O-methyleugenol  (ISO)
orphenadrine  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenobarbital  (EXP,ISO)
potassium bromate  (ISO)
potassium chromate  (ISO)
progesterone  (EXP)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium dichromate  (ISO)
sunitinib  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genes for tensin, villin and desmin are linked on mouse chromosome 1. Jankowski SA and Gumucio DL, Mamm Genome 1995 Oct;6(10):744-5.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9087448   PMID:11023826   PMID:11792844   PMID:21423176   PMID:22658674  


Genomics

Comparative Map Data
Tns1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2975,491,886 - 75,702,853 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl975,495,814 - 75,703,225 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx983,949,371 - 84,156,277 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0989,078,281 - 89,285,195 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0987,464,486 - 87,671,405 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0981,190,192 - 81,401,020 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl981,194,119 - 81,400,987 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0980,960,130 - 81,166,699 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,235,556 - 73,444,200 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1973,382,620 - 73,386,133 (-)NCBI
Celera973,072,641 - 73,280,128 (-)NCBICelera
Cytogenetic Map9q33NCBI
TNS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382217,799,791 - 218,033,982 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2217,799,588 - 218,033,982 (-)EnsemblGRCh38hg38GRCh38
GRCh372218,664,514 - 218,867,718 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,372,757 - 218,517,041 (-)NCBINCBI36Build 36hg18NCBI36
Build 342218,493,009 - 218,634,267NCBI
Celera2212,432,401 - 212,576,690 (-)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2210,519,516 - 210,524,347 (-)NCBIHuRef
HuRef2210,526,374 - 210,662,745 (-)NCBIHuRef
CHM1_12218,670,911 - 218,815,174 (-)NCBICHM1_1
T2T-CHM13v2.02218,283,109 - 218,495,456 (-)NCBIT2T-CHM13v2.0
Tns1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39173,949,391 - 74,163,707 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl173,949,390 - 74,163,608 (-)EnsemblGRCm39 Ensembl
GRCm38173,910,232 - 74,124,548 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl173,910,231 - 74,124,449 (-)EnsemblGRCm38mm10GRCm38
MGSCv37173,956,805 - 74,171,021 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36173,843,438 - 74,057,654 (-)NCBIMGSCv36mm8
Celera174,471,979 - 74,685,728 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map138.17NCBI
Tns1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545315,260,286 - 15,479,519 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545315,289,722 - 15,483,970 (+)NCBIChiLan1.0ChiLan1.0
TNS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan12B120,448,853 - 120,661,063 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B105,061,135 - 105,273,098 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B223,666,272 - 223,852,483 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B223,666,273 - 223,805,653 (-)Ensemblpanpan1.1panPan2
TNS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13724,578,855 - 24,776,153 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3724,581,806 - 24,808,049 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3725,399,889 - 25,596,598 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03724,594,870 - 24,792,203 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3724,597,850 - 24,806,453 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13724,501,077 - 24,698,131 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03724,435,719 - 24,632,442 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03724,454,878 - 24,651,749 (-)NCBIUU_Cfam_GSD_1.0
Tns1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303174,102,338 - 174,311,852 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936569445,110 - 654,664 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936569447,730 - 654,662 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15119,951,091 - 120,164,713 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115119,948,133 - 120,143,797 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215133,071,108 - 133,110,920 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TNS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110103,665,575 - 103,886,824 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10103,669,412 - 103,879,641 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604095,520,792 - 95,727,467 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tns1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248236,956,918 - 7,150,058 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248236,956,913 - 7,149,854 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tns1
534 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:119
Count of miRNA genes:81
Interacting mature miRNAs:94
Transcripts:ENSRNOT00000035277
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95584784177026453Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95662771378595166Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)95662771378595166Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)95662771378595166Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat

Markers in Region
D9Got86  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2975,635,142 - 75,635,371 (+)MAPPERmRatBN7.2
Rnor_6.0981,333,033 - 81,333,268NCBIRnor6.0
Rnor_5.0981,098,731 - 81,098,966UniSTSRnor5.0
RGSC_v3.4973,376,109 - 73,376,338RGDRGSC3.4
RGSC_v3.4973,376,110 - 73,376,338UniSTSRGSC3.4
RGSC_v3.1973,523,092 - 73,523,320RGD
Celera973,212,433 - 73,212,661UniSTS
RH 3.4 Map9696.1UniSTS
RH 3.4 Map9696.1RGD
RH 2.0 Map9769.7RGD
Cytogenetic Map9q33UniSTS
RH143383  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2975,676,400 - 75,676,548 (+)MAPPERmRatBN7.2
Rnor_6.0981,374,472 - 81,374,619NCBIRnor6.0
Rnor_5.0981,140,184 - 81,140,331UniSTSRnor5.0
RGSC_v3.4973,417,766 - 73,417,913UniSTSRGSC3.4
Celera973,253,695 - 73,253,842UniSTS
RH 3.4 Map9694.7UniSTS
Cytogenetic Map9q33UniSTS
RH129801  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2975,494,639 - 75,494,856 (+)MAPPERmRatBN7.2
Rnor_6.0981,192,946 - 81,193,162NCBIRnor6.0
Rnor_5.0980,958,970 - 80,959,186UniSTSRnor5.0
RGSC_v3.4973,234,396 - 73,234,612UniSTSRGSC3.4
Celera973,071,481 - 73,071,697UniSTS
RH 3.4 Map9695.4UniSTS
Cytogenetic Map9q33UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 40 29 14 29 8 11 27 35 35 11 8
Low 17 12 5 12 47 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001191810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACYVU010000215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U26310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000035277   ⟹   ENSRNOP00000032812
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl975,495,814 - 75,702,758 (-)Ensembl
Rnor_6.0 Ensembl981,194,119 - 81,400,987 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000096061   ⟹   ENSRNOP00000077508
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl975,495,814 - 75,669,457 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097211   ⟹   ENSRNOP00000091650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl975,495,814 - 75,703,225 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102079   ⟹   ENSRNOP00000096093
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl975,495,814 - 75,676,674 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110496   ⟹   ENSRNOP00000086859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl975,495,814 - 75,615,428 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111419   ⟹   ENSRNOP00000087478
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl975,495,814 - 75,703,225 (-)Ensembl
RefSeq Acc Id: NM_001191810   ⟹   NP_001178739
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,702,851 (-)NCBI
Rnor_6.0981,194,106 - 81,400,987 (-)NCBI
Rnor_5.0980,960,130 - 81,166,699 (-)NCBI
Celera973,072,641 - 73,280,128 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083326   ⟹   XP_038939254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,189 (-)NCBI
RefSeq Acc Id: XM_039083327   ⟹   XP_038939255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,189 (-)NCBI
RefSeq Acc Id: XM_039083328   ⟹   XP_038939256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,189 (-)NCBI
RefSeq Acc Id: XM_039083329   ⟹   XP_038939257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,189 (-)NCBI
RefSeq Acc Id: XM_039083330   ⟹   XP_038939258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,702,853 (-)NCBI
RefSeq Acc Id: XM_039083331   ⟹   XP_038939259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,189 (-)NCBI
RefSeq Acc Id: XM_039083332   ⟹   XP_038939260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,189 (-)NCBI
RefSeq Acc Id: XM_039083333   ⟹   XP_038939261
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,676,726 (-)NCBI
RefSeq Acc Id: XM_039083334   ⟹   XP_038939262
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,189 (-)NCBI
RefSeq Acc Id: XM_039083335   ⟹   XP_038939263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,669,426 (-)NCBI
RefSeq Acc Id: XM_039083336   ⟹   XP_038939264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,702,851 (-)NCBI
RefSeq Acc Id: XM_039083338   ⟹   XP_038939266
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,690 (-)NCBI
RefSeq Acc Id: XM_039083339   ⟹   XP_038939267
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,189 (-)NCBI
RefSeq Acc Id: XM_039083340   ⟹   XP_038939268
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,189 (-)NCBI
RefSeq Acc Id: XM_039083341   ⟹   XP_038939269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,615,415 (-)NCBI
RefSeq Acc Id: XM_039083342   ⟹   XP_038939270
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,050 (-)NCBI
RefSeq Acc Id: XM_039083343   ⟹   XP_038939271
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,657,811 (-)NCBI
RefSeq Acc Id: XM_039083344   ⟹   XP_038939272
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,189 (-)NCBI
RefSeq Acc Id: XM_039083345   ⟹   XP_038939273
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,189 (-)NCBI
RefSeq Acc Id: XM_039083346   ⟹   XP_038939274
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,189 (-)NCBI
RefSeq Acc Id: XM_039083347   ⟹   XP_038939275
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,189 (-)NCBI
RefSeq Acc Id: XM_039083348   ⟹   XP_038939276
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,647,189 (-)NCBI
RefSeq Acc Id: XM_039083349   ⟹   XP_038939277
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,615,414 (-)NCBI
RefSeq Acc Id: XM_039083350   ⟹   XP_038939278
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,580,080 (-)NCBI
RefSeq Acc Id: XM_039083351   ⟹   XP_038939279
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,581,973 (-)NCBI
RefSeq Acc Id: XM_039083352   ⟹   XP_038939280
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,646,972 (-)NCBI
RefSeq Acc Id: XM_039083353   ⟹   XP_038939281
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2975,491,886 - 75,595,341 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001178739 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939254 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939255 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939256 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939257 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939258 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939259 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939260 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939261 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939262 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939263 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939264 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939266 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939267 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939268 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939269 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939270 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939271 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939272 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939273 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939274 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939275 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939276 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939277 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939278 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939279 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939280 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939281 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA67648 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000032812
  ENSRNOP00000032812.6
  ENSRNOP00000077508
  ENSRNOP00000077508.1
  ENSRNOP00000086859
  ENSRNOP00000086859.1
  ENSRNOP00000087478
  ENSRNOP00000087478.1
  ENSRNOP00000091650
  ENSRNOP00000091650.1
  ENSRNOP00000096093.1
RefSeq Acc Id: NP_001178739   ⟸   NM_001191810
- UniProtKB: A0A8I5Y194 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000032812   ⟸   ENSRNOT00000035277
RefSeq Acc Id: XP_038939258   ⟸   XM_039083330
- Peptide Label: isoform X5
- UniProtKB: A0A8I5Y194 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939264   ⟸   XM_039083336
- Peptide Label: isoform X11
- UniProtKB: A0A8I6A4G0 (UniProtKB/TrEMBL),   A0A8I5Y194 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939261   ⟸   XM_039083333
- Peptide Label: isoform X8
- UniProtKB: A0A8I6AQ89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939263   ⟸   XM_039083335
- Peptide Label: isoform X10
- UniProtKB: A0A8I5Y194 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939271   ⟸   XM_039083343
- Peptide Label: isoform X17
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939266   ⟸   XM_039083338
- Peptide Label: isoform X12
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939276   ⟸   XM_039083348
- Peptide Label: isoform X22
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939274   ⟸   XM_039083346
- Peptide Label: isoform X20
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939275   ⟸   XM_039083347
- Peptide Label: isoform X21
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939273   ⟸   XM_039083345
- Peptide Label: isoform X19
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939262   ⟸   XM_039083334
- Peptide Label: isoform X9
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939260   ⟸   XM_039083332
- Peptide Label: isoform X7
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939259   ⟸   XM_039083331
- Peptide Label: isoform X6
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939272   ⟸   XM_039083344
- Peptide Label: isoform X18
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939268   ⟸   XM_039083340
- Peptide Label: isoform X14
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939267   ⟸   XM_039083339
- Peptide Label: isoform X13
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939257   ⟸   XM_039083329
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939255   ⟸   XM_039083327
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939256   ⟸   XM_039083328
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939254   ⟸   XM_039083326
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939270   ⟸   XM_039083342
- Peptide Label: isoform X16
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939280   ⟸   XM_039083352
- Peptide Label: isoform X23
- UniProtKB: F1LN42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939269   ⟸   XM_039083341
- Peptide Label: isoform X15
- UniProtKB: A0A8I6A656 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939277   ⟸   XM_039083349
- Peptide Label: isoform X23
- UniProtKB: F1LN42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939281   ⟸   XM_039083353
- Peptide Label: isoform X23
- UniProtKB: F1LN42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939279   ⟸   XM_039083351
- Peptide Label: isoform X23
- UniProtKB: F1LN42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939278   ⟸   XM_039083350
- Peptide Label: isoform X23
- UniProtKB: F1LN42 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000087478   ⟸   ENSRNOT00000111419
RefSeq Acc Id: ENSRNOP00000096093   ⟸   ENSRNOT00000102079
RefSeq Acc Id: ENSRNOP00000091650   ⟸   ENSRNOT00000097211
RefSeq Acc Id: ENSRNOP00000077508   ⟸   ENSRNOT00000096061
RefSeq Acc Id: ENSRNOP00000086859   ⟸   ENSRNOT00000110496
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LN42-F1-model_v2 AlphaFold F1LN42 1-1909 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68427 AgrOrtholog
BioCyc Gene G2FUF-27152 BioCyc
Ensembl Genes ENSRNOG00000014182 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000035277 ENTREZGENE
  ENSRNOT00000035277.6 UniProtKB/TrEMBL
  ENSRNOT00000096061 ENTREZGENE
  ENSRNOT00000096061.1 UniProtKB/TrEMBL
  ENSRNOT00000097211 ENTREZGENE
  ENSRNOT00000097211.1 UniProtKB/TrEMBL
  ENSRNOT00000102079.1 UniProtKB/TrEMBL
  ENSRNOT00000110496 ENTREZGENE
  ENSRNOT00000110496.1 UniProtKB/TrEMBL
  ENSRNOT00000111419 ENTREZGENE
  ENSRNOT00000111419.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  2.60.40.1110 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  PH_like_dom UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Prot_Kinase_C-like_PE/DAG-bd UniProtKB/TrEMBL
  PTB UniProtKB/TrEMBL
  PTyr_interaction_dom UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  Tensin_like_SH2 UniProtKB/TrEMBL
  Tensin_lipid_phosphatase_dom UniProtKB/TrEMBL
  Tensin_phosphatase_C2-dom UniProtKB/TrEMBL
  Tensin_PTB UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
NCBI Gene 301509 ENTREZGENE
PANTHER TENSIN UniProtKB/TrEMBL
  TENSIN-1 UniProtKB/TrEMBL
Pfam PTB UniProtKB/TrEMBL
  PTEN_C2 UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
PhenoGen Tns1 PhenoGen
PROSITE C2_TENSIN UniProtKB/TrEMBL
  PPASE_TENSIN UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014182 RatGTEx
SMART PTB UniProtKB/TrEMBL
  PTEN_C2 UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A8I5Y194 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A4G0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A656 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AFL2_RAT UniProtKB/TrEMBL
  A0A8I6AQ89 ENTREZGENE, UniProtKB/TrEMBL
  F1LN42 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-05-05 Tns1  tensin 1  LOC301509  similar to tensin  Data merged from RGD:1583849 737654 APPROVED
2008-02-18 Tns1  tensin 1  Tns  tensin  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC301509  similar to tensin      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Tns  tensin      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference