Gene: Trak2 (trafficking kinesin protein 2) Rattus norvegicus
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Symbol: Trak2
Name: trafficking kinesin protein 2
Description: ENCODES a protein that exhibits enzyme binding; GABA receptor binding; kinesin binding; INVOLVED IN dendrite morphogenesis; dendritic transport of mitochondrion; endosome to lysosome transport; PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN axonal growth cone; cytoplasm; dendrite; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine
AGR Description: Exhibits several functions, including GABA receptor binding activity, TPR domain binding activity, and enzyme binding activity; involved in several processes, including dendritic transport of mitochondrion, endosome to lysosome transport, and generation of neurons; localizes to several cellular components, including the intracellular membrane-bounded organelle, neuron projection, and neuronal cell body; colocalizes with the early endosome; orthologous to human TRAK2 (trafficking kinesin protein 2).
Merged Description: Exhibits several functions, including GABA receptor binding activity, TPR domain binding activity, and enzyme binding activity; involved in several processes, including dendritic transport of mitochondrion, endosome to lysosome transport, and generation of neurons; localizes to several cellular components, including the intracellular membrane-bounded organelle, neuron projection, and neuronal cell body; colocalizes with the early endosome; orthologous to human TRAK2 (trafficking kinesin protein 2); PARTICIPATES IN mitochondria transport pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Als2cr3; amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 3; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3 homolog; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3 homolog (human); amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein homolog; GABA-A receptor interacting factor-1; GABA-A receptor-interacting factor 1; GRIF-1; MGC93214; O-GlcNAc transferase-interacting protein of 98 kDa; trafficking kinesin-binding protein 2; trafficking protein, kinesin binding 2
Orthologs:
Homo sapiens (human) : TRAK2 (trafficking kinesin protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Trak2 (trafficking protein, kinesin binding 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trak2 (trafficking kinesin protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TRAK2 (trafficking kinesin protein 2)
Canis lupus familiaris (dog) : TRAK2 (trafficking kinesin protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trak2 (trafficking kinesin protein 2)
Sus scrofa (pig) : TRAK2 (trafficking kinesin protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0965,698,706 - 65,763,351 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0965,505,448 - 65,570,090 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4957,474,682 - 57,540,751 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1957,624,566 - 57,661,312 (-)NCBI
Celera957,788,961 - 57,853,095 (-)NCBICelera
Cytogenetic Map9q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Trak2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620915
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.