Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Slc11a1 (solute carrier family 11 member 1) Rattus norvegicus
Symbol: Slc11a1
Name: solute carrier family 11 member 1
Description: Predicted to have metal ion transmembrane transporter activity and protein homodimerization activity. Predicted to be involved in several processes, including cation transport; defense response to other organism; and inorganic ion homeostasis. Predicted to localize to cytoplasmic vesicle; lysosome; and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hypersensitivity disease (multiple); inflammatory bowel disease (multiple); leishmaniasis (multiple); rheumatoid arthritis (multiple); and tuberculosis (multiple). Orthologous to human SLC11A1 (solute carrier family 11 member 1); INTERACTS WITH acetamide; ammonium chloride; bisphenol A.
Type: protein-coding
Also known as: Bcg; Itg; Lsh; MGC124692; natural resistance associated macrophage protein 1; natural resistance-associated macrophage protein 1; NRAMP 1; Nramp1; solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
Homo sapiens (human) : SLC11A1 (solute carrier family 11 member 1)  HGNC  Alliance
Mus musculus (house mouse) : Slc11a1 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc11a1 (solute carrier family 11 member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC11A1 (solute carrier family 11 member 1)
Canis lupus familiaris (dog) : SLC11A1 (solute carrier family 11 member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc11a1 (solute carrier family 11 member 1)
Sus scrofa (pig) : SLC11A1 (solute carrier family 11 member 1)
Heterocephalus glaber (naked mole-rat) : Slc11a1 (solute carrier family 11 member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0981,655,590 - 81,666,697 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl981,655,629 - 81,666,706 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0981,420,556 - 81,431,345 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,714,692 - 73,725,523 (+)NCBIRGSC3.4rn4RGSC3.4
Celera973,531,012 - 73,541,597 (+)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Slc11a1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1601463
Created: 2007-04-21
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.