Asic4 (acid sensing ion channel subunit family member 4) - Rat Genome Database

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Gene: Asic4 (acid sensing ion channel subunit family member 4) Rattus norvegicus
Analyze
Symbol: Asic4
Name: acid sensing ion channel subunit family member 4
RGD ID: 621068
Description: Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to act upstream of or within behavioral fear response. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human ASIC4 (acid sensing ion channel subunit family member 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ACCN4; acid sensing ion channel 4; acid-sensing (proton-gated) ion channel family member 4; acid-sensing ion channel 4; amiloride-sensitive cation channel 4; amiloride-sensitive cation channel 4, pituitary; putative acid-sensing ion channel; Spasic; spinal chord ASIC; spinal cord ASIC
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2976,941,532 - 76,962,900 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl976,941,532 - 76,962,900 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx985,385,842 - 85,407,158 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0990,514,723 - 90,536,037 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0988,900,898 - 88,922,216 (+)NCBIRnor_WKY
Rnor_6.0982,647,071 - 82,668,920 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl982,647,071 - 82,668,920 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0982,412,948 - 82,438,181 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4974,728,291 - 74,749,661 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1974,875,294 - 74,896,710 (+)NCBI
Celera974,511,463 - 74,532,798 (+)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. A new member of acid-sensing ion channels from pituitary gland. Grunder S, etal., Neuroreport 2000 Jun 5;11(8):1607-11.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10923674   PMID:16085050   PMID:25828470  


Genomics

Comparative Map Data
Asic4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2976,941,532 - 76,962,900 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl976,941,532 - 76,962,900 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx985,385,842 - 85,407,158 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0990,514,723 - 90,536,037 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0988,900,898 - 88,922,216 (+)NCBIRnor_WKY
Rnor_6.0982,647,071 - 82,668,920 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl982,647,071 - 82,668,920 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0982,412,948 - 82,438,181 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4974,728,291 - 74,749,661 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1974,875,294 - 74,896,710 (+)NCBI
Celera974,511,463 - 74,532,798 (+)NCBICelera
Cytogenetic Map9q33NCBI
ASIC4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,507,093 - 219,538,772 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2219,514,170 - 219,538,772 (+)EnsemblGRCh38hg38GRCh38
GRCh372220,379,204 - 220,403,494 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,087,296 - 220,111,738 (+)NCBINCBI36Build 36hg18NCBI36
Celera2214,148,884 - 214,173,457 (+)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2212,231,962 - 212,256,523 (+)NCBIHuRef
CHM1_12220,384,734 - 220,409,316 (+)NCBICHM1_1
T2T-CHM13v2.02219,999,227 - 220,023,471 (+)NCBIT2T-CHM13v2.0
Asic4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39175,426,467 - 75,450,984 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl175,427,080 - 75,450,987 (+)EnsemblGRCm39 Ensembl
GRCm38175,450,510 - 75,474,340 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl175,450,436 - 75,474,343 (+)EnsemblGRCm38mm10GRCm38
MGSCv37175,447,085 - 75,470,915 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36175,333,847 - 75,357,488 (+)NCBIMGSCv36mm8
Celera175,941,575 - 75,963,693 (+)NCBICelera
Cytogenetic Map1C4NCBI
Asic4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545313,935,826 - 13,961,664 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545313,937,745 - 13,961,664 (-)NCBIChiLan1.0ChiLan1.0
ASIC4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B225,361,131 - 225,386,087 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B225,361,477 - 225,386,081 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B106,770,714 - 106,796,044 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ASIC4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13726,024,136 - 26,048,060 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3726,024,947 - 26,048,077 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3726,849,461 - 26,873,031 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03726,039,062 - 26,062,668 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3726,039,987 - 26,063,158 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13725,942,213 - 25,966,226 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03725,879,090 - 25,902,650 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03725,899,663 - 25,923,239 (+)NCBIUU_Cfam_GSD_1.0
Asic4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303175,553,612 - 175,576,041 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365691,896,395 - 1,918,847 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365691,894,631 - 1,918,822 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASIC4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15121,522,550 - 121,547,497 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115121,520,003 - 121,547,520 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215134,594,197 - 134,626,509 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ASIC4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110105,406,889 - 105,433,792 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604093,967,447 - 93,992,202 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Asic4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248235,523,185 - 5,544,956 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248235,523,166 - 5,544,982 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Asic4
72 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:384
Count of miRNA genes:205
Interacting mature miRNAs:244
Transcripts:ENSRNOT00000027135
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95584784177026453Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95662771378595166Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)95662771378595166Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)95662771378595166Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat

Markers in Region
D9Mco53  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2976,943,526 - 76,943,723 (+)MAPPERmRatBN7.2
Rnor_6.0982,649,066 - 82,649,262NCBIRnor6.0
Rnor_5.0982,418,327 - 82,418,523UniSTSRnor5.0
RGSC_v3.4974,730,286 - 74,730,482UniSTSRGSC3.4
Celera974,513,458 - 74,513,654UniSTS
Cytogenetic Map9q33UniSTS
D9Mco55  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2976,962,850 - 76,963,043 (+)MAPPERmRatBN7.2
Rnor_6.0982,668,871 - 82,669,063NCBIRnor6.0
Rnor_5.0982,438,132 - 82,438,324UniSTSRnor5.0
RGSC_v3.4974,749,612 - 74,749,804UniSTSRGSC3.4
Celera974,532,749 - 74,532,941UniSTS
Cytogenetic Map9q33UniSTS
D9Mco54  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2976,949,699 - 76,949,885 (+)MAPPERmRatBN7.2
Rnor_6.0982,655,239 - 82,655,426NCBIRnor6.0
Rnor_5.0982,424,500 - 82,424,687UniSTSRnor5.0
RGSC_v3.4974,736,459 - 74,736,646UniSTSRGSC3.4
Celera974,519,634 - 74,519,816UniSTS
Cytogenetic Map9q33UniSTS
stSG633055  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2976,941,889 - 76,943,117 (+)MAPPERmRatBN7.2
Rnor_6.0982,647,429 - 82,648,656NCBIRnor6.0
Rnor_5.0982,416,690 - 82,417,917UniSTSRnor5.0
RGSC_v3.4974,728,649 - 74,729,876UniSTSRGSC3.4
Celera974,511,821 - 74,513,048UniSTS
Cytogenetic Map9q33UniSTS
ECD06448  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2976,942,410 - 76,943,117 (+)MAPPERmRatBN7.2
Rnor_6.0982,647,950 - 82,648,656NCBIRnor6.0
Rnor_5.0982,417,211 - 82,417,917UniSTSRnor5.0
RGSC_v3.4974,729,170 - 74,729,876UniSTSRGSC3.4
Celera974,512,342 - 74,513,048UniSTS
Cytogenetic Map9q33UniSTS
REN53167  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2976,941,863 - 76,942,133 (+)MAPPERmRatBN7.2
Rnor_6.0982,647,403 - 82,647,672NCBIRnor6.0
Rnor_5.0982,416,664 - 82,416,933UniSTSRnor5.0
RGSC_v3.4974,728,623 - 74,728,892UniSTSRGSC3.4
Celera974,511,795 - 74,512,064UniSTS
Cytogenetic Map9q33UniSTS
REN53166  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2976,941,659 - 76,941,910 (+)MAPPERmRatBN7.2
Rnor_6.0982,647,199 - 82,647,449NCBIRnor6.0
Rnor_5.0982,416,460 - 82,416,710UniSTSRnor5.0
RGSC_v3.4974,728,419 - 74,728,669UniSTSRGSC3.4
Celera974,511,591 - 74,511,841UniSTS
Cytogenetic Map9q33UniSTS
REN53165  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2976,941,410 - 76,941,679 (+)MAPPERmRatBN7.2
Rnor_6.0982,646,950 - 82,647,218NCBIRnor6.0
Rnor_5.0982,416,211 - 82,416,479UniSTSRnor5.0
RGSC_v3.4974,728,170 - 74,728,438UniSTSRGSC3.4
Celera974,511,342 - 74,511,610UniSTS
Cytogenetic Map9q33UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 39 3
Low 1 12 14 6 1 6 35 19 35 4
Below cutoff 2 25 28 20 18 20 5 7 16 3 7 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000027135   ⟹   ENSRNOP00000027135
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl976,941,532 - 76,962,900 (+)Ensembl
Rnor_6.0 Ensembl982,647,071 - 82,668,920 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101375   ⟹   ENSRNOP00000094476
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl976,941,532 - 76,962,900 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102212   ⟹   ENSRNOP00000081247
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl976,941,532 - 76,962,900 (+)Ensembl
RefSeq Acc Id: NM_022234   ⟹   NP_071570
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2976,941,532 - 76,962,900 (+)NCBI
Rnor_6.0982,647,071 - 82,668,920 (+)NCBI
Rnor_5.0982,412,948 - 82,438,181 (+)NCBI
RGSC_v3.4974,728,291 - 74,749,661 (+)RGD
Celera974,511,463 - 74,532,798 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_071570 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAB61836 (Get FASTA)   NCBI Sequence Viewer  
  CAB93984 (Get FASTA)   NCBI Sequence Viewer  
  EDL75443 (Get FASTA)   NCBI Sequence Viewer  
  EDL75444 (Get FASTA)   NCBI Sequence Viewer  
  Q9JHS6 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_071570   ⟸   NM_022234
- UniProtKB: Q9JHS6 (UniProtKB/Swiss-Prot),   G3V8N2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000027135   ⟸   ENSRNOT00000027135
RefSeq Acc Id: ENSRNOP00000081247   ⟸   ENSRNOT00000102212
RefSeq Acc Id: ENSRNOP00000094476   ⟸   ENSRNOT00000101375

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JHS6-F1-model_v2 AlphaFold Q9JHS6 1-539 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621068 AgrOrtholog
BioCyc Gene G2FUF-27066 BioCyc
Ensembl Genes ENSRNOG00000019985 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000027135 ENTREZGENE
  ENSRNOP00000027135.3 UniProtKB/TrEMBL
  ENSRNOP00000081247.1 UniProtKB/TrEMBL
  ENSRNOP00000094476.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000027135 ENTREZGENE
  ENSRNOT00000027135.5 UniProtKB/TrEMBL
  ENSRNOT00000101375.1 UniProtKB/TrEMBL
  ENSRNOT00000102212.1 UniProtKB/TrEMBL
InterPro ENaC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENaC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:63882 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 63882 ENTREZGENE
PANTHER PTHR11690 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ASC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Asic4 PhenoGen
PRINTS AMINACHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ASC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZSF3_RAT UniProtKB/TrEMBL
  A0A8I6AKV8_RAT UniProtKB/TrEMBL
  ASIC4_RAT UniProtKB/Swiss-Prot
  G3V8N2 ENTREZGENE, UniProtKB/TrEMBL
  Q9JHS6 ENTREZGENE
UniProt Secondary Q9QYV9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-12-13 Asic4  acid sensing ion channel subunit family member 4  Asic4  acid sensing ion channel 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-12-09 Asic4  acid sensing ion channel 4  Asic4  acid-sensing (proton-gated) ion channel family member 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-13 Asic4  acid-sensing (proton-gated) ion channel family member 4  Accn4  amiloride-sensitive cation channel 4, pituitary  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Accn4  amiloride-sensitive cation channel 4, pituitary  Asic4  SPASIC protein  Symbol and Name updated 1299863 APPROVED
2002-08-07 Asic4  SPASIC protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression strongest expression in pituitary gland; also expressed in throughout brain, in the spinal cord, and inner ear 632227