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Gene: Fam117b (family with sequence similarity 117, member B) Rattus norvegicus

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Symbol:

Fam117b

Name:

family with sequence similarity 117, member B

RGD ID:

1307676

Description:

Orthologous to human FAM117B (family with sequence similarity 117 member B); INTERACTS WITH 17beta-estradiol; 2,3,4,7,8-Pentachlorodibenzofuran; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Als2cr13; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 13; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 13 (human); LOC363236

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	68,834,334 - 68,902,543 (+)	NCBI		GRCr8
mRatBN7.2	9	61,340,284 - 61,418,531 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	61,340,249 - 61,408,483 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	69,840,399 - 69,908,549 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	74,955,951 - 75,024,103 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	73,274,661 - 73,342,815 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	66,716,969 - 66,784,487 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	66,716,969 - 66,784,487 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	66,520,071 - 66,596,356 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	58,476,287 - 58,544,228 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	58,622,696 - 58,688,285 (+)	NCBI
Celera	9	58,775,417 - 58,842,774 (+)	NCBI		Celera
Cytogenetic Map	9	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Imported Disease Annotations - ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Fam117b	Rat	autoimmune lymphoproliferative syndrome type 2B		ISO	RGD:1317004	8554872	ClinVar Annotator: match by term: Autoimmune lymphoproliferative syndrome type 2B	ClinVar	PMID:11343122\|PMID:12353035\|PMID:12577056\|PMID:19380800\|PMID:25213377\|PMID:25329329\|PMID:25814141\|PMID:28492532\|PMID:29729943\|PMID:30326257
Fam117b	Rat	Autoimmune Lymphoproliferative Syndrome, Type V		ISO	RGD:1317004	8554872	ClinVar Annotator: match by term: Autoimmune lymphoproliferative syndrome type V	ClinVar	PMID:11343122\|PMID:12353035\|PMID:12577056\|PMID:19380800\|PMID:25213377\|PMID:25329329\|PMID:25814141\|PMID:28492532\|PMID:29729943\|PMID:30326257
Fam117b	Rat	common variable immunodeficiency 1		ISO	RGD:1317004	8554872	ClinVar Annotator: match by term: Immunodeficiency, common variable, 1	ClinVar	PMID:11343122\|PMID:12353035\|PMID:12577056\|PMID:19380800\|PMID:25213377\|PMID:25329329\|PMID:25814141\|PMID:28492532\|PMID:29729943\|PMID:30326257
Fam117b	Rat	Neurodevelopmental Disorders		ISO	RGD:1317004	8554872	ClinVar Annotator: match by term: Neurodevelopmental disorder	ClinVar	PMID:25741868
Fam117b	Rat	primary pulmonary hypertension		ISO	RGD:1317004	8554872	ClinVar Annotator: match by term: Primary pulmonary hypertension	ClinVar	PMID:28492532\|PMID:31727138
Fam117b	Rat	Pulmonary Arterial Hypertension		ISO	RGD:1317004	8554872	ClinVar Annotator: match by term: Pulmonary arterial hypertension	ClinVar	PMID:32581362

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Fam117b	Rat	1,2-dimethylhydrazine	multiple interactions	ISO	RGD:1614310	6480464	[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FAM117B mRNA	CTD	PMID:22206623
Fam117b	Rat	1,2-dimethylhydrazine	affects expression	ISO	RGD:1614310	6480464	1,2-Dimethylhydrazine affects the expression of FAM117B mRNA	CTD	PMID:22206623
Fam117b	Rat	17beta-estradiol	decreases expression	EXP		6480464	Estradiol results in decreased expression of FAM117B mRNA	CTD	PMID:32145629
Fam117b	Rat	2,3',4,4',5-Pentachlorobiphenyl	increases expression	ISO	RGD:1614310	6480464	2,3',4,4',5-pentachlorobiphenyl results in increased expression of FAM117B mRNA	CTD	PMID:31388691
Fam117b	Rat	2,3,4,7,8-Pentachlorodibenzofuran	decreases expression	EXP		6480464	2,3,4,7,8-pentachlorodibenzofuran results in decreased expression of FAM117B mRNA	CTD	PMID:21724226
Fam117b	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	RGD:1614310	6480464	Tetrachlorodibenzodioxin results in decreased expression of FAM117B mRNA	CTD	PMID:19770486
Fam117b	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of FAM117B mRNA	CTD	PMID:34747641
Fam117b	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of FAM117B mRNA	CTD	PMID:21215274\|PMID:21724226\|PMID:33387578
Fam117b	Rat	2,3,7,8-Tetrachlorodibenzofuran	decreases expression	EXP		6480464	2,3,7,8-tetrachlorodibenzofuran results in decreased expression of FAM117B mRNA	CTD	PMID:21724226
Fam117b	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	RGD:1614310	6480464	bisphenol S results in decreased expression of FAM117B mRNA	CTD	PMID:33297965
Fam117b	Rat	4-hydroxyphenyl retinamide	decreases expression	ISO	RGD:1614310	6480464	Fenretinide results in decreased expression of FAM117B mRNA	CTD	PMID:28973697
Fam117b	Rat	6-propyl-2-thiouracil	decreases expression	EXP		6480464	Propylthiouracil results in decreased expression of FAM117B mRNA	CTD	PMID:30047161
Fam117b	Rat	acrylamide	increases expression	EXP		6480464	Acrylamide results in increased expression of FAM117B mRNA	CTD	PMID:28959563
Fam117b	Rat	all-trans-retinoic acid	decreases expression	ISO	RGD:1317004	6480464	Tretinoin results in decreased expression of FAM117B mRNA	CTD	PMID:33167477
Fam117b	Rat	amitrole	decreases expression	EXP		6480464	Amitrole results in decreased expression of FAM117B mRNA	CTD	PMID:30047161
Fam117b	Rat	amphetamine	decreases expression	EXP		6480464	Amphetamine results in decreased expression of FAM117B mRNA	CTD	PMID:30779732
Fam117b	Rat	aristolochic acid A	decreases expression	ISO	RGD:1317004	6480464	aristolochic acid I results in decreased expression of FAM117B mRNA	CTD	PMID:33212167
Fam117b	Rat	arsane	affects expression	ISO	RGD:1317004	6480464	Arsenic affects the expression of FAM117B mRNA	CTD	PMID:18414638
Fam117b	Rat	arsane	multiple interactions	ISO	RGD:1317004	6480464	[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of FAM117B more ...	CTD	PMID:39836092
Fam117b	Rat	arsenic atom	affects expression	ISO	RGD:1317004	6480464	Arsenic affects the expression of FAM117B mRNA	CTD	PMID:18414638
Fam117b	Rat	arsenic atom	multiple interactions	ISO	RGD:1317004	6480464	[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of FAM117B more ...	CTD	PMID:39836092
Fam117b	Rat	arsenous acid	increases expression	ISO	RGD:1317004	6480464	Arsenic Trioxide results in increased expression of FAM117B mRNA	CTD	PMID:20458559
Fam117b	Rat	benzo[a]pyrene	increases expression	ISO	RGD:1614310	6480464	Benzo(a)pyrene results in increased expression of FAM117B mRNA	CTD	PMID:21569818
Fam117b	Rat	benzo[a]pyrene	decreases methylation	ISO	RGD:1317004	6480464	Benzo(a)pyrene results in decreased methylation of FAM117B promoter	CTD	PMID:27901495
Fam117b	Rat	benzo[a]pyrene	decreases expression	ISO	RGD:1614310	6480464	Benzo(a)pyrene results in decreased expression of FAM117B mRNA	CTD	PMID:22228805
Fam117b	Rat	benzo[a]pyrene diol epoxide I	increases expression	ISO	RGD:1317004	6480464	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of FAM117B mRNA	CTD	PMID:26238291
Fam117b	Rat	bis(2-ethylhexyl) phthalate	increases expression	ISO	RGD:1317004	6480464	Diethylhexyl Phthalate results in increased expression of FAM117B protein	CTD	PMID:31163220
Fam117b	Rat	bis(2-ethylhexyl) phthalate	decreases expression	ISO	RGD:1614310	6480464	Diethylhexyl Phthalate results in decreased expression of FAM117B mRNA	CTD	PMID:33754040
Fam117b	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of FAM117B mRNA	CTD	PMID:25181051\|PMID:30816183\|PMID:33296240\|PMID:34947998
Fam117b	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of FAM117B mRNA	CTD	PMID:32145629
Fam117b	Rat	bisphenol F	increases expression	ISO	RGD:1614310	6480464	bisphenol F results in increased expression of FAM117B mRNA	CTD	PMID:38685157
Fam117b	Rat	cadmium atom	multiple interactions	ISO	RGD:1317004	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of FAM117B more ...	CTD	PMID:35301059
Fam117b	Rat	cadmium dichloride	multiple interactions	ISO	RGD:1317004	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of FAM117B more ...	CTD	PMID:35301059
Fam117b	Rat	caffeine	increases phosphorylation	ISO	RGD:1317004	6480464	Caffeine results in increased phosphorylation of FAM117B protein	CTD	PMID:35688186
Fam117b	Rat	carbon nanotube	decreases expression	ISO	RGD:1614310	6480464	Nanotubes, Carbon analog results in decreased expression of FAM117B mRNA; Nanotubes, Carbon results in decreased more ...	CTD	PMID:25554681
Fam117b	Rat	cisplatin	decreases expression	ISO	RGD:1317004	6480464	Cisplatin results in decreased expression of FAM117B mRNA	CTD	PMID:27594783
Fam117b	Rat	coumarin	increases phosphorylation	ISO	RGD:1317004	6480464	coumarin results in increased phosphorylation of FAM117B protein	CTD	PMID:35688186
Fam117b	Rat	cyclosporin A	decreases expression	ISO	RGD:1317004	6480464	Cyclosporine results in decreased expression of FAM117B mRNA	CTD	PMID:20106945
Fam117b	Rat	cyclosporin A	decreases expression	ISO	RGD:1614310	6480464	Cyclosporine results in decreased expression of FAM117B mRNA	CTD	PMID:19770486
Fam117b	Rat	diarsenic trioxide	increases expression	ISO	RGD:1317004	6480464	Arsenic Trioxide results in increased expression of FAM117B mRNA	CTD	PMID:20458559
Fam117b	Rat	dioxygen	increases expression	ISO	RGD:1317004	6480464	Oxygen deficiency results in increased expression of FAM117B mRNA	CTD	PMID:26516004
Fam117b	Rat	dorsomorphin	multiple interactions	ISO	RGD:1317004	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Fam117b	Rat	doxorubicin	decreases expression	ISO	RGD:1317004	6480464	Doxorubicin results in decreased expression of FAM117B mRNA	CTD	PMID:29803840
Fam117b	Rat	endosulfan	decreases expression	EXP		6480464	Endosulfan results in decreased expression of FAM117B mRNA	CTD	PMID:29391264
Fam117b	Rat	ethanol	affects splicing	ISO	RGD:1614310	6480464	Ethanol affects the splicing of FAM117B mRNA	CTD	PMID:30319688
Fam117b	Rat	ethyl methanesulfonate	decreases expression	ISO	RGD:1317004	6480464	Ethyl Methanesulfonate results in decreased expression of FAM117B mRNA	CTD	PMID:23649840
Fam117b	Rat	flutamide	decreases expression	EXP		6480464	Flutamide results in decreased expression of FAM117B mRNA	CTD	PMID:24136188
Fam117b	Rat	folic acid	multiple interactions	ISO	RGD:1614310	6480464	[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FAM117B mRNA	CTD	PMID:22206623
Fam117b	Rat	formaldehyde	decreases expression	ISO	RGD:1317004	6480464	Formaldehyde results in decreased expression of FAM117B mRNA	CTD	PMID:23649840
Fam117b	Rat	FR900359	affects phosphorylation	ISO	RGD:1317004	6480464	FR900359 affects the phosphorylation of FAM117B protein	CTD	PMID:37730182
Fam117b	Rat	gentamycin	decreases expression	EXP		6480464	Gentamicins results in decreased expression of FAM117B mRNA	CTD	PMID:33387578
Fam117b	Rat	glafenine	decreases expression	EXP		6480464	Glafenine results in decreased expression of FAM117B mRNA	CTD	PMID:24136188
Fam117b	Rat	hexadecanoic acid	decreases phosphorylation	ISO	RGD:1317004	6480464	Palmitic Acid results in decreased phosphorylation of FAM117B protein	CTD	PMID:28073184
Fam117b	Rat	hydrogen cyanide	increases expression	ISO	RGD:1614310	6480464	Hydrogen Cyanide results in increased expression of FAM117B mRNA	CTD	PMID:33914522
Fam117b	Rat	hydroquinone	decreases expression	ISO	RGD:1317004	6480464	hydroquinone results in decreased expression of FAM117B mRNA	CTD	PMID:31256213
Fam117b	Rat	iron atom	increases expression	EXP		6480464	Iron deficiency results in increased expression of FAM117B mRNA	CTD	PMID:16629162
Fam117b	Rat	iron(0)	increases expression	EXP		6480464	Iron deficiency results in increased expression of FAM117B mRNA	CTD	PMID:16629162
Fam117b	Rat	isoprenaline	increases expression	ISO	RGD:1614310	6480464	Isoproterenol results in increased expression of FAM117B mRNA	CTD	PMID:20003209
Fam117b	Rat	methapyrilene	decreases expression	EXP		6480464	Methapyrilene results in decreased expression of FAM117B mRNA	CTD	PMID:30467583
Fam117b	Rat	methimazole	decreases expression	EXP		6480464	Methimazole results in decreased expression of FAM117B mRNA	CTD	PMID:30047161
Fam117b	Rat	methyl methanesulfonate	decreases expression	ISO	RGD:1317004	6480464	Methyl Methanesulfonate results in decreased expression of FAM117B mRNA	CTD	PMID:23649840
Fam117b	Rat	methylmercury chloride	increases expression	ISO	RGD:1317004	6480464	methylmercuric chloride results in increased expression of FAM117B mRNA	CTD	PMID:28001369
Fam117b	Rat	nefazodone	decreases expression	EXP		6480464	nefazodone results in decreased expression of FAM117B mRNA	CTD	PMID:24136188
Fam117b	Rat	nickel sulfate	increases expression	ISO	RGD:1317004	6480464	nickel sulfate results in increased expression of FAM117B mRNA	CTD	PMID:22714537
Fam117b	Rat	ozone	multiple interactions	ISO	RGD:1614310	6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ...	CTD	PMID:34911549
Fam117b	Rat	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of FAM117B mRNA	CTD	PMID:33387578
Fam117b	Rat	phenformin	increases expression	EXP		6480464	Phenformin results in increased expression of FAM117B mRNA	CTD	PMID:31324951
Fam117b	Rat	phenobarbital	decreases expression	EXP		6480464	Phenobarbital results in decreased expression of FAM117B mRNA	CTD	PMID:30047161
Fam117b	Rat	phenylmercury acetate	decreases expression	ISO	RGD:1317004	6480464	Phenylmercuric Acetate results in decreased expression of FAM117B mRNA	CTD	PMID:26272509
Fam117b	Rat	phenylmercury acetate	multiple interactions	ISO	RGD:1317004	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Fam117b	Rat	potassium cyanide	increases expression	ISO	RGD:1614310	6480464	Potassium Cyanide results in increased expression of FAM117B mRNA	CTD	PMID:33914522
Fam117b	Rat	quercetin	decreases expression	ISO	RGD:1317004	6480464	Quercetin results in decreased expression of FAM117B mRNA	CTD	PMID:21632981
Fam117b	Rat	SB 431542	multiple interactions	ISO	RGD:1317004	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Fam117b	Rat	silver atom	decreases expression	ISO	RGD:1614310	6480464	Silver results in decreased expression of FAM117B mRNA	CTD	PMID:27131904
Fam117b	Rat	silver(0)	decreases expression	ISO	RGD:1614310	6480464	Silver results in decreased expression of FAM117B mRNA	CTD	PMID:27131904
Fam117b	Rat	sodium arsenite	multiple interactions	ISO	RGD:1317004	6480464	[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of FAM117B more ...	CTD	PMID:39836092
Fam117b	Rat	sulfadimethoxine	decreases expression	EXP		6480464	Sulfadimethoxine results in decreased expression of FAM117B mRNA	CTD	PMID:30047161
Fam117b	Rat	sunitinib	increases expression	ISO	RGD:1317004	6480464	Sunitinib results in increased expression of FAM117B mRNA	CTD	PMID:31533062
Fam117b	Rat	tetrachloromethane	increases expression	ISO	RGD:1614310	6480464	Carbon Tetrachloride results in increased expression of FAM117B mRNA	CTD	PMID:31919559
Fam117b	Rat	thioacetamide	decreases expression	EXP		6480464	Thioacetamide results in decreased expression of FAM117B mRNA	CTD	PMID:34492290
Fam117b	Rat	thiram	decreases expression	ISO	RGD:1317004	6480464	Thiram results in decreased expression of FAM117B mRNA	CTD	PMID:38568856
Fam117b	Rat	titanium dioxide	decreases expression	ISO	RGD:1614310	6480464	titanium dioxide results in decreased expression of FAM117B mRNA	CTD	PMID:29264374
Fam117b	Rat	titanium dioxide	increases methylation	ISO	RGD:1614310	6480464	titanium dioxide results in increased methylation of FAM117B promoter	CTD	PMID:35295148
Fam117b	Rat	titanium dioxide	decreases methylation	ISO	RGD:1614310	6480464	titanium dioxide results in decreased methylation of FAM117B gene	CTD	PMID:35295148
Fam117b	Rat	trichloroethene	decreases expression	EXP		6480464	Trichloroethylene results in decreased expression of FAM117B mRNA	CTD	PMID:33387578
Fam117b	Rat	triphenyl phosphate	increases expression	EXP		6480464	triphenyl phosphate results in increased expression of FAM117B mRNA	CTD	PMID:30589522
Fam117b	Rat	urethane	increases expression	ISO	RGD:1317004	6480464	Urethane results in increased expression of FAM117B mRNA	CTD	PMID:28818685
Fam117b	Rat	valdecoxib	decreases expression	EXP		6480464	valdecoxib results in decreased expression of FAM117B mRNA	CTD	PMID:24136188
Fam117b	Rat	valproic acid	increases methylation	ISO	RGD:1317004	6480464	Valproic Acid results in increased methylation of FAM117B gene	CTD	PMID:29154799
Fam117b	Rat	valproic acid	decreases expression	ISO	RGD:1317004	6480464	Valproic Acid results in decreased expression of FAM117B mRNA	CTD	PMID:23179753
Fam117b	Rat	valproic acid	affects expression	ISO	RGD:1317004	6480464	Valproic Acid affects the expression of FAM117B mRNA	CTD	PMID:25979313

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Fam117b	Rat	protein binding	enables	ISO	RGD:1317004	1624291	UniProtKB:O14901\|UniProtKB:O60260-5\|UniProtKB:O60333-2\|UniProtKB:O75190\|UniProtKB:O76024\|UniProtKB:O95994\|UniProtKB:P04792\|UniProtKB:P21333-2\|UniProtKB:P24539\|UniProtKB:P31153\|UniProtKB:P31947\|UniProtKB:P46379-2\|UniProtKB:P60891\|UniProtKB:P63167\|UniProtKB:P78333\|UniProtKB:Q01658\|UniProtKB:Q13148\|UniProtKB:Q14145\|UniProtKB:Q8N2W9\|UniProtKB:Q8N9N5\|UniProtKB:Q8N9N5-2\|UniProtKB:Q96FJ2\|UniProtKB:Q9UMF0\|UniProtKB:Q9Y3C5\|UniProtKB:Q9Y5Q9 PMID:15778465, PMID:25416956, PMID:26496610, PMID:27173435, PMID:28514442, PMID:31515488, PMID:32296183, PMID:32814053, PMID:33961781, PMID:35271311, PMID:36931259	RGD	PMID:15778465\|PMID:25416956\|PMID:26496610\|PMID:27173435\|PMID:28514442\|PMID:31515488\|PMID:32296183\|PMID:32814053\|PMID:33961781\|PMID:35271311\|PMID:36931259

Disease Annotations Click to see Annotation Detail View

autoimmune lymphoproliferative syndrome type 2B (ISO)

Autoimmune Lymphoproliferative Syndrome, Type V (ISO)

common variable immunodeficiency 1 (ISO)

Neurodevelopmental Disorders (ISO)

primary pulmonary hypertension (ISO)

Pulmonary Arterial Hypertension (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,4,7,8-Pentachlorodibenzofuran (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

all-trans-retinoic acid (ISO)

amitrole (EXP)

amphetamine (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

carbon nanotube (ISO)

cisplatin (ISO)

coumarin (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

ethyl methanesulfonate (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

gentamycin (EXP)

glafenine (EXP)

hexadecanoic acid (ISO)

hydrogen cyanide (ISO)

hydroquinone (ISO)

iron atom (EXP)

iron(0) (EXP)

isoprenaline (ISO)

methapyrilene (EXP)

methimazole (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

nefazodone (EXP)

nickel sulfate (ISO)

ozone (ISO)

paracetamol (EXP)

phenformin (EXP)

phenobarbital (EXP)

phenylmercury acetate (ISO)

potassium cyanide (ISO)

quercetin (ISO)

SB 431542 (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

triphenyl phosphate (EXP)

urethane (ISO)

valdecoxib (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:21873635

Genomics

Comparative Map Data

Fam117b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	68,834,334 - 68,902,543 (+)	NCBI		GRCr8
mRatBN7.2	9	61,340,284 - 61,418,531 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	61,340,249 - 61,408,483 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	69,840,399 - 69,908,549 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	74,955,951 - 75,024,103 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	73,274,661 - 73,342,815 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	66,716,969 - 66,784,487 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	66,716,969 - 66,784,487 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	66,520,071 - 66,596,356 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	58,476,287 - 58,544,228 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	58,622,696 - 58,688,285 (+)	NCBI
Celera	9	58,775,417 - 58,842,774 (+)	NCBI		Celera
Cytogenetic Map	9	q31	NCBI

FAM117B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	202,634,969 - 202,769,757 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	202,634,969 - 202,769,757 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	203,499,692 - 203,634,480 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	203,208,456 - 203,342,725 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	2	197,252,014 - 197,387,230 (+)	NCBI		Celera
Cytogenetic Map	2	q33.2	NCBI
HuRef	2	195,346,934 - 195,481,383 (+)	NCBI		HuRef
CHM1_1	2	203,506,619 - 203,641,107 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	203,116,388 - 203,251,211 (+)	NCBI		T2T-CHM13v2.0

Fam117b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	59,952,165 - 60,024,507 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	59,952,165 - 60,024,505 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	59,913,006 - 59,985,348 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	59,913,006 - 59,985,346 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	59,969,850 - 60,042,190 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	59,857,552 - 59,929,893 (+)	NCBI		MGSCv36	mm8
Celera	1	60,428,884 - 60,500,816 (+)	NCBI		Celera
Cytogenetic Map	1	C2	NCBI
cM Map	1	30.44	NCBI

Fam117b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955457	12,107,141 - 12,180,614 (-)	NCBI	ChiLan1.0	ChiLan1.0

FAM117B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	105,265,851 - 105,400,190 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	105,280,848 - 105,415,187 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	89,896,400 - 90,030,724 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	208,043,335 - 208,177,158 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	208,042,146 - 208,173,180 (+)	Ensembl	panpan1.1		panPan2

FAM117B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	11,583,542 - 11,668,488 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	11,583,684 - 11,661,903 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	12,467,063 - 12,552,009 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	11,520,177 - 11,605,348 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	11,520,315 - 11,599,177 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	11,476,433 - 11,561,749 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	11,448,107 - 11,533,023 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	11,441,918 - 11,526,872 (+)	NCBI		UU_Cfam_GSD_1.0

Fam117b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	159,783,034 - 159,876,695 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936726	1,753,652 - 1,843,405 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936726	1,753,318 - 1,846,977 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FAM117B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	106,183,205 - 106,284,313 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	106,183,217 - 106,284,318 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	117,639,859 - 117,740,819 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FAM117B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	88,370,979 - 88,513,138 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666040	110,878,963 - 111,018,660 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fam117b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624765	13,701,345 - 13,782,952 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624765	13,661,928 - 13,782,962 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Fam117b
339 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	967
Count of miRNA genes:	344
Interacting mature miRNAs:	458
Transcripts:	ENSRNOT00000031261
Prediction methods:	Microtar, Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7411571	Bw138	Body weight QTL 138	14.3	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	9	32535505	77535505	Rat
1300180	Bw14	Body weight QTL 14	3.776		body mass (VT:0001259)	body weight (CMO:0000012)	9	23754024	61381613	Rat
11353957	Bmd92	Bone mineral density QTL 92		0.01	tibia mineral mass (VT:1000283)	volumetric bone mineral density (CMO:0001553)	9	46114199	91114199	Rat
631680	Cm11	Cardiac mass QTL 11	3.1	0.00089	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	9	20430519	65430519	Rat
70218	Cm28	Cardiac mass QTL 28	8.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	25268044	79271759	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	56771635	101771635	Rat
631643	Bp120	Blood pressure QTL 120	3	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	22071200	67071200	Rat
12879506	Pur33	Proteinuria QTL 33			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	44649921	89649921	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	25661188	100929786	Rat
1598849	Memor17	Memory QTL 17	2.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	9	49968546	71098346	Rat
10058949	Gmadr5	Adrenal mass QTL 5	2	0.014	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	9	42791513	87976209	Rat
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	48598251	93598251	Rat
2303170	Bp332	Blood pressure QTL 332	3.73	0.027	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	55847841	77026453	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	36962359	92058970	Rat
61352	Bp34	Blood pressure QTL 34	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	42495343	79271511	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	58163035	100929646	Rat
1598834	Memor11	Memory QTL 11	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	9	36962359	77814038	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	22071169	86369743	Rat
7207814	Bmd91	Bone mineral density QTL 91	3.5		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	9	23754144	83851531	Rat
6903941	Pur31	Proteinuria QTL 31		0.036	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	9	40194188	85194188	Rat
2303180	Bp333	Blood pressure QTL 333		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	56627713	78595166	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	36962359	95410867	Rat
11353949	Bp393	Blood pressure QTL 393			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	40194188	85194188	Rat
11353951	Bp394	Blood pressure QTL 394			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	44649921	89649921	Rat
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
1300134	Bp185	Blood pressure QTL 185	3.73		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	61381434	104821652	Rat
1331757	Cdexp1	CD45RC expression in CD8 T cells QTL 1	4.3		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	9	1024537	67509080	Rat
7411656	Foco26	Food consumption QTL 26	9.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	32535505	77535505	Rat
1578659	Tspe1	Trichinella spiralis expulsion QTL 1	4.8		parasite quantity (VT:0010441)	logarithm of the intestinal adult Trichinella spiralis count (CMO:0002024)	9	61381434	65691299	Rat
1641894	Alcrsp12	Alcohol response QTL 12			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	27468639	72468639	Rat

Markers in Region

D9Rat16

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	9	68,875,497 - 68,875,676 (+)	Marker Load Pipeline
mRatBN7.2	9	61,381,434 - 61,381,613 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	66,757,444 - 66,757,620	NCBI	Rnor6.0
Rnor_5.0	9	66,570,118 - 66,570,294	UniSTS	Rnor5.0
RGSC_v3.4	9	58,516,719 - 58,516,896	RGD	RGSC3.4
RGSC_v3.4	9	58,516,720 - 58,516,896	UniSTS	RGSC3.4
RGSC_v3.1	9	58,663,702 - 58,663,878	RGD
Celera	9	58,815,886 - 58,816,062	UniSTS
RH 3.4 Map	9	495.2	UniSTS
RH 3.4 Map	9	495.2	RGD
RH 2.0 Map	9	574.9	RGD
SHRSP x BN Map	9	42.2298	RGD
Cytogenetic Map	9	q31	UniSTS

RH133076

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	61,408,705 - 61,408,916 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	66,784,710 - 66,784,920	NCBI	Rnor6.0
Rnor_5.0	9	66,596,579 - 66,596,789	UniSTS	Rnor5.0
RGSC_v3.4	9	58,544,451 - 58,544,661	UniSTS	RGSC3.4
Celera	9	58,842,997 - 58,843,207	UniSTS
RH 3.4 Map	9	515.3	UniSTS
Cytogenetic Map	9	q31	UniSTS

BE107857

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	61,390,173 - 61,390,366 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	66,766,179 - 66,766,371	NCBI	Rnor6.0
Rnor_5.0	9	66,578,074 - 66,578,266	UniSTS	Rnor5.0
RGSC_v3.4	9	58,525,452 - 58,525,644	UniSTS	RGSC3.4
Celera	9	58,824,453 - 58,824,645	UniSTS
RH 3.4 Map	9	495.8	UniSTS
Cytogenetic Map	9	q31	UniSTS

RH137964

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	61,397,122 - 61,397,330 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	66,773,127 - 66,773,334	NCBI	Rnor6.0
Rnor_5.0	9	66,585,022 - 66,585,229	UniSTS	Rnor5.0
RGSC_v3.4	9	58,532,400 - 58,532,607	UniSTS	RGSC3.4
Celera	9	58,831,401 - 58,831,608	UniSTS
RH 3.4 Map	9	514.9	UniSTS
Cytogenetic Map	9	q31	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039083858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039083860	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC129370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000031261 ⟹ ENSRNOP00000029910

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	61,340,249 - 61,408,483 (+)	Ensembl
Rnor_6.0 Ensembl	9	66,716,969 - 66,784,487 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000111864 ⟹ ENSRNOP00000083133

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	61,340,249 - 61,408,483 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113257 ⟹ ENSRNOP00000093486

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	61,340,269 - 61,406,212 (+)	Ensembl

RefSeq Acc Id:

NM_001108797 ⟹ NP_001102267

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	68,834,354 - 68,902,543 (+)	NCBI
mRatBN7.2	9	61,340,284 - 61,408,485 (+)	NCBI
Rnor_6.0	9	66,716,969 - 66,784,487 (+)	NCBI
Rnor_5.0	9	66,520,071 - 66,596,356 (+)	NCBI
RGSC_v3.4	9	58,476,287 - 58,544,228 (+)	RGD
Celera	9	58,775,417 - 58,842,774 (+)	RGD

Sequence:

show sequence

AGGAGGTCCCCAGAGCAGGGTCGGCCCTCGGCGGAGAAGAGGAGCCCCAGCGCCCCGGTGTGCA
AAGCAGGTGACAAAACACGCCCACCTTCCTCCAGCCCCTCCAGCATTATCCGGCGTACTTCCTC
CCTGGATACCCTTGCAGCTCCATACCTTGCTGGGCACTGGCCCCGAGACAGTCGTGGGCAAGCC
ACACCCTGCATGAGGGACAAGGCCACACAGACCGAGAGTGCGTGGGCTGAAGAGTATGCTGAAA
AGAAGAAAGGGTCTCATAAACGCTCATCATCCTGGGGCAGTACAGAACAGCTTAAAGAGATTGC
AAAATTACGCCAGCAACTGCAGAGAAGCAAACACAGCAGCCGTCACCATCGAGATAAAGAAAGG
CAGTCTCCATTCCATGGCAACCATGCAGCTATTAACCAGAGCCAGGCTCCTGCTCCAAAGAGCA
CGCTCATTCCCGCTGGCCCCATCACCAAGTCCTCAGGCTCCCGGTTCCGGAACAGTGTGGAAGG
GCTGAACCAGGAGATCGAGATCATAATCAAAGAGACAGGGGAGAAGGAAGAACAGCTGATTCCA
CAAGATATCCCAGATGGTCATCGTGCGCCTCCACCCCTCGCACAGAGAAGCAGCAGCACACGCA
GCATTGACACACAGACTCCTGGGGGTGCAGACAAGGGAAGCAACAACAGCAGCCGCTCTCAGTC
TGTGTCCCCGACATCCTTCCTCACCATCTCTCATGAAGGCAGTGAGGAGAGTCCCTGTTCAGCT
GACGACCTGCTTGCCGATCCCAGAGATAAAGACAATGGAAACAACTCTCCTTTGCCAAAATATG
CAACCTCACCAAAACCTAACAACAGTTACATGTTCAAAAGGGAACCTCCAGAGGGCTGTGAAAG
GGTCAAAGTCTTTGAGGAATGCTCGCCAAAGCAACTTCATGAGATTCCAGCCTTTTACTGTCCC
GACAAAAACAAGGTGAATTTTATTCCTAAAAGTGGCTCTGCTTTCTGCCTCGTGAGTATCCTCA
AACCACTTCTTCCTACACCAGATCTTACCCTCAAGGGCTCTGGTCACAGCCTGACCGTCACCAC
TGGCATGACCACCACTTTGCTCCAGCCCATCTCTATGACCTCCCTGTCTACAAACACAGAGCAA
GACCGGGTATCTCGAGGAACCAGTACAGTCCTGCCGTCCGCTTCCCTCCATGCACCACCAGAAC
CCATCGAGGAAGCTGAAGGATAGGGCTCAGCTTGAGCTATGGGTGCTGGGAATTAAGAACCCTG
CAGGTCACATGACTGTGATGGTATCATGTCCTCCCGGTTGGCTGTGAAGTGCTTTGGCTTTCCA
GTGATGTGAAACAGCAAGGCTCCTGGAAGGACTCGTGGTCCCCTGAGTGCTCTGCCCTGCACGT
GAAGGCCACTGACGTGCTTCACCTTCTTGGCCTTGAAGCACCAGCTGAAACCTGAAAGGTCTCT
TCTTTACTTTTGGAGGAACAAAATCACATTTTCATTTGTTTTCAAATTAGACCTGTTTAAAAAC
AAAACAAAGACCCACAAAACCGGATCCCTGCAAACATAATTTCTGAAGGGAGATATGATTGATG
CTGCAAGAAAATCATCTTTTATATGAAAACGACTATTTTATAATACCAATGTCACATTTTCTCA
AAGTAGCAAACAGGACGTTCCAATGATCCTCTGGTGGCCTCTGTTTCTTGTTTCCTTTTTCTAG
ATATTGCTTTTCTCAGCTGTTTTCAGCTTTGGGACCAAAGGGATTGCTGACATTTCCCCAGCAA
TGTCAATCTCATGACTGTGTTCTTCTCCCAAGTAAGAATTGATAGGTAAATGCATTGAACCAAG
TATATATAAAAAAGATCAAAAGCAATATTCGTACATTATGTGATTTATGTTTTTTTATGTCAAA
AGTTTGTGATTTGAGTGAAGTATTTGTAAACTGCTGTTTTCTGAACTATCCCTGTCCACACTTC
ACCTTGTGGTCAGTCAGTCTGAAGACAGGTTGCTTTAACAGTCAGTGAGCCAAAAGAAACTCTG
AAGTGTGGATTGTTAGCTAGGAGTATGGAGCTCTCTGGTCTTCTGTGAGCTGTGTGTCCCGTGG
TGCCCTCCCCGCCGGGTGTCAGTCTAACTTTGATCATCACTGTATCATATAGCCCCAAGAGACC
CTGAAAAGGCTGTGCATGGATTCCCTCCTCTGCTTCTGTGGTGGTGTTGTCTTGTGGATTTGGT
CAGGGTTAGTAGTTTTCCAAGAGTGTGATCCATTGAGTAGCAATTGGGAGCTGCAGAAATCTTT
TGAGGACTGACTTCCTTCATGTGTTGGCGCTGTGATTTGCTACTTACAGATTTTGCTAGTTTCT
TCTCCAACATTCCATACACTGGGGGAAAGACAAGAGGCTGGGAGCTTAGGCAGCAGGTACCTTT
GAAAAGTATACAGTTTTGGATTTGAGCTCATCTGGTAACCATTGCCAGTATCACATGACAGTAT
TTAATTTCTAGGTGCGTGATAATAAAATTAAGGAGCTGCTCTTTAGAAATGAATTCCATCAGTG
TTGGTAAAGCACTGTTTTAATACATGCTAACTTATACTGCTGCATACAACAGGTGGATGGCAAG
CCCTGCATGAGAGGGACACAGTTTTGAAGGCGAATTCCATCCACTGGTCCAAGTCATTCCATCA
GGAGAAACCAAGAGATAGCAGTACATCTTCTTGGCAAGGTTTTTGTCACCTCAGGATGCCTCGG
AAACTTAAAGTAGGCTCTGCTCAGCTTTAAGTAAGGATATTTAGGTTTATTGGATAAATTCAAA
CATCTAAGTAAAATCCATCAGTTTTGGTTGGGAAAACTGAAACTTTTTGGTACTTGCCACCCAA
AGCTTAACTTCTGGGAACTAGTAAATCATAGCTTCTTAGTCAGTAAAAGCCTCAGTTGTTTGGT
GTGTAGGCTTTTTGTTTGGTGGGTTTTTTTTGTACCTTGATTTTTCTCCCTGTCGGGCCTTTTG
ACTTTACCATTTTATCAGGATCCAGAAGTACAGAAGAAAGAGGACTGGCAGTCCATTGAGCTGA
CCTGAAGGGAGAGGAGGCATTTAAAAGCAAGGGTTCTTGTTTTGTTTGTTTTTGAGGTGGCTCT
TATTATGTAGCCCAGGCTGGCCTGGCACTCATGCCTCTCCCAAGTGCTGGGATTAGTGGCGTGG
GCCACTGCACCATGCGTGTCTTCTTTTTAATGCTGTGGTTCCCCACCTGAATGCTGTCAAGTGG
GTGTTCTTCTTCCTTATCTATACCACCTCTTCTCTCGATTTACAAGTATAGTTTACTCTGCAAT
AGATTTCTTCCCTTTTCTGTTATACTTGTTTGGCCTCGTCCTTGAAATAACACAGAGAGGGACA
GGTTTCAGGTCAGCATCTGCTCCTAGAAGTAGAACTTAAGTTTGAGGTTTGGCTGGAAGAAGAC
TGTGAATTTGTAAGTAAATGAATTATATGGTGACCAAACACTCCTGAGATCTGAAGAAAAACAA
AAAAGGTCTATGTCCAAAAAAACAACTCTTAACTGCCAGGGCCAAAGGGCTAATTTTTAAGCAT
ATGAGCTTTATTTGCAGTCTTAGCATATATTAACCGTAGATCCACCTAGCTGTTTTATTTAACT
CTTAATTCCCAGGTGCTTGGTTTTAAAAATGGGTCTACTCTTAGTAGAGTGGGCATGATTACAC
TGACAAGCCACACTCCATAATTAGGTTATTCTGTAGAAACTGTACAGAGGTAGAGTAGCTTCAG
TGCAAATACAGTCTTTCCCAGTGCTGGGGATGAAACCCAGGGCCTCGTGCATGCTGAGCAAGTG
CTCTGTCGCTGGCTTATTTCCCAGTTCCTCATTTAAATTCTTAATTAAAAACCATTTTGTTCCA
TTGCAGTAAAAGTGGGTGGCATGTGTATTTTTTGGCTAAAGCACTGTTCCTGGCCCATCTTAGT
TCTACTTGACCCTCCAGCAGTTTCCTCCCTGCGGTGATAAACCTCAGGTTTATAGCTTCTGACT
CGGTAAGTCTGTTACTTATCACTGGTTTACAGGCAGTTGTGTTTAAAACACTAGTAGGTTTGCT
TTCTTTGGTTAAATATAGTGGGAATGTCAATTTTTTTTCTACCAGGTTCTTCATTTTTGTTTAC
AGGGTTTCTTAGACCTAGGACCATAACCAATCTGCCTCTCTGTCTGTAGATGCTGTTGCTGACT
GGGGTGGGTCTGGCAACGGGGAAGGCTGCTTTTTATTCTTACTTTTTAATGTTTTCATTAAAGA
AACAGTCAGCTTTTCCTAGAAGGTCTAAAAAAAAATGGCACAATATAGAGCTTTCTCTGTATGG
GATTTGAACTGAGATCTTGAGGTTTTCTTTCAAGGAAACTAAAGTAAAATTGACATTACTGAAT
TTGTGAAGTTGAGATTCATTCCTAAATACTGGGTTTGGGGTGTGTCAAAACTGGACCAGTGGAA
GTGCTGAATTTGCAAAGTAAAGCCAAGATACTTAAGTCTGCACTTTAAGGCTTCTGGTCGCTCT
GCCTTCATTAGTGACTCCGCAGAGTGGCTCTGAACAGTATTTTGTTTATACAGTCCTGTTGGAG
ATATATAATTTATGTTTTTTAAACTCTGCATCTTTGTCTCTGTTGGTGTAAATCTTTTTTAATG
CAATTTTTTAAAGTTATAACAGAATTCTTCCCCCAAAAAAACAGCATTTCCAGCGATGATAAGT
ATTGTGTTGTGGACTGTCCCTGCACCTGAGCACTTACTGCTTCCGACAGGGGGAGACTCCTGTG
TTCAAATAAAGTCTGTTGTTCTC

hide sequence

RefSeq Acc Id:

XM_039083858 ⟹ XP_038939786

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	68,834,334 - 68,902,543 (+)	NCBI
mRatBN7.2	9	61,340,291 - 61,408,485 (+)	NCBI

RefSeq Acc Id:

XM_039083860 ⟹ XP_038939788

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	68,835,178 - 68,902,543 (+)	NCBI
mRatBN7.2	9	61,341,104 - 61,408,485 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102267	(Get FASTA)	NCBI Sequence Viewer
	XP_038939786	(Get FASTA)	NCBI Sequence Viewer
	XP_038939788	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL98943	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000029910
	ENSRNOP00000029910.6
	ENSRNOP00000083133
	ENSRNOP00000083133.1
	ENSRNOP00000093486.1

RefSeq Acc Id:

NP_001102267 ⟸ NM_001108797

- UniProtKB:

F1M8D5 (UniProtKB/TrEMBL), A0A8I6ALF3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRDKATQTESAWAEEYAEKKKGSHKRSSSWGSTEQLKEIAKLRQQLQRSKHSSRHHRDKERQSP
FHGNHAAINQSQAPAPKSTLIPAGPITKSSGSRFRNSVEGLNQEIEIIIKETGEKEEQLIPQDI
PDGHRAPPPLAQRSSSTRSIDTQTPGGADKGSNNSSRSQSVSPTSFLTISHEGSEESPCSADDL
LADPRDKDNGNNSPLPKYATSPKPNNSYMFKREPPEGCERVKVFEECSPKQLHEIPAFYCPDKN
KVNFIPKSGSAFCLVSILKPLLPTPDLTLKGSGHSLTVTTGMTTTLLQPISMTSLSTNTEQDRV
SRGTSTVLPSASLHAPPEPIEEAEG

hide sequence

Ensembl Acc Id:

ENSRNOP00000029910 ⟸ ENSRNOT00000031261

RefSeq Acc Id:	XP_038939786 ⟸ XM_039083858
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZYM6 (UniProtKB/TrEMBL), A0A8I6ALF3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038939788 ⟸ XM_039083860
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000083133 ⟸ ENSRNOT00000111864

Ensembl Acc Id:

ENSRNOP00000093486 ⟸ ENSRNOT00000113257

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M8D5-F1-model_v2	AlphaFold	F1M8D5	1-345	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307676	AgrOrtholog
BioCyc Gene	G2FUF-27389	BioCyc
Ensembl Genes	ENSRNOG00000022066	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000031261	ENTREZGENE
	ENSRNOT00000031261.6	UniProtKB/TrEMBL
	ENSRNOT00000111864	ENTREZGENE
	ENSRNOT00000111864.1	UniProtKB/TrEMBL
	ENSRNOT00000113257.1	UniProtKB/TrEMBL
InterPro	Glcci1/FAM117	UniProtKB/TrEMBL
KEGG Report	rno:363236	UniProtKB/TrEMBL
NCBI Gene	363236	ENTREZGENE
PANTHER	PTHR14972	UniProtKB/TrEMBL
	PTHR14972:SF6	UniProtKB/TrEMBL
Pfam	FAM117	UniProtKB/TrEMBL
PhenoGen	Fam117b	PhenoGen
RatGTEx	ENSRNOG00000022066	RatGTEx
UniProt	A0A8I5ZYM6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ALF3	ENTREZGENE, UniProtKB/TrEMBL
	A6IPB7_RAT	UniProtKB/TrEMBL
	F1M8D5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-09-26	Fam117b	family with sequence similarity 117, member B	Als2cr13	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 13 (human)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-05-15	Als2cr13	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 13 (human)	Als2cr13	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 13	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-26	Als2cr13	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 13	Als2cr13_predicted	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 13 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Als2cr13_predicted	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 13 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar