Gene: Slc11a1 (solute carrier family 11 member 1) Rattus norvegicus
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Symbol: Slc11a1
Name: solute carrier family 11 member 1
Description: ENCODES a protein that exhibits manganese ion transmembrane transporter activity (ortholog); metal ion:proton antiporter activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); antigen processing and presentation of peptide antigen (ortholog); cadmium ion transmembrane transport (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); asthma (ortholog); atopic dermatitis (ortholog); FOUND IN endosome membrane (ortholog); late endosome (ortholog); lysosome (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; D-penicillamine
AGR Description: Predicted to have protein homodimerization activity and transmembrane transporter activity; predicted to be involved in several processes, including cation transport, defense response to other organism, and ion homeostasis; predicted to localize to the cytoplasm, intracellular organelle, and plasma membrane; orthologous to human SLC11A1 (solute carrier family 11 member 1).
Merged Description: Predicted to have protein homodimerization activity and transmembrane transporter activity; predicted to be involved in several processes, including cation transport, defense response to other organism, and ion homeostasis; predicted to localize to the cytoplasm, intracellular organelle, and plasma membrane; orthologous to human SLC11A1 (solute carrier family 11 member 1); INTERACTS WITH ammonium chloride; bisphenol A; D-penicillamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Bcg; Itg; Lsh; MGC124692; natural resistance associated macrophage protein 1; natural resistance-associated macrophage protein 1; NRAMP 1; Nramp1; solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
Orthologs:
Homo sapiens (human) : SLC11A1 (solute carrier family 11 member 1)  HGNC  Alliance
Mus musculus (house mouse) : Slc11a1 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc11a1 (solute carrier family 11 member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC11A1 (solute carrier family 11 member 1)
Canis lupus familiaris (dog) : SLC11A1 (solute carrier family 11 member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc11a1 (solute carrier family 11 member 1)
Sus scrofa (pig) : SLC11A1 (solute carrier family 11 member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0981,655,590 - 81,666,697 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0981,420,556 - 81,431,345 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,714,692 - 73,725,523 (+)NCBIRGSC3.4rn4RGSC3.4
Celera973,531,012 - 73,541,597 (+)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Slc11a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1601463
Created: 2007-04-21
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.