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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:1614310 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FAM117B mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | affects expression | ISO | RGD:1614310 | 6480464 | 1, 2-Dimethylhydrazine affects the expression of FAM117B mRNA | CTD | PMID:22206623 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | RGD:1614310 | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,4,7,8-Pentachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:21724226 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1614310 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FAM117B mRNA | CTD | PMID:19770486 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FAM117B mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FAM117B mRNA | CTD | PMID:21215274 more ... | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:21724226 | 4,4'-sulfonyldiphenol | decreases expression | ISO | RGD:1614310 | 6480464 | bis(4-hydroxyphenyl)sulfone results in decreased expression of FAM117B mRNA | CTD | PMID:33297965 | 4-hydroxyphenyl retinamide | decreases expression | ISO | RGD:1614310 | 6480464 | Fenretinide results in decreased expression of FAM117B mRNA | CTD | PMID:28973697 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of FAM117B mRNA | CTD | PMID:28959563 | all-trans-retinoic acid | decreases expression | ISO | RGD:1317004 | 6480464 | Tretinoin results in decreased expression of FAM117B mRNA | CTD | PMID:33167477 | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of FAM117B mRNA | CTD | PMID:30779732 | aristolochic acid A | decreases expression | ISO | RGD:1317004 | 6480464 | aristolochic acid I results in decreased expression of FAM117B mRNA | CTD | PMID:33212167 | arsane | affects expression | ISO | RGD:1317004 | 6480464 | Arsenic affects the expression of FAM117B mRNA | CTD | PMID:18414638 | arsenic atom | affects expression | ISO | RGD:1317004 | 6480464 | Arsenic affects the expression of FAM117B mRNA | CTD | PMID:18414638 | arsenous acid | increases expression | ISO | RGD:1317004 | 6480464 | Arsenic Trioxide results in increased expression of FAM117B mRNA | CTD | PMID:20458559 | benzo[a]pyrene | increases expression | ISO | RGD:1614310 | 6480464 | Benzo(a)pyrene results in increased expression of FAM117B mRNA | CTD | PMID:21569818 | benzo[a]pyrene | decreases methylation | ISO | RGD:1317004 | 6480464 | Benzo(a)pyrene results in decreased methylation of FAM117B promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | RGD:1614310 | 6480464 | Benzo(a)pyrene results in decreased expression of FAM117B mRNA | CTD | PMID:22228805 | benzo[a]pyrene diol epoxide I | increases expression | ISO | RGD:1317004 | 6480464 | 7 more ... | CTD | PMID:26238291 | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:1317004 | 6480464 | Diethylhexyl Phthalate results in increased expression of FAM117B protein | CTD | PMID:31163220 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FAM117B mRNA | CTD | PMID:25181051 more ... | cadmium atom | multiple interactions | ISO | RGD:1317004 | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of FAM117B mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | RGD:1317004 | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of FAM117B mRNA | CTD | PMID:35301059 | caffeine | increases phosphorylation | ISO | RGD:1317004 | 6480464 | Caffeine results in increased phosphorylation of FAM117B protein | CTD | PMID:35688186 | carbon nanotube | decreases expression | ISO | RGD:1614310 | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | cisplatin | decreases expression | ISO | RGD:1317004 | 6480464 | Cisplatin results in decreased expression of FAM117B mRNA | CTD | PMID:27594783 | coumarin | increases phosphorylation | ISO | RGD:1317004 | 6480464 | coumarin results in increased phosphorylation of FAM117B protein | CTD | PMID:35688186 | cyclosporin A | decreases expression | ISO | RGD:1317004 | 6480464 | Cyclosporine results in decreased expression of FAM117B mRNA | CTD | PMID:20106945 | cyclosporin A | decreases expression | ISO | RGD:1614310 | 6480464 | Cyclosporine results in decreased expression of FAM117B mRNA | CTD | PMID:19770486 | diarsenic trioxide | increases expression | ISO | RGD:1317004 | 6480464 | Arsenic Trioxide results in increased expression of FAM117B mRNA | CTD | PMID:20458559 | dioxygen | increases expression | ISO | RGD:1317004 | 6480464 | Oxygen deficiency results in increased expression of FAM117B mRNA | CTD | PMID:26516004 | dorsomorphin | multiple interactions | ISO | RGD:1317004 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FAM117B mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | RGD:1317004 | 6480464 | Doxorubicin results in decreased expression of FAM117B mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of FAM117B mRNA | CTD | PMID:29391264 | ethanol | affects splicing | ISO | RGD:1614310 | 6480464 | Ethanol affects the splicing of FAM117B mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | decreases expression | ISO | RGD:1317004 | 6480464 | Ethyl Methanesulfonate results in decreased expression of FAM117B mRNA | CTD | PMID:23649840 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of FAM117B mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | RGD:1614310 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FAM117B mRNA | CTD | PMID:22206623 | formaldehyde | decreases expression | ISO | RGD:1317004 | 6480464 | Formaldehyde results in decreased expression of FAM117B mRNA | CTD | PMID:23649840 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of FAM117B mRNA | CTD | PMID:33387578 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of FAM117B mRNA | CTD | PMID:24136188 | hexadecanoic acid | decreases phosphorylation | ISO | RGD:1317004 | 6480464 | Palmitic Acid results in decreased phosphorylation of FAM117B protein | CTD | PMID:28073184 | hydrogen cyanide | increases expression | ISO | RGD:1614310 | 6480464 | Hydrogen Cyanide results in increased expression of FAM117B mRNA | CTD | PMID:33914522 | hydroquinone | decreases expression | ISO | RGD:1317004 | 6480464 | hydroquinone results in decreased expression of FAM117B mRNA | CTD | PMID:31256213 | iron atom | increases expression | EXP | | 6480464 | Iron deficiency results in increased expression of FAM117B mRNA | CTD | PMID:16629162 | iron(0) | increases expression | EXP | | 6480464 | Iron deficiency results in increased expression of FAM117B mRNA | CTD | PMID:16629162 | isoprenaline | increases expression | ISO | RGD:1614310 | 6480464 | Isoproterenol results in increased expression of FAM117B mRNA | CTD | PMID:20003209 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of FAM117B mRNA | CTD | PMID:30467583 | methyl methanesulfonate | decreases expression | ISO | RGD:1317004 | 6480464 | Methyl Methanesulfonate results in decreased expression of FAM117B mRNA | CTD | PMID:23649840 | methylmercury chloride | increases expression | ISO | RGD:1317004 | 6480464 | methylmercuric chloride results in increased expression of FAM117B mRNA | CTD | PMID:28001369 | nefazodone | decreases expression | EXP | | 6480464 | nefazodone results in decreased expression of FAM117B mRNA | CTD | PMID:24136188 | nickel sulfate | increases expression | ISO | RGD:1317004 | 6480464 | nickel sulfate results in increased expression of FAM117B mRNA | CTD | PMID:22714537 | ozone | multiple interactions | ISO | RGD:1614310 | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of FAM117B mRNA | CTD | PMID:34911549 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of FAM117B mRNA | CTD | PMID:33387578 | phenformin | increases expression | EXP | | 6480464 | Phenformin results in increased expression of FAM117B mRNA | CTD | PMID:31324951 | phenylmercury acetate | decreases expression | ISO | RGD:1317004 | 6480464 | Phenylmercuric Acetate results in decreased expression of FAM117B mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | RGD:1317004 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FAM117B mRNA | CTD | PMID:27188386 | potassium cyanide | increases expression | ISO | RGD:1614310 | 6480464 | Potassium Cyanide results in increased expression of FAM117B mRNA | CTD | PMID:33914522 | quercetin | decreases expression | ISO | RGD:1317004 | 6480464 | Quercetin results in decreased expression of FAM117B mRNA | CTD | PMID:21632981 | SB 431542 | multiple interactions | ISO | RGD:1317004 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FAM117B mRNA | CTD | PMID:27188386 | silver atom | decreases expression | ISO | RGD:1614310 | 6480464 | Silver results in decreased expression of FAM117B mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | RGD:1614310 | 6480464 | Silver results in decreased expression of FAM117B mRNA | CTD | PMID:27131904 | sunitinib | increases expression | ISO | RGD:1317004 | 6480464 | Sunitinib results in increased expression of FAM117B mRNA | CTD | PMID:31533062 | tetrachloromethane | increases expression | ISO | RGD:1614310 | 6480464 | Carbon Tetrachloride results in increased expression of FAM117B mRNA | CTD | PMID:31919559 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of FAM117B mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | ISO | RGD:1614310 | 6480464 | titanium dioxide results in decreased expression of FAM117B mRNA | CTD | PMID:29264374 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of FAM117B mRNA | CTD | PMID:33387578 | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of FAM117B mRNA | CTD | PMID:30589522 | urethane | increases expression | ISO | RGD:1317004 | 6480464 | Urethane results in increased expression of FAM117B mRNA | CTD | PMID:28818685 | valdecoxib | decreases expression | EXP | | 6480464 | valdecoxib results in decreased expression of FAM117B mRNA | CTD | PMID:24136188 | valproic acid | increases methylation | ISO | RGD:1317004 | 6480464 | Valproic Acid results in increased methylation of FAM117B gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | RGD:1317004 | 6480464 | Valproic Acid results in decreased expression of FAM117B mRNA | CTD | PMID:23179753 | valproic acid | affects expression | ISO | RGD:1317004 | 6480464 | Valproic Acid affects the expression of FAM117B mRNA | CTD | PMID:25979313 | |